-
Subject Areas on Research
-
4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors.
-
A Ras1-Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformans.
-
A candidate taste receptor gene near a sweet taste locus.
-
A genetic approach for studying the physiology of the type 1A (AT1A) angiotensin receptor.
-
A locus mapping to mouse chromosome 7 determines infarct volume in a mouse model of ischemic stroke.
-
A major role for the EP4 receptor in regulation of renin.
-
A neutralizing epitope of the superantigen SEA has agonist activity on T cells.
-
A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.
-
A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11.
-
A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program.
-
A role for angiotensin II type 1 receptors on bone marrow-derived cells in the pathogenesis of angiotensin II-dependent hypertension.
-
A single genetic locus determines the efficacy of serum therapy against murine adenocarcinoma 755a.
-
A work-performing heart preparation for myocardial performance analysis in murine hearts.
-
AT2 receptor and vascular smooth muscle cell differentiation in vascular development.
-
Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse.
-
Abundant androgen regulated mRNAs in mouse submandibular gland: cell-free translation of renin precursor mRNA.
-
Accelerated induction of experimental allergic encephalomyelitis in PL/J mice by a non-V beta 8-specific superantigen.
-
Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities.
-
Age-dependent alterations of peritoneal exudate macrophages in autoimmune-prone and autoimmune-resistant mouse strains.
-
Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide.
-
Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide.
-
Alopecia in IL-10-deficient mouse pups is c-kit-dependent and can be triggered by iron deficiency.
-
Alterations in inorganic phosphate in mouse hindlimb muscles during limb disuse.
-
Altered intragraft immune responses and improved renal function in MHC class II-deficient mouse kidney allografts.
-
Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP.
-
Altering and assessing persistence of genetically modified E. coli MG1655 in the large bowel.
-
An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria.
-
An anxiety-like phenotype in mice selectively bred for aggression.
-
An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models.
-
An imaging-based approach to identify ligands for olfactory receptors.
-
An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons.
-
Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury.
-
Angiotensin-(1-7) Attenuates Skeletal Muscle Fibrosis and Stiffening in a Mouse Model of Extremity Sarcoma Radiation Therapy.
-
Animal models provide insight into psychosomatic factors in diabetes.
-
Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites.
-
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation.
-
Anti-La antibody production by MRL-1pr/1pr mice. Analysis of fine specificity.
-
Anti-inflammatory and anti-osteoporotic activities of base-boronated nucleosides and phosphate-boronated nucleotides in rodents.
-
Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase.
-
Anti-mouse mesangial cell serum induces acute glomerulonephropathy in mice.
-
Antineoplastic activity of a series of boron analogues of alpha-amino acids.
-
Antinuclear antibodies and nuclear antigens in NZB myeloma ascitic fluids.
-
Basal epithelial stem cells are efficient targets for prostate cancer initiation.
-
Biosynthesis of renin: multiplicity of active and intermediate forms.
-
Body weight is not always a good predictor of longevity in mice.
-
Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism.
-
Bombesin increases fetal lung growth and maturation in utero and in organ culture.
-
Brain tumors in man and animals: report of a workshop.
-
CD44--a molecule involved in leukocyte adherence and T-cell activation.
-
Calcitonin gene-related peptide (CGRP) in the developing mouse limb.
-
Carcinogenicity and toxicity of inhaled nitrobenzene in B6C3F1 mice and F344 and CD rats.
-
Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation.
-
Cataract in mice congenitally infected with Toxoplasma gondii.
-
Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase.
-
Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice.
-
Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium.
-
Cellular requirements for anti-DNA production induced in mice by immunization with bacterial DNA.
-
Characteristics of Vibration that Alter Cardiovascular Parameters in Mice.
-
Characterization and expression of the complementary DNA encoding rat histidine decarboxylase.
-
Characterization and idiotypic analysis of an anti-RNP monoclonal antibody.
-
Characterization of a novel human corneal endothelial antigen.
-
Characterization of a spontaneous murine astrocytoma and abrogation of its tumorigenicity by cytokine secretion.
-
Characterization of glomerular thromboxane receptors in murine lupus nephritis.
-
Characterization of monoclonal antibodies with specificity for DNA and the synthetic polypeptide antigen (T,G)-A-L.
-
Characterization of the effects of endotoxin on macrophage tumor cell killing.
-
Characterization of the insulinotropic potency of polyunsaturated fatty acids.
-
Chemical denervation with botulinum neurotoxin a improves the surgical manipulation of the muscle-tendon unit: an experimental study in an animal model.
-
Chloroform inhalation exposure conditions necessary to initiate liver toxicity in female B6C3F1 mice.
-
Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci.
-
Ciliary neurotrophic factor receptor alpha mRNA in NB41A3 neuroblastoma cells: regulation by cAMP.
-
Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities.
-
Cloning genes that encode inducible forms of P-450.
-
Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper disks: phenotypic and genotypic analysis of B cell colonies.
-
Co-expression of vimentin and cytokeratins in parietal endoderm cells of early mouse embryo.
-
Comparison of in vitro and in vivo differentiation of myeloblastic leukemia of the RFM/Un mouse.
-
Comparison of pleural responses of rats and hamsters to subchronic inhalation of refractory ceramic fibers.
-
Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2.
-
Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease.
-
Computationally guided high-throughput design of self-assembling drug nanoparticles.
-
Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice.
-
Control of expression of insulin resistance and hyperglycemia by different genetic factors in diabetic C57BL/6J mice.
-
Cryptococcus neoformans gene involved in mammalian pathogenesis identified by a Caenorhabditis elegans progeny-based approach.
-
Cyclosporine inhibition of a murine B cell lymphoma.
-
Cysteine-tailed class I-binding peptides bind to CpG adjuvant and enhance primary CTL responses.
-
Deficits in reproduction and pro-gonadotropin-releasing hormone processing in male Cpefat mice.
-
Deletion of Y chromosome sequences located outside the testis determining region can cause XY female sex reversal.
-
Depletion of polymorphonuclear leukocytes has no effect on preterm delivery in a mouse model of Escherichia coli-induced labor.
-
Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture.
-
Detection of the major glycoproteins of Friend leukemia virus (gp71) and the murine mammary tumor virus (gp52) on the surface of mouse cells.
-
Diabetic kidney disease in FVB/NJ Akita mice: temporal pattern of kidney injury and urinary nephrin excretion.
-
Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis.
-
Diacylglycerol kinase ζ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responses.
-
Diazoxide restores beta3-adrenergic receptor function in diet-induced obesity and diabetes.
-
Differential effects of vascular endothelial growth factor receptor-2 inhibitor ZD6474 on circulating endothelial progenitors and mature circulating endothelial cells: implications for use as a surrogate marker of antiangiogenic activity.
-
Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo.
-
Differential glycemic effects of morphine in diabetic and normal mice.
-
Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.
-
Disruption of intrathymic CD4-Ia interactions on immature CD4+CD8+ thymocytes results in diminished TCR expression on mature CD8+ T cell progeny.
-
Divergent pathways mediate the induction of ANF transgenes in neonatal and hypertrophic ventricular myocardium.
-
Dose-dependent effect of melatonin on life span and spontaneous tumor incidence in female SHR mice.
-
E2-induced degradation of uterine insulin receptor substrate-2: requirement for an IGF-I-stimulated, proteasome-dependent pathway.
-
Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice.
-
Effect of basic fibroblast growth factor on angiogenesis and growth of isografted bone: quantitative in vitro-in vivo analysis in mice.
-
Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice.
-
Effect of fatty acids on insulin release: role of chain length and degree of unsaturation.
-
Effect of neuronol on lifespan and development of spontaneous tumors in SAMP-1 mice with genetically accelerated aging.
-
Effects of IL-1 on hematopoietic progenitors after myelosuppressive chemoradiotherapy.
-
Effects of murine cytomegalovirus infection on the immune response to a tumor allograft.
-
Effects of the kinase inhibitor sorafenib on heart, muscle, liver and plasma metabolism in vivo using non-targeted metabolomics analysis.
-
Ehd4 is required to attain normal prepubertal testis size but dispensable for fertility in male mice.
-
Ejaculatory abnormalities in mice with targeted disruption of the gene for heme oxygenase-2.
-
Embryonic germ cell lines and their derivation from mouse primordial germ cells.
-
Endogenous production of extracellular adenosine by trabecular meshwork cells: potential role in outflow regulation.
-
Enhanced growth of small bowel in transgenic mice overexpressing bovine growth hormone.
-
Enhancement of endocrine pancreatic secretions by essential fatty acids.
-
Enhancement of experimental anaerobic infections by blood, hemoglobin, and hemostatic agents.
-
Epidermal growth factor replaces estrogen in the stimulation of female genital-tract growth and differentiation.
-
Essential role of LAT in T cell development.
-
EuroPhenome: a repository for high-throughput mouse phenotyping data.
-
Evidence for an immune barrier after in utero hematopoietic-cell transplantation.
-
Evidence for the existence of renin in the heart.
-
Evidence for two cellular pathways of renin secretion by the mouse submandibular gland.
-
Evidence of CNIH3 involvement in opioid dependence.
-
Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans.
-
Exogenous Hsp70 delays senescence and improves cognitive function in aging mice.
-
Expression of Mls determinants in mice exhibiting the severe combined immunodeficiency (scid) mutation or X-linked immunodeficiency (xid) defect.
-
Expression of a murine cytomegalovirus early-late protein in "latently" infected mice.
-
Expression of transforming growth factor beta 2 RNA during murine embryogenesis.
-
FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells.
-
Facilitative glucose transporter Glut1 is actively excluded from rod outer segments.
-
Flow cytometric detection of lymphocyte proliferation in eyes with immunogenic inflammation.
-
Gallbladder glycoprotein secretion in mice with hemolytic anemia and pigment gallstones.
-
Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation.
-
Gene expression profiles of RAW264.7 macrophages stimulated with preparations of LPS differing in isolation and purity.
-
Gene expression profiling reveals progesterone-mediated cell cycle and immunoregulatory roles of Hoxa-10 in the preimplantation uterus.
-
Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans.
-
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.
-
Genetic basis of murine responses to hyperoxia-induced lung injury.
-
Genetic control of inflammatory arthritis and glomerulonephritis in congenic lpr mice and their F1 hybrids.
-
Genetic control of the immune response to nuclease. V. Genetic linkage and strain distribution of anti-nuclease idiotypes.
-
Genetic control of the immune response to staphylococcal nuclease. VII. Role of non-H2-linked genes in the control of the anti-nuclease antibody response.
-
Genetic control of the immune response to staphylococcal nuclease. VIII. Mapping of genes for antibodies to different antigenic regions of nuclease.
-
Genetic dissection of the mouse brain using high-field magnetic resonance microscopy.
-
Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice.
-
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.
-
Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans.
-
Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells.
-
Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells.
-
Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis.
-
H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejection.
-
Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4.
-
Helix-loop-helix transcription factors E12 and E47 are not essential for skeletal or cardiac myogenesis, erythropoiesis, chondrogenesis, or neurogenesis.
-
Heparin binding EGF is necessary for vasospastic response to endothelin.
-
High oxygen prevents fetal lethality due to lack of catecholamines.
-
High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping.
-
High-frequency alloreactive T cells augment effector function of low-frequency CD8+ T-cell responses under CD28/CD154 blockade.
-
Host genetic variation in susceptibility to Punta Toro virus.
-
Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits.
-
Hypertension in CB57BL/6J mouse model of non-insulin-dependent diabetes mellitus.
-
Hypolipidemic activity of boronated nucleosides and nucleotides in rodents.
-
Hypolipidemic activity of tetrakis-mu-(trimethylamine-boranecarboxylato)-bis(trimethylamin e- carboxyborane)-dicopper(II) in rodents and its effect on lipid metabolism.
-
Hypoxia modulates nitric oxide-induced regulation of NMDA receptor currents and neuronal cell death.
-
ICAM-1 expression in autoimmune encephalitis visualized using magnetic resonance imaging.
-
Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.
-
Idiotypic cross-reaction between MRL monoclonal autoantibodies with different antigen specificity.
-
IgG binding of monoclonal anti-nuclear antibodies from MRL-lpr/lpr mice.
-
Immunization with the Sm nuclear antigen induces anti-Sm antibodies in normal and MRL mice.
-
Immunodominant liver-specific expression suppresses transgene-directed immune responses in murine pompe disease.
-
Immunofluorescent analysis of expression of the RNA tumor virus major glycoprotein, gp71, on the surfaces of normal murine cells.
-
Immunogenic determinants of a neuropathogenic murine leukemia virus.
-
Immunologic control of the ascites of murine adenocarcinoma 755. I. Protection with syngeneic immune serum or lymphoid cells.
-
Immunological consequences of transplanting rat insulinomas.
-
Impact of genetic background on nephropathy in diabetic mice.
-
Impaired second phase insulin response of diabetes-prone C57BL/6J mouse islets.
-
In vitro and in vivo investigations for the development of cytostatic methylhydrazones.
-
In vitro survival and differentiation of neurons derived from epidermal growth factor-responsive postnatal hippocampal stem cells: inducing effects of brain-derived neurotrophic factor.
-
In vivo antigenic modification of tumor cells. I. Introduction of murine leukemia virus antigens on non-virus-producing murine sarcomas.
-
In vivo antigenic modification of tumor cells. II. Distribution of virus in sarcoma-bearing mice.
-
In vivo antigenic modification of tumor cells. III. Metastatic thymic lymphoma specifically infected by thymotropic retrovirus.
-
In vivo models for studying mast cell-dependent responses to bacterial infection.
-
In vivo modulation of macrophage tumoricidal activity: enhanced tumor cell killing by peritoneal macrophages from mice given injections of sodium periodate.
-
In vivo photoacoustic imaging of transverse blood flow by using Doppler broadening of bandwidth.
-
Inactivation of murine xenotropic oncornavirus by normal mouse sera is not immunoglobulin-mediated.
-
Increasing fructose 2,6-bisphosphate overcomes hepatic insulin resistance of type 2 diabetes.
-
Inducible nitric oxide synthase promotes cytokine expression in cardiac allografts but is not required for efficient rejection.
-
Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA.
-
Induction of immune-mediated glomerulonephritis in normal mice immunized with bacterial DNA.
-
Influence of genotype, dose and sex on pruritogen-induced scratching behavior in the mouse.
-
Influence of nociception and stress-induced antinociception on genetic variation in isoflurane anesthetic potency among mouse strains.
-
Inhibition of in vitro anti-DNA B-cell responses by cyclosporine.
-
Inhibition of murine cytotoxic T lymphocyte activity by a synthetic retroviral peptide and abrogation of this activity by IL.
-
Initial displacement of the intra-articular surface after articular fracture correlates with PTA in C57BL/6 mice but not "superhealer" MRL/MpJ mice.
-
Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program.
-
Initial testing (stage 1) of the BH3 mimetic ABT-263 by the pediatric preclinical testing program.
-
Initial testing (stage 1) of the proteasome inhibitor bortezomib by the pediatric preclinical testing program.
-
Initial testing of VNP40101M (Cloretazine) by the pediatric preclinical testing program.
-
Initial testing of dasatinib by the pediatric preclinical testing program.
-
Insulin in aging and cancer: antidiabetic drug Diabenol as geroprotector and anticarcinogen.
-
Interferon suppresses pinocytosis but stimulates phagocytosis in mouse peritoneal macrophages: related changes in cytoskeletal organization.
-
Intrinsic and induced regulation of the age-associated onset of spontaneous experimental autoimmune encephalomyelitis.
-
Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles.
-
Investigation of antiestrogenic properties of unleaded gasoline in female mice.
-
Involvement of multiple factors in the clonal deletion of self-reactive T cells.
-
Kinetics of release of serotonin from isolated secretory granules. I. Amperometric detection of serotonin from electroporated granules.
-
Kinetics of release of serotonin from isolated secretory granules. II. Ion exchange determines the diffusivity of serotonin.
-
Lactobacillus rhamnosus GG improves outcome in experimental pseudomonas aeruginosa pneumonia: potential role of regulatory T cells.
-
Lactoferrin expression in the mouse reproductive tract during the natural estrous cycle: correlation with circulating estradiol and progesterone.
-
Left ventricular hypertrophy in ascending aortic stenosis mice: anoikis and the progression to early failure.
-
Left ventricular volumes and function in the embryonic mouse heart.
-
Lens fiber cell elongation and differentiation is associated with a robust increase in myosin light chain phosphorylation in the developing mouse.
-
Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse.
-
Local production of TGF beta1 inhibits cerebral edema, enhances TNF-alpha induced apoptosis and improves survival in a murine glioma model.
-
Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system.
-
Long- and short-lived murine hematopoietic stem cell clones individually identified with retroviral integration markers.
-
Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles.
-
Long-term stability of electroenzymatic glucose sensors implanted in mice. An update.
-
Loss of atm radiosensitizes multiple p53 null tissues.
-
Low plasma leptin in response to dietary fat in diabetes- and obesity-prone mice.
-
Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model.
-
Macrophage polykaryon formation in vitro by peritoneal cells from mice given injections of sodium periodate.
-
Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice.
-
Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity.
-
Mechanisms of autoantibody production in autoimmune MRL mice.
-
Mechanisms of tolerance induced by PG490-88 in a bone marrow transplantation model.
-
Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy.
-
Metabolism and distribution of norethynodrel in pregnant and nonpregnant mice.
-
Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice.
-
Metabolomic analysis of insulin resistance across different mouse strains and diets.
-
Metastatic prostate cancer in a transgenic mouse.
-
Migration of mesonephric cells into the mammalian gonad depends on Sry.
-
Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination.
-
Mitosis is required for production of murine leukemia virus and structural proteins during de novo infection.
-
Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA.
-
Molecular and genetic characterization of a radiation-induced structural rearrangement in mouse chromosome 2 causing mutations at the limb deformity and agouti loci.
-
Molecular genetic mechanisms of allelic specific regulation of murine Comt expression.
-
Monoclonal rheumatoid factors from B6-lpr/lpr mice.
-
Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines.
-
Multivalent cross-linking of membrane Ig sensitizes murine B cells to a broader spectrum of CpG-containing oligodeoxynucleotide motifs, including their methylated counterparts, for stimulation of proliferation and Ig secretion.
-
Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo.
-
Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence.
-
Muscle wasting and interleukin-6-induced atrogin-I expression in the cachectic Apc ( Min/+ ) mouse.
-
Mutant mice and neuroscience: recommendations concerning genetic background. Banbury Conference on genetic background in mice.
-
Mycophenolate mofetil suppresses autoimmunity and mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus.
-
Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury.
-
NOV (CCN3) regulation in the growth plate and CCN family member expression in cartilage neoplasia.
-
Neem oil inhibits two-cell embryo development and trophectoderm attachment and proliferation in vitro.
-
Neonatal W-mutant mice are favorable hosts for tracking development of marked hematopoietic stem cells.
-
Nephrotoxicity and hepatotoxicity induced by inhaled bromodichloromethane in wild-type and p53-heterozygous mice.
-
Neural induction and patterning in the mouse in the absence of the node and its derivatives.
-
Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling.
-
Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.
-
Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection.
-
Nitric oxide regulation of myocardial contractility and calcium cycling: independent impact of neuronal and endothelial nitric oxide synthases.
-
Nitrosylation of blood hemoglobin and renal nonheme proteins in autoimmune MRL-lpr/lpr mice.
-
Noninvasively induced degeneration of neocortical pyramidal neurons in vivo: selective targeting by laser activation of retrogradely transported photolytic chromophore.
-
Notch-dependent differentiation of adult airway basal stem cells.
-
Novel MRI and fluorescent probes responsive to the Factor XIII transglutaminase activity.
-
One small step for mice, one giant leap for GWAS?
-
Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A).
-
Overexpression of extracellular superoxide dismutase decreases lung injury after exposure to oil fly ash.
-
Oxidative stress and inflammation contribute to lung toxicity after a common breast cancer chemotherapy regimen.
-
PG27, an extract of Tripterygium wilfordii hook f, induces antigen-specific tolerance in bone marrow transplantation in mice.
-
Paclitaxel-induced neuropathic hypersensitivity in mice: responses in 10 inbred mouse strains.
-
Pain modality- and sex-specific effects of COMT genetic functional variants.
-
Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP.
-
Peripheral mobilization of recipient bone marrow-derived endothelial progenitor cells enhances pancreatic islet revascularization and engraftment after intraportal transplantation.
-
Permeability of different experimental brain tumor models to horseradish peroxidase.
-
Phenylalanine hydroxylase in dilute lethal mice.
-
Phorbol diester-induced H2O2 production by peritoneal macrophages. Different H2O2 production by macrophages from normal and BCG-infected mice despite comparable phorbol diester receptors.
-
Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity.
-
Physiologic role for enhanced renal thromboxane production in murine lupus nephritis.
-
Piezo-assisted nuclear transfer affects cloning efficiency and may cause apoptosis.
-
Plasma FGF23 levels increase rapidly after acute kidney injury.
-
Postnatal construction of neural circuitry in the mouse olfactory bulb.
-
Potentiation of diethylstilbestrol-induced alterations in the female mouse reproductive tract by transforming growth factor-alpha transgene expression.
-
Pparg-P465L mutation worsens hyperglycemia in Ins2-Akita female mice via adipose-specific insulin resistance and storage dysfunction.
-
Prevention of graft-versus-host disease by a novel immunosuppressant, PG490-88, through inhibition of alloreactive T cell expansion.
-
Prevention of graft-versus-host disease while preserving graft-versus-leukemia effect after selective depletion of host-reactive T cells by photodynamic cell purging process.
-
Production and role of cytokines in the CNS of mice with acute viral encephalomyelitis.
-
Prolonged survival of class II transactivator-deficient cardiac allografts.
-
Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes.
-
Properties of multilamellar liposomes containing 99mTcO4-: effect of distearoylphosphatidylcholine to sphingomyelin ratio.
-
Proteolytic activity and immunogenicity of oral bromelain within the gastrointestinal tract of mice.
-
Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles.
-
Qa-2-dependent selection of CD8alpha/alpha T cell receptor alpha/beta(+) cells in murine intestinal intraepithelial lymphocytes.
-
Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes.
-
RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance.
-
Rapamycin suppression of host-versus-graft and graft-versus-host disease in MHC-mismatched rats.
-
Regulation of E2A gene expression in B-lymphocyte development.
-
Regulation of IgE synthesis: introduction.
-
Regulation of flt-1 expression during mouse embryogenesis suggests a role in the establishment of vascular endothelium.
-
Regulation of local and metastatic host-mediated anti-tumour mechanisms by L-selectin and intercellular adhesion molecule-1.
-
Regulation of sodium balance and blood pressure by the AT(1A) receptor for angiotensin II.
-
Regulation of the anti-Sm autoantibody response in systemic lupus erythematosus mice by monoclonal anti-Sm antibodies.
-
Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis.
-
Regulatory genes linked to the albino locus in the mouse confer competence for inducible expression on the structural gene encoding serine dehydratase.
-
Renal tubular cell expression of MHC class II (I-Eb) is insufficient to initiate immune injury in a transgenic kidney transplant model.
-
Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia.
-
Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions.
-
Retinoic acid induction and regional differentiation prefigure olfactory pathway formation in the mammalian forebrain.
-
Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis.
-
Revisiting lessons from the C57BL/6J mouse.
-
Role for hedgehog pathway in regulating growth and function of invariant NKT cells.
-
Rous sarcoma virus-induced tumours in mice. II. Contribution of H-2 and non-H-2 alloantigen barriers to tumour immunogenicity in vivo.
-
Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways.
-
Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes.
-
Sequence elements required for transcriptional activity of the human myoglobin promoter in intact myocardium.
-
Serine/threonine phosphorylation regulates HNF-4alpha-dependent redox-mediated iNOS expression in hepatocytes.
-
Sertoli cell ablation and replacement of the spermatogonial niche in mouse.
-
Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy.
-
Single-cell imaging of T cell immunotherapy responses in vivo.
-
Species differences in cardiac thyroid hormone receptor isoforms protein abundance.
-
Specific transforming potential of oncogenes encoding protein-tyrosine kinases.
-
Specificity analysis of monoclonal anti-DNA antibodies from B6-lpr/lpr mice.
-
Specificity analysis of monoclonal anti-DNA antibodies.
-
Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4.
-
Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA.
-
Stochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cells.
-
Structural features of nephritogenic lupus autoantibodies.
-
Structure of the genes encoding the CD19 antigen of human and mouse B lymphocytes.
-
Studies on the mechanism and specificity of the effect of the synthetic random copolymer GLAT on graft-versus-host disease.
-
Successful tumour immunotherapy: possible role of antibodies to anti-inflammatory factors produced by neoplasms.
-
Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice.
-
Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance.
-
Synergy between tumor immunotherapy and antiangiogenic therapy.
-
Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice.
-
Targeted inhibition of beta-adrenergic receptor kinase-1-associated phosphoinositide-3 kinase activity preserves beta-adrenergic receptor signaling and prolongs survival in heart failure induced by calsequestrin overexpression.
-
Targeting molecular and cellular inhibitory mechanisms for improvement of antitumor memory responses reactivated by tumor cell vaccine.
-
Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers.
-
Tenascin is induced at implantation sites in the mouse uterus and interferes with epithelial cell adhesion.
-
Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction.
-
Testosterone regulates cell proliferation in aggressive fibromatosis (desmoid tumour).
-
The HMG-CoA reductase inhibitor pravastatin stimulates insulin secretion through organic anion transporter polypeptides.
-
The IFN pregnancy recognition hormone IFN-tau blocks both development and superantigen reactivation of experimental allergic encephalomyelitis without associated toxicity.
-
The acute toxicity of drugs acting at cholinoceptive sites and twenty-four hour rhythms in brain acetylcholine.
-
The androgen-binding protein gene is expressed in CD1 mouse testis.
-
The anti-La response of a single MRL/Mp-lpr/lpr mouse: specificity for DNA and VH gene usage.
-
The binding of fucose-containing glycoproteins by hepatic lectins. Re-examination of the clearance from blood and the binding to membrane receptors and pure lectins.
-
The clearance of a monoclonal anti-DNA antibody following administration of DNA in normal and autoimmune mice.
-
The clearance of human fibrinogen fragments X and Y in mice: a process mediated by the fragment D receptor.
-
The fine specificity of anti-La antibodies induced in mice by immunization with recombinant human La autoantigen.
-
The immune response to staphylococcal nuclease: a probe of cellular and humoral antigen-specific receptors.
-
The induction of tolerance and suppression in autoimmune MRL mice using hapten-modified self.
-
The influence of Yaa on anti-DNA responses of B6-lpr mice.
-
The influence of the lpr gene on B cell activation: differential antibody expression in lpr congenic mouse strains.
-
The production and characterization of murine monoclonal antibodies to human Gadd45 raised against a recombinant protein.
-
The role of CD4-Lck in T-cell receptor antagonism: evidence for negative signaling.
-
The role of GABAB receptor activation in absence seizures of lethargic (lh/lh) mice.
-
The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: differential effects in rats and mice.
-
Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture.
-
Three-dimensional structure of the developing mouse genital ridge.
-
Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.
-
Thromboxane augmentation of alloreactive T cell function.
-
Tnni3k modifies disease progression in murine models of cardiomyopathy.
-
Transferrin receptor is necessary for development of erythrocytes and the nervous system.
-
Transgenic expression of pancreatic secretory trypsin inhibitor-I ameliorates secretagogue-induced pancreatitis in mice.
-
Transgenic indicator mice for studying activated retinoic acid receptors during development.
-
Transgenic tubular cell expression of class II is insufficient to initiate immune renal injury.
-
Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia.
-
Tumor cells cotransduced with B7.1 and gamma-IFN induce effective rejection of established parental tumor.
-
Tumor-dendritic cell fusion as a basis for cancer immunotherapy.
-
Tumorigenic cell culture lines from a spontaneous VM/Dk murine astrocytoma (SMA).
-
Two-photon molecular excitation imaging of Ca2+ transients in Langendorff-perfused mouse hearts.
-
Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages.
-
Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene.
-
Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice.
-
Vascular control of kidney epithelial transporters.
-
Velocity differences between L- and P-selectin-dependent neutrophil rolling in venules of mouse cremaster muscle in vivo.
-
Very-long-chain acyl-coenzyme a dehydrogenase deficiency in mice.
-
Viral infection-homograft interactions in a murine model.
-
Vital imaging of glomeruli in the mouse olfactory bulb.
-
Zinc inhibits turnover of labile mRNAs in intact cells.
-
c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice.
-
Keywords of People
-
-
-
-
Choi, Steven Sok,
Associate Professor of Medicine,
Medicine, Gastroenterology
-
Erickson, Harold Paul,
James B. Duke Distinguished Professor Emeritus,
Cell Biology
-
Gunn, Michael Dee,
Professor of Medicine,
Integrative Immunobiology
-
Hogan, Brigid L. M.,
Research Professor of Cell Biology,
Cell Biology
-
Johnson, G. Allan,
Charles E. Putman University Distinguished Professor of Radiology,
Biomedical Engineering
-
Kelsoe, Garnett H.,
James B. Duke Distinguished Professor of Immunology,
Integrative Immunobiology
-
Sampson, John Howard,
Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine,
Biomedical Engineering
-
Tsalik, Ephraim,
Adjunct Associate Professor in the Department of Medicine,
Medicine, Infectious Diseases