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Subject Areas on Research
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A plasma membrane-associated component of ovarian adenocarcinoma cells enhances the catalytic efficiency of matrix metalloproteinase-2.
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Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory.
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Aspartate release from rat hippocampal synaptosomes.
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Blockade of endothelin-converting enzyme reduces pulmonary hypertension after cardiopulmonary bypass and circulatory arrest.
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Cellular functions of metallo-endoproteinases.
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Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice.
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Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2.
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Cloning and characterization of a mammalian prenyl protein-specific protease.
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Collaborative Angiographic Patency Trial Of Recombinant Staphylokinase (CAPTORS II).
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Collaborative angiographic patency trial of recombinant staphylokinase (CAPTORS).
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Complement inactivating proteins and intraspecies venom variation in Crotalus oreganus helleri.
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Compromised atrial coronary anatomy is associated with atrial arrhythmias and atrioventricular block complicating acute myocardial infarction.
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Developmental expression of tissue inhibitor of metalloproteinase (TIMP) RNA.
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Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells.
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Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program.
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EP24.15 interacts with the angiotensin II type I receptor and bradykinin B2 receptor.
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Effect of cisplatin and BCNU on MMP-2 levels in human glioblastoma cell lines in vitro.
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Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors.
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Embryonic expression of mouse bone morphogenetic protein-1 (BMP-1), which is related to the Drosophila dorsoventral gene tolloid and encodes a putative astacin metalloendopeptidase.
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Engraftment of human synovium into severe combined immune deficient mice. Migration of human peripheral blood T cells to engrafted human synovium and to mouse lymph nodes.
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Evidence for involvement of metalloendoproteases in a step in sea urchin gamete fusion.
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Evidence for preferential adhesion of ovarian epithelial carcinoma cells to type I collagen mediated by the alpha2beta1 integrin.
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Evidence for the involvement of metalloendoproteases in the acrosome reaction in sea urchin sperm.
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Evolution of the gene encoding mitochondrial intermediate peptidase and its cosegregation with the A mating-type locus of mushroom fungi.
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Expression of genes for non-collagenous proteins during embryonic bone formation.
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Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid.
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Fatal outcome of bacteraemic patients caused by infection with staphylokinase-deficient Staphylococcus aureus strains.
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Gelatin/chondroitin 6-sulfate microspheres for the delivery of therapeutic proteins to the joint.
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IL-1 beta induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1 beta and IL-6 in human tendon cells.
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Induction of CD4(+) and CD8(+) T-cell responses to the human stromal antigen, fibroblast activation protein: implication for cancer immunotherapy.
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Induction of tissue-type plasminogen activator and 72-kDa type-IV collagenase by ionizing radiation in rat astrocytes.
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Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition.
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Inhibitors of metalloendoproteases block spiculogenesis in sea urchin primary mesenchyme cells.
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Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin.
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Kinetics and physiologic relevance of the inactivation of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, and antithrombin III by matrix metalloproteinases-1 (tissue collagenase), -2 (72-kDa gelatinase/type IV collagenase), and -3 (stromelysin).
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Matrix metalloproteinases and their inhibitors in human vitreous.
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Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord.
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Monitoring changes in gene expression in renal ischemia-reperfusion in the rat.
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Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion.
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Novel therapies for pancreatic adenocarcinoma.
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Parvalbumin Interneurons of the Mouse Nucleus Accumbens are Required For Amphetamine-Induced Locomotor Sensitization and Conditioned Place Preference.
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Pathogen Evasion of Chemokine Response Through Suppression of CXCL10.
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Protease inhibitors implicate metalloendoprotease in synaptic transmission at the mammalian neuromuscular junction.
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Rat myoblast fusion requires metalloendoprotease activity.
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Receptors for maleylated proteins regulate secretion of neutral proteases by murine macrophages.
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Reconstitution of mitochondrial processing peptidase from the core proteins (subunits I and II) of bovine heart mitochondrial cytochrome bc(1) complex.
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Renin-angiotensin system gene expression in post-transplant hypertension predicts allograft function.
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Requirement for metalloendoprotease in exocytosis: evidence in mast cells and adrenal chromaffin cells.
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SP75 is encoded by the DP87 gene and belongs to a family of modular Dictyostelium discoideum outer layer spore coat proteins.
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Screen and identification of proteins interacting with ADAM19 cytoplasmic tail.
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Secretion of extracellular matrix-degrading proteinases is increased in epithelial ovarian carcinoma.
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Specific blockers of myoblast fusion inhibit a soluble and not the membrane-associated metalloendoprotease in myoblasts.
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Specific inhibitors implicate a soluble metalloendoproteinase in exocytosis.
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Stromelysin-3 is overexpressed by stromal elements in primary non-small cell lung cancers and regulated by retinoic acid in pulmonary fibroblasts.
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Stromelysin-3 suppresses tumor cell apoptosis in a murine model.
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Structural remodelling in heart failure: gelatinase induction.
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Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice.
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System for expression of microsporidian methionine amino peptidase type 2 (MetAP2) in the yeast Saccharomyces cerevisiae.
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The chromosomal region containing pab-1, mip, and the A mating type locus of the secondarily homothallic homobasidiomycete Coprinus bilanatus.
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The effect of enzymatically degradable poly (ethylene glycol) hydrogels on smooth muscle cell phenotype
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The mammalian Tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart.
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The role of cytokines in posttraumatic arthritis.
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The soluble metalloendoprotease required in myoblast fusion remains intracellular.
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Two distinct forms of soluble MHC class I molecules synthesized by different mechanisms in normal rat cells in vitro.
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Type 2 angiotensin II receptor expression in human renal allografts: an association with chronic allograft nephropathy.
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Variation in Leishmania chemokine suppression driven by diversification of the GP63 virulence factor.
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Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme.
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Keywords of People