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Subject Areas on Research
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A CACNA1C variant associated with reduced voltage-dependent inactivation, increased CaV1.2 channel window current, and arrhythmogenesis.
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A calcium-activated, nonselective cationic conductance in Aplysia silent neurons.
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A charged residue in S4 regulates coupling among the activation gate, voltage, and Ca2+ sensors in BK channels.
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A circuit model for saccadic suppression in the superior colliculus.
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A comparison of chemical and electrical synaptic transmission between single sensory cells and a motoneurone in the central nervous system of the leech.
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A computer model of electrical stimulation of peripheral nerves in regional anesthesia.
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A mathematical model for persistent post-CSD vasoconstriction.
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A model of status epilepticus based on electrical stimulation of hippocampal afferent pathways.
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A mutation in the intracellular loop III/IV of mosquito sodium channel synergizes the effect of mutations in helix IIS6 on pyrethroid resistance.
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A negative charge in transmembrane segment 1 of domain II of the cockroach sodium channel is critical for channel gating and action of pyrethroid insecticides.
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A non-pungent resiniferatoxin analogue, phorbol 12-phenylacetate 13 acetate 20-homovanillate, reveals vanilloid receptor subtypes on rat trigeminal ganglion neurons.
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A novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias.
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A novel basal promoter element is required for expression of the rat tyrosine hydroxylase gene.
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A novel chloride channel in Vicia faba guard cell vacuoles activated by the serine/threonine kinase, CDPK.
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A novel role for primary cilia in airway remodeling.
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A novel, calcium-induced triphasic current response in silent, non-bursting Aplysia neurons.
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A numerical scheme for modeling wavefront propagation on a monolayer of arbitrary geometry.
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A prototype inverse solution in one-dimension to find the origin of excitation, strand radius, intracellular resistivity, or distance from the surface.
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A rapid capsaicin-activated current in rat trigeminal ganglion neurons.
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A residue in the transmembrane segment 6 of domain I in insect and mammalian sodium channels regulate differential sensitivities to pyrethroid insecticides.
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A role for TREK1 in generating the slow afterhyperpolarization in developing starburst amacrine cells.
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A source of bias in the analysis of single channel data: assessing the apparent interaction between channel proteins.
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A theoretical analysis of acute ischemia and infarction using ECG reconstruction on a 2-D model of myocardium.
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A voltage-gated calcium-selective channel encoded by a sodium channel-like gene.
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Ability of epinephrine, but not increased extracellular calcium, to reverse the effects of verapamil on ventricular automaticity in vitro.
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Abnormal neuronal excitability in hippocampal slices from kindled rats.
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Abscisic acid activation of plasma membrane Ca(2+) channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in abi1-1 and abi2-1 protein phosphatase 2C mutants.
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Acceleration of functional reentry by rapid pacing in anisotropic cardiac monolayers: formation of multi-wave functional reentries.
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Accessory subunit KChIP2 modulates the cardiac L-type calcium current.
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Activation during ventricular defibrillation in open-chest dogs. Evidence of complete cessation and regeneration of ventricular fibrillation after unsuccessful shocks.
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Activation of calcium channels by cAMP in STC-1 cells is dependent upon Ca2+ calmodulin-dependent protein kinase II.
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Activity-dependent expression of RNA binding protein HuD and its association with mRNAs in neurons.
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Adaptive Mesh Refinement and Adaptive Time Integration for Electrical Wave Propagation on the Purkinje System.
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Adrenergic CaV1.2 Activation via Rad Phosphorylation Converges at α1C I-II Loop.
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Age-dependent inhibition of long-term potentiation by ethanol in immature versus mature hippocampus.
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Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture.
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Altered cocaine potency in the nucleus accumbens following 7-day withdrawal from intermittent but not continuous treatment: voltammetric assessment of dopamine uptake in the rat.
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Altering integrin engagement regulates membrane localization of Kir2.1 channels.
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Aminopyridines and sparteine as inhibitors of membrane potassium conductance: effects on Myxicola giant axons and the lobster neuromuscular junction.
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An epilepsy/dyskinesia-associated mutation enhances BK channel activation by potentiating Ca2+ sensing.
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An important role of a pyrethroid-sensing residue F1519 in the action of the N-alkylamide insecticide BTG 502 on the cockroach sodium channel.
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An integrative model of mouse cardiac electrophysiology from cell to torso.
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Analytical model of extracellular potentials in a tissue slab with a finite bath.
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Analytical solution for time-dependent potentials in a fiber stimulated by an external electrode
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Antiarrhythmic drug action. Blockade of the inward sodium current.
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Antidromic propagation of action potentials in branched axons: implications for the mechanisms of action of deep brain stimulation.
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Antillatoxin, a novel lipopeptide, enhances neurite outgrowth in immature cerebrocortical neurons through activation of voltage-gated sodium channels.
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Aspects of rate-related hyperpolarization in feline Purkinje fibers.
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Asymmetrical electrically induced injury of rabbit ventricular myocytes.
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Asymptotic model of electrical stimulation of nerve fibers.
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Atomic distance estimates from disulfides and high-affinity metal-binding sites in a K+ channel pore.
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Auditory plasticity in a basal ganglia-forebrain pathway during decrystallization of adult birdsong.
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BDNF profoundly and specifically increases KCNQ4 expression in neurons derived from embryonic stem cells.
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Balanced synaptic impact via distance-dependent synapse distribution and complementary expression of AMPARs and NMDARs in hippocampal dendrites.
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Barbiturate enhancement of spike frequency adaptation in Aplysia giant neurons.
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Barbiturate-induced slow outward currents in Aplysia neurones.
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Basic concepts in cellular cardiac electrophysiology: Part I: Ion channels, membrane currents, and the action potential.
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Biochemical and biophysical identification of cystic fibrosis transmembrane conductance regulator chloride channels as components of endocytic clathrin-coated vesicles.
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Bioelectrorheological model of the cell. 5. Electrodestruction of cellular membrane in alternating electric field.
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Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells.
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Bipolar stimulation of a three-dimensional bidomain incorporating rotational anisotropy.
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Block of wild-type and inactivation-deficient cardiac sodium channels IFM/QQQ stably expressed in mammalian cells.
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Blockade of cardiac sodium channels. Competition between the permeant ion and antiarrhythmic drugs.
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Blockade of rabbit atrial sodium channels by lidocaine. Characterization of continuous and frequency-dependent blocking.
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Ca(v)3.1 splice variant expression during neuronal differentiation of Y-79 retinoblastoma cells.
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Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites.
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Calcium channel function regulated by the SH3-GK module in beta subunits.
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Calcium-activated inward spike after-currents in bursting neurone R15 of Aplysia.
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Capsaicin, acid and heat-evoked currents in rat trigeminal ganglion neurons: relationship to functional VR1 receptors.
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Capsaicin-induced currents with distinct desensitization and Ca2+ dependence in rat trigeminal ganglion cells.
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Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes.
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Cell penetration properties of maurocalcine, a natural venom peptide active on the intracellular ryanodine receptor.
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Cell size and communication: role in structural and electrical development and remodeling of the heart.
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Cellular and Synaptic Properties of Local Inhibitory Circuits.
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Cellular effects of deep brain stimulation: model-based analysis of activation and inhibition.
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Central opioid receptors mediate morphine-induced itch and chronic itch via disinhibition.
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Changes in osmolality sensitize the response to capsaicin in trigeminal sensory neurons.
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Changes in synaptic transmission produced by hydrogen peroxide.
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Characterization of ATP-sensitive potassium channels in intestinal, cholecystokinin-secreting cells.
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Characterization of concentration- and use-dependent effects of quinidine from conduction delay and declining conduction velocity in canine Purkinje fibers.
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Characterization of constitutive exocytosis in the yeast Saccharomyces cerevisiae.
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Characterization of excitatory amino acid receptors expressed by embryonic chick motoneurons in vitro.
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Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit.
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Characterization of the energy-dependent, mating factor-activated Ca2+ influx in Saccharomyces cerevisiae.
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Characterization of the hyperpolarization-activated chloride current in dissociated rat sympathetic neurons.
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Characterizing activity-dependent processes with a piecewise exponential model.
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Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2.
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Chronic IL-1beta signaling potentiates voltage-dependent sodium currents in trigeminal nociceptive neurons.
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Chronic cigarette smoke extract treatment selects for apoptotic dysfunction and mitochondrial mutations in minimally transformed oral keratinocytes.
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Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus.
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Cisplatin-induced changes in sodium, chloride, and urea transport by the frog skin.
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Comparative toxicity of kainic acid and other acidic amino acids toward rat hippocampal neurons.
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Control of electrical alternans in simulations of paced myocardium using extended time-delay autosynchronization.
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Correlation between axonal morphologies and synaptic input kinetics of interneurons from mouse visual cortex.
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Correlation between function and structure in "epileptic" human hippocampal tissue maintained in vitro.
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Coupled sodium-calcium transport in cultured chick heart cells.
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Cultivation in rotating bioreactors promotes maintenance of cardiac myocyte electrophysiology and molecular properties.
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Cultured porcine trabecular meshwork cells display altered lysosomal function when subjected to chronic oxidative stress.
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Current flow patterns in two-dimensional anisotropic bisyncytia with normal and extreme conductivities.
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Cyclic GMP modulates depletion-activated Ca2+ entry in pancreatic acinar cells.
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Cyclosporin A inhibits chromium(VI)-induced apoptosis and mitochondrial cytochrome c release and restores clonogenic survival in CHO cells.
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Cytoskeletal actin gates a Cl- channel in neocortical astrocytes.
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Daptomycin resistance in enterococci is associated with distinct alterations of cell membrane phospholipid content.
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Deep brain stimulation alleviates parkinsonian bradykinesia by regularizing pallidal activity.
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Defective glycolysis and calcium signaling underlie impaired insulin secretion in a transgenic mouse.
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Defective potassium currents in ataxia telangiectasia fibroblasts.
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Delineation of the signaling pathways involved in glucocorticoid-induced and spontaneous apoptosis of rat thymocytes.
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Dendritic properties of hippocampal CA1 pyramidal neurons in the rat: intracellular staining in vivo and in vitro.
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Depression of glutamate-mediated synaptic transmission by benzyl alcohol.
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Depression of sustained evoked potentials and glial depolarization in the spinal cord by barbiturates and by diphenylhydantoin.
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Design and implementation of a new computerized system for intraoperative cardiac mapping.
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Development of intrinsic and synaptic properties in a forebrain nucleus essential to avian song learning.
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Developmental differences in the sensitivity of spontaneous and miniature IPSCs to ethanol.
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Differential P1-purinergic modulation of human Schlemm's canal inner-wall cells.
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Differential abscisic acid regulation of guard cell slow anion channels in Arabidopsis wild-type and abi1 and abi2 mutants.
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Differential effects of TipE and a TipE-homologous protein on modulation of gating properties of sodium channels from Drosophila melanogaster.
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Differential effects of phenobarbital and pentobarbital on stimulus train-induced bursting in the hippocampal slice.
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Dispersion of latencies in photoreceptors of Limulus and the adapting-bump model.
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Distinct electric potentials in soma and neurite membranes.
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Diurnal changes in exocytosis and the number of synaptic ribbons at active zones of an ON-type bipolar cell terminal.
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Dopamine reduces slow outward current and calcium influx in burst-firing neuron R15 of Aplysia.
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Dual response of lobster muscle fibers to L-glutamate.
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Dual-wavelength ratiometric fluorescence measurement of the membrane dipole potential.
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Dynamics of networks of randomly connected excitatory and inhibitory spiking neurons.
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Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD.
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Dysregulation of mitochondrial bioenergetics and quality control by HIV-1 Tat in cardiomyocytes.
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Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
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Effect of amiloride and some of its analogues of cation transport in isolated frog skin and thin lipid membranes.
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Effect of cocaine and cocaine congeners on veratridine-induced depolarization in mouse cerebrocortical synaptoneurosomes.
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Effect of conductivity interfaces.
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Effect of junctional resistance on source-strength in a linear cable.
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Effect of microscopic and macroscopic discontinuities on the response of cardiac tissue to defibrillating (stimulating) currents.
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Effect of nerve growth factor on synaptic depression after axotomy.
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Effect of oxygen at high pressure on spontaneous transmitter release.
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Effective boundary conditions for syncytial tissues.
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Effects of chemical group specific reagents on sodium entry and the amiloride binding site in frog skin: evidence for separate sites.
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Effects of droperidol on depolarization-induced automaticity, maximum upstroke velocity (Vmax) and the kinetics of recovery of Vmax in guinea-pig ventricular myocardium.
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Effects of electroporation on the transmembrane potential distribution in a two-dimensional bidomain model of cardiac tissue.
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Effects of electroporation on transmembrane potential induced by defibrillation shocks.
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Effects of multiple metal binding sites on calcium and magnesium-dependent activation of BK channels.
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Effects of stimulation frequency on potassium activity and cell volume in cardiac tissue.
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Effects of volatile anesthetics on N-methyl-D-aspartate excitotoxicity in primary rat neuronal-glial cultures.
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Efficient fully implicit time integration methods for modeling cardiac dynamics.
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Electric field stimulation of excitable tissue.
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Electric field stimulation of excitable tissue.
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Electric fields within cells as a function of membrane resistivity--a model study.
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Electrical coupling mediates tunable low-frequency oscillations and resonance in the cerebellar Golgi cell network.
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Electrical stimulation directly induces pre-angiogenic responses in vascular endothelial cells by signaling through VEGF receptors.
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Electrode systems for measuring cardiac impedances using optical transmembrane potential sensors and interstitial electrodes--theoretical design.
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Electrophysiological correlates of secretion in normal human parathyroid cells.
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Electrophysiological effects of sulfinpyrazone on canine cardiac Purkinje fibers.
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Electrophysiology of reactive oxygen production in signaling endosomes.
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Electroporation and shock-induced transmembrane potential in a cardiac fiber during defibrillation strength shocks.
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Electrotonic loading of anisotropic cardiac monolayers by unexcitable cells depends on connexin type and expression level.
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Endothelin activates voltage-dependent Ca2+ current by a G protein-dependent mechanism in rabbit cardiac myocytes.
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Enhancement of transmission at the developing retinogeniculate synapse.
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Ethanol and magnesium ions inhibit N-methyl-D-aspartate-mediated synaptic potentials in an interactive manner.
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Ethanol diminishes a voltage-dependent K+ current, the M-current, in CA1 hippocampal pyramidal neurons in vitro.
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Ethanol inhibition of AMPA and kainate receptor-mediated depolarizations of hippocampal area CA1.
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Existence of both fast and slow channel activity during the early stages of ventricular fibrillation.
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Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1.
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Facilitation of the induction of long-term potentiation by GABAB receptors.
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Facilitatory effects of 4-aminopyridine on neuromuscular transmission in disease states.
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Facilitatory effects of 4-aminopyridine on normal neuromuscular transmission.
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Familial hypokalemic periodic paralysis.
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Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal.
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Field stimulation of 2-D sheets of excitable tissue.
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Field stimulation of cardiac fibers with random spatial structure.
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Field stimulation of cells in suspension: use of a hybrid finite element method.
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Field stimulation of isolated chick heart cells: comparison of experimental and theoretical activation thresholds.
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Firing frequency of leaky intergrate-and-fire neurons with synaptic current dynamics.
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From subthreshold to firing-rate resonance.
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Functional analysis of a mammalian odorant receptor subfamily.
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Functional asymmetry of transmembrane segments in nicotinic acetylcholine receptors.
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Functional selectivity of dopamine receptor agonists. II. Actions of dihydrexidine in D2L receptor-transfected MN9D cells and pituitary lactotrophs.
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G protein G(alpha)o is essential for vomeronasal function and aggressive behavior in mice.
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GABAB autoreceptors mediate activity-dependent disinhibition and enhance signal transmission in the dentate gyrus.
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GYGD pore motifs in neighbouring potassium channel subunits interact to determine ion selectivity.
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Genesis of QRS in the ruminant: graphic simulation.
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Genesis of the monophasic action potential: role of interstitial resistance and boundary gradients.
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Global forebrain dynamics predict rat behavioral states and their transitions.
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Glutamate as transmitter of hippocampal perforant path.
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Glycine antagonism does not block ischemic spontaneous depolarization in the rat.
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Growth factor erv1-like modulates Drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells.
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Haploinsufficiency in peptidylglycine alpha-amidating monooxygenase leads to altered synaptic transmission in the amygdala and impaired emotional responses.
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High ratio of synaptic excitation to synaptic inhibition in hilar ectopic granule cells of pilocarpine-treated rats.
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High-throughput cardiac safety evaluation and multi-parameter arrhythmia profiling of cardiomyocytes using microelectrode arrays.
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Highly selective water channel activity measured by voltage clamp: analysis of planar lipid bilayers reconstituted with purified AqpZ.
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Homogenization of syncytial tissues.
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How many channels should there be in a gap junction?
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Hybrid finite element method for describing the electrical response of biological cells to applied fields.
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Hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving TRPV1 but not TRPV4.
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Hypothermia reduces the propensity of cortical tissue to propagate direct current depolarizations in the rat.
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Identification of a binding motif in the S5 helix that confers cholesterol sensitivity to the TRPV1 ion channel.
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Identification of acetylcholine receptors in adult rat trigeminal ganglion neurons.
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Identification of the carotenoid present in the B-800-850 antenna complex from Rhodopseudomonas capsulata as that which responds electrochromically to transmembrane electric fields.
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Implication of mitochondrial involvement in apoptotic activity of fragile histidine triad gene: application of synchronous luminescence spectroscopy.
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In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease.
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In vitro modulation of endogenous rhythms by AC electric fields: Syncing with clinical brain stimulation.
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In vitro properties of neurons in the rat pretectal nucleus of the optic tract.
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Inclusion of junction elements in a linear cardiac model through secondary sources: application to defibrillation.
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Increased GABAergic function in mouse models of Huntington's disease: reversal by BDNF.
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Increased adhesion between neutral lipid bilayers: interbilayer bridges formed by tannic acid.
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Increased spontaneous unit activity and appearance of spontaneous negative potentials in the goldfish tectum during refinement of the optic projection.
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Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain-of-function variant.
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Influence of buffers on dV/dtmax recovery kinetics with lidocaine in myocardium.
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Innervation of sympathetic neurones in the guinea-pig thoracic chain.
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Interaction between TRPV1-expressing neurons in the hypothalamus.
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Interaction between residues in the Mg2+-binding site regulates BK channel activation.
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Interaction of anaesthetics with electrical synapses.
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Interactions between hypothermia and the latency to ischemic depolarization: implications for neuroprotection.
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Intercostal muscle biopsy studies in myasthenia gravis: clinical correlations and the direct effects of drugs and myasthenic serum.
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Interstitial potentials and their change with depth into cardiac tissue.
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Intracellular hemin is a potent inhibitor of the voltage-gated potassium channel Kv10.1.
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Intracellular magnesium does not antagonize calcium-dependent acetylcholine secretion.
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Inversion of the current-distance relationship by transient depolarization.
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Ion channel behavior of amphotericin B in sterol-free and cholesterol- or ergosterol-containing supported phosphatidylcholine bilayer model membranes investigated by electrochemistry and spectroscopy.
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Iron transport across biologic membranes.
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Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect?
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Ischemic modulation of vulnerable period and the effects of pharmacological treatment of ischemia-induced arrhythmias: a simulation study.
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Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells.
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Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling.
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K channel subconductance levels result from heteromeric pore conformations.
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Kinetics of interaction of disopyramide with the cardiac sodium channel: fast dissociation from open channels at normal rest potentials.
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Kinetics of interaction of the lidocaine metabolite glycylxylidide with the cardiac sodium channel. Additive blockade with lidocaine.
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LTP in the mouse nucleus accumbens is developmentally regulated.
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La3+ blockage of glutamate action at the lobster neuromuscular junction.
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Lability of the prolonged depolarizing afterpotential in Balanus photoreceptors.
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Late Na channels in cardiac cells: the physiological role of background Na channels.
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Ligand binding to transiently accessible sites: mechanisms for varying apparent binding rates.
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Limitations of approximate solutions for computing the extracellular potential of single fibers and bundle equivalents.
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Lipid solubility modulates pH potentiation of local anesthetic block of Vmax reactivation in guinea pig myocardium.
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Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1.
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Localized membrane depolarizations and localized calcium influx during electric field-guided neurite growth.
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Luminal CCK-releasing factor stimulates CCK release from human intestinal endocrine and STC-1 cells.
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Magnitude of the solvation pressure depends on dipole potential.
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Mapping the interaction surface of scorpion β-toxins with an insect sodium channel.
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Measuring Feedforward Inhibition and Its Impact on Local Circuit Function.
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Mechanism and specificity of lanthanide series cation transport by ionophores A23187, 4-BrA23187, and ionomycin.
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Mechanism of origin of conduction disturbances in aging human atrial bundles: experimental and model study.
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Mechanisms of closure of cardiac sodium channels in rabbit ventricular myocytes: single-channel analysis.
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Mechanisms of regulating the respiratory burst in leukocytes.
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Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics.
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Mechanisms regulating variability of the single photon responses of mammalian rod photoreceptors.
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Members of the myocyte enhancer factor 2 transcription factor family differentially regulate Bdnf transcription in response to neuronal depolarization.
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Membrane biophysical studies of lymphocytes and erythrocytes in manic-depressive illness.
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Membrane current from transmembrane potentials in complex core-conductor models
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Membrane potential mediates H(+)-ATPase dependence of "degradative pathway" endosomal fusion.
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Membrane properties underlying spontaneous activity of denervated muscle fibres.
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Metabolic inhibition-induced transient Ca2+ increase depends on mitochondria in a human proximal renal cell line.
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Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition.
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Microcystin-LR, a potent protein phosphatase inhibitor, prolongs the serotonin- and cAMP-induced currents in sensory neurons of Aplysia californica.
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Microfluidic dielectrophoresis illuminates the relationship between microbial cell envelope polarizability and electrochemical activity.
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Microprobe analysis of Tc-MIBI in heart cells: calculation of mitochondrial membrane potential.
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Microscopic variations in interstitial and intracellular structure modulate the distribution of conduction delays and block in cardiac tissue with source-load mismatch.
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MinK-dependent internalization of the IKs potassium channel.
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Mitochondria in apoptosis and human disease.
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Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues.
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Model of creation and evolution of stable electropores for DNA delivery.
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Modeling electroporation in a single cell.
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Modeling electroporation in a single cell. I. Effects Of field strength and rest potential.
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Modeling the effects of electric fields on nerve fibers: determination of excitation thresholds.
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Modelling induction of a rotor in cardiac muscle by perpendicular electric shocks.
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Modelling the periodicity of cardiac muscle.
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Modification of a cylindrical bidomain model for cardiac tissue.
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Modifications of the cardiac double-layer source arising from interstitial potentials.
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Modified cable equation incorporating transverse polarization of neuronal membranes for accurate coupling of electric fields.
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Modulation of IA currents by capsaicin in rat trigeminal ganglion neurons.
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Modulation of conduction velocity by nonmyocytes in the low coupling regime.
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Modulation of the binding of signal peptides to lipid bilayers by dipoles near the hydrocarbon-water interface.
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Modulation of the interbilayer hydration pressure by the addition of dipoles at the hydrocarbon/water interface.
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Molecular and functional characterization of a novel sodium channel TipE-like auxiliary subunit from the American cockroach Periplaneta americana.
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Molecular basis for species-specific sensitivity to "hot" chili peppers.
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Molecular characterization and functional expression of the DSC1 channel.
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Molecular dissection of gating in the ClC-2 chloride channel.
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Molecular endpoints of Ca2+/calmodulin- and voltage-dependent inactivation of Ca(v)1.3 channels.
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Molecular mechanisms of BK channel activation.
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Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A.
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Multiple roles for the active zone protein RIM1alpha in late stages of neurotransmitter release.
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Mystery of biphasic defibrillation waveform efficacy is it calcium?
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N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator.
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NADH fluorescence and [K+]o changes during hippocampal electrical stimulation.
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NMDA receptor antagonists disinhibit rat posterior cingulate and retrosplenial cortices: a potential mechanism of neurotoxicity.
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Negative resistance characteristic essential for the maintenance of slow oscillations in bursting neurons.
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Neonatal experimental autoimmune myasthenia gravis.
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Nerve terminal remodeling visualized in living mice by repeated examination of the same neuron.
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Neurokinin-1 receptor enhances TRPV1 activity in primary sensory neurons via PKCepsilon: a novel pathway for heat hyperalgesia.
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Neurosteroid modulation of GABAergic neurotransmission in the central amygdala: a role for NMDA receptors.
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Neurotrophin regulation of ionic currents and cell size depends on cell context.
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Newly identified brain potassium channels gated by the guanine nucleotide binding protein Go.
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Nicotine inhibits voltage-dependent sodium channels and sensitizes vanilloid receptors.
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Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle.
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Nitroxyl anion regulation of the NMDA receptor.
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Non-monotonic effects of GABAergic synaptic inputs on neuronal firing.
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Novel anisotropic engineered cardiac tissues: studies of electrical propagation.
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Novel hybrid action of GABA mediates inhibitory feedback in the mammalian retina.
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One-dimensional model of cardiac defibrillation.
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Ongoing electrical activity of superior cervical ganglion cells in mammals of different size.
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Open Na+ channel blockade: multiple rest states revealed by channel interactions with disopyramide and quinidine.
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Optical imaging of living brain slices.
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Optical mapping of translucence changes in rat hippocampal slices during hypoxia.
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Optical measurements of transmembrane potential changes during electric field stimulation of ventricular cells.
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Origin of epicardial ST-T wave potentials in the intact dog.
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Ouabain effects on intracellular potassium activity and contractile force in cat papillary muscle.
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Oxidative stress and adenine nucleotide control of mitochondrial permeability transition.
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Oxygen dependency of synaptic transmission at the squid Loligo pealei giant synapse.
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PH-Dependent effects of quinidine on the kinetics of dV/dtmax in guinea pig ventricular myocardium.
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Penicillin effects on iontophoretic responses in Aplysia californica.
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Periodic conductivity as a mechanism for cardiac stimulation and defibrillation.
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Peripheral axonal injury results in reduced mu opioid receptor pre- and post-synaptic action in the spinal cord.
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Persistence of prolonged light-induced conductance change in arthropod photoreceptors on recovery from anoxia.
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Phasic ion channel blockade. A kinetic model and parameter estimation procedure.
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Phosducin regulates the expression of transducin betagamma subunits in rod photoreceptors and does not contribute to phototransduction adaptation.
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Phosphorylation and nuclear translocation of a regulator of G protein signaling (RGS10).
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Plant cell-surface GIPC sphingolipids sense salt to trigger Ca2+
influx.
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Platelet glutathione transport: characteristics and evidence for regulation by intraplatelet thiol status.
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Polarization of a spherical cell in a nonuniform extracellular electric field.
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Polarized expression of cAMP-activated chloride channels in isolated epithelial cells.
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Pore region of TRPV3 ion channel is specifically required for heat activation.
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Post-natal reduction of neural unit size in the rabbit ciliary ganglion.
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Postischemic synaptic excitation and N-methyl-D-aspartate receptor activation in gerbils.
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Potential and current distributions in a cylindrical bundle of cardiac tissue.
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Potential distribution in three-dimensional periodic myocardium--Part I: Solution with two-scale asymptotic analysis.
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Potential distribution in three-dimensional periodic myocardium--Part II: Application to extracellular stimulation.
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Predicting patterns of epicardial potentials during ventricular fibrillation
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Prediction of myelinated nerve fiber stimulation thresholds: limitations of linear models.
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Primary blast injury causes cognitive impairments and hippocampal circuit alterations.
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Proconvulsant and anticonvulsant properties of ethanol: studies of electrographic seizures in vitro.
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Progenitor Hyperpolarization Regulates the Sequential Generation of Neuronal Subtypes in the Developing Neocortex.
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Progressive incorporation of propidium iodide in cultured mouse neurons correlates with declining electrophysiological status: a fluorescence scale of membrane integrity.
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Prolonged inhibition in burst firing neurons: synaptic inactivation of the slow regenerative inward current.
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Propagation of excitation in idealized anisotropic two-dimensional tissue.
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Propagation versus delayed activation during field stimulation of cardiac muscle.
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Properties of multivesicular release from mouse rod photoreceptors support transmission of single-photon responses.
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Protective role of transient pore openings in calcium handling by cardiac mitochondria.
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Protein phosphatases mediate depotentiation induced by high-intensity theta-burst stimulation.
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Purification and reconstitution of the calcium release channel from skeletal muscle.
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Re-innervation of ganglia transplanted to the neck from different levels of the guinea-pig sympathetic chain.
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Reception of microwaves by the brain.
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Recognition and processing of randomly fluctuating electric signals by Na,K-ATPase.
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Reduction of pentylenetetrazole-induced seizure activity in awake rats by seizure-triggered trigeminal nerve stimulation.
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Reduction of voltage-dependent currents by ethanol contributes to inhibition of NMDA receptor-mediated excitatory synaptic transmission.
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Reflection after delayed excitation in a computer model of a single fiber.
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Regulation of biliary secretion through apical purinergic receptors in cultured rat cholangiocytes.
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Regulation of cholecystokinin secretion by ATP-sensitive potassium channels.
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Regulation of membrane chloride currents in rat bile duct epithelial cells.
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Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors.
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Reproducing cardiac restitution properties using the Fenton-Karma membrane model.
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Response features of parvalbumin-expressing interneurons suggest precise roles for subtypes of inhibition in visual cortex.
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Response of a single cell to an external electric field.
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Retinal rod photoreceptor-specific gene mutation perturbs cone pathway development.
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Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties.
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Rod vision is controlled by dopamine-dependent sensitization of rod bipolar cells by GABA.
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Role of Na-K pump potassium regulation and IPSPs in seizures and spreading depression in immature rabbit hippocampal slices.
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Role of membrane curvature in mechanoelectrical transduction: ion carriers nonactin and valinomycin sense changes in integral bending energy.
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Role of the GLT-1 subtype of glutamate transporter in glutamate homeostasis: the GLT-1-preferring inhibitor WAY-855 produces marginal neurotoxicity in the rat hippocampus.
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Role of the sixth transmembrane segment of domain IV of the cockroach sodium channel in the action of sodium channel blocker insecticides.
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Schwan equation and transmembrane potential induced by alternating electric field.
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Sedative and GABAergic effects of ethanol on male and female rats.
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Seizure-like spreading depression in immature rabbit hippocampus in vitro.
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Sensory attributes of complex tasting divalent salts are mediated by TRPM5 and TRPV1 channels.
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Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels.
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Serotonin regulates dynamics of cerebellar granule cell activity by modulating tonic inhibition.
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Short-term effects of prednisolone on neuromuscular transmission in normal rats and those with experimental autoimmune myasthenia gravis.
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Similar propagation of SD and hypoxic SD-like depolarization in rat hippocampus recorded optically and electrically.
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Simple spike responses of gaze velocity Purkinje cells in the floccular lobe of the monkey during the onset and offset of pursuit eye movements.
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Simulation of propagation along a cylindrical bundle of cardiac tissue--I: Mathematical formulation.
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Simulation of propagation along a cylindrical bundle of cardiac tissue--II: Results of simulation.
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Single-detector simultaneous optical mapping of V(m) and [Ca(2+)](i) in cardiac monolayers.
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Slow sodium channel inactivation and use-dependent block modulated by the same domain IV S6 residue.
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Sodium channel activation augments NMDA receptor function and promotes neurite outgrowth in immature cerebrocortical neurons.
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Somatostatin augments the M-current in hippocampal neurons.
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Somatostatin immunohistochemistry of hippocampal slices with lucifer yellow-stained pyramidal neurons responding to somatostatin.
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Sonic hedgehog induces GLT-1 degradation via PKC delta to suppress its transporter activities.
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Spatial performance correlates with in vitro potentiation in young and aged Fischer 344 rats.
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Spatiotemporal properties of layer V neurons of the rat primary somatosensory cortex.
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Spontaneous cortical activity in awake monkeys composed of neuronal avalanches.
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Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx.
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Stimulus onset quenches neural variability: a widespread cortical phenomenon.
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Structural basis of multifunctional bovine mitochondrial cytochrome bc1 complex.
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Succinylcholine-induced hyperkalemia: effects of succinylcholine on resting potentials and electrolyte distributions in normal and denervated muscle.
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Synaptic Organization of Anterior Olfactory Nucleus Inputs to Piriform Cortex.
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Synaptic basis for developmental plasticity in a birdsong nucleus.
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Synaptic mechanism of pentylenetetrazole: selectivity for chloride conductance.
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Synaptic transformations underlying highly selective auditory representations of learned birdsong.
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Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: development of central cannabinoid receptor ligands with lower lipophilicity.
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Systematic mapping of the state dependence of voltage- and Ca2+-dependent inactivation using simple open-channel measurements.
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TRPA1 is a major oxidant sensor in murine airway sensory neurons.
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TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor.
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Tamoxifen and tamoxifen ethyl bromide induce apoptosis in acutely damaged mammary epithelial cells through modulation of AKT activity.
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Temperature dependence of the repulsive pressure between phosphatidylcholine bilayers.
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Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain.
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Temporal sequence and spatial distribution of early events of fertilization in single sea urchin eggs.
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Tension-stabilized pores in giant vesicles: determination of pore size and pore line tension.
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The action of dantrolene sodium on the lobster neuromuscular junction.
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The anion in salt taste: a possible role for paracellular pathways.
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The closed form solution to the periodic core-conductor model using asymptotic analysis.
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The discontinuous nature of propagation in normal canine cardiac muscle. Evidence for recurrent discontinuities of intracellular resistance that affect the membrane currents.
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The effect of xanthine/xanthine oxidase generated reactive oxygen species on synaptic transmission.
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The effects of quinidine and verapamil on electrically induced automaticity in the ventricular myocardium of guinea pig.
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The elimination of redundant preganglionic innervation to hamster sympathetic ganglion cells in early post-natal life.
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The estimation of sinoatrial conduction time in rabbit heart by the constant atrial pacing technique.
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The glitter of gold: biolistic transfection of fresh adult cardiac myocytes. Focus on "normal targeting of a tagged Kv1.5 channel acutely transfected into fresh adult cardiac myocytes by a biolistic method".
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The ionic mechanism of the slow outward current in Aplysia neurons.
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The neuromuscular blocking effects of therapeutic concentrations of various antibiotics on normal rat skeletal muscle: a quantitative comparison.
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The organization of n-alkanes in lipid bilayers.
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The potassium channel MBK1 (Kv1.1) is expressed in the mouse retina.
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The role of NMDA receptors in in vitro epileptogenesis.
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The role of ion fluxes in hematopoietic cell differentiation.
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The role restitution in pacing induced spiral wave acceleration.
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The secretory granule matrix-electrolyte interface: a homologue of the p-n rectifying junction.
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The variability of the electrical properties of the pulmonary veins.
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The voltage-dependent anion channel is a receptor for plasminogen kringle 5 on human endothelial cells.
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Theoretical characterization of ion channel blockade. Competitive binding to periodically accessible receptors.
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Three-dimensional finite element solution for biopotentials: erythrocyte in an applied field.
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Threshold variability in fibers with field stimulation of excitable membranes.
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Toward a Neurocentric View of Learning.
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Toxin and kinetic profile of rat brain type III sodium channels expressed in Xenopus oocytes.
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Transcriptional and functional profiles of voltage-gated Na(+) channels in injured and non-injured DRG neurons in the SNI model of neuropathic pain.
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Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels.
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Transport pathways in rat lingual epithelium.
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Transport properties of the calcium ionophore ETH-129.
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Tris buffer attenuates acetylcholine responses in Aplysia neurons.
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Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels.
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Unconventional serotonergic excitation in Aplysia.
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Unique functional properties of somatostatin-expressing GABAergic neurons in mouse barrel cortex.
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Unsaturated fatty acid requirement in Escherichia coli: mechanism of palmitate-induced inhibition of growth of strain WN1.
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Upstream regulatory role for XIAP in receptor-mediated apoptosis.
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Valproate reduces excitability by blockage of sodium and potassium conductance.
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Very long transients, irregular firing, and chaotic dynamics in networks of randomly connected inhibitory integrate-and-fire neurons.
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Virtual electrode effects in transvenous defibrillation-modulation by structure and interface: evidence from bidomain simulations and optical mapping.
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Voltage clamp analysis of pentylenetetrazol effects on Aplysia neurons.
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Voltage clamping with a single microelectrode.
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Voltage-dependent effects of opioid peptides on hippocampal CA3 pyramidal neurons in vitro.
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Voltage-dependent potassium currents of urethral afferent neurons in diabetes mellitus.
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Y+ and y+ L arginine transporters in neuronal cells expressing tyrosine hydroxylase.
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α1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current.
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β-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel.
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Keywords of People
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Erickson, Harold Paul,
Professor Emeritus of Cell Biology,
Cell Biology
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Field, Greg D.,
Adjunct Associate Professor of Neurobiology,
Neurobiology
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Henriquez, Craig S.,
Professor of Biomedical Engineering,
Biomedical Engineering
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Jordt, Sven Eric,
Associate Professor in Anesthesiology,
Pharmacology & Cancer Biology
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Neu, Wanda Krassowska,
Professor Emeritus of Biomedical Engineering,
Biomedical Engineering
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Pitt, Geoffrey Stuart,
Adjunct Professor in the Department of Medicine,
Medicine, Cardiology
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Starmer, Charles Franklin,
Professor Emeritus of Computer Science,
Computer Science