Microelectrodes

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  Subject Areas on Research

  • A Refined Neuronal Population Measure of Visual Attention. 
  • A bio-friendly and economical technique for chronic implantation of multiple microelectrode arrays. 
  • A biophysical model for cardiac microimpedance measurements. 
  • A brain-to-brain interface for real-time sharing of sensorimotor information. 
  • A comparison of chemical and electrical synaptic transmission between single sensory cells and a motoneurone in the central nervous system of the leech. 
  • A high-density, high-channel count, multiplexed μECoG array for auditory-cortex recordings. 
  • A low power multichannel analog front end for portable neural signal recordings. 
  • A low-cost, multiplexed μECoG system for high-density recordings in freely moving rodents. 
  • A low-cost, scalable, current-sensing digital headstage for high channel count μECoG. 
  • A multichannel telemetry system for single unit neural recordings. 
  • A multimodal micro-optrode combining field and single unit recording, multispectral detection and photolabeling capabilities. 
  • A new approach for resolution of complex tissue impedance spectra in hearts. 
  • A real-time spike classification method based on dynamic time warping for extracellular enteric neural recording with large waveform variability. 
  • A regenerative microchannel device for recording multiple single-unit action potentials in awake, ambulatory animals. 
  • A screw microdrive for adjustable chronic unit recording in monkeys. 
  • A simulation study of information transmission by multi-unit microelectrode recordings. 
  • Activating function of needle electrodes in anisotropic tissue. 
  • An analysis of the effects of acetylcholine on conduction and refractoriness in the rabbit sinus node. 
  • Analysis of potential shifts associated with recurrent spreading depression and prolonged unstable spreading depression induced by microdialysis of elevated K+ in hippocampus of anesthetized rats. 
  • Anatomical identification of extracellularly recorded cells in large-scale multielectrode recordings. 
  • Application of neurosonography to experimental physiology. 
  • Asymmetry of neuronal activity during extracellular microelectrode recording from left and right human temporal lobe neocortex during rhyming and line-matching. 
  • Attachment of gold nanoparticles to glassy carbon electrode and its application for the direct electrochemistry and electrocatalytic behavior of hemoglobin. 
  • Biomechanical analysis of silicon microelectrode-induced strain in the brain. 
  • Brain-machine interfaces: past, present and future. 
  • Chronic in vivo multi-circuit neurophysiological recordings in mice. 
  • Cocaine acts on accumbens monoamines and locomotor behavior via a 5-HT2A/2C receptor mechanism as shown by ketanserin: 24-h follow-up studies. 
  • Collision of excitation waves in the dog Purkinje system. Extracellular identification. 
  • Colloid chemical approach to nanoelectrode ensembles with highly controllable active area fraction. 
  • Combining 'caged-dopamine' photolysis with fast-scan cyclic voltammetry to assess dopamine clearance and release autoinhibition in vitro. 
  • Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents. 
  • Cone contributions to cat retinal ganglion cell receptive fields. 
  • Construction of a very high-density extracellular electrode array. 
  • Cortical imaging: capturing the moment. 
  • Current density distributions, field distributions and impedance analysis of segmented deep brain stimulation electrodes. 
  • Detection of hydrazine, methylhydrazine and isoniazid by capillary electrophoresis with a 4-pyridyl hydroquinone self-assembled microdisk platinum electrode. 
  • Development of high resolution, multiplexed electrode arrays: Opportunities and challenges. 
  • Development of the single microelectrode current and voltage clamp for central nervous system neurons. 
  • Differential corticostriatal plasticity during fast and slow motor skill learning in mice. 
  • Differential metabolic and electrical activity in the somatic sensory cortex of juvenile and adult rats. 
  • Differential quantal release of histamine and 5-hydroxytryptamine from mast cells of vesicular monoamine transporter 2 knockout mice. 
  • Droplet Size-Aware High-Level Synthesis for Micro-Electrode-Dot-Array Digital Microfluidic Biochips. 
  • Dynamic and multimodal responses of gustatory cortical neurons in awake rats. 
  • Dynamically Timed Stimulation of Corticolimbic Circuitry Activates a Stress-Compensatory Pathway. 
  • Dynamics of population response to changes of motion direction in primary visual cortex. 
  • EFFECTS OF LOW-INTENSITY MICROWAVES ON ISOLATED NEURONS. 
  • Effect of cocaine, nomifensine, GBR 12909 and WIN 35428 on carbon fiber microelectrode sensitivity for voltammetric recording of dopamine. 
  • Effect of electrode surface area on thresholds for AC stimulation and ventricular fibrillation. 
  • Effects of micro-iontophoretic administration of magnesium and calcium on neurones in the central nervous system of cats. 
  • Effects of monophasic and biphasic shocks on action potentials during ventricular fibrillation in dogs. 
  • Electrical inhibition of lens epithelial cell proliferation: an additional factor in secondary cataract? 
  • Electrochemical detector based on sol-gel-derived carbon composite material for capillary electrophoresis microchips. 
  • Electrode systems for measuring cardiac impedances using optical transmembrane potential sensors and interstitial electrodes--theoretical design. 
  • Electrophysiological correlates of secretion in normal human parathyroid cells. 
  • Electrophysiology of methyl mercury poisoning. 
  • Electrophysiology of neuroglia. 
  • Ensemble recordings of human subcortical neurons as a source of motor control signals for a brain-machine interface. 
  • Evaluation of BA1112 rhabdomyosarcoma oxygenation with microelectrodes, optical spectrophotometry, radiosensitivity, and magnetic resonance spectroscopy. 
  • Experience-dependent plasticity of rat barrel cortex: redistribution of activity across barrel-columns. 
  • Extracellular chloride and the maintenance of spontaneous epileptiform activity in rat hippocampal slices. 
  • Extracellular potentials related to intracellular action potentials in the dog Purkinje system. 
  • Extraction force and cortical tissue reaction of silicon microelectrode arrays implanted in the rat brain. 
  • Failure to suppress low-frequency neuronal oscillatory activity underlies the reduced effectiveness of random patterns of deep brain stimulation. 
  • Fast modulation of prefrontal cortex activity by basal forebrain noncholinergic neuronal ensembles. 
  • Feasibility of cardiac microimpedance measurement using multisite interstitial stimulation. 
  • Finite element analysis of the current-density and electric field generated by metal microelectrodes. 
  • Flexible, foldable, actively multiplexed, high-density electrode array for mapping brain activity in vivo. 
  • High-resolution intracellular recordings using a real-time computational model of the electrode. 
  • High-sensitivity rod photoreceptor input to the blue-yellow color opponent pathway in macaque retina. 
  • High-throughput cardiac safety evaluation and multi-parameter arrhythmia profiling of cardiomyocytes using microelectrode arrays. 
  • Highly selective water channel activity measured by voltage clamp: analysis of planar lipid bilayers reconstituted with purified AqpZ. 
  • Hypotonic exposure enhances synaptic transmission and triggers spreading depression in rat hippocampal tissue slices. 
  • Hypoxia-induced catecholamine secretion in isolated newborn rat adrenal chromaffin cells is mimicked by inhibition of mitochondrial respiration. 
  • Implications of chronic daily anti-oxidant administration on the inflammatory response to intracortical microelectrodes. 
  • In vitro assessment of long-term reliability of low-cost μECoG arrays. 
  • In vitro model of glial scarring around neuroelectrodes chronically implanted in the CNS. 
  • Integrated circuit amplifiers for multi-electrode intracortical recording. 
  • Interstitial space, electrical resistance and ion concentrations during hypotonia of rat hippocampal slices. 
  • Intracellular Neural Recording with Pure Carbon Nanotube Probes. 
  • Intracellular recording from dopamine neurons in the substantia nigra: double labelling for identification of projection site and morphological features. 
  • Intrinsic optical signals in rat hippocampal slices during hypoxia-induced spreading depression-like depolarization. 
  • Ion-selective microelectrodes and excitable tissue. 
  • Ischemic depolarization during halothane-nitrous oxide and isoflurane-nitrous oxide anesthesia. An examination of cerebral blood flow threshold and times to depolarization. 
  • Kinetics of release of serotonin from isolated secretory granules. I. Amperometric detection of serotonin from electroporated granules. 
  • Lasting neuron depression induced by high potassium and its prevention by low calcium and NMDA receptor blockade. 
  • Lifetime enhancement of ultrasmall fluorescent liquid polymeric film based optodes by diffusion-induced self-recovery after photobleaching. 
  • Manipulation of intra- and extracellular pH in spontaneous canine tumours by use of hyperglycaemia. 
  • Metabolic responses differentiate between interictal, ictal and persistent epileptiform activity in intact, immature hippocampus in vitro. 
  • Microelectrode study of the genesis of the monophasic action potential by contact electrode technique. 
  • Microiontophoretic studies of the effects of L-proline on neurons in the mammalian central nervous system. 
  • Modularity of motor output evoked by intraspinal microstimulation in cats. 
  • Monte Carlo methods for localization of cones given multielectrode retinal ganglion cell recordings. 
  • N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator. 
  • NADH fluorescence and [K+]o changes during hippocampal electrical stimulation. 
  • Nanoscale laminin coating modulates cortical scarring response around implanted silicon microelectrode arrays. 
  • Nanoscale neuro-integrative coatings for neural implants. 
  • New technique for capillary electrophoresis directly coupled with end-column electrochemiluminescence detection. 
  • Non-invasive laser microsurgery selectively damages populations of labeled mouse neurons: dependence on incident laser dose and absorption. 
  • Osmotic-hypertensive opening of the blood-brain barrier in rats does not necessarily provide access for potassium to cerebral interstitial fluid. 
  • Oxygen microelectrode response to oxygen pressures up to 15 ATA. 
  • Patient-specific anatomical model for deep brain stimulation based on 7 Tesla MRI. 
  • Peripheral nerve electrical stimulation. 
  • Physiological organization of layer 4 in macaque striate cortex. 
  • Polarized expression of cAMP-activated chloride channels in isolated epithelial cells. 
  • Primate reaching cued by multichannel spatiotemporal cortical microstimulation. 
  • Quantitation of in vivo measurements with carbon fiber microelectrodes. 
  • Quantitative determination of the partial oxygen pressure in the vitrectomized rabbit eye in vivo using 19F NMR. 
  • Relating extracellular potentials and their derivatives to anisotropic propagation at a microscopic level in human cardiac muscle. Evidence for electrical uncoupling of side-to-side fiber connections with increasing age. 
  • Responses of Purkinje cells in the oculomotor vermis of monkeys during smooth pursuit eye movements and saccades: comparison with floccular complex. 
  • Responses of intraparietal neurons to saccadic targets and visual distractors. 
  • Retinal oxygenation and laser treatment in patients with diabetic retinopathy. 
  • Reversible inactivation of pSTS suppresses social gaze following in the macaque (Macaca mulatta). 
  • Scalable Device for Automated Microbial Electroporation in a Digital Microfluidic Platform. 
  • Selective microstimulation of central nervous system neurons. 
  • Simultaneous optical recording of membrane potential and intracellular calcium from brain slices. 
  • Soluble factor effects on glial cell reactivity at the surface of gel-coated microwires. 
  • Somatic innervation of the feline lower urinary tract. 
  • Song decrystallization in adult zebra finches does not require the song nucleus NIf. 
  • Spatial heterogeneity of restitution properties and the onset of alternans. 
  • Spatiotemporal memory is an intrinsic property of networks of dissociated cortical neurons. 
  • Spatiotemporal properties of layer V neurons of the rat primary somatosensory cortex. 
  • Spinal sensory projection neuron responses to spinal cord stimulation are mediated by circuits beyond gate control. 
  • Spontaneous cortical activity in awake monkeys composed of neuronal avalanches. 
  • Stimulus onset quenches neural variability: a widespread cortical phenomenon. 
  • Structural characteristics of gap junctions. I. Channel number in coupled and uncoupled conditions. 
  • Surprise signals in anterior cingulate cortex: neuronal encoding of unsigned reward prediction errors driving adjustment in behavior. 
  • Susceptibility-enhanced 3-Tesla T1-weighted spoiled gradient echo of the midbrain nuclei for guidance of deep brain stimulation implantation. 
  • Temporal excitation properties of paresthesias evoked by thalamic microstimulation. 
  • The effect of changing extracellular potassium concentration on synaptic transmission in isolated spinal cords. 
  • The effect of contractile activity on fibrillation and extrajunctional acetylcholine-sensitivity in rat muscle maintained in organ culture. 
  • The role of the frontal pursuit area in learning in smooth pursuit eye movements. 
  • The upregulation of specific interleukin (IL) receptor antagonists and paradoxical enhancement of neuronal apoptosis due to electrode induced strain and brain micromotion. 
  • Tuning for spatiotemporal frequency and speed in directionally selective neurons of macaque striate cortex. 
  • Utility of remote wireless pressure sensing for endovascular leak detection after endovascular thoracic aneurysm repair. 
  • Ventral cochlear nucleus responses to contralateral sound are mediated by commissural and olivocochlear pathways. 
  • Virtual active touch using randomly patterned intracortical microstimulation. 
  • Visual and saccade-related activity in macaque posterior cingulate cortex. 
  • Voltammetric and mathematical evidence for dual transport mediation of serotonin clearance in vivo. 
  • Wireless Cortical Brain-Machine Interface for Whole-Body Navigation in Primates. 
  • meaRtools: An R package for the analysis of neuronal networks recorded on microelectrode arrays. 
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  Keywords of People

  • Charles, Hal Cecil, Associate Professor of Radiology, Radiology
  • Chen, Nan-kuei, Adjunct Associate Professor in the Department of Radiology, Radiology
  • Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology