Marine Toxins

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  Subject Areas on Research

  • A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. 
  • Brevetoxin-6 (PbTx-6), a nonaromatic marine neurotoxin, is a ligand of the aryl hydrocarbon receptor. 
  • Casein kinase I in the mammalian circadian clock. 
  • Chiral action at a distance: remote substituent effects on the optical activity of calyculins A and B. 
  • Current concepts fish and shellfish poisoning. 
  • Dephosphorylation of ezrin as an early event in renal microvillar breakdown and anoxic injury. 
  • EF1A1-actin interactions alter mRNA stability to determine differential osteopontin expression in HepG2 and Hep3B cells. 
  • Effects of in vitro brevetoxin exposure on apoptosis and cellular metabolism in a leukemic T cell line (Jurkat). 
  • Eicosanoids in corals and crustaceans: primary metabolites that function as allelochemicals and pheromones. 
  • Electrophysiological and biochemical characteristics of Gymnodinium breve toxins. 
  • Foodborne disease outbreaks of chemical etiology in the United States, 1970-1974. 
  • From genome-wide to candidate gene: an investigation of variation at the major histocompatibility complex in common bottlenose dolphins exposed to harmful algal blooms. 
  • Genomewide investigation of adaptation to harmful algal blooms in common bottlenose dolphins (Tursiops truncatus). 
  • Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. 
  • Human health effects of exposure to Pfiesteria piscicida: a review. 
  • Human visual function in the North Carolina clinical study on possible estuary-associated syndrome. 
  • Inhibition of barnacle larval settlement and crustacean toxicity of some hoplonemertine pyridyl alkaloids. 
  • Inhibitor-1 interaction domain that mediates the inhibition of protein phosphatase-1. 
  • Lack of variation in voltage-gated sodium channels of common bottlenose dolphins (Tursiops truncatus) exposed to neurotoxic algal blooms. 
  • Life history responses of Daphnia similoides simultaneously exposed to microcystin-LR and ammonia and their postexposure recovery. 
  • Microcystin-LR, a potent protein phosphatase inhibitor, prolongs the serotonin- and cAMP-induced currents in sensory neurons of Aplysia californica. 
  • Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint. 
  • Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton. 
  • Optical signatures of molecular dissymmetry: combining theory with experiments to address stereochemical puzzles. 
  • Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets. 
  • Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus. 
  • Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis. 
  • Protein phosphatases mediate depotentiation induced by high-intensity theta-burst stimulation. 
  • Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle. 
  • Simultaneous stretching and contraction of stress fibers in vivo. 
  • Sodium channel activation augments NMDA receptor function and promotes neurite outgrowth in immature cerebrocortical neurons. 
  • Suppression of water-bloom cyanobacterium Microcystis aeruginosa by algaecide hydrogen peroxide maximized through programmed cell death. 
  • The role of protein kinase C in laminin-mediated neurite outgrowth. 
  • Use of protein phosphatase inhibitors. 
  • Use of protein phosphatase inhibitors. 
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  Keywords of People

  • Osterberg, Joshua Samuel, Adjunct Assistant Professor in the Marine Science and Conservation Division, Marine Science and Conservation