Macaca fascicularis

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  Subject Areas on Research

  • 1982 resident's essay award: the immunologic effects of lymphoid irradiation in human and non-human primates: cellular changes and the potential for renal transplantation. 
  • 4D11: The Second Mouse? 
  • A Highly Effective and Ultra-Long-Acting Anti-Glaucoma Drug, with a Novel Periorbital Delivery Method. 
  • A clinicopathologic study of dye laser photocoagulation on primate retina. 
  • A collagen-based nerve guide conduit for peripheral nerve repair: an electrophysiological study of nerve regeneration in rodents and nonhuman primates. 
  • A comparative evaluation of nasal and parenteral vaccine adjuvants to elicit systemic and mucosal HIV-1 peptide-specific humoral immune responses in cynomolgus macaques. 
  • A polyaxonal amacrine cell population in the primate retina. 
  • Adaptability to changes in temporal structure is fornix-dependent. 
  • Anatomic compression caused by high-volume convection-enhanced delivery to the brain. 
  • Anatomical identification of extracellularly recorded cells in large-scale multielectrode recordings. 
  • Ankyrin-B structurally defines terminal microdomains of peripheral somatosensory axons. 
  • Anticoagulant responses to thrombin are enhanced during regression of atherosclerosis in monkeys. 
  • Attenuation of neurovirulence, biodistribution, and shedding of a poliovirus:rhinovirus chimera after intrathalamic inoculation in Macaca fascicularis. 
  • Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates. 
  • CD154 blockade, sirolimus, and donor-specific transfusion prevents renal allograft rejection in cynomolgus monkeys despite homeostatic T-cell activation. 
  • COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models. 
  • Catecholaminergic innervation of the hippocampus in the cynomolgus monkey. 
  • Characteristics of the specific cell-mediated immune response in human immunodeficiency virus infection. 
  • Composite tissue allotransplantation: development of a preclinical model in nonhuman primates. 
  • Cone inputs in macaque primary visual cortex. 
  • Constraints on the source of short-term motion adaptation in macaque area MT. I. the role of input and intrinsic mechanisms. 
  • Constraints on the source of short-term motion adaptation in macaque area MT. II. tuning of neural circuit mechanisms. 
  • Continuous complement (C) inhibition using soluble C receptor type 1 (sCR1): effect on hyperacute rejection (HAR) of pig-to-primate cardiac xenografts. 
  • Contrasting effects of Western vs Mediterranean diets on monocyte inflammatory gene expression and social behavior in a primate model. 
  • Correlated firing among major ganglion cell types in primate retina. 
  • Design of helical, oligomeric HIV-1 fusion inhibitor peptides with potent activity against enfuvirtide-resistant virus. 
  • Detection of infusate leakage in the brain using real-time imaging of convection-enhanced delivery. 
  • Determination of Real Time in Vivo Drug Receptor Occupancy for a Covalent Binding Drug as a Clinical Pharmacodynamic Biomarker by Immunocapture-LC-MS/MS. 
  • Differential expression of muscarinic acetylcholine receptors across excitatory and inhibitory cells in visual cortical areas V1 and V2 of the macaque monkey. 
  • Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton's Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers. 
  • Distribution of GABAergic neurons and axon terminals in the macaque striate cortex. 
  • Dual stem loops within the poliovirus internal ribosomal entry site control neurovirulence. 
  • Dust accumulation in the canopy: a potential cause of dental microwear in primates. 
  • Effect of continuous complement inhibition using soluble complement receptor type 1 on survival of pig-to-primate cardiac xenografts. 
  • Effect of progestin on the ovarian epithelium of macaques: cancer prevention through apoptosis? 
  • Effects of IL-1 on hematopoietic progenitors after myelosuppressive chemoradiotherapy. 
  • Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques. 
  • Effects of hematopoietic growth factors following myeloablation in a primate model. 
  • Effects of interleukin-1 on hematopoietic progenitors: evidence of stimulatory and inhibitory activities in a primate model. 
  • Effects of interleukin-3 on hematopoietic recovery after 5-fluorouracil or cyclophosphamide treatment of cynomolgus primates. 
  • Effects of the new ethacrynic acid derivative SA9000 on intraocular pressure in cats and monkeys. 
  • Effects of the new ethacrynic acid oxime derivative SA12590 on intraocular pressure in cats and monkeys. 
  • Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates. 
  • Enrichment of peripheral blood stem cells in a primate model following administration of a single dose of rh-IL-1 beta. 
  • Evaluation of a delivery system providing long-term release of cyclosporine. 
  • Experimental transvitreal cyanoacrylate retinopexy in a primate model. 
  • Expression of the protein tyrosine phosphatase, phosphatase of regenerating liver 1, in the outer segments of primate cone photoreceptors. 
  • Factors contributing to preferential motor reinnervation in the primate peripheral nervous system. 
  • Factors that influence peripheral nerve regeneration: an electrophysiological study of the monkey median nerve. 
  • Fornix transected macaques make fewer perseverative errors than controls during the early stages of learning conditional visuovisual discriminations [corrected]. 
  • Fornix transection selectively impairs fast learning of conditional visuospatial discriminations. 
  • Functional Clusters of Neurons in Layer 6 of Macaque V1. 
  • Functional connectivity in the retina at the resolution of photoreceptors. 
  • Gain modulation by nicotine in macaque v1. 
  • Hemodynamic stress and experimental aortoiliac atherosclerosis. 
  • High-sensitivity rod photoreceptor input to the blue-yellow color opponent pathway in macaque retina. 
  • Hyperimmunization of non-human primates with BCG-CW and cultured human glioma-derived cells. Production of reactive antisera and absence of EAE induction. 
  • Identification and quantification of a messenger ribonucleic acid induced by polynuclear aromatic hydrocarbons--using a cloned human cytochrome P-450 gene. 
  • Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases. 
  • Identification of a Retinal Circuit for Recurrent Suppression Using Indirect Electrical Imaging. 
  • IgG is a prominent component of cynomolgus antiporcine natural xenoantibody. 
  • Immune distribution and localization of phosphoantigen-specific Vgamma2Vdelta2 T cells in lymphoid and nonlymphoid tissues in Mycobacterium tuberculosis infection. 
  • Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance. 
  • Immunization against SIVmne in macaques using multigenic DNA vaccines. 
  • Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. 
  • In vitro metabolism of 10-(3-chlorophenyl)-6,8,9,10-tetrahydrobenzo[b][1,8]naphthyridin-5(7H)- one, a topical antipsoriatic agent. Use of precision-cut rat, dog, monkey and human liver slices, and chemical synthesis of metabolites. 
  • Increased epidermal growth factor-like ligands are associated with elevated vascular nicotinamide adenine dinucleotide phosphate oxidase in a primate model of atherosclerosis. 
  • Increased plasma oxidized phospholipid:apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid-lowering: a potential biomarker of early atherosclerosis regression. 
  • Induction of lethal experimental allergic encephalomyelitis in nonhuman primates and guinea pigs with human glioblastoma multiforme tissue. 
  • Interleukin-15 receptor blockade in non-human primate kidney transplantation. 
  • Intrinsic connections of macaque striate cortex: afferent and efferent connections of lamina 4C. 
  • Intrinsic connections of macaque striate cortex: axonal projections of cells outside lamina 4C. 
  • Jaw-muscle architecture and mandibular morphology influence relative maximum jaw gapes in the sexually dimorphic Macaca fascicularis. 
  • Limited breadth of the protective immunity elicited by simian immunodeficiency virus SIVmne gp160 vaccines in a combination immunization regimen. 
  • Location of the PH-20 protein on acrosome-intact and acrosome-reacted spermatozoa of cynomolgus macaques. 
  • Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function. 
  • Loss of hippocampal acetylcholinesterase staining after fornix lesion in the monkey. 
  • Mechanisms regulating variability of the single photon responses of mammalian rod photoreceptors. 
  • Microangiopathic retinopathy in experimental diabetic monkeys. 
  • Mnemonic Introspection in Macaques Is Dependent on Superior Dorsolateral Prefrontal Cortex But Not Orbitofrontal Cortex. 
  • Molecular and cellular profiling of acute responses to total body radiation exposure in ovariectomized female cynomolgus macaques. 
  • Monkey median nerve repaired by nerve graft or collagen nerve guide tube. 
  • Monte Carlo methods for localization of cones given multielectrode retinal ganglion cell recordings. 
  • Morphology of retinogeniculate axons in the macaque. 
  • Movement of cynomolgus and rhesus monkey spermatozoa collected from the lower female reproductive tract. 
  • Non-human to human organ transplantation: its biologic basis and a potential role for radiation therapy. 
  • Nonclinical Safety and Toxicokinetics of MnTnBuOE-2-PyP5+ (BMX-001). 
  • Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma. 
  • Optical imaging of bipolar cortical stimulation. 
  • Optical imaging of visual cortex epileptic foci and propagation pathways. 
  • Orthogonal micro-organization of orientation and spatial frequency in primate primary visual cortex. 
  • Partial ablations of the flocculus and ventral paraflocculus in monkeys cause linked deficits in smooth pursuit eye movements and adaptive modification of the VOR. 
  • Pathogenicity of simian-human immunodeficiency virus SHIV-89.6P and SIVmac is attenuated in cynomolgus macaques and associated with early T-lymphocyte responses. 
  • Peripheral nerve repair with collagen conduits. 
  • Pharmacokinetics of methanol and formate in female cynomolgus monkeys exposed to methanol vapors. 
  • Physiological organization of layer 4 in macaque striate cortex. 
  • Prevention of hyperacute xenograft rejection by intravenous immunoglobulin. 
  • Prevention trumps treatment of antibody-mediated transplant rejection. 
  • Proceedings of the 2022 National Toxicology Program Satellite Symposium. 
  • Progestin-induced apoptosis in the Macaque ovarian epithelium: differential regulation of transforming growth factor-beta. 
  • Protection from pathogenic SIV challenge using multigenic DNA vaccines. 
  • Protective immunity to SIV challenge elicited by vaccination of macaques with multigenic DNA vaccines producing virus-like particles. 
  • Rabbit antithymocyte globulin induction and sirolimus monotherapy supports prolonged islet allograft function in a nonhuman primate islet transplantation model. 
  • Regression of atherosclerosis in monkeys reduces vascular superoxide levels. 
  • Restricted expression of WT1 messenger ribonucleic acid in immature ovarian follicles: uniformity in mammalian and avian species and maintenance during reproductive senescence. 
  • Selected Resources for Pathology Evaluation of Nonhuman Primates in Nonclinical Safety Assessment. 
  • Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines. 
  • Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177). 
  • Species differences in natural xenoantibody to swine. 
  • Stimulus onset quenches neural variability: a widespread cortical phenomenon. 
  • Studies of human and monkey "epileptic" neocortex in the in vitro slice preparation. 
  • Superior Efficacy of a Human Immunodeficiency Virus Vaccine Combined with Antiretroviral Prevention in Simian-Human Immunodeficiency Virus-Challenged Nonhuman Primates. 
  • Synthesis and evaluation of compounds that facilitate the gastrointestinal absorption of heparin. 
  • Synthesis of C3 heteroatom-substituted azetidinones that display potent cholesterol absorption inhibitory activity. 
  • Temporal resolution of single-photon responses in primate rod photoreceptors and limits imposed by cellular noise. 
  • The Kety-Schmidt technique for quantitative perfusion and oxygen metabolism measurements in the MR imaging environment. 
  • The contribution of Fc effector mechanisms in the efficacy of anti-CD154 immunotherapy depends on the nature of the immune challenge. 
  • The influence of masseter and temporalis sarcomere length operating ranges as determined by laser diffraction on architectural estimates of muscle force and excursion in macaques (Macaca fascicularis and Macaca mulatta). 
  • The neural representation of speed in macaque area MT/V5. 
  • The orientation selectivity of color-responsive neurons in macaque V1. 
  • The physiologic consequences of vas ligation. 
  • The spatial transformation of color in the primary visual cortex of the macaque monkey. 
  • The use of a urinary estrone conjugates assay for detection of optimal mating time in the cynomolgus macaque (Macaca fascicularis). 
  • Topological analysis of population activity in visual cortex. 
  • Total lymphoid irradiation for cardiac xenotransplantation in nonhuman primates. 
  • Toxocara antigen and mitogen-induced lymphocyte blastogenesis for diagnosis of visceral larva migrans: clinical and experimental findings in macaques and human beings. 
  • Tuning for spatiotemporal frequency and speed in directionally selective neurons of macaque striate cortex. 
  • Uniform signal redundancy of parasol and midget ganglion cells in primate retina. 
  • Visual cortical signals supporting smooth pursuit eye movements. 
  • Visual motion analysis for pursuit eye movements in area MT of macaque monkeys. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology