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Subject Areas on Research
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(3H)norepinephrine binding: unrelated to catechol-O-methyl transferase.
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A fraction of the ventricular myocardium that has the specificity of the cardiac beta-adrenergic receptor.
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Acetyl-CoA:1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase is directly activated by p38 kinase.
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Activities of the initial enzymes of glycerolipid and sphingolipid synthesis in lung microsomes from rats exposed to air or 85% oxygen.
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Acyl-CoAs are functionally channeled in liver: potential role of acyl-CoA synthetase.
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Adipocyte beta-adrenergic receptors. Identification and subcellular localization by (-)-[3H]dihydroalprenolol binding.
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Affinity chromatography of adrenergic receptors and binding proteins.
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Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro.
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Application of proteomic marker ensembles to subcellular organelle identification.
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Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain.
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Assembly of translocation-competent proteoliposomes from detergent-solubilized rough microsomes.
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Biochemical and cytochemical comparison of surface membranes from normal and dystrophic chickens.
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Biochemical fractionation and assembly of the membrane components that mediate nascent chain targeting and translocation.
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Biosynthesis of renin: multiplicity of active and intermediate forms.
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Calcium accumulation by isolated sarcoplasmic reticulum of skeletal muscle during development in tissue culture.
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Ceramide synthase.
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Cholesterol interaction with the daunorubicin binding site of P-glycoprotein.
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Coal fly ash induces hepatic and pulmonary cytochrome P-450 and sigma-aminolevulinic acid synthetase in rats.
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Debromination of polybrominated diphenyl ether-99 (BDE-99) in carp (Cyprinus carpio) microflora and microsomes.
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Diversity in membrane binding sites of ankyrins. Brain ankyrin, erythrocyte ankyrin, and processed erythrocyte ankyrin associate with distinct sites in kidney microsomes.
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Effects of DDT on eggshell quality and calcium adenosine triphosphatase.
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Effects of inhibition and induction of cytochrome P-450 isozymes on hyperoxic lung injury in rats.
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Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamine metabolism in rats.
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Evidence for two cellular pathways of renin secretion by the mouse submandibular gland.
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Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: implications for interindividual variability in disposition, efficacy, and drug interactions.
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Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart: evidence that the heart has the capacity to synthesize and secrete lipoproteins.
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Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine.
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Human kidney methoxyflurane and sevoflurane metabolism. Intrarenal fluoride production as a possible mechanism of methoxyflurane nephrotoxicity.
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Identification of a novel stage of ribosome/nascent chain association with the endoplasmic reticulum membrane.
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Identification of the cardiac beta-adrenergic receptor protein: solubilization and purification by affinity chromatography.
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In vitro and tissue culture methods for analysis of translation initiation on the endoplasmic reticulum.
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In vitro inhibition of microsomal calcium atpase from eggshell gland of mallard duck.
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In vitro metabolism of cyclosporine A by human kidney CYP3A5.
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In vitro metabolism of the COX-2 inhibitor DFU, including a novel glutathione adduct rearomatization.
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Increased lethality and defective pulmonary clearance of Streptococcus pneumoniae in microsomal prostaglandin E synthase-1-knockout mice.
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Induction of phosphatidylcholine biosynthesis via CDPcholine pathway in lung and liver of rats following intratracheal administration of DDT and endosulfan.
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Isolated beta-adrenergic binding sites: a potential assay vehicle for catecholamines.
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Isolated hormone receptors: physiologic and clinical implications.
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Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation.
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Lung subcellular fractions and surfactant lipid metabolism of rats exposed with DDT or endosulfan intratracheally.
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Membrane topology and biogenesis of eukaryotic signal peptidase.
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Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by human CYP1B1 genetic variants.
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Metabolism of alfentanil by cytochrome p4503a (cyp3a) enzymes.
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Metabolism of methadone and levo-alpha-acetylmethadol (LAAM) by human intestinal cytochrome P450 3A4 (CYP3A4): potential contribution of intestinal metabolism to presystemic clearance and bioactivation.
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Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1.
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Microsomal membranes contain a high affinity binding site for prenylated peptides.
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New lessons in the regulation of glucose metabolism taught by the glucose 6-phosphatase system.
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Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes.
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On the occurrence of cytochrome P-450 and aryl hydrocarbon hydroxylase activity in rat brain.
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Paradoxical Increase in Mortality and Rupture of Intracranial Aneurysms in Microsomal Prostaglandin E2 Synthase Type 1-Deficient Mice: Attenuation by Aspirin.
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Phosphatidylcholine metabolism in lung microsomes and lung surfactant of rats exposed intratracheally to coal fly ash.
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Placental lactogen and growth hormone receptors in human fetal tissues: relationship to fetal plasma human placental lactogen concentrations and fetal growth.
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Prenylated peptides in identification of specific binding proteins.
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Progesterone Metabolites Produced by Cytochrome P450 3A Modulate Uterine Contractility in a Murine Model.
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Prostaglandin E2 in remote control of myocardial remodeling.
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Proteolytic domains of the epidermal growth factor receptor of human placenta.
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Proteomic analysis of mitochondrial-associated ER membranes (MAM) during RNA virus infection reveals dynamic changes in protein and organelle trafficking.
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Reconstitution of secretory protein translocation from detergent-solubilized rough microsomes.
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Release of [3H]norepinephrine from synaptic vesicles isolated from rat brain after the intracisternal administration of [3H]norepinephrine: influence of nucleotides, ions and drugs, and destabilization of transmitter storage caused by acute or chronic lithium administration.
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Ribosome-independent regulation of translocon composition and Sec61alpha conformation.
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Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.
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Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone.
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Specific binding of -adrenergic catecholamines to a subcellular fraction from cardiac muscle.
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Structure and folding of nascent polypeptide chains during protein translocation in the endoplasmic reticulum.
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Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice.
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Subcellular distribution of transmitter-related enzyme activities in discrete areas of the rat dentate gyrus.
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The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment.
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The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background.
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The inhibition of human adrenal steroidogenic enzyme activities by suramin.
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The nature of renin precursor and inactive renin.
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The role of NAD(P)H:quinone oxidoreductase in mitomycin C- and porfiromycin-resistant HCT 116 human colon-cancer cells.
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The signal sequence receptor, unlike the signal recognition particle receptor, is not essential for protein translocation.
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The synthesis and secretion of gamma-globulin by lymph node cells. V. The dissociation of the microsome-antibody complex with enzymatically and chemically altered gamma-globulins.
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Upregulation of cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) in wall of ruptured human cerebral aneurysms: preliminary results.
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