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Subject Areas on Research
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4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors.
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A Ras1-Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformans.
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A candidate taste receptor gene near a sweet taste locus.
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A genetic approach for studying the physiology of the type 1A (AT1A) angiotensin receptor.
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A highly selective inhibitor of IkappaB kinase, BMS-345541, augments graft survival mediated by suboptimal immunosuppression in a murine model of cardiac graft rejection.
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A locus mapping to mouse chromosome 7 determines infarct volume in a mouse model of ischemic stroke.
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A major role for the EP4 receptor in regulation of renin.
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A matrix for new ideas in pulmonary fibrosis.
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A neutralizing epitope of the superantigen SEA has agonist activity on T cells.
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A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11.
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A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program.
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A role for angiotensin II type 1 receptors on bone marrow-derived cells in the pathogenesis of angiotensin II-dependent hypertension.
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A single genetic locus determines the efficacy of serum therapy against murine adenocarcinoma 755a.
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AT2 receptor and vascular smooth muscle cell differentiation in vascular development.
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Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse.
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Abundant androgen regulated mRNAs in mouse submandibular gland: cell-free translation of renin precursor mRNA.
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Accelerated induction of experimental allergic encephalomyelitis in PL/J mice by a non-V beta 8-specific superantigen.
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Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities.
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Adverse effects of constitutively active alpha(1B)-adrenergic receptors after pressure overload in mouse hearts.
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Age-dependent alterations of peritoneal exudate macrophages in autoimmune-prone and autoimmune-resistant mouse strains.
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Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide.
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Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide.
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Alopecia in IL-10-deficient mouse pups is c-kit-dependent and can be triggered by iron deficiency.
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Alteration of pulmonary neuroendocrine cells during epithelial repair of naphthalene-induced airway injury.
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Alterations in inorganic phosphate in mouse hindlimb muscles during limb disuse.
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Alterations of excitatory amino acid receptors in the brain of manganese-treated mice.
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Altered intragraft immune responses and improved renal function in MHC class II-deficient mouse kidney allografts.
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Altered lung gene expression in CCSP-null mice suggests immunoregulatory roles for Clara cells.
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Altered pulmonary response to hyperoxia in Clara cell secretory protein deficient mice.
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Altering and assessing persistence of genetically modified E. coli MG1655 in the large bowel.
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An N-ethyl-N-nitrosourea mutagenesis screen for epigenetic mutations in the mouse.
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An anxiety-like phenotype in mice selectively bred for aggression.
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An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models.
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An imaging-based approach to identify ligands for olfactory receptors.
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An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons.
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Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury.
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Animal models provide insight into psychosomatic factors in diabetes.
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Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites.
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Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation.
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Anti-La antibody production by MRL-1pr/1pr mice. Analysis of fine specificity.
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Anti-TCRβ mAb induces long-term allograft survival by reducing antigen-reactive T cells and sparing regulatory T cells.
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Anti-inflammatory and anti-osteoporotic activities of base-boronated nucleosides and phosphate-boronated nucleotides in rodents.
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Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase.
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Anti-mouse mesangial cell serum induces acute glomerulonephropathy in mice.
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Antibody responses in athymic ('nude') mice implanted with neonatal or adult allogeneic thymus.
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Antimicrobial activity of PLUNC protects against Pseudomonas aeruginosa infection.
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Antineoplastic activity of a series of boron analogues of alpha-amino acids.
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Antinuclear antibodies and nuclear antigens in NZB myeloma ascitic fluids.
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Biosynthesis of renin: multiplicity of active and intermediate forms.
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Body weight is not always a good predictor of longevity in mice.
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Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism.
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Bombesin increases fetal lung growth and maturation in utero and in organ culture.
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Brain tumors in man and animals: report of a workshop.
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CD44--a molecule involved in leukocyte adherence and T-cell activation.
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Calcitonin gene-related peptide (CGRP) in the developing mouse limb.
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Carcinogenicity and toxicity of inhaled nitrobenzene in B6C3F1 mice and F344 and CD rats.
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Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation.
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Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase.
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Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice.
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Cellular requirements for anti-DNA production induced in mice by immunization with bacterial DNA.
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Characteristics of Vibration that Alter Cardiovascular Parameters in Mice.
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Characterization and expression of the complementary DNA encoding rat histidine decarboxylase.
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Characterization and idiotypic analysis of an anti-RNP monoclonal antibody.
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Characterization of a novel human corneal endothelial antigen.
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Characterization of a spontaneous murine astrocytoma and abrogation of its tumorigenicity by cytokine secretion.
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Characterization of glomerular thromboxane receptors in murine lupus nephritis.
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Characterization of monoclonal antibodies with specificity for DNA and the synthetic polypeptide antigen (T,G)-A-L.
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Characterization of the effects of endotoxin on macrophage tumor cell killing.
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Characterization of the insulinotropic potency of polyunsaturated fatty acids.
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Chloroform inhalation exposure conditions necessary to initiate liver toxicity in female B6C3F1 mice.
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Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci.
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Ciliary neurotrophic factor receptor alpha mRNA in NB41A3 neuroblastoma cells: regulation by cAMP.
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Circulating levels of IL-1B+IL-6 cause ER stress and dysfunction in islets from prediabetic male mice.
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Clara cell secretory protein decreases lung inflammation after acute virus infection.
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Clara cell secretory protein deficiency increases oxidant stress response in conducting airways.
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Clara cell secretory protein-deficient mice differ from wild-type mice in inflammatory chemokine expression to oxygen and ozone, but not to endotoxin.
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Clearance of adenovirus-infected hepatocytes by MHC class I-restricted CD4+ CTLs in vivo.
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Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities.
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Cloning genes that encode inducible forms of P-450.
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Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper disks: phenotypic and genotypic analysis of B cell colonies.
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Co-expression of vimentin and cytokeratins in parietal endoderm cells of early mouse embryo.
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Comparison of in vitro and in vivo differentiation of myeloblastic leukemia of the RFM/Un mouse.
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Comparison of pleural responses of rats and hamsters to subchronic inhalation of refractory ceramic fibers.
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Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2.
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Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice.
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Control of expression of insulin resistance and hyperglycemia by different genetic factors in diabetic C57BL/6J mice.
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Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog.
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Cryptococcus neoformans gene involved in mammalian pathogenesis identified by a Caenorhabditis elegans progeny-based approach.
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Cultivation and characterization of cells derived from mouse skin papillomas induced by an initiation-promotion protocol.
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Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung.
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Cyclosporine inhibition of a murine B cell lymphoma.
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Cysteine-tailed class I-binding peptides bind to CpG adjuvant and enhance primary CTL responses.
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Deficits in reproduction and pro-gonadotropin-releasing hormone processing in male Cpefat mice.
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Deletion of Y chromosome sequences located outside the testis determining region can cause XY female sex reversal.
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Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture.
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Detection of the major glycoproteins of Friend leukemia virus (gp71) and the murine mammary tumor virus (gp52) on the surface of mouse cells.
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Diabetic kidney disease in FVB/NJ Akita mice: temporal pattern of kidney injury and urinary nephrin excretion.
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Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis.
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Diacylglycerol kinase ζ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responses.
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Diazoxide restores beta3-adrenergic receptor function in diet-induced obesity and diabetes.
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Differential effects mediated by GABAA receptors in thalamic nuclei in lh/lh model of absence seizures.
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Differential effects of vascular endothelial growth factor receptor-2 inhibitor ZD6474 on circulating endothelial progenitors and mature circulating endothelial cells: implications for use as a surrogate marker of antiangiogenic activity.
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Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo.
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Differential glycemic effects of morphine in diabetic and normal mice.
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Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.
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Disruption of intrathymic CD4-Ia interactions on immature CD4+CD8+ thymocytes results in diminished TCR expression on mature CD8+ T cell progeny.
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Divergent pathways mediate the induction of ANF transgenes in neonatal and hypertrophic ventricular myocardium.
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Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors.
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Dose-dependent effect of melatonin on life span and spontaneous tumor incidence in female SHR mice.
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E2-induced degradation of uterine insulin receptor substrate-2: requirement for an IGF-I-stimulated, proteasome-dependent pathway.
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Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice.
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Effect of basic fibroblast growth factor on angiogenesis and growth of isografted bone: quantitative in vitro-in vivo analysis in mice.
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Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice.
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Effect of fatty acids on insulin release: role of chain length and degree of unsaturation.
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Effect of neuronol on lifespan and development of spontaneous tumors in SAMP-1 mice with genetically accelerated aging.
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Effects of IL-1 on hematopoietic progenitors after myelosuppressive chemoradiotherapy.
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Effects of burn injury, cold stress and cutaneous wound injury on the morphology and energy metabolism of murine brown adipose tissue (BAT) in vivo.
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Effects of maternal nicotine exposure on branching morphogenesis of mouse fetal lung: in vivo and in vitro studies.
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Effects of murine cytomegalovirus infection on the immune response to a tumor allograft.
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Effects of the kinase inhibitor sorafenib on heart, muscle, liver and plasma metabolism in vivo using non-targeted metabolomics analysis.
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Ejaculatory abnormalities in mice with targeted disruption of the gene for heme oxygenase-2.
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Embryonic germ cell lines and their derivation from mouse primordial germ cells.
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Endogenous production of extracellular adenosine by trabecular meshwork cells: potential role in outflow regulation.
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Enhanced growth of small bowel in transgenic mice overexpressing bovine growth hormone.
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Enhancement of endocrine pancreatic secretions by essential fatty acids.
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Enhancement of experimental anaerobic infections by blood, hemoglobin, and hemostatic agents.
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Epidermal growth factor replaces estrogen in the stimulation of female genital-tract growth and differentiation.
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Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis.
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Essential role of LAT in T cell development.
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EuroPhenome: a repository for high-throughput mouse phenotyping data.
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Evaluation of antitussive potential of Jussiaea suffruticosa linn. extract in albino mice.
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Evidence for an immune barrier after in utero hematopoietic-cell transplantation.
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Evidence for the existence of renin in the heart.
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Evidence for two cellular pathways of renin secretion by the mouse submandibular gland.
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Evidence of CNIH3 involvement in opioid dependence.
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Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans.
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Expression of Mls determinants in mice exhibiting the severe combined immunodeficiency (scid) mutation or X-linked immunodeficiency (xid) defect.
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Expression of a murine cytomegalovirus early-late protein in "latently" infected mice.
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Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination.
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Expression of transforming growth factor beta 2 RNA during murine embryogenesis.
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Expression-based assay of an X-linked gene to examine effects of the X-controlling element (Xce) locus.
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Facilitative glucose transporter Glut1 is actively excluded from rod outer segments.
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Fast skeletal muscle-specific expression of a quail troponin I gene in transgenic mice.
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Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging.
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Flow cytometric detection of lymphocyte proliferation in eyes with immunogenic inflammation.
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GABAB receptor-mediated effects in synaptosomes of lethargic (lh/lh) mice.
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GABAB-activated gK+ in thalamic neurons in the lethargic (lh/lh) mouse model of generalized absence seizures.
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Gallbladder glycoprotein secretion in mice with hemolytic anemia and pigment gallstones.
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Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation.
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Gene expression profiles of RAW264.7 macrophages stimulated with preparations of LPS differing in isolation and purity.
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Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans.
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Genetic ablation in transgenic mice with an attenuated diphtheria toxin A gene.
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Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.
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Genetic basis of murine antibacterial defense to streptococcal lung infection.
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Genetic basis of murine responses to hyperoxia-induced lung injury.
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Genetic control of inflammatory arthritis and glomerulonephritis in congenic lpr mice and their F1 hybrids.
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Genetic control of the immune response to nuclease. V. Genetic linkage and strain distribution of anti-nuclease idiotypes.
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Genetic control of the immune response to staphylococcal nuclease. VII. Role of non-H2-linked genes in the control of the anti-nuclease antibody response.
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Genetic control of the immune response to staphylococcal nuclease. VIII. Mapping of genes for antibodies to different antigenic regions of nuclease.
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Genetic dissection of the mouse brain using high-field magnetic resonance microscopy.
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Genetic modifiers and oligogenic inheritance.
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Genetic regulation of glucose phosphate isomerase in mouse oocytes.
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Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice.
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Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.
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Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells.
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Glutathione-mediated preservation and enhancement of isolated perifused islet function.
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Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis.
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H-2K molecules have two different C-termini, one of which is K-region specific.
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H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejection.
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Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4.
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Helix-loop-helix transcription factors E12 and E47 are not essential for skeletal or cardiac myogenesis, erythropoiesis, chondrogenesis, or neurogenesis.
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Heparin binding EGF is necessary for vasospastic response to endothelin.
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High oxygen prevents fetal lethality due to lack of catecholamines.
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High-frequency alloreactive T cells augment effector function of low-frequency CD8+ T-cell responses under CD28/CD154 blockade.
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Hypertension in CB57BL/6J mouse model of non-insulin-dependent diabetes mellitus.
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Hypolipidemic activity of boronated nucleosides and nucleotides in rodents.
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Hypolipidemic activity of tetrakis-mu-(trimethylamine-boranecarboxylato)-bis(trimethylamin e- carboxyborane)-dicopper(II) in rodents and its effect on lipid metabolism.
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Hypoxia modulates nitric oxide-induced regulation of NMDA receptor currents and neuronal cell death.
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ICAM-1 expression in autoimmune encephalitis visualized using magnetic resonance imaging.
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Identification of a congenic mouse line with obesity and body length phenotypes.
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Identification of c-kit-positive cells in the mouse ureter: the interstitial cells of Cajal of the urinary tract.
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Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.
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Idiotypic cross-reaction between MRL monoclonal autoantibodies with different antigen specificity.
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IgG binding of monoclonal anti-nuclear antibodies from MRL-lpr/lpr mice.
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Immunization with the Sm nuclear antigen induces anti-Sm antibodies in normal and MRL mice.
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Immunodominant liver-specific expression suppresses transgene-directed immune responses in murine pompe disease.
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Immunofluorescent analysis of expression of the RNA tumor virus major glycoprotein, gp71, on the surfaces of normal murine cells.
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Immunogenic determinants of a neuropathogenic murine leukemia virus.
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Immunologic control of the ascites of murine adenocarcinoma 755. I. Protection with syngeneic immune serum or lymphoid cells.
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Immunological consequences of transplanting rat insulinomas.
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Impact of genetic background on nephropathy in diabetic mice.
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Impaired second phase insulin response of diabetes-prone C57BL/6J mouse islets.
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In vitro and in vivo investigations for the development of cytostatic methylhydrazones.
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In vitro survival and differentiation of neurons derived from epidermal growth factor-responsive postnatal hippocampal stem cells: inducing effects of brain-derived neurotrophic factor.
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In vivo antigenic modification of tumor cells. I. Introduction of murine leukemia virus antigens on non-virus-producing murine sarcomas.
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In vivo antigenic modification of tumor cells. II. Distribution of virus in sarcoma-bearing mice.
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In vivo antigenic modification of tumor cells. III. Metastatic thymic lymphoma specifically infected by thymotropic retrovirus.
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In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations.
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In vivo models for studying mast cell-dependent responses to bacterial infection.
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In vivo modulation of macrophage tumoricidal activity: enhanced tumor cell killing by peritoneal macrophages from mice given injections of sodium periodate.
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In vivo photoacoustic imaging of transverse blood flow by using Doppler broadening of bandwidth.
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Inactivation of murine xenotropic oncornavirus by normal mouse sera is not immunoglobulin-mediated.
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Increased alkaline phosphatase specific activity in reeler cerebella.
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Increased levels of IgE and autoreactive, polyreactive IgG in wild rodents: implications for the hygiene hypothesis.
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Increasing fructose 2,6-bisphosphate overcomes hepatic insulin resistance of type 2 diabetes.
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Inducible nitric oxide synthase promotes cytokine expression in cardiac allografts but is not required for efficient rejection.
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Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA.
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Induction of immune-mediated glomerulonephritis in normal mice immunized with bacterial DNA.
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Influence of genotype, dose and sex on pruritogen-induced scratching behavior in the mouse.
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Influence of nociception and stress-induced antinociception on genetic variation in isoflurane anesthetic potency among mouse strains.
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Influence of ozone on pentobarbital-induced sleeping time in mice, rats, and hamsters.
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Inhibition of in vitro anti-DNA B-cell responses by cyclosporine.
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Inhibition of murine cytotoxic T lymphocyte activity by a synthetic retroviral peptide and abrogation of this activity by IL.
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Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program.
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Initial testing (stage 1) of the BH3 mimetic ABT-263 by the pediatric preclinical testing program.
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Initial testing (stage 1) of the proteasome inhibitor bortezomib by the pediatric preclinical testing program.
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Initial testing of VNP40101M (Cloretazine) by the pediatric preclinical testing program.
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Initial testing of dasatinib by the pediatric preclinical testing program.
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Insulin in aging and cancer: antidiabetic drug Diabenol as geroprotector and anticarcinogen.
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Interdependence of N nucleotide addition and recombination site choice in V(D)J rearrangement.
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Interferon suppresses pinocytosis but stimulates phagocytosis in mouse peritoneal macrophages: related changes in cytoskeletal organization.
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Interspecies comparison of pharmacokinetic profile and bioavailability of (+/-)-gossypol in male Fischer-344 rats and male B6C3F mice.
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Intrinsic and induced regulation of the age-associated onset of spontaneous experimental autoimmune encephalomyelitis.
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Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles.
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Inverse relationship between splenomegaly and stem cell compartment size in mice treated with nitrogen mustard.
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Investigation of antiestrogenic properties of unleaded gasoline in female mice.
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Involvement of multiple factors in the clonal deletion of self-reactive T cells.
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Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant.
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Kinetics of release of serotonin from isolated secretory granules. I. Amperometric detection of serotonin from electroporated granules.
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Kinetics of release of serotonin from isolated secretory granules. II. Ion exchange determines the diffusivity of serotonin.
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Lactobacillus rhamnosus GG improves outcome in experimental pseudomonas aeruginosa pneumonia: potential role of regulatory T cells.
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Lactoferrin expression in the mouse reproductive tract during the natural estrous cycle: correlation with circulating estradiol and progesterone.
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Left ventricular hypertrophy in ascending aortic stenosis mice: anoikis and the progression to early failure.
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Left ventricular volumes and function in the embryonic mouse heart.
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Lens fiber cell elongation and differentiation is associated with a robust increase in myosin light chain phosphorylation in the developing mouse.
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Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse.
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Local production of TGF beta1 inhibits cerebral edema, enhances TNF-alpha induced apoptosis and improves survival in a murine glioma model.
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Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system.
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Localization of Shaw-related K+ channel genes on mouse and human chromosomes.
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Long- and short-lived murine hematopoietic stem cell clones individually identified with retroviral integration markers.
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Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles.
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Long-term stability of electroenzymatic glucose sensors implanted in mice. An update.
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Loss of atm radiosensitizes multiple p53 null tissues.
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Low plasma leptin in response to dietary fat in diabetes- and obesity-prone mice.
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Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model.
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Macrophage polykaryon formation in vitro by peritoneal cells from mice given injections of sodium periodate.
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Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice.
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Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity.
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Mechanisms of autoantibody production in autoimmune MRL mice.
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Mechanisms of tolerance induced by PG490-88 in a bone marrow transplantation model.
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Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy.
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Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice.
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Metabolomic analysis of insulin resistance across different mouse strains and diets.
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Metastatic prostate cancer in a transgenic mouse.
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MicroRNA genes are frequently located near mouse cancer susceptibility loci.
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Migration of mesonephric cells into the mammalian gonad depends on Sry.
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Mitochondrial malic enzyme in mosaic skeletal muscle of mouse chimeras.
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Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination.
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Mitosis is required for production of murine leukemia virus and structural proteins during de novo infection.
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Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity.
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Models of primary generalized epilepsy.
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Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA.
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Molecular and genetic characterization of a radiation-induced structural rearrangement in mouse chromosome 2 causing mutations at the limb deformity and agouti loci.
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Molecular phenotype of airway side population cells.
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Monoclonal rheumatoid factors from B6-lpr/lpr mice.
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Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines.
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Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis.
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Multivalent cross-linking of membrane Ig sensitizes murine B cells to a broader spectrum of CpG-containing oligodeoxynucleotide motifs, including their methylated counterparts, for stimulation of proliferation and Ig secretion.
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Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo.
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Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence.
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Muscle wasting and interleukin-6-induced atrogin-I expression in the cachectic Apc ( Min/+ ) mouse.
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Mutant mice and neuroscience: recommendations concerning genetic background. Banbury Conference on genetic background in mice.
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Mycophenolate mofetil suppresses autoimmunity and mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus.
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Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury.
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NOV (CCN3) regulation in the growth plate and CCN family member expression in cartilage neoplasia.
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Neem oil inhibits two-cell embryo development and trophectoderm attachment and proliferation in vitro.
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Neonatal W-mutant mice are favorable hosts for tracking development of marked hematopoietic stem cells.
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Nephrotoxicity and hepatotoxicity induced by inhaled bromodichloromethane in wild-type and p53-heterozygous mice.
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Neural induction and patterning in the mouse in the absence of the node and its derivatives.
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Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling.
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Neurodegeneration in the central nervous system of apoE-deficient mice.
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Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.
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Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection.
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Nitric oxide regulation of myocardial contractility and calcium cycling: independent impact of neuronal and endothelial nitric oxide synthases.
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Nitrosylation of blood hemoglobin and renal nonheme proteins in autoimmune MRL-lpr/lpr mice.
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Noninvasively induced degeneration of neocortical pyramidal neurons in vivo: selective targeting by laser activation of retrogradely transported photolytic chromophore.
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Notch-dependent differentiation of adult airway basal stem cells.
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Novel MRI and fluorescent probes responsive to the Factor XIII transglutaminase activity.
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Ontogeny of B lymphocytes. II. Relative rates of appearance of lymphocytes bearing surface immunoglobulin and complement receptors.
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Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A).
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Overexpression of extracellular superoxide dismutase decreases lung injury after exposure to oil fly ash.
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Oxidative stress and inflammation contribute to lung toxicity after a common breast cancer chemotherapy regimen.
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Ozone-induced acute pulmonary injury in inbred mouse strains.
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PG27, an extract of Tripterygium wilfordii hook f, induces antigen-specific tolerance in bone marrow transplantation in mice.
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Paclitaxel-induced neuropathic hypersensitivity in mice: responses in 10 inbred mouse strains.
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Pain modality- and sex-specific effects of COMT genetic functional variants.
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Paternal deletion from Snrpn to Ube3a in the mouse causes hypotonia, growth retardation and partial lethality and provides evidence for a gene contributing to Prader-Willi syndrome.
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Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP.
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Peripheral mobilization of recipient bone marrow-derived endothelial progenitor cells enhances pancreatic islet revascularization and engraftment after intraportal transplantation.
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Permeability of different experimental brain tumor models to horseradish peroxidase.
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Phenylalanine hydroxylase in dilute lethal mice.
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Phorbol diester-induced H2O2 production by peritoneal macrophages. Different H2O2 production by macrophages from normal and BCG-infected mice despite comparable phorbol diester receptors.
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Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity.
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Physiologic role for enhanced renal thromboxane production in murine lupus nephritis.
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Piezo-assisted nuclear transfer affects cloning efficiency and may cause apoptosis.
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Plasma FGF23 levels increase rapidly after acute kidney injury.
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Plasticity of airway cell proliferation and gene expression after acute naphthalene injury.
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Postnatal construction of neural circuitry in the mouse olfactory bulb.
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Pparg-P465L mutation worsens hyperglycemia in Ins2-Akita female mice via adipose-specific insulin resistance and storage dysfunction.
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Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation.
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Prevention of graft-versus-host disease by a novel immunosuppressant, PG490-88, through inhibition of alloreactive T cell expansion.
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Prevention of graft-versus-host disease while preserving graft-versus-leukemia effect after selective depletion of host-reactive T cells by photodynamic cell purging process.
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Production and role of cytokines in the CNS of mice with acute viral encephalomyelitis.
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Prolonged survival of class II transactivator-deficient cardiac allografts.
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Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes.
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Properties of multilamellar liposomes containing 99mTcO4-: effect of distearoylphosphatidylcholine to sphingomyelin ratio.
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Protein patterns of early mouse embryos during development.
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Proteolytic activity and immunogenicity of oral bromelain within the gastrointestinal tract of mice.
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Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles.
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Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes.
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RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance.
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Rapamycin suppression of host-versus-graft and graft-versus-host disease in MHC-mismatched rats.
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Receptors for immunoglobulin and complement on mouse leukemias and lymphomas.
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Regulation of E2A gene expression in B-lymphocyte development.
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Regulation of IgE synthesis: introduction.
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Regulation of flt-1 expression during mouse embryogenesis suggests a role in the establishment of vascular endothelium.
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Regulation of local and metastatic host-mediated anti-tumour mechanisms by L-selectin and intercellular adhesion molecule-1.
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Regulation of sodium balance and blood pressure by the AT(1A) receptor for angiotensin II.
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Regulation of the anti-Sm autoantibody response in systemic lupus erythematosus mice by monoclonal anti-Sm antibodies.
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Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis.
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Regulatory genes linked to the albino locus in the mouse confer competence for inducible expression on the structural gene encoding serine dehydratase.
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Renal tubular cell expression of MHC class II (I-Eb) is insufficient to initiate immune injury in a transgenic kidney transplant model.
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Rescue of cytotoxic function in the CD8alpha knockout mouse by removal of MHC class II.
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Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions.
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Retinoic acid induction and regional differentiation prefigure olfactory pathway formation in the mammalian forebrain.
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Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis.
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Revisiting lessons from the C57BL/6J mouse.
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Role for hedgehog pathway in regulating growth and function of invariant NKT cells.
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Rous sarcoma virus-induced tumours in mice. II. Contribution of H-2 and non-H-2 alloantigen barriers to tumour immunogenicity in vivo.
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Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways.
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Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes.
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Sequence elements required for transcriptional activity of the human myoglobin promoter in intact myocardium.
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Serine/threonine phosphorylation regulates HNF-4alpha-dependent redox-mediated iNOS expression in hepatocytes.
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Sex differences in ethanol-related behaviors in genetically defined murine stocks.
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Species differences in cardiac thyroid hormone receptor isoforms protein abundance.
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Specific transforming potential of oncogenes encoding protein-tyrosine kinases.
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Specificity analysis of monoclonal anti-DNA antibodies from B6-lpr/lpr mice.
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Specificity analysis of monoclonal anti-DNA antibodies.
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Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4.
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Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA.
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Stochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cells.
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Structural features of nephritogenic lupus autoantibodies.
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Structure of the genes encoding the CD19 antigen of human and mouse B lymphocytes.
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Studies on the mechanism and specificity of the effect of the synthetic random copolymer GLAT on graft-versus-host disease.
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Successful tumour immunotherapy: possible role of antibodies to anti-inflammatory factors produced by neoplasms.
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Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice.
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Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance.
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Synergy between tumor immunotherapy and antiangiogenic therapy.
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Targeted inhibition of beta-adrenergic receptor kinase-1-associated phosphoinositide-3 kinase activity preserves beta-adrenergic receptor signaling and prolongs survival in heart failure induced by calsequestrin overexpression.
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Targeting molecular and cellular inhibitory mechanisms for improvement of antitumor memory responses reactivated by tumor cell vaccine.
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Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers.
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Tenascin is induced at implantation sites in the mouse uterus and interferes with epithelial cell adhesion.
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Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction.
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Testosterone regulates cell proliferation in aggressive fibromatosis (desmoid tumour).
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The Aspergillus fumigatus P-type Golgi apparatus Ca2+/Mn2+ ATPase PmrA is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis.
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The HMG-CoA reductase inhibitor pravastatin stimulates insulin secretion through organic anion transporter polypeptides.
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The IFN pregnancy recognition hormone IFN-tau blocks both development and superantigen reactivation of experimental allergic encephalomyelitis without associated toxicity.
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The acute toxicity of drugs acting at cholinoceptive sites and twenty-four hour rhythms in brain acetylcholine.
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The androgen-binding protein gene is expressed in CD1 mouse testis.
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The anti-La response of a single MRL/Mp-lpr/lpr mouse: specificity for DNA and VH gene usage.
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The binding of 7,12-dimethylbenz(A)anthracene to replicating and non-replicating DNA in cell culture.
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The binding of fucose-containing glycoproteins by hepatic lectins. Re-examination of the clearance from blood and the binding to membrane receptors and pure lectins.
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The clearance of a monoclonal anti-DNA antibody following administration of DNA in normal and autoimmune mice.
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The clearance of human fibrinogen fragments X and Y in mice: a process mediated by the fragment D receptor.
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The fate of effector CD8 T cells in vivo is controlled by the duration of antigen stimulation.
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The fine specificity of anti-La antibodies induced in mice by immunization with recombinant human La autoantigen.
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The immune response to staphylococcal nuclease: a probe of cellular and humoral antigen-specific receptors.
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The induction of tolerance and suppression in autoimmune MRL mice using hapten-modified self.
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The influence of Yaa on anti-DNA responses of B6-lpr mice.
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The influence of the lpr gene on B cell activation: differential antibody expression in lpr congenic mouse strains.
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The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.
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The production and characterization of murine monoclonal antibodies to human Gadd45 raised against a recombinant protein.
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The role of CD4-Lck in T-cell receptor antagonism: evidence for negative signaling.
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The role of GABAB receptor activation in absence seizures of lethargic (lh/lh) mice.
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The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: differential effects in rats and mice.
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The role of new vessels and macrophages in the development and resolution of edema following a cortical freeze lesion in the mouse.
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Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture.
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Three-dimensional structure of the developing mouse genital ridge.
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Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.
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Thromboxane augmentation of alloreactive T cell function.
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Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice.
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Tnni3k modifies disease progression in murine models of cardiomyopathy.
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Tracheal ligation increases cell proliferation but decreases surfactant protein in fetal murine lungs in vitro.
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Transferrin receptor is necessary for development of erythrocytes and the nervous system.
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Transgenic expression of pancreatic secretory trypsin inhibitor-I ameliorates secretagogue-induced pancreatitis in mice.
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Transgenic indicator mice for studying activated retinoic acid receptors during development.
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Transgenic mice expressing the p75 CCAAT-displacement protein/Cut homeobox isoform develop a myeloproliferative disease-like myeloid leukemia.
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Transgenic tubular cell expression of class II is insufficient to initiate immune renal injury.
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Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia.
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Tryptophan hydroxylase-2 controls brain serotonin synthesis.
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Tumor cells cotransduced with B7.1 and gamma-IFN induce effective rejection of established parental tumor.
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Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand.
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Tumor-dendritic cell fusion as a basis for cancer immunotherapy.
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Tumorigenic cell culture lines from a spontaneous VM/Dk murine astrocytoma (SMA).
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Two-photon molecular excitation imaging of Ca2+ transients in Langendorff-perfused mouse hearts.
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Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages.
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Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene.
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Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice.
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Velocity differences between L- and P-selectin-dependent neutrophil rolling in venules of mouse cremaster muscle in vivo.
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Very-long-chain acyl-coenzyme a dehydrogenase deficiency in mice.
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Viral infection-homograft interactions in a murine model.
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Vital imaging of glomeruli in the mouse olfactory bulb.
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X inactivation analysis and DNA methylation studies of the ubiquitin activating enzyme E1 and PCTAIRE-1 genes in human and mouse.
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Zinc inhibits turnover of labile mRNAs in intact cells.
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c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice.
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Keywords of People
-
Choi, Steven Sok,
Associate Professor of Medicine,
Medicine, Gastroenterology
-
Erickson, Harold Paul,
James B. Duke Distinguished Professor of Cell Biology,
Biomedical Engineering
-
Gunn, Michael Dee,
Professor of Medicine,
Immunology
-
Hogan, Brigid L. M.,
George Barth Geller Distinguished Professor,
Cell Biology
-
Johnson, G. Allan,
Charles E. Putman University Distinguished Professor of Radiology,
Physics
-
Juvvadi, Praveen Rao,
Assistant Professor in Pediatrics,
Pediatrics, Infectious Diseases
-
Kelsoe, Garnett H.,
James B. Duke Distinguished Professor of Immunology,
Immunology
-
Sampson, John Howard,
Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine,
Immunology
-
Steinbach, William J.,
Samuel L. Katz Distinguished Professor of Pediatrics,
Duke Innovation & Entrepreneurship
-
Tsalik, Ephraim,
Associate Professor of Medicine,
Molecular Genetics and Microbiology
-
Warner, David Samuel,
Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine,
Neurobiology