Menopause

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  Subject Areas on Research

  • " I take the good with the bad, and I moisturize": defying middle age in the new millennium. 
  • A pooled analysis of three studies of nonpharmacological interventions for menopausal hot flashes. 
  • A proposed classification system for menstrual cycles in the menopause transition based on changes in serum hormone profiles. 
  • A randomized, controlled pilot study of acupuncture treatment for menopausal hot flashes. 
  • A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer. 
  • A two-disease model of female breast cancer: mortality in 1969 among white females in the United States. 
  • Acupuncture in Menopause (AIM) study: a pragmatic, randomized controlled trial. 
  • Adiposity in relation to age at menarche and other reproductive factors among 300 000 Chinese women: findings from China Kadoorie Biobank study. 
  • Age and menopausal effects of hormonal birth control and hormone replacement therapy in relation to breast cancer risk. 
  • Age at natural menopause and the risk of epithelial ovarian cancer. 
  • Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample. 
  • Age at natural menopause in women exposed to diethylstilbestrol in utero. 
  • Aging and fertility patterns in wild chimpanzees provide insights into the evolution of menopause. 
  • Are there differences in symptoms experienced by midlife climacteric women with and without metabolic syndrome? A scoping review. 
  • Assessment of vulvar discomfort with sexual activity among women in the United States. 
  • Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk. 
  • Association between high-density lipoprotein cholesterol and breast cancer varies by menopausal status. 
  • Association of body composition with odds of breast cancer by molecular subtype: analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Nigerian Women (MEND) study. 
  • Associations of cortisol/testosterone and cortisol/sex hormone-binding globulin ratios with atherosclerosis in middle-age women. 
  • Associations of gender and a proxy of female menopausal status with histological features of drug-induced liver injury. 
  • Atypical estradiol secretion and ovulation patterns caused by luteal out-of-phase (LOOP) events underlying irregular ovulatory menstrual cycles in the menopausal transition. 
  • Bioavailability of estradiol as a marker for breast cancer risk assessment. 
  • Breast cancer and estrogen replacement therapy. 
  • Cancer-related fatigue. 
  • Changing trends and prognostic features in endometrial cancer associated with exogenous estrogen therapy. 
  • Characteristics and correlates of fatigue after adjuvant chemotherapy for breast cancer. 
  • Conditional estimation for generalized linear models when covariates are subject-specific parameters in a mixed model for longitudinal measurements. 
  • Consumption of dairy products and the risk of breast cancer: a review of the literature. 
  • Coping styles and personality domains related to menopausal stress. 
  • Correlates and Timing of Reproductive Aging Transitions in a Global Cohort of Midlife Women With Human Immunodeficiency Virus: Insights From the REPRIEVE Trial. 
  • Depression and insomnia in women. 
  • Depressive symptoms associated with physical health problems in midlife women: A longitudinal study. 
  • Depressive symptoms, menopausal status, and climacteric symptoms in women at midlife. 
  • Desvenlafaxine, a serotonin-norepinephrine uptake inhibitor for major depressive disorder, neuropathic pain and the vasomotor symptoms associated with menopause. 
  • Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans. 
  • Differences in bleeding phenotype and provider interventions in postmenarchal adolescents when compared to adult women with bleeding disorders and heavy menstrual bleeding. 
  • Do estradiol levels influence on the cognitive function during antidepressant treatments in post-menopausal women with major depressive disorder? A comparison with pre-menopausal women. 
  • Do menopausal status and use of hormone therapy affect antidepressant treatment response? Findings from the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study. 
  • Effects of exercise training on cardiovascular function and plasma lipid, lipoprotein, and apolipoprotein concentrations in premenopausal and postmenopausal women. 
  • Efficacy of soyfoods and soybean isoflavone supplements for alleviating menopausal symptoms is positively related to initial hot flush frequency. 
  • Emotional antecedents of hot flashes during daily life. 
  • Endocrine features of menstrual cycles in middle and late reproductive age and the menopausal transition classified according to the Staging of Reproductive Aging Workshop (STRAW) staging system. 
  • Endocrine therapy in metastatic breast cancer. 
  • Endometriosis and menopausal hormone therapy impact the hysterectomy-ovarian cancer association. 
  • Epidemiology of basal-like breast cancer. 
  • Estrogen and progesterone production by granulosa cell monolayers derived from in vitro fertilization procedures: lack of evidence for modulation by androgen. 
  • Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females. 
  • Female reproductive factors and major eye diseases in Asian women -the Singapore Malay Eye Study. 
  • Gender and menopause impact severity of fibrosis among patients with nonalcoholic steatohepatitis. 
  • Higher symptom burden is associated with lower function in women taking adjuvant endocrine therapy for breast cancer. 
  • Histopathologic distinctions in the relationship of estrogens and endometrial cancer. 
  • Hormonal and personal effects on estrogen receptors in breast cancer. 
  • Hormonal and reproductive risk factors for development of systemic lupus erythematosus: results of a population-based, case-control study. 
  • Hormonal management of menopausal symptoms in women with a history of gynecologic malignancy. 
  • Hormone and bone mineral status in endurance-trained and sedentary postmenopausal women. 
  • Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study. 
  • Identification of Symptom Clusters Among Midlife Menopausal Women with Metabolic Syndrome. 
  • Improving the identification of genitourinary syndrome of menopause through the utilization of the Day-to-Day Impact of Vaginal Aging questionnaire. 
  • Improving vasomotor symptoms; psychological symptoms; and health-related quality of life in peri- or post-menopausal women through yoga: An umbrella systematic review and meta-analysis. 
  • Initiation and discontinuation of hormone therapy for menopausal symptoms: results from a community sample. 
  • Intrinsic breast tumor subtypes, race, and long-term survival in the Carolina Breast Cancer Study. 
  • It's Getting Hot in Here: Piloting a Telemedicine OSCE Addressing Menopausal Concerns for Obstetrics and Gynecology Clerkship Students. 
  • Large prospective study of ovarian cancer screening in high-risk women: CA125 cut-point defined by menopausal status. 
  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. 
  • Lifestyle, occupational, and reproductive factors in relation to pancreatic cancer risk. 
  • Liver disease in menopause. 
  • Long-term follow-up of a phase II trial studying a weekly doxorubicin-based multiple drug adjuvant therapy for stage II node-positive carcinoma of the breast. 
  • Management of Menopausal Symptoms for Women Who Are at High Risk of Thrombosis. 
  • Management of Menopause Symptoms with Acupuncture: An Umbrella Systematic Review and Meta-Analysis. 
  • Management of adnexal mass. 
  • Married with children: predictors of mental and physical health in middle-aged women. 
  • Menopausal hormone therapy use and long-term all-cause and cause-specific mortality in the Long Island Breast Cancer Study Project. 
  • Menopausal hormones and breast cancer in a biracial population. 
  • Menopausal status, moderate-intensity walking, and symptoms in midlife women. 
  • Menopausal transition symptoms in midlife women living with fibromyalgia and chronic fatigue. 
  • Menopause and mood. Is depression linked with hormone changes? 
  • Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. 
  • Meta-analysis of loci associated with age at natural menopause in African-American women. 
  • Metabolic syndrome and risk of breast cancer mortality by menopause, obesity, and subtype. 
  • Necropsy diagnosis of endometrial cancer and detection-bias in case/control studies. 
  • Nephrolithiasis from calcium supplementation. 
  • Nonalcoholic fatty liver disease in women. 
  • Nonpharmacologic, nonherbal management of menopause-associated vasomotor symptoms: an umbrella systematic review (protocol). 
  • Nutritional risk and the metabolic syndrome in women: opportunities for preventive intervention from the Framingham Nutrition Study. 
  • Obesity and body fat distribution and breast cancer prognosis. 
  • Obesity, body fat distribution, and sex hormones in breast cancer patients. 
  • Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast. 
  • Oral contraceptives and breast cancer: a case-control study with hospital and community controls. 
  • Oral contraceptives and survival in breast cancer patients aged 20 to 54 years. 
  • Patient Sex, Reproductive Status, and Synthetic Hormone Use Associate With Histologic Severity of Nonalcoholic Steatohepatitis. 
  • Perceptions of menopausal stage and patterns of hormone replacement therapy use. 
  • Physical activity, weight, and waist circumference in midlife women. 
  • Polyfluoroalkyl chemicals and menopause among women 20-65 years of age (NHANES). 
  • Polymorphisms of the Interleukin 6 gene contribute to cervical cancer susceptibility in Eastern Chinese women. 
  • Predictors of mental health in midlife and older Australian women: A multilevel investigation. 
  • Progesterone receptor activity in leiomyomatosis peritonealis disseminata. 
  • Promoting informed decision making: hormone replacement therapy. 
  • Race, Menopausal Hormone Therapy, and Invasive Breast Cancer in the Carolina Breast Cancer Study. 
  • Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. 
  • Relationship of age and menopausal status to estrogen receptor content in primary carcinoma of the breast. 
  • Reply: "age at menopause: imputing age at menopause for women with a hysterectomy with application to risk of postmenopausal breast cancer". 
  • Reply: To PMID 24123276. 
  • Reproductive hormone levels in gynecologic oncology patients undergoing surgical castration after spontaneous menopause. 
  • Results of a pilot study of a cooling mattress pad to reduce vasomotor symptoms and improve sleep. 
  • Self reported morbidity and awareness regarding common cancers in elderly women. 
  • Sex and Menopause Modify the Effect of Single Nucleotide Polymorphism Genotypes on Fibrosis in NAFLD. 
  • Sex differences in incidence, pathophysiology, and outcome of primary intracerebral hemorrhage. 
  • Smoothing spline-based score tests for proportional hazards models. 
  • Stimulation protocols for patients with "atypical response". 
  • Stress reactivity and exercise training in premenopausal and postmenopausal women. 
  • Surgical Menopause and Frailty Risk in Community-Dwelling Older Women: Study of Osteoporotic Fractures. 
  • Survivorship, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology. 
  • Symptom communication in breast cancer: relationships of holding back and self-efficacy for communication to symptoms and adjustment. 
  • Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group. 
  • The association between in utero cigarette smoke exposure and age at menopause. 
  • The effects of perceived stress and attitudes toward menopause and aging on symptoms of menopause. 
  • The ethics of aggregation and hormone replacement therapy. 
  • The impact of menopause on functional status in women with rheumatoid arthritis. 
  • The influence of menopause status and postmenopausal use of hormone therapy on presentation of major depression in women. 
  • The perimenopausal patient in in vitro fertilization: the use of gonadotropin-releasing hormone. 
  • The role of acupuncture in treating menopausal hot flashes. 
  • The role of isoflavones in menopausal health: consensus opinion of The North American Menopause Society. 
  • The severity of vasomotor symptoms and number of menopausal symptoms in postmenopausal women and select clinical health outcomes in the Women's Health Initiative Calcium and Vitamin D randomized clinical trial. 
  • Timing of weight gain and breast cancer risk. 
  • Tuboovarian abscess in postmenopausal women. 
  • Use of alternative therapies in menopause. 
  • Use of mindfulness, meditation and relaxation to treat vasomotor symptoms. 
  • Using 4-vinylcyclohexene diepoxide as a model of menopause for cardiovascular disease. 
  • Variant genotypes of CDKN1A and CDKN1B are associated with an increased risk of breast cancer in Chinese women. 
  • Vasomotor Symptoms and Quality of Life Among Veteran and Non-Veteran Postmenopausal Women. 
  • Yoga of Awareness program for menopausal symptoms in breast cancer survivors: results from a randomized trial. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Ford, Anne Cunanan, Associate Professor of Obstetrics and Gynecology, Duke Women's Health - Heritage
  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology