Mice, Neurologic Mutants
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Subject Areas on Research
- 440-kD ankyrinB: structure of the major developmentally regulated domain and selective localization in unmyelinated axons.
- ALSUntangled No. 34: GM604.
- ALSUntangled No. 35: Hyperbaric Oxygen Therapy.
- Age-related congophilic inclusions in the brains of apolipoprotein E-deficient mice.
- Age-related relationship between mRNA expression of GABA(B) receptors and calcium channel beta4 subunits in cacnb4lh mice.
- Alteration of IGF system gene expression during the postnatal development of pcd mice.
- An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons.
- ApoER2 function in the establishment and maintenance of retinal synaptic connectivity.
- Apolipoprotein E and Reelin ligands modulate tau phosphorylation through an apolipoprotein E receptor/disabled-1/glycogen synthase kinase-3beta cascade.
- Applicability and limitations of MR tracking of neural stem cells with asymmetric cell division and rapid turnover: the case of the shiverer dysmyelinated mouse brain.
- Decreased (45)Ca(2)(+) uptake in P/Q-type calcium channels in homozygous lethargic (Cacnb4lh) mice is associated with increased beta3 and decreased beta4 calcium channel subunit mRNA expression.
- Decreased IGF-I gene expression during the apoptosis of Purkinje cells in pcd mice.
- Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice.
- Excitatory but not inhibitory synaptic transmission is reduced in lethargic (Cacnb4(lh)) and tottering (Cacna1atg) mouse thalami.
- Glutamate decarboxylase isoforms in thalamic nuclei in lethargic mouse model of absence seizures.
- Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion.
- Graft-induced restoration of function in hereditary cerebellar ataxia.
- Grafted cerebellar cells in a mouse model of hereditary ataxia express IGF-I system genes and partially restore behavioral function.
- High-field (9.4 T) MRI of brain dysmyelination by quantitative mapping of magnetic susceptibility.
- Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice.
- Increased number of GABAB receptors in the lethargic (lh/lh) mouse model of absence epilepsy.
- Intracellular trafficking of histone deacetylase 4 regulates neuronal cell death.
- Kindling and associated mossy fibre sprouting are not affected in mice deficient of NGFI-A/NGFI-B genes.
- Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine.
- Magnetic susceptibility anisotropy of human brain in vivo and its molecular underpinnings.
- Mechanisms of increased hippocampal excitability in the Mashl+/- mouse model of Na+ /K+ -ATPase dysfunction.
- Neuroanatomical phenotypes in the reeler mouse.
- Orphan nuclear receptors in T lymphocyte development.
- Rescue of neurological deficits in a mouse model for Angelman syndrome by reduction of alphaCaMKII inhibitory phosphorylation.
- Sodium channel density in hypomyelinated brain increased by myelin basic protein gene deletion.
- Stargazing nets new calcium channel subunit.
- Studies of the lethargic (lh/lh) mouse model of absence seizures: regulatory mechanisms and identification of the lh gene.
- The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus.
- The role of GABAB mechanisms in animal models of absence seizures.
- Tracking brain volume changes in C57BL/6J and ApoE-deficient mice in a model of neurodegeneration: a 5-week longitudinal micro-MRI study.
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Keywords of People
- Bennett, Vann, George B. Geller Distinguished Professor for Research in Molecular Biology in the School of Medicine, Duke Cancer Institute
- Hogan, Brigid L. M., George Barth Geller Distinguished Professor, Cell Biology
- Johnson, G. Allan, Charles E. Putman University Distinguished Professor of Radiology, Physics
- Warner, David Samuel, Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology