Lymphoproliferative Disorders
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Subject Areas on Research
- 2010 update of EORTC guidelines for the use of granulocyte-colony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphoproliferative disorders and solid tumours.
- ADA2 deficiency: Clonal lymphoproliferation in a subset of patients.
- Acquired C1-inhibitor deficiency.
- Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome.
- An EBV-positive lymphoproliferative disorder after therapy with alemtuzumab.
- An approach to monoclonal gammopathies in the elderly.
- Candidate counterparts of Sézary cells and adult T-cell lymphoma-leukaemia cells in normal peripheral blood: an ultrastructural study with the immunogold method and monoclonal antibodies.
- Case 260: Endobronchial Posttransplantation Lymphoproliferative Disease.
- Causes of late mortality in pediatric liver transplant recipients.
- Cellular events in the differentiation of antibody-secreting cells.
- Concurrent classical Hodgkin lymphoma and plasmablastic lymphoma in a patient with chronic lymphocytic leukemia/small lymphocytic lymphoma treated with fludarabine: a dimorphic presentation of iatrogenic immunodeficiency-associated lymphoproliferative disorder with evidence suggestive of multiclonal transformability of B cells by Epstein-Barr virus.
- Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice.
- Critical care perspective on immunotherapy in lung transplantation.
- Cutaneous manifestations as presenting sign of autoimmune lymphoproliferative syndrome in childhood.
- Decreased survival in hepatitis C patients with monomorphic post-transplant lymphoproliferative disorder after liver transplantation treated with frontline immunochemotherapy.
- Defective natural killing activity but retention of lymphocyte-mediated antibody-dependent cellular cytotoxicity in patients with the X-linked lymphoproliferative syndrome.
- Deficiency of 5-lipoxygenase abolishes sex-related survival differences in MRL-lpr/lpr mice.
- Detection of immunoglobulin kappa light chain rearrangements by polymerase chain reaction. An improved method for detecting clonal B-cell lymphoproliferative disorders.
- Differences in V kappa gene utilization and VH CDR3 sequence among anti-DNA from C3H-lpr mice and lupus mice with nephritis.
- Dissociation of depletional induction and posttransplant lymphoproliferative disease in kidney recipients treated with alemtuzumab.
- Epstein-Barr virus and the elderly host.
- Epstein-Barr virus as an etiological agent in the pathogenesis of lymphoproliferative and aproliferative diseases in immune deficient patients.
- Epstein-Barr virus-associated lymphoproliferative disorder following autologous bone marrow transplantation for non-Hodgkin's lymphoma.
- Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder after high-dose immunosuppressive therapy and autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases.
- Epstein-Barr virus-related posttransplantation lymphoproliferative disorder involving pancreas allografts: histological differential diagnosis from acute allograft rejection.
- Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus.
- Factors associated with recurrent cytomegalovirus disease after small bowel transplantation.
- Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations.
- Fludarabine and cyclophosphamide with filgrastim support in patients with previously untreated indolent lymphoid malignancies.
- Function of a Foxp3 cis-element in protecting regulatory T cell identity.
- Gamma (immune) interferon produced by leukocytes from a patients with a T cell proliferation disease.
- Gamma (immune) interferon production by leukocytes from a patient with a TG cell proliferative disease.
- Hairy cell leukemia-associated familial lymphoproliferative disorder: immunologic abnormalities in unaffected family members.
- Herpes virus infections occur frequently following treatment with fludarabine: results of a prospective natural history study.
- IgG antinuclear antibodies with cross-reactive rheumatoid factor activity.
- Immunodeficiency diseases.
- Immunodeficiency.
- Increased beta 2-microglobulin (B2M) is useful in the detection of post-transplant lymphoproliferative disease (PTLD).
- Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II.
- Intravenous busulfan plus melphalan is a highly effective, well-tolerated preparative regimen for autologous stem cell transplantation in patients with advanced lymphoid malignancies.
- Isolated intestinal transplantation for intestinal failure.
- Low incidence of Epstein-Barr virus-associated posttransplantation lymphoproliferative disorders in 272 unrelated-donor umbilical cord blood transplant recipients.
- Low-dose chemotherapy for Epstein-Barr virus-positive post-transplantation lymphoproliferative disease in children after solid organ transplantation.
- Low-dose radiation for posttransplant lymphoproliferative disorder.
- Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice.
- Lymphocytic vasculitis involving the central nervous system occurs in patients with X-linked lymphoproliferative disease in the absence of Epstein-Barr virus infection.
- Lymphodepletional strategies in transplantation.
- Lymphoproliferative disease of granular lymphocytes.
- Lymphoproliferative disorders: CT findings in immunocompromised children.
- Malignancy after solid organ transplantation: an overview.
- Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment.
- Molecular analysis of spontaneous nephrotropic anti-laminin antibodies in an autoimmune MRL-lpr/lpr mouse.
- Morphologic examination of sequential bone marrow biopsies after nonmyeloablative stem cell transplantation complements molecular studies of donor engraftment.
- Multilocular thymic cysts in children with human immunodeficiency virus infection: clinical and pathologic aspects.
- NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors.
- Necrotizing lymphoid vasculitis in X-linked lymphoproliferative syndrome.
- Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies.
- Pediatric kidney transplantation at the University of Pittsburgh.
- Phenotypic abnormalities of splenic and bone marrow B cells in lpr and gld mice.
- Phenotypic and functional characterization of human malignant T cells.
- Polyclonal polymorphic B-cell lymphoproliferative disorder with prominent pulmonary involvement in children with acquired immune deficiency syndrome.
- Polymerase chain reaction amplification and in situ hybridization for the detection of human B-lymphotropic virus.
- Positron emission tomography with fluoro-2-deoxy-D-glucose (FDG-PET) in the staging of post transplant lymphoproliferative disorder in lung transplant recipients.
- Post-transplant lymphoproliferative disorder associated with immunosuppressive therapy for renal transplantation in rhesus macaques (Macaca mulatta).
- Posttransplant lymphoproliferative disorder after umbilical cord blood transplantation in children.
- Posttransplant lymphoproliferative disorder following nonmyeloablative allogeneic stem cell transplantation.
- Posttransplant lymphoproliferative disorder: incidence, presentation, and response to treatment in lung transplant recipients.
- Posttransplant lymphoproliferative disorders and Epstein-Barr virus prophylaxis.
- Prognostic significance of recurrent grade 1B rejection in the first year after pediatric cardiac transplantation: a case for reinstatement of the 1B rejection grade.
- Pulmonary lymphangioleiomyomatosis: CT findings.
- Risk of lymphoproliferative disorders after bone marrow transplantation: a multi-institutional study.
- Role of Epstein-Barr virus in the etiology of Burkitt's lymphoma.
- Second Allogeneic Hematopoietic Cell Transplantation for Patients with Fanconi Anemia and Bone Marrow Failure.
- Survival outcomes of allogeneic hematopoietic cell transplants with EBV-positive or EBV-negative post-transplant lymphoproliferative disorder, A CIBMTR study.
- T cells or active Epstein-Barr virus infection in the development of lymphoproliferative disease in human B cell-injected severe combined immunodeficient mice.
- T-cell-depleted autologous bone marrow transplantation therapy: analysis of immune deficiency and late complications.
- The importance of the Erk pathway in the development of linker for activation of T cells-mediated autoimmunity.
- The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity.
- The pathology of liver-localized post-transplant lymphoproliferative disease: a report of three cases and a review of the literature.
- The role of B cell abnormalities in the systemic autoimmune syndromes of lpr and gld mice.
- The role of the LAT-PLC-gamma1 interaction in T regulatory cell function.
- The secondary pulmonary lobule: normal and abnormal CT appearances.
- The viral and cellular microRNA targetome in lymphoblastoid cell lines.
- Transgenic expression of the viral FLIP MC159 causes lpr/gld-like lymphoproliferation and autoimmunity.
- Whole body hyperthermia and heat-sensitizing drugs: a pilot study in canine lymphoproliferative disease.
- X-linked lymphoproliferative disease (XLP): a model of impaired anti-viral, anti-tumor and humoral immune responses.
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Keywords of People
- Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor of Pediatrics, in the School of Medicine, Immunology
- Lagoo, Anand Shreeram, Professor of Pathology, Pathology
- Luftig, Micah Alan, Associate Professor of Molecular Genetics and Microbiology, Immunology