Gas Chromatography-Mass Spectrometry
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Subject Areas on Research
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2,4-Dienoyl-coenzyme A reductase deficiency: a possible new disorder of fatty acid oxidation.
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3-Hydroxyisovalerylcarnitine in 3-methylcrotonyl-CoA carboxylase deficiency.
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3-Hydroxyisovalerylcarnitine in patients with deficiency of 3-methylcrotonyl CoA carboxylase.
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3-hydroxy-3-methylglutaric aciduria presenting with Reye like syndrome: report of one case.
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A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma.
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A laboratory batch reactor test for assessing nonspeciated volatile organic compound biodegradation in activated sludge.
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A mass spectrometry-based proteomic approach to study Marek's Disease Virus gene expression.
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A non-invasive method for in vivo skin volatile compounds sampling.
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Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects.
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Alterations in brain glucose utilization accompanying elevations in blood ethanol and acetate concentrations in the rat.
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Alternate and new brominated flame retardants detected in U.S. house dust.
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An analysis of the duration of fentanyl and its metabolites in urine and saliva.
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An inner membrane dioxygenase that generates the 2-hydroxymyristate moiety of Salmonella lipid A.
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Analysis of abnormal urinary metabolites in the newborn period in medium-chain acyl-CoA dehydrogenase deficiency.
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Analysis of volatile free fatty acids in human urine by capillary column gas chromatography/mass spectrometry.
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Application of fast atom bombardment with tandem mass spectrometry and liquid chromatography/mass spectrometry to the analysis of acylcarnitines in human urine, blood, and tissue.
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Ascaris suum, an intestinal parasite, produces morphine.
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Associations between serum levels of polybrominated diphenyl ether (PBDE) flame retardants and environmental and behavioral factors in pregnant women.
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CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance.
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CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization, and potential functional significance.
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Carrier-free 131I-meta-iodobenzylguanidine: comparison of production from meta-diazobenzylguanidine and from meta-trimethylsilylbenzylguanidine.
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Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD.
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Characterization of new diagnostic acylcarnitines in patients with beta-ketothiolase deficiency and glutaric aciduria type I using mass spectrometry.
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Chemical composition of scent marks in the ringtailed lemur (Lemur catta): glandular differences, seasonal variation, and individual signatures.
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Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer's disease from normal cognitive aging.
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Comparison of GC-MS and GC×GC-MS in the analysis of human serum samples for biomarker discovery.
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Compounds from silicones alter enzyme activity in curing barnacle glue and model enzymes.
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Detection of endocrine disrupting chemicals in samples of second trimester human amniotic fluid.
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Detection of phytoestrogens in samples of second trimester human amniotic fluid.
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Determination of HBCD, PBDEs and MeO-BDEs in California sea lions (Zalophus californianus) stranded between 1993 and 2003.
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Determination of hormonal steroid concentrations in biological extracts by high resolution mass fragmentography.
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Development and characterization of a GC-enabled QLT-Orbitrap for high-resolution and high-mass accuracy GC/MS.
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Diagnostic and therapeutic implications of medium-chain acylcarnitines in the medium-chain acyl-coA dehydrogenase deficiency.
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Differential activation of human neutrophil cytosolic phospholipase A2 and secretory phospholipase A2 during priming by 1,2-diacyl- and 1-O-alkyl-2-acylglycerols.
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Differential volatile signatures from skin, naevi and melanoma: a novel approach to detect a pathological process.
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Effect of bimatoprost on intraocular pressure in prostaglandin FP receptor knockout mice.
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Effect-Directed Analysis of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) Ligands in Indoor Dust.
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Elevated levels of diesel range organic compounds in groundwater near Marcellus gas operations are derived from surface activities.
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Epidemiological marker for oxidant status: comparison of the ELISA and the gas chromatography/mass spectrometry assay for urine 2,3-dinor-5,6-dihydro-15-F2t-isoprostane.
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Escherichia coli produces linoleic acid during late stationary phase.
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Ethylmalonic aciduria: an organic acidemia with CNS involvement and vasculopathy.
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Eulemur, me lemur: the evolution of scent-signal complexity in a primate clade.
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Evaluating daily exposure to polychlorinated biphenyls and polybrominated diphenyl ethers in fish oil supplements.
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Exploratory investigation of biomarker candidates for suicide in schizophrenia and bipolar disorder.
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Exposure to PBDEs in the office environment: evaluating the relationships between dust, handwipes, and serum.
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Exposure to flame retardant chemicals on commercial airplanes.
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Flavored e-cigarette liquids reduce proliferation and viability in the CALU3 airway epithelial cell line.
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Glutathione species and metabolomic prints in subjects with liver disease as biological markers for the detection of hepatocellular carcinoma.
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Hexabromonaphthalene contaminants of polybrominated biphenyls: chemical composition and disposition in the rat.
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Homocysteine and retinal emboli: the Blue Mountains Eye Study.
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Identification of 3-methylglutarylcarnitine. A new diagnostic metabolite of 3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency.
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Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance.
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Identification of flame retardants in polyurethane foam collected from baby products.
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Identification of n-hydroxy acid metabolites in electron impact ionization mass spectrometry.
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In vitro metabolism of the brominated flame retardants 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (TBB) and bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate (TBPH) in human and rat tissues.
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In vitro synthesis of steroids by a feminising adrenocortical carcinoma: effect of prolactin and other protein hormones.
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Interrelations between C4 ketogenesis, C5 ketogenesis, and anaplerosis in the perfused rat liver.
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Isolation and insecticidal/anthelmintic activity of xanthonol, a novel bis-xanthone, from a non-sporulating fungal species.
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Isotope-dilution assay for urinary methylmalonic acid in the diagnosis of vitamin B12 deficiency. A prospective clinical evaluation.
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Isotopomer enrichment assay for very short chain fatty acids and its metabolic applications.
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Ligatin: a peripheral membrane protein with covalently bound palmitic acid.
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Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows.
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Measurement of prostaglandin production by isolated tissues and cells in culture.
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Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth.
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Metabolism of polybrominated diphenyl ethers (PBDEs) by human hepatocytes in vitro.
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Metabolomics Identifies a Biomarker Revealing In Vivo Loss of Functional β-Cell Mass Before Diabetes Onset.
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Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery.
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Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment.
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Mixture model normalization for non-targeted gas chromatography/mass spectrometry metabolomics data.
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Modular isotopomer synthesis of γ-hydroxybutyric acid for a quantitative analysis of metabolic fates.
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Neuroactive steroids are altered in schizophrenia and bipolar disorder: relevance to pathophysiology and therapeutics.
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Neuroactive steroids, mood stabilizers, and neuroplasticity: alterations following lithium and changes in Bcl-2 knockout mice.
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Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001.
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New techniques in quantitative mass spectrometry.
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Night and day: the comparative study of strepsirrhine primates reveals socioecological and phylogenetic patterns in olfactory signals.
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Nontarget Screening with High Resolution Mass Spectrometry in the Environment: Ready to Go?
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Novel and high volume use flame retardants in US couches reflective of the 2005 PentaBDE phase out.
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Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: implications for therapeutic actions.
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Oxidative stress, oxidative balance score, and hypertension among a racially diverse population.
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PBDEs, methoxylated PBDEs and HBCDs in Japanese common squid (Todarodes pacificus) from Korean offshore waters.
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Pathogenesis of acute and delayed corneal lesions after ocular exposure to sulfur mustard vapor.
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Pharmacodynamics of morphine-induced neuronal nitric oxide production and antinociceptive tolerance development.
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Pharmacokinetics of 619C89, a novel neuronal sodium channel inhibitor, in acute stroke patients after loading and discrete maintenance infusions.
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Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo.
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Pharmacometabolomic signature of ataxia SCA1 mouse model and lithium effects.
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Pharmacometabolomics of statin response.
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Phosphatidylcholine Biosynthesis in Mitis Group Streptococci via Host Metabolite Scavenging.
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Phthalates in baby skin care products.
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Polybrominated diphenyl ethers in house dust and clothes dryer lint.
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Polycyclic aromatic hydrocarbons in the atmospheres of Titan and Jupiter.
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Preliminary studies of 6 beta-hydroxydexamethasone and its importance in the DST.
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Preparation of antibodies and development of an enzyme immunoassay for determination of atrazine in environmental samples.
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Prevalence of Helicobacter pylori infection and associated factors among adults in Southern Brazil: a population-based cross-sectional study.
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Quantification of creatine and guanidinoacetate using GC-MS and LC-MS/MS for the detection of cerebral creatine deficiency syndromes.
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Reaction products of aquatic humic substances with chlorine.
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Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women.
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S-nitrosothiol repletion by an inhaled gas regulates pulmonary function.
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Short-chain acyl-coenzyme A dehydrogenase deficiency in mice.
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Significance of bound glutarate in the diagnosis of glutaric aciduria type I.
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Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum.
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Smelling right: the scent of male lemurs advertises genetic quality and relatedness.
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Social odours covary with bacterial community in the anal secretions of wild meerkats.
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Spatial distribution of bottlenose dolphins (Tursiops truncatus) inferred from stable isotopes and priority organic pollutants.
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Stable-isotope dilution GC-MS for determination of toluene in submilliliter volumes of whole blood.
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Stereospecificity of monoacylglycerol acyltransferase activity from rat intestine and suckling rat liver.
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Temporal variability in (13)C of respired CO(2) in a pine and a hardwood forest subject to similar climatic conditions.
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The impact of exercise training compared to caloric restriction on hepatic and peripheral insulin resistance in obesity.
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The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease.
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The neurotoxin quinolinic acid is increased in spinal cords of mice with herpes simplex virus encephalitis.
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The reaction of methionine with hydroxyl radical: reactive intermediates and methanethiol production.
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The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present.
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Transforming growth factor beta induced protein accumulation in granular corneal dystrophy type III (Reis-Bücklers dystrophy). Identification by mass spectrometry in 15 year old two-dimensional protein gels.
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Ultraviolet photolysis of chlorpyrifos: developmental neurotoxicity modeled in PC12 cells.
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Untargeted metabolomics analysis of ischemia-reperfusion-injured hearts ex vivo from sedentary and exercise-trained rats.
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Urinalysis of atrazine exposure in farm pesticide applicators.
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Keywords of People
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Bradford, Daniel William,
Associate Professor of Psychiatry and Behavioral Sciences,
Psychiatry & Behavioral Sciences, Social and Community Psychiatry
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Ferguson, P. Lee,
Associate Professor of Civil and Environmental Engineering,
Civil and Environmental Engineering
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Guan, Ziqiang,
Research Professor in Biochemistry,
Biochemistry