Mice, Obese
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Subject Areas on Research
- A futile metabolic cycle activated in adipocytes by antidiabetic agents.
- A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis.
- Accurate temperature imaging based on intermolecular coherences in magnetic resonance.
- Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease.
- Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice.
- Adrenoceptors, uncoupling proteins, and energy expenditure.
- Alprazolam reduces stress hyperglycemia in ob/ob mice.
- Animal models of steatohepatitis.
- Animal models of steatosis.
- Bacterial lipopolysaccharide induces uncoupling protein-2 expression in hepatocytes by a tumor necrosis factor-alpha-dependent mechanism.
- Behavioral manipulation of the diabetic phenotype in ob/ob mice.
- Carnitine revisited: potential use as adjunctive treatment in diabetes.
- Chromosomal assignment of the murine Gi alpha and Gs alpha genes. Implications for the obese mouse.
- Classically conditioned enhancement of hyperinsulinemia in the ob/ob mouse.
- Classically conditioned hyperglycemia in the obese mouse.
- Conditional Macrophage Depletion Increases Inflammation and Does Not Inhibit the Development of Osteoarthritis in Obese Macrophage Fas-Induced Apoptosis-Transgenic Mice.
- Depressed expression of adipocyte beta-adrenergic receptors is a common feature of congenital and diet-induced obesity in rodents.
- Diet-induced obese mice retain endogenous leptin action.
- Differential glycemic effects of morphine in diabetic and normal mice.
- Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice.
- Disrupted signaling and inhibited regeneration in obese mice with fatty livers: implications for nonalcoholic fatty liver disease pathophysiology.
- Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation.
- Effect of obesity on pulmonary inflammation induced by acute ozone exposure: role of interleukin-6.
- Effect of the monoamine oxidase inhibitors clorgyline and pargyline on the hyperphagia of obese mice.
- Exaggerated peripheral responses to catecholamines contributes to stress-induced hyperglycemia in the ob/ob mouse.
- Fatty liver vulnerability to endotoxin-induced damage despite NF-kappaB induction and inhibited caspase 3 activation.
- Fusion of fibroblast growth factor 21 to a thermally responsive biopolymer forms an injectable depot with sustained anti-diabetic action.
- Gut microbiota from twins discordant for obesity modulate metabolism in mice.
- Hepatic accumulation of Hedgehog-reactive progenitors increases with severity of fatty liver damage in mice.
- Hepatic fibrogenesis requires sympathetic neurotransmitters.
- Hepatic hyperplasia in noncirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition?
- Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression.
- Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.
- In vivo NMR detection of diet-induced changes in adipose tissue composition.
- In vivo brown adipose tissue detection and characterization using water-lipid intermolecular zero-quantum coherences.
- Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase.
- Interleukin-15 increases hepatic regenerative activity.
- Is omega-3 key to unlocking inflammation in obesity?
- Leptin opposes insulin's effects on fatty acid partitioning in muscles isolated from obese ob/ob mice.
- Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway.
- Leptin regulates proinflammatory immune responses.
- Leptin selectively augments thymopoiesis in leptin deficiency and lipopolysaccharide-induced thymic atrophy.
- Loss of pericyte smoothened activity in mice with genetic deficiency of leptin.
- M1 polarization bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in obese mice.
- Metabolic and functional impairment of CD8+ T cells from the lungs of influenza-infected obese mice.
- Metformin reverses fatty liver disease in obese, leptin-deficient mice.
- Mitochondrial adaptations to obesity-related oxidant stress.
- Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver.
- Muscarinic stimulation and antagonism and glucoregulation in nondiabetic and obese hyperglycemic mice.
- NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment.
- Naltrexone potentiates glycemic responses during stress and epinephrine challenge in genetically obese mice.
- Nonalcoholic fatty liver disease: implications for alcoholic liver disease pathogenesis.
- Norepinephrine induces hepatic fibrogenesis in leptin deficient ob/ob mice.
- Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis.
- Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion.
- Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease.
- Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver disease.
- Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis.
- Pharmacologic manipulation of ob expression in a dietary model of obesity.
- Pharmacological antagonism of the incretin system protects against diet-induced obesity.
- Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
- Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss.
- Stress and diabetes mellitus.
- The role of motor activity in diet-induced obesity in C57BL/6J mice.
- Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue.
- Weight Loss and/or Sulindac Mitigate Obesity-associated Transcriptome, Microbiome, and Protumor Effects in a Murine Model of Colon Cancer.
- Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.
- Wound healing with topical BRAF inhibitor therapy in a diabetic model suggests tissue regenerative effects.
- Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program.
- l-Citrulline supplementation improves glucose and exercise tolerance in obese male mice.
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Keywords of People
- Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology