Meiosis

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  Subject Areas on Research

  • A High-Resolution Map of Meiotic Recombination in Cryptococcus deneoformans Demonstrates Decreased Recombination in Unisexual Reproduction. 
  • A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern. 
  • A microtubule-destabilizing kinesin motor regulates spindle length and anchoring in oocytes. 
  • A new method for the cytological analysis of autoantibody specificities using whole-mount, surface-spread meiotic nuclei. 
  • A novel meiotic drive locus almost completely distorts segregation in mimulus (monkeyflower) hybrids. 
  • A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast. 
  • A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest. 
  • Across the meiotic divide - CSF activity in the post-Emi2/XErp1 era. 
  • Allelic and ectopic interactions in recombination-defective yeast strains. 
  • Allelic and ectopic recombination between Ty elements in yeast. 
  • Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae. 
  • Analysis of centromeric activity in Robertsonian translocations: implications for a functional acrocentric hierarchy. 
  • Analysis of meiotic recombination events near a recombination hotspot in the yeast Saccharomyces cerevisiae. 
  • Analysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae. 
  • Anastral spindle assembly and γ-tubulin in Drosophila oocytes. 
  • Anastral spindle assembly: a mathematical model. 
  • Asexual reproduction in a close relative of Arabidopsis: a genetic investigation of apomixis in Boechera (Brassicaceae). 
  • Assembly and dynamics of an anastral:astral spindle: the meiosis II spindle of Drosophila oocytes. 
  • Assembly pathway of the anastral Drosophila oocyte meiosis I spindle. 
  • Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity. 
  • Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition. 
  • Cell-type-dependent histone demethylase specificity promotes meiotic chromosome condensation in Arabidopsis. 
  • Checkpoint signals in grasshopper meiosis are sensitive to microtubule attachment, but tension is still essential. 
  • Chromatin conformation of yeast centromeres 
  • Chromosomal translocations generated by high-frequency meiotic recombination between repeated yeast genes. 
  • Chromosome distribution, molecular motors and the claret protein. 
  • Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. 
  • Context dependence of meiotic recombination hotspots in yeast: the relationship between recombination activity of a reporter construct and base composition. 
  • Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. 
  • Control of meiotic recombination and gene expression in yeast by a simple repetitive DNA sequence that excludes nucleosomes. 
  • Convergent evolution of linked mating-type loci in basidiomycete fungi. 
  • Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae. 
  • Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiae. 
  • DNA mismatch repair and genetic instability. 
  • DNA-binding protein RAP1 stimulates meiotic recombination at the HIS4 locus in yeast. 
  • Decreased meiotic intergenic recombination and increased meiosis I nondisjunction in exo1 mutants of Saccharomyces cerevisiae. 
  • Development and characterization of a genetic linkage map of Cryptococcus neoformans var. neoformans using amplified fragment length polymorphisms and other markers. 
  • Disruption of mitotic arrest precedes precocious differentiation and transdifferentiation of pregranulosa cells in the perinatal Wnt4 mutant ovary. 
  • Disruption of testis cords by cyclopamine or forskolin reveals independent cellular pathways in testis organogenesis. 
  • Dynamic genome plasticity during unisexual reproduction in the human fungal pathogen Cryptococcus deneoformans. 
  • Effects of Temperature on the Meiotic Recombination Landscape of the Yeast Saccharomyces cerevisiae. 
  • Efficient sporulation of yeast in media buffered near pH6. 
  • Enhancement of the ncdD microtubule motor mutant by mutants of alpha Tub67C. 
  • Evidence that myosin does not contribute to force production in chromosome movement. 
  • Evolution of pathogenicity and sexual reproduction in eight Candida genomes. 
  • Evolution of the segregation ratio: modification of gene conversion and meiotic drive. 
  • Expanded Satellite Repeats Amplify a Discrete CENP-A Nucleosome Assembly Site on Chromosomes that Drive in Female Meiosis. 
  • Factors enforcing the species boundary between the human pathogens Cryptococcus neoformans and Cryptococcus deneoformans. 
  • Fine-scale variation in meiotic recombination in Mimulus inferred from population shotgun sequencing. 
  • Fine-structure mapping of meiosis-specific double-strand DNA breaks at a recombination hotspot associated with an insertion of telomeric sequences upstream of the HIS4 locus in yeast. 
  • Functional epialleles at an endogenous human centromere. 
  • Fungal genome and mating system transitions facilitated by chromosomal translocations involving intercentromeric recombination. 
  • GFP fusions to a microtubule motor protein to visualize meiotic and mitotic spindle dynamics in Drosophila. 
  • Gene conversion occurs within the mating-type locus of Cryptococcus neoformans during sexual reproduction. 
  • Gene expression in oogenesis and implications for transgenerational effects of environmental toxicants. 
  • Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae. 
  • Genetic and genomic evolution of sexual reproduction: echoes from LECA to the fungal kingdom. 
  • Genetic circuits that govern bisexual and unisexual reproduction in Cryptococcus neoformans. 
  • Genetic control of chromosome length in yeast. 
  • Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break. 
  • Genetics. Origin of species in overdrive. 
  • Genomic and functional variation of human centromeres. 
  • Global analysis of the relationship between the binding of the Bas1p transcription factor and meiosis-specific double-strand DNA breaks in Saccharomyces cerevisiae. 
  • Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae. 
  • Heterochronic meiotic misexpression in an interspecific yeast hybrid. 
  • High-frequency meiotic gene conversion between repeated genes on nonhomologous chromosomes in yeast. 
  • High-resolution genome-wide analysis of irradiated (UV and γ-rays) diploid yeast cells reveals a high frequency of genomic loss of heterozygosity (LOH) events. 
  • How cells get the right chromosomes. 
  • Increased expression of estrogen receptor beta in pachytene spermatocytes after short-term methoxyacetic acid administration. 
  • Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus). 
  • Interplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosis. 
  • Intrachromosomal gene conversion in yeast. 
  • Kinesins at a glance. 
  • Kinetochore rearrangement in meiosis II requires attachment to the spindle. 
  • Linkage localization of X-linked Charcot-Marie-Tooth disease. 
  • Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast. 
  • Long-Chain Polyprenols Promote Spore Wall Formation in Saccharomyces cerevisiae. 
  • Loss of a histone deacetylase dramatically alters the genomic distribution of Spo11p-catalyzed DNA breaks in Saccharomyces cerevisiae. 
  • Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations. 
  • Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae. 
  • Mature Drosophila meiosis I spindles comprise microtubules of mixed polarity. 
  • Maximal stimulation of meiotic recombination by a yeast transcription factor requires the transcription activation domain and a DNA-binding domain. 
  • Measurements of excision repair tracts formed during meiotic recombination in Saccharomyces cerevisiae. 
  • Mechanistic plasticity of sexual reproduction and meiosis in the Candida pathogenic species complex. 
  • Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin. 
  • Meiosis, mitosis and microtubule motors. 
  • Meiosis-specific double-strand DNA breaks at the HIS4 recombination hot spot in the yeast Saccharomyces cerevisiae: control in cis and trans. 
  • Meiotic chromosome distribution in Drosophila oocytes: roles of two kinesin-related proteins. 
  • Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae. 
  • Meiotic crossing over between nonhomologous chromosomes affects chromosome segregation in yeast. 
  • Meiotic germ cells antagonize mesonephric cell migration and testis cord formation in mouse gonads. 
  • Meiotic recombination between dispersed repeated genes is associated with heteroduplex formation. 
  • Meiotic recombination between repeated transposable elements in Saccharomyces cerevisiae. 
  • Meiotic recombination hot spots and cold spots. 
  • Meiotic recombination involving heterozygous large insertions in Saccharomyces cerevisiae: formation and repair of large, unpaired DNA loops. 
  • Meiotic recombination within the centromere of a yeast chromosome. 
  • Meiotic sister chromatid recombination. 
  • Microbial genetics: Love the one you're with. 
  • Mitotic and meiotic gene conversion of Ty elements and other insertions in Saccharomyces cerevisiae. 
  • Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. 
  • Mutagenesis from meiotic recombination is not a primary driver of sequence divergence between Saccharomyces species. 
  • Mutant alleles of the meiotic locus, mei-9, differ in degree of effects on rod chromosome magnification and ring chromosome transmission in Drosophila. 
  • Mutants of the microtubule motor protein, nonclaret disjunctional, affect spindle structure and chromosome movement in meiosis and mitosis. 
  • N-terminal acetylation promotes synaptonemal complex assembly in C. elegans. 
  • Natural variation in CDC28 underlies morphological phenotypes in an environmental yeast isolate. 
  • Ncd motor binding and transport in the spindle. 
  • Nested Inversion Polymorphisms Predispose Chromosome 22q11.2 to Meiotic Rearrangements. 
  • On the origin of meiotic reproduction: a genetic modifier model. 
  • Origins of eukaryotic sexual reproduction. 
  • Palindromic sequences in heteroduplex DNA inhibit mismatch repair in yeast. 
  • Patterns of heteroduplex formation associated with the initiation of meiotic recombination in the yeast Saccharomyces cerevisiae. 
  • Physical detection of heteroduplexes during meiotic recombination in the yeast Saccharomyces cerevisiae. 
  • Physical lengths of meiotic and mitotic gene conversion tracts in Saccharomyces cerevisiae. 
  • Polarity of meiotic gene conversion in fungi: contrasting views. 
  • Polytenization of the ribosomal genes on the X and Y chromosomes of Drosophila melanogaster. 
  • Population dynamics of a meiotic/mitotic expansion model for the fragile X syndrome. 
  • Post-cytochrome C protection from apoptosis conferred by a MAPK pathway in Xenopus egg extracts. 
  • Properties of Mitotic and Meiotic Recombination in the Tandemly-Repeated CUP1 Gene Cluster in the Yeast Saccharomyces cerevisiae. 
  • Recombination hotspots flank the Cryptococcus mating-type locus: implications for the evolution of a fungal sex chromosome. 
  • Recombining without Hotspots: A Comprehensive Evolutionary Portrait of Recombination in Two Closely Related Species of Drosophila. 
  • Relationship between nuclease-hypersensitive sites and meiotic recombination hot spot activity at the HIS4 locus of Saccharomyces cerevisiae. 
  • Repair of DNA loops involves DNA-mismatch and nucleotide-excision repair proteins. 
  • Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae. 
  • Retinoic acid regulates sex-specific timing of meiotic initiation in mice. 
  • Ring chromosomes and rDNA magnification in Drosophila. 
  • Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast. 
  • SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. 
  • Selection and analysis of spontaneous reciprocal mitotic cross-overs in Saccharomyces cerevisiae. 
  • Separation of meiotic and mitotic effects of claret non-disjunctional on chromosome segregation in Drosophila. 
  • Seven-base-pair inverted repeats in DNA form stable hairpins in vivo in Saccharomyces cerevisiae. 
  • Sex-induced silencing operates during opposite-sex and unisexual reproduction in Cryptococcus neoformans. 
  • Sexual reproduction between partners of the same mating type in Cryptococcus neoformans. 
  • Shifting gears and putting on the brakes: Female germ cells transition into meiosis. 
  • Simple Mendelian inheritance of the repeating yeast ribosomal DNA genes. 
  • Spindle dynamics during meiosis in Drosophila oocytes. 
  • Ssk2 mitogen-activated protein kinase kinase kinase governs divergent patterns of the stress-activated Hog1 signaling pathway in Cryptococcus neoformans. 
  • Synaptonemal complex complement of man in spreads of spermatocytes, with details of the sex chromosome pair. 
  • TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse. 
  • The Drosophila claret segregation protein is a minus-end directed motor molecule. 
  • The Drosophila ncd microtubule motor protein is spindle-associated in meiotic and mitotic cells. 
  • The Golgi apparatus of rat pachytene spermatocytes during spermatogenesis. 
  • The Tn3 beta-lactamase gene acts as a hotspot for meiotic recombination in yeast. 
  • The claret locus in Drosophila encodes products required for eyecolor and for meiotic chromosome segregation. 
  • The compact chromatin structure of a Ty repeated sequence suppresses recombination hotspot activity in Saccharomyces cerevisiae. 
  • The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae. 
  • The role of meiotic drive in hybrid male sterility. 
  • The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast. 
  • Triplet repeats form secondary structures that escape DNA repair in yeast. 
  • Uncoupling of genomic and epigenetic signals in the maintenance and inheritance of heterochromatin domains in fission yeast. 
  • Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans. 
  • Unisexual reproduction drives meiotic recombination and phenotypic and karyotypic plasticity in Cryptococcus neoformans. 
  • Use of a CEPH meiotic breakpoint panel to refine the locus of limb-girdle muscular dystrophy type 1A (LGMD1A) to a 2-Mb interval on 5q31. 
  • Variation in Recombination Rate: Adaptive or Not? 
  • Vertebrate Reproduction. 
  • Whole-Genome and Segmental Homozygosity Confirm Errors in Meiosis as Etiology of Struma Ovarii. 
  • Wrestling with Chromosomes: The Roles of SUMO During Meiosis. 
  • β-importin Tnpo-SR promotes germline stem cell maintenance and oocyte differentiation in female Drosophila.