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Subject Areas on Research
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29 mammalian genomes reveal novel exaptations of mobile elements for likely regulatory functions in the human genome.
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A Roadmap to Heart Regeneration Through Conserved Mechanisms in Zebrafish and Mammals.
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A Scalable, Multiplexed Assay for Decoding GPCR-Ligand Interactions with RNA Sequencing.
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A comparative study of crosslinked and noncrosslinked fibrin from the major classes of vertebrates.
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A high-resolution map of human evolutionary constraint using 29 mammals.
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A mathematical model of circadian rhythms and dopamine.
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A new duck genome reveals conserved and convergently evolved chromosome architectures of birds and mammals.
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A preliminary analysis of correlated evolution in Mammalian chewing motor patterns.
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A preliminary analysis of correlations between chewing motor patterns and mandibular morphology across mammals.
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A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins.
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A radiation of arboreal basal eutherian mammals beginning in the Late Cretaceous of India.
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A timecourse analysis of systemic and gonadal effects of temperature on sexual development of the red-eared slider turtle Trachemys scripta elegans.
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Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals.
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Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation.
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Allergic response to medical products in patients with alpha-gal syndrome.
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Allometric scaling of metabolic rate and cardiorespiratory variables in aquatic and terrestrial mammals.
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An integrated encyclopedia of DNA elements in the human genome.
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An invertebrate model of the developmental neurotoxicity of insecticides: effects of chlorpyrifos and dieldrin in sea urchin embryos and larvae.
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Analysis of Cdc6 function in the assembly of mammalian prereplication complexes.
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Ancient transposable elements transformed the uterine regulatory landscape and transcriptome during the evolution of mammalian pregnancy.
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Ant Olfaction: Smells Like an Insect, Develops Like a Mammal.
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Antifungal effects of cyclosporine and FK 506 are mediated via immunophilin-dependent calcineurin inhibition.
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Apoptotic cell death in disease-Current understanding of the NCCD 2023.
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Architectural pattern, tissue and cellular morphology in livers of fishes: relationship to experimentally-induced neoplastic responses.
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Asynchronous axonal firing patterns evoked via continuous subthreshold kilohertz stimulation.
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Attempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africa.
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Baby Genomics: Tracing the Evolutionary Changes That Gave Rise to Placentation.
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Backbone and sidechain 1H, 15N and 13C resonance assignments of the free and RNA-bound tandem zinc finger domain of the tristetraprolin family member from Selaginella moellendorffii.
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Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway.
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Balancing acts: molecular control of mammalian iron metabolism.
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Behavioural and physiological limits to vision in mammals.
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Best practices for germ-free derivation and gnotobiotic zebrafish husbandry.
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Biased precursor ingression underlies the center-to-pole pattern of male sex determination in mouse.
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Biomechanics of mammalian feeding and primate evolution
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Body Mass and Tail Girth Predict Hibernation Expression in Captive Dwarf Lemurs.
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Bone-associated gene evolution and the origin of flight in birds.
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C. elegans as a model to study glial development.
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Capturing the primordial Kras mutation initiating urethane carcinogenesis.
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Cardiorespiratory coupling in cetaceans; a physiological strategy to improve gas exchange?
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Carolina critters: a collection of camera-trap data from wildlife surveys across North Carolina.
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Cell fate commitment during mammalian sex determination.
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Cell type- and species-specific host responses to Toxoplasma gondii and its near relatives.
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Cell-Cycle Regulators and Cell Death in Immunity.
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Cellular plasticity: 1712 to the present day.
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Cellular response to endoplasmic reticulum stress: a matter of life or death.
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Centromeres of human chromosomes.
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Characterization and expression of a rice RAD23 gene.
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Characterizing the phylogenetic specialism-generalism spectrum of mammal parasites.
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China's endemic vertebrates sheltering under the protective umbrella of the giant panda.
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Cilia proteins are biomarkers of altered flow in the vasculature.
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Cloning of a cDNA encoding bovine erythropoietin and analysis of its transcription in selected tissues.
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Cloning of human and mouse brain cDNAs coding for S1, the second member of the mammalian elongation factor-1 alpha gene family: analysis of a possible evolutionary pathway.
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Comparative Analysis of Protein Folding Stability-Based Profiling Methods for Characterization of Biological Phenotypes.
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Comparative Genomic Analysis of the Pheromone Receptor Class 1 Family (V1R) Reveals Extreme Complexity in Mouse Lemurs (Genus, Microcebus) and a Chromosomal Hotspot across Mammals.
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Comparative anatomy and phylogenetic distribution of the mammalian cecal appendix.
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Comparative genomics of mammalian hibernators using gene networks.
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Comparing effectiveness of experimental and implemented bycatch reduction measures: the ideal and the real.
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Concentration-Dependent Recruitment of Mammalian Odorant Receptors.
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Conservation: forest fragments, facts, and fallacies.
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Conserved microRNA program as key to mammalian cardiac regeneration: insights from zebrafish.
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Craniodental and humeral morphology of a new species of Masrasector (Teratodontinae, Hyaenodonta, Placentalia) from the late Eocene of Egypt and locomotor diversity in hyaenodonts.
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Cryo-EM reveals the architecture of the PELP1-WDR18 molecular scaffold.
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DNA replication origins-where do we begin?
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DNA replication.
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Deadly diving? Physiological and behavioural management of decompression stress in diving mammals.
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Deconstructing mammalian thermoregulation.
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Deep diving mammals: Dive behavior and circulatory adjustments contribute to bends avoidance.
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Deep-tissue SWIR imaging using rationally designed small red-shifted near-infrared fluorescent protein.
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Defining origins of replication in mammalian cells.
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Discs of mammalian rod photoreceptors form through the membrane evagination mechanism.
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Divergent projections from locus coeruleus to the corticobasal ganglia system and ventral tegmental area of the adult male zebra finch.
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Divergent regulation of protein synthesis in the cytosol and endoplasmic reticulum compartments of mammalian cells.
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Do animals living in larger groups experience greater parasitism? A meta-analysis.
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Dynamic evolution of the alpha (α) and beta (β) keratins has accompanied integument diversification and the adaptation of birds into novel lifestyles.
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Earliest record of Platychoerops (Primates, Plesiadapidae), a new species from Mouras Quarry, Mont de Berru, France.
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Effect of urban habitat use on parasitism in mammals: a meta-analysis.
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Effects of body size on estimation of mammalian area requirements.
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Effects of land use, habitat characteristics, and small mammal community composition on Leptospira prevalence in northeast Madagascar.
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Effects of stochastic sodium channels on extracellular excitation of myelinated nerve fibers.
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Endangered species hold clues to human evolution.
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Energetic cost of locomotion in animals.
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Epithelial/mesenchymal interactions and branching morphogenesis of the lung.
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Estimating parasite host range.
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Eukaryotic Sexual Reproduction Evoked "with a Little Help from My Friends".
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Evaluating and enhancing ribozyme reaction efficiency in mammalian cells.
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Evidence for a single loss of mineralized teeth in the common avian ancestor.
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Evidence for a tradeoff between retention time and chewing efficiency in large mammalian herbivores.
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Evidence for nutrient-dependent regulation of the COPII coat by O-GlcNAcylation.
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Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates.
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Evolution and development of the mammalian dentition: insights from the marsupial Monodelphis domestica.
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Evolution of fungal sex chromosomes.
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Evolution. Fossils versus clocks.
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Excision repair is required for genotoxin-induced mutagenesis in mammalian cells.
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Expanding the test set: Chemicals with potential to disrupt mammalian brain development.
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Experimental determination of rates of concerted evolution.
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Expression of heterogeneous nuclear ribonucleoprotein A2/B1 changes with critical stages of mammalian lung development.
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Expression, purification, and in vitro assays of mitochondrial single-stranded DNA-binding protein.
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Faunal assemblage composition and paleoenvironment of Plovers Lake, a Middle Stone Age locality in Gauteng Province, South Africa.
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Fibers in smaller fascicles have lower activation thresholds with cuff electrodes due to thinner perineurium and smaller cross-sectional area.
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Flow cytometric analysis of DNA content in budding yeast.
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Fueling the flames: Mammalian programmed necrosis in inflammatory diseases.
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Functional analysis of a mammalian odorant receptor subfamily.
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Functional and evolutionary aspects of axial stability in euarchontans and other mammals.
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Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae.
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Fusome topology and inheritance during insect gametogenesis.
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Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine.
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G protein-coupled receptor kinases.
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GABAergic signaling beyond synapses: an emerging target for cancer therapy.
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Gene Expression Profiling in the Hibernating Primate, Cheirogaleus Medius.
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Genetic approaches to access cell types in mammalian nervous systems.
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Genetic variance in fitness indicates rapid contemporary adaptive evolution in wild animals.
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Getting to the heart of regeneration in zebrafish.
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Global Mammal Parasite Database version 2.0.
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Global patterns of marine mammal, seabird, and sea turtle bycatch reveal taxa-specific and cumulative megafauna hotspots.
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Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota.
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Great ranging associated with greater reproductive investment in mammals.
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Have gene knockouts caused evolutionary reversals in the mammalian first arch?
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Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo.
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Host longevity and parasite species richness in mammals.
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Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.
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Hot Spot Mutagenesis Improves the Functional Expression of Unique Mammalian Odorant Receptors.
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How mammalian predation contributes to tropical tree community structure.
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How to protect half of Earth to ensure it protects sufficient biodiversity.
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Human dectin-1 deficiency and mucocutaneous fungal infections.
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Identification and characterization of two Ca2+/CaM-dependent protein kinases required for normal nuclear division in Aspergillus nidulans.
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Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers.
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Increased grassland arthropod production with mammalian herbivory and eutrophication: a test of mediation pathways.
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Infectious diseases and extinction risk in wild mammals.
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Inhibition of p53 Sulfoconjugation Prevents Oxidative Hepatotoxicity and Acute Liver Failure.
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Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii.
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Inter-stride variability triggers gait transitions in mammals and birds.
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Interactions among key residues regulate mammalian odorant receptor trafficking.
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Intrinsic activity of human immunodeficiency virus type 1 protease heterologous fusion proteins in mammalian cells.
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Intrinsic hand proportions of euarchontans and other mammals: implications for the locomotor behavior of plesiadapiforms.
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Intronic cis-regulatory modules mediate tissue-specific and microbial control of angptl4/fiaf transcription.
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Involvement of the HERV-derived cell-fusion inhibitor, suppressyn, in the fusion defects characteristic of the trisomy 21 placenta.
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Joint angular excursions during cyclical behaviors differ between tetrapod feeding and locomotor systems.
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Leadership in Mammalian Societies: Emergence, Distribution, Power, and Payoff.
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Lifting baselines to address the consequences of conservation success.
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Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast.
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Lung Regeneration: Cells, Models, and Mechanisms.
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MESH1 knockdown triggers proliferation arrest through TAZ repression.
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Male-mediated prenatal loss: Functions and mechanisms.
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Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast.
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Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
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Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans.
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Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators.
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Mammalian and Drosophila blood: JAK of all trades?
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Mammalian intestinal allometry, phylogeny, trophic level and climate.
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Mammalian molar complexity follows simple, predictable patterns.
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Mammalian odorant receptors: functional evolution and variation.
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Mammalian sexual differentiation: lessons from the spotted hyena.
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Mammals and rainfall: paleoecology of the middle Miocene at La Venta (Colombia, South America).
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Measurement of 25-hydroxyvitamin D 1-alpha-hydroxylase activity in mammalian kidney.
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Mechanisms of inbreeding avoidance in a wild primate.
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Mechanisms of protein prenylation and role in G protein function.
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Megafauna and ecosystem function from the Pleistocene to the Anthropocene.
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Microbial nitrogen limitation in the mammalian large intestine.
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Microparasites and Placental Invasiveness in Eutherian Mammals.
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Microvesicle release from inner segments of healthy photoreceptors is a conserved phenomenon in mammalian species.
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Missense mutation (G480C) in the CFTR gene associated with protein mislocalization but normal chloride channel activity.
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Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis.
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Modeling the excitability of mammalian nerve fibers: influence of afterpotentials on the recovery cycle.
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Modulation of Xenogeneic T-cell Proliferation by B7 and mTOR Blockade of T Cells and Porcine Endothelial Cells.
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Molecular Clocks without Rocks: New Solutions for Old Problems.
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Molecular insights into mechanisms of iron transport.
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Molecular phylogeny of the kinesin family of microtubule motor proteins.
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Morphometric characteristics of cells in the alveolar region of mammalian lungs.
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Moving in the Anthropocene: Global reductions in terrestrial mammalian movements.
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Mutualism or parasitism? Using a phylogenetic approach to characterize the oxpecker-ungulate relationship.
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Network calisthenics: control of E2F dynamics in cell cycle entry.
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New bedfellows in the mammalian sex-determination affair.
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New postcrania of Deccanolestes from the Late Cretaceous of India and their bearing on the evolutionary and biogeographic history of euarchontan mammals.
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Non-human primates avoid the detrimental effects of prenatal androgen exposure in mixed-sex litters: combined demographic, behavioral, and genetic analyses.
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Nucleotide sequences of the RNA subunit of RNase P from several mammals.
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Odorant receptors and desensitization proteins colocalize in mammalian sperm.
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On sexual dimorphism in immune function.
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Ongoing electrical activity of superior cervical ganglion cells in mammals of different size.
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Ontogenetic changes to metacarpal trabecular bone structure in mountain and western lowland gorillas.
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Organ protective mechanisms common to extremes of physiology: a window through hibernation biology.
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Organization of the superior olivary complex in the guinea pig. I. Cytoarchitecture, cytochrome oxidase histochemistry, and dendritic morphology.
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Origin of bistability underlying mammalian cell cycle entry.
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Overview of FEED, the feeding experiments end-user database.
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Oxidative stress in toxicology: established mammalian and emerging piscine model systems.
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Oxygen dissociation curve of echidna blood.
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PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
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Parasite resistance and the adaptive significance of sleep.
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Patterns and consequences of age-linked change in local relatedness in animal societies.
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Phosphorylated MED1 links transcription recycling and cancer growth.
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Phosphorylation of 4E-BP1 in the mammalian brain is not altered by LRRK2 expression or pathogenic mutations.
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Phylogenetic analysis of the ecology and evolution of mammalian sleep.
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Phylogenetic analysis of vertebrate lactate dehydrogenase (LDH) multigene families.
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Pioneering paradigms and magnificent manifestos--Leigh Van Valen's priceless contributions to evolutionary biology.
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Platypus and echidna genomes reveal mammalian biology and evolution.
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Polypeptides of endogenous avian C-type viruses: their detection in the plasma membrane of normal and infected cells.
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Primate origins, human origins, and the end of higher taxa.
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Programmable synthetic biomolecular condensates for cellular control.
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Protein kinases that phosphorylate activated G protein-coupled receptors.
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Protein serine/threonine phosphatases--new avenues for cell regulation.
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Pulmonary ventilation-perfusion mismatch: a novel hypothesis for how diving vertebrates may avoid the bends.
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RNA regulons: coordination of post-transcriptional events.
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RNA-responsive elements for eukaryotic translational control.
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RNPS1 inhibits excessive tumor necrosis factor/tumor necrosis factor receptor signaling to support hematopoiesis in mice.
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RTP family members induce functional expression of mammalian odorant receptors.
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Random Wiring, Ganglion Cell Mosaics, and the Functional Architecture of the Visual Cortex.
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Regulation of overexpressed hexokinases in liver and islet cells.
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Regulation of the cell cycle by calcium and calmodulin.
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Remotely Sensed Data Informs Red List Evaluations and Conservation Priorities in Southeast Asia.
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Reproductive inequality in humans and other mammals.
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Reversible protein phosphorylation regulates circadian rhythms.
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Rivers, blood and transportation networks.
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Role of TRPV ion channels in sensory transduction of osmotic stimuli in mammals.
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Scaling and mechanics of carnivoran footpads reveal the principles of footpad design.
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Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival.
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Selective microstimulation of central nervous system neurons.
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Sensitivity analysis of a model of mammalian neural membrane.
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Sequence coevolution and structure stabilization modulate olfactory receptor expression.
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Sequence heterochrony and the evolution of development.
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Sequences flanking the pentanucleotide T-antigen binding sites in the polyomavirus core origin help determine selectivity of DNA replication.
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Sex steroid hormone synthesis, metabolism, and the effects on the mammalian olfactory system.
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Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins.
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Single origin of Malagasy Carnivora from an African ancestor.
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SnapShot: Mammalian Sirtuins.
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Social determinants of health and survival in humans and other animals.
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Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology.
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Staying alive: cell death in antiviral immunity.
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Strand-specific mismatch repair in mammalian cells.
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Structural determinants for signal sequence function in the mammalian endoplasmic reticulum.
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Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus.
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Structures of yeast vesicle trafficking proteins.
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Suilloid fungi as global drivers of pine invasions.
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Sustaining the variety of life.
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TOR kinase homologs function in a signal transduction pathway that is conserved from yeast to mammals.
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Tapered Polymer Whiskers to Enable Three-Dimensional Tactile Feature Extraction.
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Tempo of trophic evolution and its impact on mammalian diversification.
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The Aryl Hydrocarbon Receptor: A Mediator and Potential Therapeutic Target for Ocular and Non-Ocular Neurodegenerative Diseases.
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The DVR gene family in embryonic development.
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The Ephrin B2 Receptor Tyrosine Kinase Is a Regulator of Proto-oncogene MYC and Molecular Programs Central to Barrett's Neoplasia.
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The Marine Mammal Protection Act at 40: status, recovery, and future of U.S. marine mammals.
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The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase.
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The Signaling Pathways Project, an integrated 'omics knowledgebase for mammalian cellular signaling pathways.
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The TGF-beta-related DVR gene family in mammalian development.
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The battle of the sexes.
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The battle of the sexes: opposing pathways in sex determination.
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The consensus mechanics of cultured mammalian cells
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The endothelial cell protein C receptor. Cell surface expression and direct ligand binding by the soluble receptor.
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The genome of the green anole lizard and a comparative analysis with birds and mammals.
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The largest and earliest known sample of dental caries in an extinct mammal (Mammalia, Euarchonta, Microsyops latidens) and its ecological implications.
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The molecular regulation of iron metabolism.
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The neurobiology of innate, volitional and learned vocalizations in mammals and birds.
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The oral ferroportin inhibitor vamifeport improves hemodynamics in a mouse model of sickle cell disease.
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The origin of helping: the role of variability in reproductive potential.
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The perception of transparent three-dimensional objects.
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The role of Sry in cellular events underlying mammalian sex determination.
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The sea urchin embryo as a model for mammalian developmental neurotoxicity: ontogenesis of the high-affinity choline transporter and its role in cholinergic trophic activity.
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The shrinking ark: patterns of large mammal extinctions in India.
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Theme and variations: heterothermy in mammals.
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Total energy expenditure of bottlenose dolphins (Tursiops truncatus) of different ages.
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Tracheal compression delays alveolar collapse during deep diving in marine mammals.
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Trans-Seq maps a selective mammalian retinotectal synapse instructed by Nephronectin.
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Transient transfection and purification of SARS-CoV-2 spike protein from mammalian cells.
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Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor.
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Type III protein secretion mechanism in mammalian and plant pathogens.
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Uncertainty in allometric exponent estimation: a case study in scaling metabolic rate with body mass.
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Uncovering the dynamics of a circadian-dopamine model influenced by the light-dark cycle.
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Uniqueness of primate forelimb posture during quadrupedal locomotion.
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Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals.
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Urolithin A attenuates severity of chronic pancreatitis associated with continued alcohol intake by inhibiting PI3K/AKT/mTOR signaling.
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Use of protein phosphatase inhibitors.
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Use of recombinant adenovirus for metabolic engineering of mammalian cells.
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Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
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Using noisy gene expression mediated by engineered adenovirus to probe signaling dynamics in mammalian cells.
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Variability in energy expenditure is much greater in males than females.
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Variation in gut microbiome structure across the annual hibernation cycle in a wild primate.
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Visual Signals in the Mammalian Auditory System.
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lambda RNA internal standards quantify sensitivity and amplification efficiency of mammalian gene expression profiling.
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Keywords of People
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Hirschey, Matthew,
Associate Professor of Medicine,
Cell Biology
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Hogan, Brigid L. M.,
Research Professor of Cell Biology,
Cell Biology
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Kay, Richard Frederick,
Professor of Evolutionary Anthropology,
Earth and Climate Sciences
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Reddy, Timothy E,
Associate Professor of Biostatistics & Bioinformatics,,
Molecular Genetics and Microbiology
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Yoder, Anne Daphne,
Braxton Craven Distinguished Professor of Evolutionary Biology,
Duke Science & Society