Maternal-Fetal Exchange

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  Subject Areas on Research

  • A critical period for the role of thyroid hormone in development of renal alpha-adrenergic receptors. 
  • A physiologic model of the dehydroepiandrosterone to estrogen conversion system in the fetoplacental unit. I. Development. 
  • A physiologic model of the dehydroepiandrosterone to estrogen conversion system in the fetoplacental unit. II. Preliminary clinical application--the dehydroepiandrosterone loading test. 
  • A six-month-old boy with neonatal lupus and cardiac enlargement. 
  • Accelerated development of immunity following transplantation of maternal marrow stem cells into infants with severe combined immunodeficiency and transplacentally acquired lymphoid chimerism. 
  • Acute effects of cocaine on ornithine decarboxylase activity in fetal and neonatal rat heart: evidence for cardiotoxicity. 
  • Androgens and masculinization of genitalia in the spotted hyaena (Crocuta crocuta). 2. Effects of prenatal anti-androgens. 
  • Behavioral effects of chronic exposure to low concentrations of halothane during development in rats. 
  • Beta-2 adrenergic control of ornithine decarboxylase activity in brain regions of the developing rat. 
  • Biochemical development of the rat lung: studies on cellular DNA, RNA and protein content in relation to maternal vitamin A status. 
  • Bisphenol A exposure alters developmental gene expression in the fetal rhesus macaque uterus. 
  • Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs. 
  • Chimerism in children with juvenile dermatomyositis. 
  • Chimerism in myositis. 
  • Choline-induced spatial memory facilitation correlates with altered distribution and morphology of septal neurons. 
  • Clear-cell adenocarcinoma of the vagina and cervix in girls: analysis of 170 registry cases. 
  • Clear-cell adenocarcinoma of the vagina and cervix in young females: analysis of 37 tumors that persisted or recurred after primary therapy. 
  • Complications of prenatal therapy with diethylstilbestrol. 
  • Critical review: nicotine for the fetus, the infant and the adolescent? 
  • Cytology of clear-cell adenocarcinoma of genital tract in young females: review of 95 cases from the registry. 
  • Deficits in development of central cholinergic pathways caused by fetal nicotine exposure: differential effects on choline acetyltransferase activity and [3H]hemicholinium-3 binding. 
  • Development of [3H]nicotine binding sites in brain regions of rats exposed to nicotine prenatally via maternal injections or infusions. 
  • Development of central and peripheral catecholaminergic systems in rats addicted perinatally to methadone. 
  • Developmental pattern of the hepatic DNA, RNA and protein in relation to maternal vitamin A status in rats. 
  • Diabetes in pregnancy. 
  • Differential effects of placental lactogen, growth hormone and prolactin on rat liver ornithine decarboxylase activity in the perinatal period. 
  • Dose-dependent effect of prenatal dexamethasone treatment on beta-adrenergic receptor coupling to ornithine decarboxylase and cyclic AMP. 
  • Dose-dependent glucocorticoid effects on noradrenergic synaptogenesis in rat brain: ontogeny of [3H]desmethylimipramine binding sites after fetal exposure to dexamethasone. 
  • Dysplasia and cytologic findings in 4,589 young women enrolled in diethylstilbestrol-adenosis (DESAD) project. 
  • Early biochemical detection of adverse effects of a neurobehavioral teratogen: influence of prenatal methylmercury exposure on ornithine decarboxylase in brain and other tissues of fetal and neonatal rat. 
  • Editor's Highlight: Transplacental and Lactational Transfer of Firemaster® 550 Components in Dosed Wistar Rats. 
  • Editorial: Viral Infection at the Maternal-Fetal Interface. 
  • Effect of maternal ethanol ingestion on neonatal rat brain and heart ornithine decarboxylase. 
  • Effects of late prenatal or early postnatal ethanol exposure on ornithine decarboxylase activity in brain and heart of developing rats. 
  • Effects of maternal ethanol ingestion on amine uptake into synaptosomes of fetal and neonatal rat brain. 
  • Effects of maternal methadone administration on ornithine decarboxylase in brain and heart of the offspring: relationships of enzyme activity to dose and to growth impairment in the rat. 
  • Effects of perinatal PCB exposure on discrimination-reversal learning in monkeys. 
  • Effects of prenatal dexamethasone or terbutaline exposure on development of neural and intrinsic control of heart rate. 
  • Effects of prenatal nicotine exposure on biochemical development of rat brain regions: maternal drug infusions via osmotic minipumps. 
  • Elevated frequencies of micronucleated erythrocytes in infants exposed to zidovudine in utero and postpartum to prevent mother-to-child transmission of HIV. 
  • Emerging roles for lysophospholipid mediators in pregnancy. 
  • Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates. 
  • Exposure to naturally circulating androgens during foetal life incurs direct reproductive costs in female spotted hyenas, but is prerequisite for male mating. 
  • Expression and trafficking of placental microRNAs at the feto-maternal interface. 
  • Expression of membrane-bound HLA-G at the maternal-fetal interface is not associated with pregnancy maintenance among patients with idiopathic recurrent pregnancy loss. 
  • Facial features of infants exposed prenatally to cocaine. 
  • Fetal dexamethasone exposure impairs cellular development in neonatal rat heart and kidney: effects on DNA and protein in whole tissues. 
  • Fetal dexamethasone exposure interferes with establishment of cardiac noradrenergic innervation and sympathetic activity. 
  • Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE. 
  • Fetal nicotine exposure ablates the ability of postnatal nicotine challenge to release norepinephrine from rat brain regions. 
  • Fetal translocation and metabolism of PAH obtained from coal fly ash given intratracheally to pregnant rats. 
  • GPER1 is required to protect fetal health from maternal inflammation. 
  • Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke. 
  • Gestational exposure to chlorpyrifos: comparative distribution of trichloropyridinol in the fetus and dam. 
  • Gestational exposure to chlorpyrifos: dose response profiles for cholinesterase and carboxylesterase activity. 
  • Glucocorticoids accelerate the ontogenetic transition of cardiac ventricular myosin heavy-chain isoform expression in the rat: promotion by prenatal exposure to a low dose of dexamethasone. 
  • Glucocorticoids regulate the development of intracellular signaling: enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure. 
  • HLA-G and HLA-C at the feto-maternal interface: lessons learned from pathogenic viruses. 
  • Histochemical analyses of altered fetal lung development following single vs multiple courses of antenatal steroids. 
  • Human leukocyte antigen matching and fetal loss: results of a 10 year prospective study. 
  • IVIG therapy in neonatal isoimmune thrombocytopenic purpura and alloimmunization thrombocytopenia. 
  • Imidacloprid induces neurobehavioral deficits and increases expression of glial fibrillary acidic protein in the motor cortex and hippocampus in offspring rats following in utero exposure. 
  • Inability of gestational hormones to account for the inhibitory effects of pregnancy plasmas on lymphocyte responses in vitro. 
  • Independent variation and positive selection in env V1 and V2 domains within maternal-infant strains of human immunodeficiency virus type 1 in vivo. 
  • Intravillous eicosanoid compartmentalization and regulation of placental blood flow. 
  • Introduction to sex differences in neurotoxic effects. 
  • Kindling, prenatal exposure to ethanol and postnatal development selectively alter responses of hippocampal pyramidal cells to NMDA. 
  • Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission. 
  • Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero. 
  • Maternal autoantibody levels in congenital heart block and potential prophylaxis with antiinflammatory agents. 
  • Maternal exposure to particulate matter increases postnatal ozone-induced airway hyperreactivity in juvenile mice. 
  • Maternal hemodynamic monitoring and the Vigileo monitor. 
  • Maternal methadone administration: deficit in development of alpha-noradrenergic responses in developing rat brain as assessed by norepinephrine stimulation of 33Pi incorporation into phospholipids in vivo. 
  • Maternal vitamin A restriction alters biochemical development of the brain in rats. 
  • Maturation of the adrenal medulla--IV. Effects of morphine. 
  • Metabolism and distribution of norethynodrel in pregnant and nonpregnant mice. 
  • Microchimerism in children with rheumatic disorders: what does it mean? 
  • Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination. 
  • Neonatal alloimmune thrombocytopenic purpura. 
  • Neonatal experimental autoimmune myasthenia gravis. 
  • Neural tube defects and herbal medicines containing lead: a possible relationship. 
  • Perinatal effects of drugs of abuse. 
  • Perinatal methadone addiction affects brain synaptic development of biogenic amine systems in the rat. 
  • Pharmacologic studies in vulnerable populations: Using the pediatric experience. 
  • Phase I evaluation of zidovudine administered to infants exposed at birth to the human immunodeficiency virus. 
  • Phosphatidic acid phosphatase in neonatal rat lung: effects of prenatal dexamethasone or terbutaline treatment on basal activity and on responsiveness to beta adrenergic stimulation. 
  • Physiopathologic role of cubilin and megalin. 
  • Placental Transfer of Respiratory Syncytial Virus Antibody Among HIV-Exposed, Uninfected Infants. 
  • Placental hormones and the control of maternal metabolism and fetal growth. 
  • Placental transfer and fetal distribution of 3H-retinoic acid in rats. 
  • Placental transfer of metals of coal fly ash into various fetal organs of rat. 
  • Placental transport of free palmitic and linoleic acids in the guinea pig. 
  • Polydrug-using adolescent mothers and their infants receiving early intervention. 
  • Postnatal alterations in beta-adrenergic receptor binding in rat brain regions after continuous prenatal exposure to propranolol via maternal infusion. 
  • Postnatal distribution of vitamin A in liver, lung, heart and brain of the rat in relation to maternal vitamin A status. 
  • Precocious development of sympatho-adrenal function in rats whose mothers received methadone. 
  • Pregnancy and rheumatoid arthritis: insights into the immunology of fetal tolerance and control of autoimmunity. 
  • Prenatal carbon monoxide and adult evoked potentials in rats. 
  • Prenatal cocaine and cell development in rat brain regions: effects on ornithine decarboxylase and macromolecules. 
  • Prenatal dexamethasone administration disrupts the pattern of cellular development in rat lung. 
  • Prenatal dexamethasone exposure causes loss of neonatal hypoxia tolerance: cellular mechanisms. 
  • Prenatal diethylstilbestrol exposure and cancer risk in women. 
  • Prenatal diethylstilbestrol exposure and human genital tract abnormalities. 
  • Prenatal exposure to nicotine via maternal infusions: effects on development of catecholamine systems. 
  • Prenatal exposure to propranolol via continuous maternal infusion: effects on physiological and biochemical processes mediated by beta adrenergic receptors in fetal and neonatal rat lung. 
  • Prenatal maternal biochemistry predicts neonatal biochemistry. 
  • Prenatal nicotine exposure impairs beta-adrenergic function: persistent chronotropic subsensitivity despite recovery from deficits in receptor binding. 
  • Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to beta-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure. 
  • Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to beta-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure. 
  • Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies. 
  • Radiologic Aspects of the Diagnosis of Pulmonary Embolism in Pregnancy. 
  • Reduction in oocyte number following prenatal exposure to a diet high in galactose. 
  • Regulation of fetal cardiac and hepatic beta-adrenoceptors and adenylyl cyclase signaling: terbutaline effects. 
  • Report of the WHO technical consultation on the effect of maternal influenza and influenza vaccination on the developing fetus: Montreal, Canada, September 30-October 1, 2015. 
  • Seasonality, sociality, and reproduction: Long-term stressors of ring-tailed lemurs (Lemur catta). 
  • Serum immunogbulin cocentrations during normal pregnancy. 
  • Side effects of oral misoprostol for the prevention of postpartum hemorrhage: results of a community-based randomised controlled trial in rural India. 
  • Spontaneous elevation in arterial blood pressure during the first hours of life in the very-low-birth-weight infant. 
  • Sympatho-adrenal development in perinatally addicted rats. 
  • Systemic lupus erythematosus and pregnancy outcomes: an update and review of the literature. 
  • Temperature-activated ion channels in neural crest cells confer maternal fever-associated birth defects. 
  • The Role of Congenital Cytomegalovirus Infection in Adverse Birth Outcomes: A Review of the Potential Mechanisms. 
  • The effect of pre- or postnatal lead exposure on Hamilton Search Task in monkeys. 
  • The effects of high-dose toluene on embryonic development in the rat. 
  • The fetal allograft revisited: does the study of an ancient invertebrate species shed light on the role of natural killer cells at the maternal-fetal interface? 
  • The roles of DNA methylation of NR3C1 and 11β-HSD2 and exposure to maternal mood disorder in utero on newborn neurobehavior. 
  • Thyroid hormone regulates ontogeny of beta adrenergic receptors and adenylate cyclase in rat heart and kidney: effects of propylthiouracil-induced perinatal hypothyroidism. 
  • Transdermal nicotine replacement in pregnancy: maternal pharmacokinetics and fetal effects. 
  • Ultrasound diagnosis of fetal anomalies associated with in utero cocaine exposure: further support for cocaine-induced vascular disruption teratogenesis. 
  • Vaginal and cervical abnormalities, including clear-cell adenocarcinoma, related to prenatal exposure to stilbestrol. 
  • Vaginal epithelial changes in young women enrolled in the National Cooperative Diethylstilbestrol Adenosis (DESAD) project. 
  • Varicella in a susceptible pregnant woman. 
  • Vitamin A supply and biochemical development of the rat heart: studies on cellular DNA, RNA and protein. 
  • Why certain antibodies cross-react with HLA-A and HLA-G: epitope mapping of two common MHC class I reagents. 
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  Keywords of People

  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology