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Subject Areas on Research
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A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity.
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Activation of protein kinase C by oleic acid. Determination and analysis of inhibition by detergent micelles and physiologic membranes: requirement for free oleate.
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Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug.
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Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia.
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An assessment of the effects of shell cross-linked nanoparticle size, core composition, and surface PEGylation on in vivo biodistribution.
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An electron spin resonance study of cholestane spin label in aqueous mixtures of biliary lipids.
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Arachidonate and related unsaturated fatty acids selectively inactivate the guanine nucleotide-binding regulatory protein, Gz.
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Bio-inspired synthesis of hybrid silica nanoparticles templated from elastin-like polypeptide micelles.
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Biodegradable polyphosphoester micelles for gene delivery.
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Cell-directed assembly of lipid-silica nanostructures providing extended cell viability.
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Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy.
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Cyclopamine-loaded core-cross-linked polymeric micelles enhance radiation response in pancreatic cancer and pancreatic stellate cells.
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Cytosolic delivery of macromolecules 4. Head group-dependent membrane permeabilization by pH-sensitive detergents.
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Disc formation in cholesterol-free liposomes during phase transition.
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Divorcing folding from function: how acylation affects the membrane-perturbing properties of an antimicrobial peptide.
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Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency.
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Enzymatic polymerization of high molecular weight DNA amphiphiles that self-assemble into star-like micelles.
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Exchange of monooleoylphosphatidylcholine as monomer and micelle with membranes containing poly(ethylene glycol)-lipid.
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Extrinsic pathway proteolytic activity.
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Functional Modification of Silica through Enhanced Adsorption of Elastin-Like Polypeptide Block Copolymers.
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Functionalized micellar assemblies prepared via block copolymers synthesized by living free radical polymerization upon peptide-loaded resins.
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Fusions of elastin-like polypeptides to pharmaceutical proteins.
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Genetically Encoding Albumin Binding into Chemotherapeutic-loaded Polypeptide Nanoparticles Enhances Their Antitumor Efficacy.
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Harnessing the power of cell-penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents.
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In vivo tumor targeting by a NGR-decorated micelle of a recombinant diblock copolypeptide.
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Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy.
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Log-rolling micelles in sheared amphiphilic thin films.
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Micellar Self-Assembly of Recombinant Resilin-/Elastin-Like Block Copolypeptides.
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Modulation of the binding of signal peptides to lipid bilayers by dipoles near the hydrocarbon-water interface.
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Molecular umbrella-amphotericin B conjugates.
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Morphing low-affinity ligands into high-avidity nanoparticles by thermally triggered self-assembly of a genetically encoded polymer.
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N-terminal domain of Avena phytochrome: interactions with sodium dodecyl sulfate micelles and N-terminal chain truncated phytochrome.
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NIR-emissive PEG-b-TCL micelles for breast tumor imaging and minimally invasive pharmacokinetic analysis.
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Noncanonical self-assembly of highly asymmetric genetically encoded polypeptide amphiphiles into cylindrical micelles.
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Phase Behavior and Self-Assembly of Perfectly Sequence-Defined and Monodisperse Multiblock Copolypeptides.
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Phospholipid-dextran with a single coupling point: a useful amphiphile for functionalization of nanomaterials.
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Photocontrolled micellar aggregation of amphiphilic DNA-azobenzene conjugates.
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Polymersomes: a new multi-functional tool for cancer diagnosis and therapy.
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Prediction of solvent-induced morphological changes of polyelectrolyte diblock copolymer micelles.
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Preparation and characterization of unilamellar vesicles from cholate-phospholipid micelle treated with cholestyramine.
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Protein structures in SDS micelle-protein complexes.
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Quantitative Mapping of the Spatial Distribution of Nanoparticles in Endo-Lysosomes by Local pH.
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Radioiodinated ganglioside GM1: a potential tool for the investigation of ganglioside function in vivo.
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Recombinant acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner.
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Reconstitution of the beta-adrenergic receptor.
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Ring-opening polymerization of prodrugs: a versatile approach to prepare well-defined drug-loaded nanoparticles.
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Salt Responsive Morphologies of ssDNA-Based Triblock Polyelectrolytes in Semi-Dilute Regime: Effect of Volume Fractions and Polyelectrolyte Length.
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Self-assembly of monodisperse oligonucleotide-elastin block copolymers into stars and compound micelles.
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Self-assembly of ordered nanowires in biological suspensions of single-wall carbon nanotubes.
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Simultaneous delivery of siRNA and paclitaxel via a "two-in-one" micelleplex promotes synergistic tumor suppression.
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Supramolecular nanomimetics: replication of micelles, viruses, and other naturally occurring nanoscale objects.
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Surfactant solvation effects and micelle formation in ionic liquids.
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Temperature triggered self-assembly of polypeptides into multivalent spherical micelles.
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The Weak Link: Optimization of the Ligand-Nanoparticle Interface To Enhance Cancer Cell Targeting by Polymer Micelles.
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The actin-binding protein profilin binds to PIP2 and inhibits its hydrolysis by phospholipase C.
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The major allergen from birch tree pollen, Bet v 1, binds and permeabilizes membranes.
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The role of cavitation in acoustically activated drug delivery.
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Thermally responsive polymer-nanoparticle composites for biomedical applications.
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Thermally responsive polymeric micellar nanoparticles self-assembled from cholesteryl end-capped random poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide): synthesis, temperature-sensitivity, and morphologies.
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Triple stimulus-responsive polypeptide nanoparticles that enhance intratumoral spatial distribution.
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Unexpected multivalent display of proteins by temperature triggered self-assembly of elastin-like polypeptide block copolymers.
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Use of SDS micelles to stabilize a ternary intermediate in the reaction of ferrioxamine B and 1,10-phenanthroline.