Menopause

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  Subject Areas on Research

  • " I take the good with the bad, and I moisturize": defying middle age in the new millennium. 
  • "Being conditioned, yet becoming strong": Asian American women in menopausal transition. 
  • "Symptom-specific or holistic": menopausal symptom management. 
  • A descriptive Internet survey on menopausal symptoms: five ethnic groups of Asian American university faculty and staff. 
  • A feminist approach to research on menopausal symptom experience. 
  • A feminist critique of research on menopausal experience of Korean women. 
  • A national multiethnic online forum study on menopausal symptom experience. 
  • A pooled analysis of three studies of nonpharmacological interventions for menopausal hot flashes. 
  • A proposed classification system for menstrual cycles in the menopause transition based on changes in serum hormone profiles. 
  • A randomized, controlled pilot study of acupuncture treatment for menopausal hot flashes. 
  • A situation-specific theory of Asian immigrant women's menopausal symptom experience in the United States. 
  • A situation-specific theory of Korean immigrant women's menopausal transition. 
  • A situation-specific theory of Midlife Women's Attitudes Toward Physical Activity (MAPA). 
  • A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer. 
  • A two-disease model of female breast cancer: mortality in 1969 among white females in the United States. 
  • Acupuncture in Menopause (AIM) study: a pragmatic, randomized controlled trial. 
  • Adiposity in relation to age at menarche and other reproductive factors among 300 000 Chinese women: findings from China Kadoorie Biobank study. 
  • Age and menopausal effects of hormonal birth control and hormone replacement therapy in relation to breast cancer risk. 
  • Age at natural menopause and the risk of epithelial ovarian cancer. 
  • Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample. 
  • Age at natural menopause in women exposed to diethylstilbestrol in utero. 
  • Aging and fertility patterns in wild chimpanzees provide insights into the evolution of menopause. 
  • Anti-Müllerian hormone as a predictor of reproductive potential. 
  • Assessment of vulvar discomfort with sexual activity among women in the United States. 
  • Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk. 
  • Association between high-density lipoprotein cholesterol and breast cancer varies by menopausal status. 
  • Association of intrauterine and early-life exposures with age at menopause in the Sister Study. 
  • Associations of Immigration Transition to Cardiovascular Symptoms Experienced in Menopausal Transition. 
  • Associations of cortisol/testosterone and cortisol/sex hormone-binding globulin ratios with atherosclerosis in middle-age women. 
  • Associations of gender and a proxy of female menopausal status with histological features of drug-induced liver injury. 
  • Atypical estradiol secretion and ovulation patterns caused by luteal out-of-phase (LOOP) events underlying irregular ovulatory menstrual cycles in the menopausal transition. 
  • Bioavailability of estradiol as a marker for breast cancer risk assessment. 
  • Black women in menopausal transition. 
  • Breast cancer and estrogen replacement therapy. 
  • Cancer-related fatigue. 
  • Changing trends and prognostic features in endometrial cancer associated with exogenous estrogen therapy. 
  • Characteristics and correlates of fatigue after adjuvant chemotherapy for breast cancer. 
  • Clinical implications of ovarian reserve testing. 
  • Cluster analysis of midlife women's sleep-related symptoms: racial/ethnic differences. 
  • Clusters of midlife women identified by cognitive symptoms. 
  • Conditional estimation for generalized linear models when covariates are subject-specific parameters in a mixed model for longitudinal measurements. 
  • Consumption of dairy products and the risk of breast cancer: a review of the literature. 
  • Coping styles and personality domains related to menopausal stress. 
  • Cultural competence of measurement scales of menopausal symptoms: use in research among Korean women. 
  • Decreasing menopausal symptoms of Asian American breast cancer survivors through a technology-based information and coaching/support program. 
  • Decreasing sleep-related symptoms through increasing physical activity among Asian American midlife women. 
  • Depression and insomnia in women. 
  • Depressive symptoms, menopausal status, and climacteric symptoms in women at midlife. 
  • Desvenlafaxine, a serotonin-norepinephrine uptake inhibitor for major depressive disorder, neuropathic pain and the vasomotor symptoms associated with menopause. 
  • Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans. 
  • Differences in bleeding phenotype and provider interventions in postmenarchal adolescents when compared to adult women with bleeding disorders and heavy menstrual bleeding. 
  • Do estradiol levels influence on the cognitive function during antidepressant treatments in post-menopausal women with major depressive disorder? A comparison with pre-menopausal women. 
  • Effects of exercise training on cardiovascular function and plasma lipid, lipoprotein, and apolipoprotein concentrations in premenopausal and postmenopausal women. 
  • Effects of the body mass index on menopausal symptoms among Asian American midlife women using two different classification systems. 
  • Efficacy of soyfoods and soybean isoflavone supplements for alleviating menopausal symptoms is positively related to initial hot flush frequency. 
  • Emotional antecedents of hot flashes during daily life. 
  • Endocrine features of menstrual cycles in middle and late reproductive age and the menopausal transition classified according to the Staging of Reproductive Aging Workshop (STRAW) staging system. 
  • Endocrine therapy in metastatic breast cancer. 
  • Epidemiology of basal-like breast cancer. 
  • Estrogen and progesterone production by granulosa cell monolayers derived from in vitro fertilization procedures: lack of evidence for modulation by androgen. 
  • Ethnic differences in symptoms experienced during the menopausal transition. 
  • Ethnic differences in the clusters of menopausal symptoms. 
  • Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females. 
  • Experiencing transitions: an emerging middle-range theory. 
  • Female reproductive factors and major eye diseases in Asian women -the Singapore Malay Eye Study. 
  • Gender and menopause impact severity of fibrosis among patients with nonalcoholic steatohepatitis. 
  • Higher symptom burden is associated with lower function in women taking adjuvant endocrine therapy for breast cancer. 
  • Histopathologic distinctions in the relationship of estrogens and endometrial cancer. 
  • Hormonal and personal effects on estrogen receptors in breast cancer. 
  • Hormonal and reproductive risk factors for development of systemic lupus erythematosus: results of a population-based, case-control study. 
  • Hormone and bone mineral status in endurance-trained and sedentary postmenopausal women. 
  • Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study. 
  • Hormone therapy for the management of menopausal symptoms: pharmacotherapy update. 
  • Immigration transition and depressive symptoms: four major ethnic groups of midlife women in the United States. 
  • Immigration transition and sleep-related symptoms experienced during menopausal transition. 
  • Improving menopausal symptoms through promoting physical activity: a pilot Web-based intervention study among Asian Americans. 
  • Improving vasomotor symptoms; psychological symptoms; and health-related quality of life in peri- or post-menopausal women through yoga: An umbrella systematic review and meta-analysis. 
  • Initiation and discontinuation of hormone therapy for menopausal symptoms: results from a community sample. 
  • International consensus and practical guidelines on the gynecologic and obstetric management of female patients with hereditary angioedema caused by C1 inhibitor deficiency. 
  • Intrinsic breast tumor subtypes, race, and long-term survival in the Carolina Breast Cancer Study. 
  • Issues in an Internet survey among midlife Asian women. 
  • Large prospective study of ovarian cancer screening in high-risk women: CA125 cut-point defined by menopausal status. 
  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. 
  • Laser Therapy for Genitourinary Syndrome of Menopause. 
  • Lifestyle, occupational, and reproductive factors in relation to pancreatic cancer risk. 
  • Liver disease in menopause. 
  • Long-term follow-up of a phase II trial studying a weekly doxorubicin-based multiple drug adjuvant therapy for stage II node-positive carcinoma of the breast. 
  • Management of Menopausal Symptoms for Women Who Are at High Risk of Thrombosis. 
  • Management of Menopause Symptoms with Acupuncture: An Umbrella Systematic Review and Meta-Analysis. 
  • Management of adnexal mass. 
  • Managing menopause. 
  • Married with children: predictors of mental and physical health in middle-aged women. 
  • Menopausal hormones and breast cancer in a biracial population. 
  • Menopausal status, moderate-intensity walking, and symptoms in midlife women. 
  • Menopausal symptom experience of Hispanic midlife women in the United States. 
  • Menopausal symptom experience: an online forum study. 
  • Menopausal symptoms among four major ethnic groups in the United States. 
  • Menopausal symptoms and physical activity in multiethnic groups of midlife women: a secondary analysis. 
  • Menopausal transition of Korean immigrant women: a literature review. 
  • Menopausal transition symptoms in midlife women living with fibromyalgia and chronic fatigue. 
  • Menopause and mood. Is depression linked with hormone changes? 
  • Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. 
  • Meta-analysis of loci associated with age at natural menopause in African-American women. 
  • Metabolic syndrome and risk of breast cancer mortality by menopause, obesity, and subtype. 
  • Methodological issues in the recruitment of ethnic minority subjects to research via the Internet: a discussion paper. 
  • Midlife women's cardiovascular symptoms: A cluster analysis. 
  • Mother's menopausal age is associated with her daughter's early follicular phase urinary follicle-stimulating hormone level. 
  • Moxibustion for treating menopausal hot flashes: a randomized clinical trial. 
  • Necropsy diagnosis of endometrial cancer and detection-bias in case/control studies. 
  • Nephrolithiasis from calcium supplementation. 
  • Nonalcoholic fatty liver disease in women. 
  • Nonpharmacologic, nonherbal management of menopause-associated vasomotor symptoms: an umbrella systematic review (protocol). 
  • Nutritional risk and the metabolic syndrome in women: opportunities for preventive intervention from the Framingham Nutrition Study. 
  • Obesity and body fat distribution and breast cancer prognosis. 
  • Obesity, body fat distribution, and sex hormones in breast cancer patients. 
  • Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast. 
  • Oral contraceptives and breast cancer: a case-control study with hospital and community controls. 
  • Oral contraceptives and survival in breast cancer patients aged 20 to 54 years. 
  • Patient Sex, Reproductive Status, and Synthetic Hormone Use Associate With Histologic Severity of Nonalcoholic Steatohepatitis. 
  • Perceptions of menopausal stage and patterns of hormone replacement therapy use. 
  • Physical activities and sleep-related symptoms in 4 major racial/ethnic groups of midlife women. 
  • Physical activity, weight, and waist circumference in midlife women. 
  • Polyfluoroalkyl chemicals and menopause among women 20-65 years of age (NHANES). 
  • Polymorphisms of the Interleukin 6 gene contribute to cervical cancer susceptibility in Eastern Chinese women. 
  • Predictors of mental health in midlife and older Australian women: A multilevel investigation. 
  • Primary care in the postmenopausal woman. 
  • Progesterone receptor activity in leiomyomatosis peritonealis disseminata. 
  • Promoting informed decision making: hormone replacement therapy. 
  • Psychometric evaluation of the Midlife Women's Symptom Index in multiethnic groups. 
  • Race, Menopausal Hormone Therapy, and Invasive Breast Cancer in the Carolina Breast Cancer Study. 
  • Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. 
  • Racial/Ethnic Differences in Cardiovascular Symptoms in Four Major Racial/Ethnic Groups of Midlife Women: A Secondary Analysis. 
  • Racial/Ethnic Differences in Cognitive Symptoms During the Menopausal Transition. 
  • Recruitment of research participants through the Internet. 
  • Relationship of age and menopausal status to estrogen receptor content in primary carcinoma of the breast. 
  • Reply: "age at menopause: imputing age at menopause for women with a hysterectomy with application to risk of postmenopausal breast cancer". 
  • Reply: To PMID 24123276. 
  • Reproductive hormone levels in gynecologic oncology patients undergoing surgical castration after spontaneous menopause. 
  • Self reported morbidity and awareness regarding common cancers in elderly women. 
  • Sex differences in incidence, pathophysiology, and outcome of primary intracerebral hemorrhage. 
  • Sex differences in uric acid metabolism in adults: evidence for a lack of influence of estradiol-17 beta (E2) on the renal handling of urate. 
  • Sleep-related symptoms of midlife women with and without type 2 diabetes mellitus. 
  • Smoothing spline-based score tests for proportional hazards models. 
  • Stimulation protocols for patients with "atypical response". 
  • Stress reactivity and exercise training in premenopausal and postmenopausal women. 
  • Subethnic differences in the menopausal symptom experience of Asian American midlife women. 
  • Surgical Menopause and Frailty Risk in Community-Dwelling Older Women: Study of Osteoporotic Fractures. 
  • Survivorship, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology. 
  • Symptom communication in breast cancer: relationships of holding back and self-efficacy for communication to symptoms and adjustment. 
  • Symptoms experienced during menopausal transition: Korean women in South Korea and the United States. 
  • Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group. 
  • The Midlife Women's Symptom Index (MSI). 
  • The Psychometric Properties of the Midlife Women's Symptom Index. 
  • The association between in utero cigarette smoke exposure and age at menopause. 
  • The effects of perceived stress and attitudes toward menopause and aging on symptoms of menopause. 
  • The ethics of aggregation and hormone replacement therapy. 
  • The impact of menopause on functional status in women with rheumatoid arthritis. 
  • The impact of smoking on antimüllerian hormone levels in women aged 38 to 50 years. 
  • The perimenopausal patient in in vitro fertilization: the use of gonadotropin-releasing hormone. 
  • The psychobiology of premenstrual dysphoria: the role of prolactin. 
  • The psychometric properties of Pen-and-Pencil and Internet versions of the Midlife Women's Symptom Index (MSI). 
  • The relationships between psychological symptoms and cardiovascular symptoms experienced during the menopausal transition: racial/ethnic differences. 
  • The relationships of multiple factors to menopausal symptoms in different racial/ethnic groups of midlife women: The structural equation modeling. 
  • The role of acupuncture in treating menopausal hot flashes. 
  • The role of isoflavones in menopausal health: consensus opinion of The North American Menopause Society. 
  • Timing of weight gain and breast cancer risk. 
  • Tuboovarian abscess in postmenopausal women. 
  • Type 2 Diabetes and Musculoskeletal Symptoms Among Midlife Women. 
  • Use of alternative therapies in menopause. 
  • Use of mindfulness, meditation and relaxation to treat vasomotor symptoms. 
  • Variant genotypes of CDKN1A and CDKN1B are associated with an increased risk of breast cancer in Chinese women. 
  • Vasomotor Symptoms and Quality of Life Among Veteran and Non-Veteran Postmenopausal Women. 
  • Web-based interventions for menopause: A systematic integrated literature review. 
  • Women's work and symptoms during midlife: Korean immigrant women. 
  • Yoga of Awareness program for menopausal symptoms in breast cancer survivors: results from a randomized trial. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Moorman, Patricia Gripka, Professor in Family Medicine and Community Health, Duke Cancer Institute
  • Moreno, Anna C, Assistant Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Duke Women's Health Associates
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery