Micromanipulation

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  Subject Areas on Research

  • A method to replicate the microstructure of heart tissue in vitro using DTMRI-based cell micropatterning. 
  • Dynamic control and quantification of bacterial population dynamics in droplets. 
  • Dynamics of neutrophil membrane compliance and microstructure probed with a micropipet-based piconewton force transducer. 
  • Elastic response, buckling, and instability of microtubules under radial indentation. 
  • Embryo dissociation, cell isolation, and cell reassociation. 
  • Estimates of echo correlation and measurement bias in acoustic radiation force impulse imaging. 
  • Evidence for the role of cell stiffness in modulation of volume-regulated anion channels. 
  • Force measurements of the alpha5beta1 integrin-fibronectin interaction. 
  • Imaginary magnetic tweezers for massively parallel surface adhesion spectroscopy. 
  • Is the timing of implantation affected by zona pellucida micromanipulation? 
  • Laser-induced heating in optical traps. 
  • Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines. 
  • Mechanochemistry: Force probes in a bottle. 
  • Microscopes and microinstruments. 
  • Molecular analysis of synchronous and metachronous tumors of the lung: impact on management and prognosis. 
  • Nanomechanical fingerprints of UV damage to DNA. 
  • Pulling geometry-induced errors in single molecule force spectroscopy measurements. 
  • Radiation force imaging of viscoelastic properties with reduced artifacts. 
  • Selective microstimulation of central nervous system neurons. 
  • Signals and noise in micromechanical measurements. 
  • Single molecule mechanical manipulation for studying biological properties of proteins, DNA, and sugars. 
  • Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina. 
  • The motion of a single molecule, the lambda-receptor, in the bacterial outer membrane. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology