Maleimides
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Subject Areas on Research
- Activation of PKC isoform beta(I) at the blood-brain barrier rapidly decreases P-glycoprotein activity and enhances drug delivery to the brain.
- Activation of extracellular signal-regulated kinase (ERK) in G2 phase delays mitotic entry through p21CIP1.
- Active involvement of PKC for insulin-mediated rates of muscle protein synthesis in Zucker rats.
- An explant technique for high-resolution imaging and manipulation of mycobacterial granulomas.
- Binding and signaling of surface-immobilized reagentless fluorescent biosensors derived from periplasmic binding proteins.
- Characterization of sulfhydryl groups on chloroplast coupling factor 1 exposed by heat activation.
- Chemical modification and fluorescence studies of chloroplast coupling factor.
- Controlling the kinetics of thiol-maleimide Michael-type addition gelation kinetics for the generation of homogenous poly (ethylene glycol) hydrogels
- Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.
- Fluorescence energy transfer measurements in the pyruvate dehydrogenase multienzyme complex from Escherichia coli with chemically modified lipoic acid.
- Fluorescence studies of the pyruvate dehydrogenase multienzyme complex from Escherichia coli.
- Fluorescent derivatives of the pyruvate dehydrogenase component of the Escherichia coli pyruvate dehydrogenase complex.
- Inhibiting Glycogen Synthase Kinase-3 Mitigates the Hematopoietic Acute Radiation Syndrome in a Sex- and Strain-dependent Manner in Mice.
- Inhibiting glycogen synthase kinase-3 mitigates the hematopoietic acute radiation syndrome in mice.
- Maleimide-Functionalized Poly(2-Oxazoline)s and Their Conjugation to Elastin-Like Polypeptides.
- Optogenetic photochemical control of designer K+ channels in mammalian neurons.
- Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes.
- Protein kinase C mediates potentiation of synaptic transmission by phorbol ester at parallel fibers in the dorsal cochlear nucleus.
- Protein kinase CK2 phosphorylates the cell cycle regulatory protein Geminin.
- Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells.
- Role of phospholipase Cbeta3 phosphorylation in the desensitization of cellular responses to platelet-activating factor.
- Ruboxistaurin, a protein kinase C beta inhibitor, as an emerging treatment for diabetes microvascular complications.
- Ruboxistaurin.
- Scaffold Hopping and Optimization of Maleimide Based Porcupine Inhibitors.
- Serine phosphorylation of glutathione S-transferase P1 (GSTP1) by PKCα enhances GSTP1-dependent cisplatin metabolism and resistance in human glioma cells.
- Site-specific conjugation of a temperature-sensitive polymer to a genetically-engineered protein.
- Spinal activation of protein kinase C elicits phrenic motor facilitation.
- Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2.
- Structural mapping of chloroplast coupling factor.
- Structural optimization of a "smart" doxorubicin-polypeptide conjugate for thermally targeted delivery to solid tumors.
- Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro.
- Synthesis and characterization of a ruthenium(II)-based redox conjugate for reagentless biosensing.
- Targeting breast carcinoma with radioiodinated anti-HER2 Nanobody.
- The C-terminus of the thromboxane receptor contributes to coupling and desensitization in a mouse mesangial cell line.
- The role of protein kinase C in modulation of aqueous humor outflow facility.
- VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases.