-
Subject Areas on Research
-
A 4-methyl-substituted meta-iodobenzylguanidine analogue with prolonged retention in human neuroblastoma cells.
-
A Population-Based Pharmacokinetic Model Approach to Pantoprazole Dosing for Obese Children and Adolescents.
-
A new era in pharmacotherapy: the need to understand the principles of therapeutic drug monitoring.
-
A nonantigenic covalent streptokinase-polyethylene glycol complex with plasminogen activator function.
-
A phase I clinical, plasma, and cellular pharmacology study of gemcitabine.
-
ACC/AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease. American College of Cardiology/American Heart Association.
-
Acute coronary care in the elderly, part I: Non-ST-segment-elevation acute coronary syndromes: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology.
-
An automated method for nonparametric kinetic analysis of clinical DCE-MRI data: application to glioblastoma treated with bevacizumab.
-
Anatomical and physiological basis for the allometric scaling of cisplatin clearance in dogs.
-
Antiepidermal growth factor variant III scFv fragment: effect of radioiodination method on tumor targeting and normal tissue clearance.
-
Antifungal pharmacodynamics: review of the literature and clinical applications.
-
Antitenascin antibody 81C6 armed with 177Lu: in vivo comparison of macrocyclic and acyclic ligands.
-
Bilateral native nephrectomy improves renal isograft function in rats.
-
Brief Report: Frequency of Monitoring Kidney Function in HIV-Uninfected Persons Using Daily Oral Tenofovir Disoproxil Fumarate Pre-exposure Prophylaxis.
-
Canine bombesin-like gastrin releasing peptides stimulate gastrin release and acid secretion in the dog.
-
Carbohydrate recognition systems in amphibians: primitive alpha 2-macroglobulin receptors.
-
Catabolic pathways for streptokinase, plasmin, and streptokinase activator complex in mice. In vivo reaction of plasminogen activator with alpha 2-macroglobulin.
-
Catabolism of 4-fluoro-3-iodobenzylguanidine and meta-iodobenzylguanidine by SK-N-SH neuroblastoma cells.
-
Cerebral blood flow values during cardiopulmonary bypass: relatively absolute or absolutely relative?
-
Characterization of alpha 2-macroglobulin-plasmin complexes: complete subunit cleavage alters receptor recognition in vivo and in vitro.
-
Characterization of liposomes containing iodine-125-labeled radiographic contrast agents.
-
Circulating and binding characteristics of wild-type factor IX and certain Gla domain mutants in vivo.
-
Clearance and distribution of recombinant murine gamma-interferon in mice.
-
Clearance from the anterior chamber of RBCs from human diabetics.
-
Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a relation between concentration and effect.
-
Clinical pharmacology of higher dose eptifibatide in percutaneous coronary intervention (the PRIDE study).
-
Comparison of [18 F]fluorocholine and [18 F]fluorodeoxyglucose for positron emission tomography of androgen dependent and androgen independent prostate cancer.
-
Critical care aspects of lung transplantation.
-
Dexmedetomidine Pharmacokinetics and a New Dosing Paradigm in Infants Supported With Cardiopulmonary Bypass.
-
Differences in the apparent metabolic clearance rate of testosterone in young and older men with gonadotropin suppression receiving graded doses of testosterone.
-
Differences in the metabolic response to exogenous homocysteine in juvenile and adult rabbits.
-
Differences in viral dynamics between genotypes 1 and 2 of hepatitis C virus.
-
Differential effects of ethanol in adolescent and adult rats.
-
Double-blind, randomized comparison of ondansetron and intraoperative propofol to prevent postoperative nausea and vomiting.
-
Drug Dosing and Pharmacokinetics in Children With Obesity: A Systematic Review.
-
Effect of Multi Drug Resistance Protein 4 (MRP4) Inhibition on the Pharmacokinetics and Pharmacodynamics of Ciprofloxacin in Normal and Rats with LPS-Induced Inflammation.
-
Effect of age on the pharmacokinetics of busulfan in patients undergoing hematopoietic cell transplantation; an alliance study (CALGB 10503, 19808, and 100103).
-
Effect of dietary fish oil supplementation on eicosanoid production by rat renal allografts.
-
Efficacy, tolerability, and kinetics of lamotrigine in infants.
-
Estimation of Body Fat Percentage for Clinical Pharmacokinetic Studies in Children.
-
Evaluation of an internalizing monoclonal antibody labeled using N-succinimidyl 3-[131I]iodo-4-phosphonomethylbenzoate ([131I]SIPMB), a negatively charged substituent bearing acylation agent.
-
Factors associated with reduced infliximab exposure in the treatment of pediatric autoimmune disorders: a cross-sectional prospective convenience sampling study.
-
Fasting and postprandial concentrations of GLP-1 in intestinal lymph and portal plasma: evidence for selective release of GLP-1 in the lymph system.
-
Fibrinolysis for acute myocardial infarction: current status and new horizons for pharmacological reperfusion, part 1.
-
Fluorescence imaging of blood-brain barrier disruption.
-
Fluorine-18-labeled [Nle4,D-Phe7]-alpha-MSH, an alpha-melanocyte stimulating hormone analogue.
-
Genome-wide study of methotrexate clearance replicates SLCO1B1.
-
Hepatic gadoxetic acid uptake as a measure of diffuse liver disease: Where are we?
-
Hepatic receptor that specifically binds oligosaccharides containing fucosyl alpha1 leads to 3 N-acetylglucosamine linkages.
-
High dose chemotherapy with autologous peripheral blood progenitor cell transplantation in an anephric child with multiply recurrent Wilms tumor.
-
Human/murine chimeric 81C6 F(ab')(2) fragment: preclinical evaluation of a potential construct for the targeted radiotherapy of malignant glioma.
-
Hyperparathyroidism and 1,25-dihydroxyvitamin D deficiency in mild, moderate, and severe renal failure.
-
Ifosfamide enantiomers: pharmacokinetics in children.
-
Impact of precontrast T10 relaxation times on dynamic contrast-enhanced MRI pharmacokinetic parameters: T10 mapping versus a fixed T10 reference value.
-
In vitro binding and in vivo clearance of human alpha 2-macroglobulin after reaction with endoproteases from four different classes.
-
In vivo catabolism of heparin cofactor II and its complex with thrombin: evidence for a common receptor-mediated clearance pathway for three serine proteinase inhibitors.
-
In vivo metabolism of inter-alpha-trypsin inhibitor and its proteinase complexes: evidence for proteinase transfer to alpha 2-macroglobulin and alpha 1-proteinase inhibitor.
-
In vivo metabolism of reversibly inhibited alpha-thrombin.
-
In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration.
-
Increasing uptake time in FDG-PET: standardized uptake values in normal tissues at 1 versus 3 h.
-
Initial low-dose gentamicin for Staphylococcus aureus bacteremia and endocarditis is nephrotoxic.
-
Intraindividual variability in male hepatic CYP3A4 activity assessed by alfentanil and midazolam clearance.
-
Intraperitoneal cisplatin and regional hyperthermia for ovarian carcinoma.
-
Intravascular coagulation--a source of possible error in carbon-clearance determinations.
-
Lack of indinavir effects on methadone disposition despite inhibition of hepatic and intestinal cytochrome P4503A (CYP3A).
-
Letrozole in the treatment of breast cancer.
-
Liposomal amphotericin B: clinical experience and perspectives.
-
Longitudinal Impact of Acute Spinal Cord Injury on Clinical Pharmacokinetics of Riluzole, a Potential Neuroprotective Agent.
-
Menstrual cycle variability in midazolam pharmacokinetics.
-
Methadone Pharmacogenetics: CYP2B6 Polymorphisms Determine Plasma Concentrations, Clearance, and Metabolism.
-
Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity.
-
Noncompartmental kinetic analysis of DCE-MRI data from malignant tumors: Application to glioblastoma treated with bevacizumab.
-
Novel marine-derived anticancer agents: a phase I clinical, pharmacological, and pharmacodynamic study of dolastatin 10 (NSC 376128) in patients with advanced solid tumors.
-
Optimal Dosing of Meropenem in a Small Cohort of Critically Ill Children Receiving Continuous Renal Replacement Therapy.
-
Oxygen and Perfusion Kinetics in Response to Fractionated Radiation Therapy in FaDu Head and Neck Cancer Xenografts Are Related to Treatment Outcome.
-
PET/CT mediastinal and liver FDG uptake: effects of biological and procedural factors.
-
Paramagnetic polymerized liposomes as new recirculating MR contrast agents.
-
Parathyroid lesions: characterization with dual-phase arterial and venous enhanced CT of the neck.
-
Patterns of internal and external tetraethylammonium block in four homologous K+ channels.
-
Peptide YY: metabolism and effect on pancreatic secretion in dogs.
-
Persistence of long, thin chrysotile asbestos fibers in the lungs of rats.
-
Pharmacodynamics and pharmacokinetics of higher-dose, double-bolus eptifibatide in percutaneous coronary intervention.
-
Pharmacokinetic and tolerance evaluation of actisomide, a new antiarrhythmic agent, in healthy volunteers.
-
Pharmacokinetics and biochemical effects of hepapoietin in patients with chronic liver disease.
-
Pharmacokinetics and safety of fluconazole in young infants supported with extracorporeal membrane oxygenation.
-
Pharmacokinetics and tumor localization of 131I-labeled anti-tenascin monoclonal antibody 81C6 in patients with gliomas and other intracranial malignancies.
-
Pharmacokinetics of cis-diamminedichloroplatinum(II) after administration in hypertonic saline.
-
Pharmacokinetics of diaziquone after three different dosage regimens.
-
Pharmacokinetics of doxorubicin administered i.v. as Myocet (TLC D-99; liposome-encapsulated doxorubicin citrate) compared with conventional doxorubicin when given in combination with cyclophosphamide in patients with metastatic breast cancer.
-
Pharmacokinetics of lamivudine in human immunodeficiency virus-infected patients with renal dysfunction.
-
Pharmacokinetics of oral triazolam in children.
-
Pharmacokinetics of zidovudine administered intravenously and orally in children with human immunodeficiency virus infection.
-
Phase I and pharmacokinetic study of 3'-C-ethynylcytidine (TAS-106), an inhibitor of RNA polymerase I, II and III,in patients with advanced solid malignancies.
-
Phase I evaluation of prolonged-infusion gemcitabine with fludarabine for relapsed or refractory acute myelogenous leukemia.
-
Phase I study to determine the safety and pharmacokinetics of oral administration of TAS-102 in patients with solid tumors.
-
Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma.
-
Phase II testing of melphalan in children with newly diagnosed rhabdomyosarcoma: a model for anticancer drug development.
-
Physiologic role for enhanced renal thromboxane production in murine lupus nephritis.
-
Population Pharmacokinetics of Durvalumab in Cancer Patients and Association With Longitudinal Biomarkers of Disease Status.
-
Population pharmacokinetics and pharmacodynamics of zidovudine in HIV-infected infants and children.
-
Population pharmacokinetics of NNZ-2566 in healthy subjects.
-
Population pharmacokinetics of enfuvirtide in pediatric patients with human immunodeficiency virus: searching for exposure-response relationships.
-
Population pharmacokinetics of fluconazole in young infants.
-
Population pharmacokinetics of micafungin in neonates and young infants.
-
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry.
-
Preclinical evaluation of 18F-JNJ41510417 as a radioligand for PET imaging of phosphodiesterase-10A in the brain.
-
Predictors of target organ damage in hypertensive blacks and whites.
-
Preparation of polyethylene glycol-tissue plasminogen activator adducts that retain functional activity: characteristics and behavior in three animal species.
-
Pyridazinones as selective cyclooxygenase-2 inhibitors.
-
Quantification of nicotinic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET.
-
Quantitative dynamic contrast-enhanced MRI of pelvic and lumbar bone marrow: effect of age and marrow fat content on pharmacokinetic parameter values.
-
Radioiodinated B6.2 monoclonal antibody: further characterization of a potential radiopharmaceutical for the identification of breast tumors.
-
Reduced arsenic clearance and increased toxicity in aquaglyceroporin-9-null mice.
-
Regional cerebral blood flow estimated by 133-xenon inhalation.
-
Resonating to the music of ubiquitination.
-
Respiratory physiology of house sparrows in relation to high-altitude flight.
-
Role of P-glycoprotein in the intestinal absorption and clinical effects of morphine.
-
Sex-related difference in the metabolism of isosorbide dinitrate following incubation in human blood.
-
Slow-release nanoparticle-encapsulated delivery system for laryngeal injection.
-
Soluble alpha2-macroglobulin receptor is increased in endotracheal aspirates from infants and children after cardiopulmonary bypass.
-
Suppression of glucose production by GLP-1 independent of islet hormones: a novel extrapancreatic effect.
-
Synthesis and evaluation of 4-[18F]fluoropropoxy-3-iodobenzylguanidine ([18F]FPOIBG): A novel 18F-labeled analogue of MIBG.
-
The binding of fucose-containing glycoproteins by hepatic lectins. Re-examination of the clearance from blood and the binding to membrane receptors and pure lectins.
-
The clearance of a monoclonal anti-DNA antibody following administration of DNA in normal and autoimmune mice.
-
The clearance of human fibrinogen fragments D1, D2, D3 and fibrin fragment D1 dimer in mice.
-
The clearance of human fibrinogen fragments X and Y in mice: a process mediated by the fragment D receptor.
-
The dynamics of ammonia metabolism in man. Effects of liver disease and hyperammonemia.
-
The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance).
-
Time course of carbamazepine autoinduction. The VA Cooperative Study No.118 Group.
-
Total-body creatine pool size and skeletal muscle mass determination by creatine-(methyl-D3) dilution in rats.
-
Toxicity and pharmacokinetics of the antibiotic fumagillin in yearling rainbow trout (Salmo gairdneri).
-
Vatalanib population pharmacokinetics in patients with myelodysplastic syndrome: CALGB 10105 (Alliance).
-
Keywords of People
-
-
Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
-
Chitneni, Satish K.,
Associate Professor in Radiology,
Radiology
-
Cohen-Wolkowiez, Michael,
Professor of Pediatrics,
Pediatrics, Infectious Diseases
-
Muir, Kelly Walton,
Associate Professor of Ophthalmology,
Ophthalmology, Glaucoma
-
Turkington, Timothy Garvey,
Associate Professor in Radiology,
Radiology