Mevalonic Acid
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Subject Areas on Research
- A case report of mevalonate kinase deficiency in a 14-month-old female with fevers and lower extremity weakness.
- Cilia loss sensitizes cells to transformation by activating the mevalonate pathway.
- Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases.
- G protein gamma subunits contain a 20-carbon isoprenoid.
- Growth inhibitory effects of aromatic fatty acids on ovarian tumor cell lines.
- Isoprenylation of a protein kinase. Requirement of farnesylation/alpha-carboxyl methylation for full enzymatic activity of rhodopsin kinase.
- Isoprenylation of the low molecular mass GTP-binding proteins rac 1 and rac 2: possible role in membrane localization.
- Role of small GTP-binding proteins in lovastatin-induced cataracts.
- Statin therapy inhibits fatty acid synthase via dynamic protein modifications.
- The Primary Effect on the Proteome of ARID1A-mutated Ovarian Clear Cell Carcinoma is Downregulation of the Mevalonate Pathway at the Post-transcriptional Level.
- Toxicity of oxidized low density lipoproteins for vascular smooth muscle cells and partial protection by antioxidants.
- p21ras is modified by a farnesyl isoprenoid.