Mice, Inbred NZB
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Subject Areas on Research
- Altered toll-like receptor responsiveness underlies a dominant heritable defect in B cell tolerance in autoimmune New Zealand Black mice.
- Antinuclear antibodies and nuclear antigens in NZB myeloma ascitic fluids.
- CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity.
- Effect os xid on anti-DNA B-cell precursors.
- Effects of bacterial DNA on cytokine production by (NZB/NZW)F1 mice.
- Expression of a highly conserved anti-DNA idiotype in normal and autoimmune mice.
- Germinal center B cell depletion diminishes CD4+ follicular T helper cells in autoimmune mice.
- Idiotypic analysis of a monoclonal anti-Sm antibody. II. Strain distribution of a common idiotypic determinant and its relationship to anti-Sm expression.
- Immunologic control of the ascites form of murine adenocarcinoma 755. III. Efficacy of serum therapy is controlled by a single genetic locus.
- Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA.
- Inhibition of in vitro NZB antibody responses by cyclosporine.
- Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA.
- Molecular properties of anti-DNA induced in preautoimmune NZB/W mice by immunization with bacterial DNA.
- Mycophenolate mofetil suppresses autoimmunity and mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus.
- Plasminogen alleles influence susceptibility to invasive aspergillosis.
- Protective and pathogenic roles for B cells during systemic autoimmunity in NZB/W F1 mice.
- Regulation of basement membrane-reactive B cells in BXSB, (NZBxNZW)F1, NZB, and MRL/lpr lupus mice.
- Regulatory B cells (B10 cells) have a suppressive role in murine lupus: CD19 and B10 cell deficiency exacerbates systemic autoimmunity.
- Relevance of systemic lupus erythematosus nephritis animal models to human disease.
- Specificity and idiotypic analysis of a monoclonal anti-Sm antibody with anti-DNA activity.
- Suppression of renal disease and mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE) by chenodeoxycholic acid.
- The antigenic properties of bacterial DNA in normal and aberrant immunity.
- The immunologic properties of DNA.
- The role of microparticles in the generation of immune complexes in murine lupus.
- Treatment with a laminin-derived peptide suppresses lupus nephritis.