Mitochondria

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  Subject Areas on Research

  • 6-Hydroxydopamine injections into the nigrostriatal pathway attenuate striatal malonate and 3-nitropropionic acid lesions. 
  • In Vivo Effects of Silver Nanoparticles on Development, Behavior, and Mitochondrial Function are Altered by Genetic Defects in Mitochondrial Dynamics. 
  • A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation. 
  • A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect. 
  • A GH3-like domain in reaper is required for mitochondrial localization and induction of IAP degradation. 
  • A bioenergetics assay for studying the effects of environmental stressors on mitochondrial function in vivo in zebrafish larvae. 
  • A chemical glycoproteomics platform reveals O-GlcNAcylation of mitochondrial voltage-dependent anion channel 2. 
  • A genetic polymorphism that is associated with mitochondrial energy metabolism increases risk of fibromyalgia. 
  • A guide to interrogating immunometabolism. 
  • A high mitochondrial transport rate characterizes CNS neurons with high axonal regeneration capacity. 
  • A link between endoplasmic reticulum stress-induced β-cell apoptosis and the group VIA Ca2+-independent phospholipase A2 (iPLA2β). 
  • A mathematical model for persistent post-CSD vasoconstriction. 
  • A model for fast axonal transport. 
  • A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice. 
  • A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury. 
  • A new era for electron bifurcation. 
  • A new face on apoptosis: death-associated protein 3 and PDCD9 are mitochondrial ribosomal proteins. 
  • A new role for ATM: regulating mitochondrial function and mitophagy. 
  • A novel interface for variable flow nanoscale LC/MS/MS for improved proteome coverage. 
  • A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. 
  • A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif. 
  • A novel redox regulator, MnTnBuOE-2-PyP5+, enhances normal hematopoietic stem/progenitor cell function. 
  • A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO. 
  • A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins. 
  • A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability. 
  • A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation. 
  • ABCs of erythroid mitochondrial iron uptake. 
  • AIF Is "Always In Fashion" for T Cells. 
  • ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase. 
  • ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy. 
  • AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival. 
  • Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signaling. 
  • Abnormal fatty acid metabolism in spinal muscular atrophy may predispose to perioperative risks. 
  • Acclimation of C2C12 myoblasts to physiological glucose concentrations for in vitro diabetes research. 
  • Acetaminophen toxicity in cultured trout liver cells. I. Morphological alterations and effects on cytochrome P450 1A1. 
  • Acetate Metabolism in Physiology, Cancer, and Beyond. 
  • Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals. 
  • Acetate metabolism and aging: An emerging connection. 
  • Acetylation of mitochondrial proteins. 
  • Acquisition of mitochondrial dysregulation and resistance to mitochondrial-mediated apoptosis after genotoxic insult in normal human fibroblasts: a possible model for early stage carcinogenesis. 
  • Actions of steroids in mitochondria. 
  • Activation of mitochondrial biogenesis by heme oxygenase-1-mediated NF-E2-related factor-2 induction rescues mice from lethal Staphylococcus aureus sepsis. 
  • Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation. 
  • Acute Exposure to Permethrin Modulates Behavioral Functions, Redox, and Bioenergetics Parameters and Induces DNA Damage and Cell Death in Larval Zebrafish. 
  • Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis. 
  • Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice. 
  • Acyl-CoAs are functionally channeled in liver: potential role of acyl-CoA synthetase. 
  • Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-Mediated Inhibition of Mitochondrial Respiration. 
  • Adaptation of skeletal muscle to increased contractile activity. Expression nuclear genes encoding mitochondrial proteins. 
  • Adipocyte beta-adrenergic receptors. Identification and subcellular localization by (-)-[3H]dihydroalprenolol binding. 
  • Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance. 
  • Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration. 
  • Age-related metabolic fatigue during low glucose conditions in rat hippocampus. 
  • Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology. 
  • Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells. 
  • Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture. 
  • Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson's disease. 
  • Altered Mitochondrial Homeostasis during Systemic Lupus Erythematosus Impairs Neutrophil Extracellular Trap Formation Rendering Neutrophils Ineffective at Combating Staphylococcus aureus. 
  • Altered distribution of mitochondria and actin fibers in 3T3 cells cultured on microcarriers. 
  • Altered mitochondrial redox responses in gram negative septic shock in primates. 
  • Amyloid precursor protein and amyloid beta-peptide bind to ATP synthase and regulate its activity at the surface of neural cells. 
  • An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation. 
  • Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal. 
  • Analysis of European mitochondrial haplogroups with Alzheimer disease risk. 
  • Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch. 
  • Anti-CD40 ligand monoclonal antibody delays the progression of murine autoimmune cholangitis. 
  • Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas. 
  • Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes. 
  • Apoptosis and B cell tolerance. 
  • Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c. 
  • Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function. 
  • Astaxanthin but not quercetin preserves mitochondrial integrity and function, ameliorates oxidative stress, and reduces heat-induced skeletal muscle injury. 
  • Autophagy is essential for mitochondrial clearance in mature T lymphocytes. 
  • Autophagy protects against aminochrome-induced cell death in substantia nigra-derived cell line. 
  • Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1. 
  • Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes. 
  • Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide. 
  • BCAA catabolism in brown fat controls energy homeostasis through SLC25A44. 
  • BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo. 
  • Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. 
  • Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release. 
  • Bi-allelic KARS1 pathogenic variants affecting functions of cytosolic and mitochondrial isoforms are associated with a progressive and multisystem disease. 
  • Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder. 
  • Biochemical Underpinnings of Immune Cell Metabolic Phenotypes. 
  • Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation. 
  • Blunted fat oxidation upon submaximal exercise is partially compensated by enhanced glucose metabolism in children, adolescents, and young adults with Barth syndrome. 
  • Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart. 
  • CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC. 
  • CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice. 
  • CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation. 
  • CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis. 
  • CFLAR/c-FLIPL: a star in the autophagy, apoptosis and necroptosis alliance. 
  • CODAS syndrome is associated with mutations of LONP1, encoding mitochondrial AAA+ Lon protease. 
  • Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-Induced Myeloid-Derived Suppressor Cells. 
  • Canalicular reticulum in vestibular hair cells. 
  • Cancer-associated isocitrate dehydrogenase 1 (IDH1) R132H mutation and d-2-hydroxyglutarate stimulate glutamine metabolism under hypoxia. 
  • Carbon monoxide, oxidative stress, and mitochondrial permeability pore transition. 
  • Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling. 
  • Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart. 
  • Caspase-8 levels affect necessity for mitochondrial amplification in death ligand-induced glioma cell apoptosis. 
  • Catch me if you can: the link between autophagy and viruses. 
  • Cellular energetics and mitochondrial uncoupling in canine aging. 
  • Ceramide synthase. 
  • Cerebral cortical microfluorometry at isosbestic wavelengths for correction of vascular artifact. 
  • Cerebral mitochondrial metabolism in early Parkinson's disease. 
  • Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging. 
  • Chemical Adducts of Reactive Flavor Aldehydes Formed in E-Cigarette Liquids Are Cytotoxic and Inhibit Mitochondrial Function in Respiratory Epithelial Cells. 
  • Chronic Ethanol Metabolism Inhibits Hepatic Mitochondrial Superoxide Dismutase via Lysine Acetylation. 
  • Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8+ T cells and impede CAR T-cell efficacy. 
  • Circulating mitochondria in deceased organ donors are associated with immune activation and early allograft dysfunction. 
  • Clinical and Molecular Characteristics of Mitochondrial Dysfunction in Autism Spectrum Disorder. 
  • Clorgyline and deprenyl attenuate striatal malonate and 3-nitropropionic acid lesions. 
  • Co-regulation of nuclear respiratory factor-1 by NFkappaB and CREB links LPS-induced inflammation to mitochondrial biogenesis. 
  • Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity. 
  • Cofractionation of the 17-kD PK 14105 binding site protein with solubilized peripheral-type benzodiazepine binding sites. 
  • Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer. 
  • Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial-lysosomal axis and alleviates autophagic blockage in Pompe disease. 
  • Coming of age: molecular drivers of aging and therapeutic opportunities. 
  • Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae. 
  • Comparative population structure of two deep-sea hydrothermal-vent-associated decapods (Chorocaris sp. 2 and Munidopsis lauensis) from southwestern Pacific back-arc basins. 
  • Comparative toxicity of C60 aggregates toward mammalian cells: role of tetrahydrofuran (THF) decomposition. 
  • Comparison of proteomic and metabolomic profiles of mutants of the mitochondrial respiratory chain in Caenorhabditis elegans. 
  • Compartmentalized nitrosation and nitration in mitochondria. 
  • Compartmentation of Metabolism of the C12-, C9-, and C5-n-dicarboxylates in Rat Liver, Investigated by Mass Isotopomer Analysis: ANAPLEROSIS FROM DODECANEDIOATE. 
  • Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact. 
  • Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+. 
  • Control of innate immune signaling and membrane targeting by the Hepatitis C virus NS3/4A protease are governed by the NS3 helix α0. 
  • Convergence of Parkin, PINK1, and α-Synuclein on Stress-induced Mitochondrial Morphological Remodeling. 
  • Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells. 
  • Cryptococcus neoformans mitochondrial superoxide dismutase: an essential link between antioxidant function and high-temperature growth. 
  • Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype. 
  • Curcumin Ameliorates Heat-Induced Injury through NADPH Oxidase-Dependent Redox Signaling and Mitochondrial Preservation in C2C12 Myoblasts and Mouse Skeletal Muscle. 
  • Cyclophilin active site mutants have native prolyl isomerase activity with a protein substrate. 
  • Cyclosporin A inhibits chromium(VI)-induced apoptosis and mitochondrial cytochrome c release and restores clonogenic survival in CHO cells. 
  • Cytochrome c peroxidase contributes to the antioxidant defense of Cryptococcus neoformans. 
  • Cytosolic hydroxymethyldihydropterin pyrophosphokinase/dihydropteroate synthase from Arabidopsis thaliana: a specific role in early development and stress response. 
  • Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. 
  • Decreased Uptake and Enhanced Mitochondrial Protection Underlie Reduced Toxicity of Nanoceria in Human Monocyte-Derived Macrophages. 
  • Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability. 
  • Deficiency in SLC25A1, encoding the mitochondrial citrate carrier, causes combined D-2- and L-2-hydroxyglutaric aciduria. 
  • Degradation of engulfed mitochondria is rate-limiting in Optineurin-mediated mitophagy in neurons. 
  • Delineation of the signaling pathways involved in glucocorticoid-induced and spontaneous apoptosis of rat thymocytes. 
  • Detection of cytochrome C in a single cell using an optical nanobiosensor. 
  • Development of Saccharomyces cerevisiae as a model pathogen. A system for the genetic identification of gene products required for survival in the mammalian host environment. 
  • Development of type II pneumocytes in rat lung. 
  • Diazepam promotes ATP recovery and prevents cytochrome c release in hippocampal slices after in vitro ischemia. 
  • Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms. 
  • Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling. 
  • Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins. 
  • Difference between mitochondrial RNase P and nuclear RNase P. 
  • Differences in O2 availability resolve the apparent discrepancies in metabolic intrinsic optical signals in vivo and in vitro. 
  • Differences in Reperfusion-Induced Mitochondrial Oxidative Stress and Cell Death Between Hippocampal CA1 and CA3 Subfields Are Due to the Mitochondrial Thioredoxin System. 
  • Differential localization and potency of manganese porphyrin superoxide dismutase-mimicking compounds in Saccharomyces cerevisiae. 
  • Differential metabolic and electrical activity in the somatic sensory cortex of juvenile and adult rats. 
  • Discovering pathways of sarcopenia in older adults: a role for insulin resistance on mitochondria dysfunction. 
  • Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy. 
  • Disruption of skeletal muscle mitochondrial network genes and miRNAs in amyotrophic lateral sclerosis. 
  • Distinct effects of tafazzin deletion in differentiated and undifferentiated mitochondria. 
  • Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion. 
  • Diverse functions within the IAP family. 
  • Does dopamine contribute to striatal damage caused by impaired mitochondrial function? 
  • Dopamine Metabolism May Have Unexpected Benefits for Mitochondrial Energy Production. 
  • Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction. 
  • Drosophila topo IIIalpha is required for the maintenance of mitochondrial genome and male germ-line stem cells. 
  • Dynamin and FtsZ. Missing links in mitochondrial and bacterial division. 
  • Dysfunctional T cell metabolism in the tumor microenvironment. 
  • Dysregulated metabolism contributes to oncogenesis. 
  • Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors. 
  • Dystonia with and without deafness is caused by TIMM8A mutation. 
  • EGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activity. 
  • EGFR and EGFRvIII undergo stress- and EGFR kinase inhibitor-induced mitochondrial translocalization: a potential mechanism of EGFR-driven antagonism of apoptosis. 
  • ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease. 
  • ER stress modulates cellular metabolism. 
  • ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer. 
  • ERα Signaling Increased IL-17A Production in Th17 Cells by Upregulating IL-23R Expression, Mitochondrial Respiration, and Proliferation. 
  • Early development of near-infrared spectroscopy at Duke University. 
  • Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity. 
  • Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines. 
  • Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans. 
  • Ecological significance of mitochondrial toxicants. 
  • Editorial overview: Biological pathways for electrons, protons and photo-excitations. 
  • Effect of intratracheally administered DDT and endosulfan on pulmonary and hepatic respiratory cytochromes. 
  • Effect of molecular characteristics on cellular uptake, subcellular localization, and phototoxicity of Zn(II) N-alkylpyridylporphyrins. 
  • Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. 
  • Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans. 
  • Effects of Immunosuppressive Medications on Mitochondrial Function. 
  • Effects of air pollution on mitochondrial function, mitochondrial DNA methylation, and mitochondrial peptide expression. 
  • Effects of buthionine sulfoximine and diethyl maleate on glutathione turnover in the channel catfish. 
  • Effects of inhibition of mitochondrial protein synthesis in skeletal muscle. 
  • Effects of methyl and inorganic mercury exposure on genome homeostasis and mitochondrial function in Caenorhabditis elegans. 
  • Effects of volatile anesthetics on N-methyl-D-aspartate excitotoxicity in primary rat neuronal-glial cultures. 
  • Electron microscopy of young Candida albicans chlamydospores. 
  • Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States. 
  • Emerging mechanistic targets in lung injury induced by combustion-generated particles. 
  • Endurance exercise attenuates juvenile irradiation-induced skeletal muscle functional decline and mitochondrial stress. 
  • Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism. 
  • Enhanced sensitivity to cytochrome c-induced apoptosis mediated by PHAPI in breast cancer cells. 
  • Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase. 
  • Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation. 
  • Evidence for Compartmentalized Axonal Mitochondrial Biogenesis: Mitochondrial DNA Replication Increases in Distal Axons As an Early Response to Parkinson's Disease-Relevant Stress. 
  • Evidence of severe mitochondrial oxidative stress and a protective effect of low oxygen in mouse models of inherited photoreceptor degeneration. 
  • Exploiting the complementary nature of LC/MALDI/MS/MS and LC/ESI/MS/MS for increased proteome coverage. 
  • Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans. 
  • Expression of a mitochondrial progesterone receptor in human spermatozoa correlates with a progestin-dependent increase in mitochondrial membrane potential. 
  • Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant. 
  • Expression of mitofusin 2(R94Q) in a transgenic mouse leads to Charcot-Marie-Tooth neuropathy type 2A. 
  • Extensive uptake of α-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage. 
  • Failure to induce apoptosis via BCL-2 family proteins underlies lack of efficacy of combined MEK and PI3K inhibitors for KRAS-mutant lung cancers. 
  • Ferrochelatase is a conserved downstream target of the blue light-sensing White collar complex in fungi. 
  • Fibrotic Changes to Schlemm's Canal Endothelial Cells in Glaucoma. 
  • Filling a GAP(DH) in caspase-independent cell death. 
  • First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway. 
  • Fish oil slows prostate cancer xenograft growth relative to other dietary fats and is associated with decreased mitochondrial and insulin pathway gene expression. 
  • Fluorescent probes that stain living nerve terminals. 
  • Fluorescent pulse-chase labeling to monitor long-term mitochondrial degradation in primary hippocampal neurons. 
  • From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans. 
  • Fruit flies, bile acids, and Parkinson disease: a mitochondrial connection? 
  • Functional characterization of a mitochondrial Ser/Thr protein phosphatase in cell death regulation. 
  • Functional diversity of mammalian type 2C protein phosphatase isoforms: new tales from an old family. 
  • Functions of FKBP12 and mitochondrial cyclophilin active site residues in vitro and in vivo in Saccharomyces cerevisiae. 
  • Functions of cytochrome c in regulation of electron transfer and protein folding. 
  • GOBASE--a database of organelle and bacterial genome information. 
  • GW112, a novel antiapoptotic protein that promotes tumor growth. 
  • Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789. 
  • Genomic characterization of POS5, the Saccharomyces cerevisiae mitochondrial NADH kinase. 
  • Global transcriptome profile of Cryptococcus neoformans during exposure to hydrogen peroxide induced oxidative stress. 
  • Glutamate decreases mitochondrial size and movement in primary forebrain neurons. 
  • Glutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagy. 
  • Glutamate mobilizes [Zn2+] through Ca2+ -dependent reactive oxygen species accumulation. 
  • Glutamine transport into isolated renal membrane vesicles from normal and acidotic rats. 
  • Growth factor erv1-like modulates Drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells. 
  • Growth factors can influence cell growth and survival through effects on glucose metabolism. 
  • HASF is a stem cell paracrine factor that activates PKC epsilon mediated cytoprotection. 
  • HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation. 
  • HIF-1 Alpha Regulates the Response of Primary Sarcomas to Radiation Therapy through a Cell Autonomous Mechanism. 
  • Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts. 
  • Hedgehog Signaling Regulates Metabolism and Polarization of Mammary Tumor-Associated Macrophages. 
  • Hedgehog controls hepatic stellate cell fate by regulating metabolism. 
  • Heme Oxygenase-1/Carbon Monoxide System and Embryonic Stem Cell Differentiation and Maturation into Cardiomyocytes. 
  • Heme proteins and nitric oxide (NO): the neglected, eloquent chemistry in NO redox signaling and regulation. 
  • Hepatic mitochondrial dysfunction is a feature of Glycogen Storage Disease Type Ia (GSDIa). 
  • Heterogeneity in mitochondrial morphology and membrane potential is independent of the nuclear division cycle in multinucleate fungal cells. 
  • Heterogeneity of calcium compartmentation: electron probe analysis of renal tubules. 
  • Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin. 
  • High-fat diet-induced colonocyte dysfunction escalates microbiota-derived trimethylamine N-oxide. 
  • High-performance liquid chromatography separations coupled with coulometric electrode array detectors: a unique approach to metabolomics. 
  • Homeostatic control of lymphocyte survival: potential origins and implications. 
  • Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. 
  • Human mitochondrial DNA polymerase gamma exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers 
  • Human platelets exhibit chemotaxis using functional N-formyl peptide receptors. 
  • Human pluripotent stem cells decouple respiration from energy production. 
  • Hydroxyl radical production in the brain after CO hypoxia in rats. 
  • IFI16-STING-NF-κB signaling controls exogenous mitochondrion-induced endothelial activation. 
  • IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity. 
  • IRGM1 links mitochondrial quality control to autoimmunity. 
  • Identification of a protective proteomic signature and a potential therapeutic target in diabetic nephropathy. 
  • Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique. 
  • Identification of four proteins from the small subunit of the mammalian mitochondrial ribosome using a proteomics approach. 
  • Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis. 
  • Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death. 
  • Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2. 
  • Implementing a cumulative supermatrix approach for a comprehensive phylogenetic study of the Teloschistales (Pezizomycotina, Ascomycota). 
  • Implication of mitochondrial involvement in apoptotic activity of fragile histidine triad gene: application of synchronous luminescence spectroscopy. 
  • In Vivo Determination of Mitochondrial Function Using Luciferase-Expressing Caenorhabditis elegans: Contribution of Oxidative Phosphorylation, Glycolysis, and Fatty Acid Oxidation to Toxicant-Induced Dysfunction. 
  • In situ cryofixation of kidney for electron probe X-ray microanalysis. 
  • In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. 
  • In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease. 
  • In vivo modulation of norepinephrine-induced cerebral oxygenation states by hypoxia and hyperoxia. 
  • Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation. 
  • Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy. 
  • Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity. 
  • Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies. 
  • Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer. 
  • Inhibition of Sphingosine Kinase 2 Results in PARK2-Mediated Mitophagy and Induces Apoptosis in Multiple Myeloma. 
  • Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper. 
  • Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK. 
  • Interference of nuclear mitochondrial DNA segments in mitochondrial DNA testing resembles biparental transmission of mitochondrial DNA in humans. 
  • Intraspecific variation in symbiont genomes: bottlenecks and the aphid-buchnera association. 
  • Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. 
  • Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells. 
  • Isolation of -L-glutaminyl 4-hydroxybenzene and -L-glutaminyl 3,4-benzoquinone: a natural sulfhydryl reagent, from sporulating gill tissue of the mushroom Agaricus bisporus. 
  • Isolation of the nuclear gene encoding a subunit of the yeast mitochondrial RNA polymerase. 
  • Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism. 
  • Keto acid metabolites of branched-chain amino acids inhibit oxidative stress-induced necrosis and attenuate myocardial ischemia-reperfusion injury. 
  • Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2. 
  • Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis. 
  • LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease. 
  • LOCAL TRANSLATION. Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling". 
  • LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson's disease. 
  • Leptin metabolically licenses T cells for activation to link nutrition and immunity. 
  • Light scattering measurements of subcellular structure provide noninvasive early detection of chemotherapy-induced apoptosis. 
  • Linking Mitochondrial Dysfunction to Organismal and Population Health in the Context of Environmental Pollutants: Progress and Considerations for Mitochondrial Adverse Outcome Pathways. 
  • Lipid-induced metabolic dysfunction in skeletal muscle. 
  • Lipid-induced mitochondrial stress and insulin action in muscle. 
  • Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1. 
  • Localized glucose import, glycolytic processing, and mitochondria generate a focused ATP burst to power basement-membrane invasion. 
  • Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells. 
  • Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis. 
  • Lysosomal degradation of depolarized mitochondria is rate-limiting in OPTN-dependent neuronal mitophagy. 
  • MAVS Coordination of Antiviral Innate Immunity. 
  • MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver. 
  • MFN1 deacetylation activates adaptive mitochondrial fusion and protects metabolically challenged mitochondria. 
  • MIBG inhibits respiration: potential for radio- and hyperthermic sensitization. 
  • MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation. 
  • Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells. 
  • Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite. 
  • Manganese porphyrin reduces renal injury and mitochondrial damage during ischemia/reperfusion. 
  • Manganese superoxide dismutase, MnSOD and its mimics. 
  • Manganese superoxide dismutases from Escherichia coli and from yeast mitochondria: preliminary x-ray crystallographic studies. 
  • Mapping Activity-Dependent Quasi-stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging. 
  • Maternally inherited peptides as strain-specific chemosignals. 
  • Mcl-1 rescues a glitch in the matrix. 
  • Measurement of 25-hydroxyvitamin D 1-alpha-hydroxylase activity in mammalian kidney. 
  • Measurement of Reactive Oxygen Species by Fluorescent Probes in Pancreatic Cancer Cells. 
  • Mechanism of apoptosis and determination of cellular fate in chromium(VI)-exposed populations of telomerase-immortalized human fibroblasts. 
  • Mechanisms of MAVS regulation at the mitochondrial membrane. 
  • Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction. 
  • Metabolic Teamwork in the Stem Cell Niche. 
  • Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. 
  • Metabolic capacity regulates iron homeostasis in endothelial cells. 
  • Metabolic coupling factors in pancreatic beta-cell signal transduction. 
  • Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever. 
  • Metabolic inflexibility: when mitochondrial indecision leads to metabolic gridlock. 
  • Metabolic inhibition-induced transient Ca2+ increase depends on mitochondria in a human proximal renal cell line. 
  • Metabolic landscape of the tumor microenvironment at single cell resolution. 
  • Metabolic regulation of Akt: roles reversed. 
  • Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. 
  • Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. 
  • Metabolic stress is a barrier to Epstein-Barr virus-mediated B-cell immortalization. 
  • Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester model of cystinosis. 
  • Metabolism and vascular fatty acid transport. 
  • Metabolomic analysis shows differential hepatic effects of T2 and T3 in rats after short-term feeding with high fat diet. 
  • Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. 
  • Metabolomics applied to diabetes research: moving from information to knowledge. 
  • Metabolomics in the study of aging and caloric restriction. 
  • Metformin Targets Central Carbon Metabolism and Reveals Mitochondrial Requirements in Human Cancers. 
  • Methamphetamine toxicity is attenuated in mice that overexpress human manganese superoxide dismutase. 
  • Method for the structural analysis of Twinkle mitochondrial DNA helicase by cryo-EM. 
  • Methods to Visualize MAVS Subcellular Localization. 
  • MicroRNA-23a Curbs Necrosis during Early T Cell Activation by Enforcing Intracellular Reactive Oxygen Species Equilibrium. 
  • Microparticles in the blood of patients with SLE: Size, content of mitochondria and role in circulating immune complexes. 
  • Mitochondria and nitric oxide. 
  • Mitochondria as a target of environmental toxicants 
  • Mitochondria as a target of organophosphate and carbamate pesticides: Revisiting common mechanisms of action with new approach methodologies. 
  • Mitochondria at the crossroad of apoptotic cell death. 
  • Mitochondria in Ovarian Aging and Reproductive Longevity. 
  • Mitochondria in apoptosis and human disease. 
  • Mitochondria in lung biology and pathology: more than just a powerhouse. 
  • Mitochondria in sporadic amyotrophic lateral sclerosis. 
  • Mitochondria, Oxytocin, and Vasopressin: Unfolding the Inflammatory Protein Response. 
  • Mitochondria, cell death, and B cell tolerance. 
  • Mitochondria, energetics, epigenetics, and cellular responses to stress. 
  • Mitochondria-enriched protrusions are associated with brain and intestinal stem cells in Drosophila. 
  • Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy. 
  • Mitochondrial DNA Mutagenesis: Feature of and Biomarker for Environmental Exposures and Aging. 
  • Mitochondrial DNA damage as a potential biomarker of LRRK2 kinase activity in LRRK2 Parkinson's disease. 
  • Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans. 
  • Mitochondrial DNA, oxidants, and innate immunity. 
  • Mitochondrial DNA-depleted A549 cells are resistant to bleomycin. 
  • Mitochondrial Dysfunction in Critical Illness: Implications for Nutritional Therapy. 
  • Mitochondrial Dysfunction in Lung Pathogenesis. 
  • Mitochondrial Dysfunction: Metabolic Drivers of Pulmonary Hypertension. 
  • Mitochondrial FtsZ in a chromophyte alga 
  • Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome. 
  • Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes. 
  • Mitochondrial NADH as the bellwether of tissue O2 delivery. 
  • Mitochondrial Oxidative Phosphorylation Complex Regulates NLRP3 Inflammasome Activation and Predicts Patient Survival in Nasopharyngeal Carcinoma. 
  • Mitochondrial Quality Control as a Therapeutic Target. 
  • Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy. 
  • Mitochondrial ROS and NLRP3 inflammasome in acute ozone-induced murine model of airway inflammation and bronchial hyperresponsiveness. 
  • Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning. 
  • Mitochondrial Toxicity. 
  • Mitochondrial and intrinsic optical signals imaged during hypoxia and spreading depression in rat hippocampal slices. 
  • Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice. 
  • Mitochondrial bioenergetic changes during development as an indicator of C. elegans health-span. 
  • Mitochondrial biogenesis in the pulmonary vasculature during inhalational lung injury and fibrosis. 
  • Mitochondrial biogenesis restores oxidative metabolism during Staphylococcus aureus sepsis. 
  • Mitochondrial biogenesis: regulation by endogenous gases during inflammation and organ stress. 
  • Mitochondrial dynamics and Parkinson's disease: focus on parkin. 
  • Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans 
  • Mitochondrial dysfunction in ataxia-telangiectasia. 
  • Mitochondrial fusion is regulated by Reaper to modulate Drosophila programmed cell death. 
  • Mitochondrial fusion, fission, and mitochondrial toxicity. 
  • Mitochondrial gene expression in mammalian striated muscle. Evidence that variation in gene dosage is the major regulatory event. 
  • Mitochondrial generation of reactive oxygen species after brain ischemia in the rat. 
  • Mitochondrial genetic background in Ghanaian patients with primary open-angle glaucoma. 
  • Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs. 
  • Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage. 
  • Mitochondrial localization of Reaper to promote inhibitors of apoptosis protein degradation conferred by GH3 domain-lipid interactions. 
  • Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis. 
  • Mitochondrial metabolism is a key regulator of the fibro-inflammatory and adipogenic stromal subpopulations in white adipose tissue. 
  • Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues. 
  • Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis. 
  • Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. 
  • Mitochondrial oxidant production by a pollutant dust and NO-mediated apoptosis in human alveolar macrophage. 
  • Mitochondrial oxidative stress after carbon monoxide hypoxia in the rat brain. 
  • Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. 
  • Mitochondrial polymorphism A10398G and Haplogroup I are associated with Fuchs' endothelial corneal dystrophy. 
  • Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. 
  • Mitochondrial protein acetylation regulates metabolism. 
  • Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver. 
  • Mitochondrial quality control in alveolar epithelial cells damaged by S. aureus pneumonia in mice. 
  • Mitochondrial quality-control dysregulation in conditional HO-1-/- mice. 
  • Mitochondrial response and resilience to anthropogenic chemicals during embryonic development. 
  • Mitochondrial sirtuins. 
  • Mitochondrial uncoupling: role of uncoupling protein anion carriers and relationship to thermogenesis and weight control "the benefits of losing control". 
  • Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus. 
  • Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise. 
  • Mitophagy in the little lymphocytes: an essential role for autophagy in mitochondrial clearance in T lymphocytes. 
  • Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor. 
  • Motor deficits are triggered by reperfusion-reoxygenation injury as diagnosed by MRI and by a mechanism involving oxidants. 
  • Multiple metabolic changes mediate the response of Caenorhabditis elegans to the complex I inhibitor rotenone. 
  • Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility. 
  • Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A. 
  • Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. 
  • NASH and cryptogenic cirrhosis: a histological analysis. 
  • NMR studies of an immunomodulatory benzodiazepine binding to its molecular target on the mitochondrial F(1)F(0)-ATPase. 
  • Nano-C60 cytotoxicity is due to lipid peroxidation. 
  • Near-infrared monitoring of cerebral oxygen sufficiency. I. Spectra of cytochrome c oxidase. 
  • Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in C. elegans. 
  • Neuronal CRTC-1 governs systemic mitochondrial metabolism and lifespan via a catecholamine signal. 
  • Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy. 
  • Neuroprotection from delayed postischemic administration of a metalloporphyrin catalytic antioxidant. 
  • Neuroprotective effects of creatine administration against NMDA and malonate toxicity. 
  • Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation. 
  • New insights into oxidative stress and inflammation during diabetes mellitus-accelerated atherosclerosis. 
  • New insights into protein S-nitrosylation. Mitochondria as a model system. 
  • Nicotinamide pre-treatment ameliorates NAD(H) hyperoxidation and improves neuronal function after severe hypoxia. 
  • Nitric oxide donors protect murine myocardium against infarction via modulation of mitochondrial permeability transition. 
  • Nitric oxide inhibits expression of cytochrome B in endotoxin-stimulated murine macrophages. 
  • Nitric oxide production and regulation of neuronal NOS in tyrosine hydroxylase containing neurons. 
  • Noncanonical secondary structure stabilizes mitochondrial tRNA(Ser(UCN)) by reducing the entropic cost of tertiary folding. 
  • Nonselective autophagy reduces mitochondrial content during starvation in Caenorhabditis elegans. 
  • Normal platelet mitochondrial complex I activity in Huntington's disease. 
  • Novel ceramide analogs as potential chemotherapeutic agents in breast cancer. 
  • Novel mitochondrial derived Nuclear Excisosome degrades nuclei during differentiation of prosimian Galago (bush baby) monkey lenses. 
  • Obesity-related derangements in metabolic regulation. 
  • Observations on cell volume, ultrastructure, mitochondrial conformation and vital-dye uptake in Ehrlich ascites tumor cells. Effects of inhibiting energy production and function of the plasma membrane. 
  • Optical and pharmacological tools to investigate the role of mitochondria during oxidative stress and neurodegeneration. 
  • Oral tolerance and pyruvate dehydrogenase in patients with primary biliary cirrhosis. 
  • Osteopontin deficiency ameliorates Alport pathology by preventing tubular metabolic deficits. 
  • Osteopontin inhibits expression of cytochrome c oxidase in RAW 264.7 murine macrophages. 
  • Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity. 
  • Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytes. 
  • Oxidant-induced cell death in retinal pigment epithelium cells mediated through the release of apoptosis-inducing factor. 
  • Oxidations in kidney mitochondria of heat-exposed rats: regulation by cytochrome c. 
  • Oxidative activities in mitochondria-like particles from Setaria digitata, a filarial parasite. 
  • Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential. 
  • Oxygen flux analysis to understand the biological function of sirtuins. 
  • Oxygen-induced mitochondrial biogenesis in the rat hippocampus. 
  • PCR-Based Determination of Mitochondrial DNA Copy Number in Multiple Species. 
  • PD-linked CHCHD2 mutations impair CHCHD10 and MICOS complex leading to mitochondria dysfunction. 
  • PGC-1alpha mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle. 
  • PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart. 
  • PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans. 
  • Panretinal photocoagulation and retinal oxygenation in normal and diabetic cats. 
  • Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli. 
  • Pathways of apoptosis in lymphocyte development, homeostasis, and disease. 
  • Patients with autoimmune hepatitis who have antimitochondrial antibodies need long-term follow-up to detect late development of primary biliary cirrhosis. 
  • Peripheral Blood Mononuclear Cells Demonstrate Mitochondrial Damage Clearance During Sepsis. 
  • Peroxisome proliferator-activated receptor-alpha regulates fatty acid utilization in primary human skeletal muscle cells. 
  • Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production. 
  • Persistent systemic inflammation in chronic critical illness. 
  • Pharmacological targeting of the mitochondrial phosphatase PTPMT1. 
  • Phenotypic abnormalities in macrophages from leptin-deficient, obese mice. 
  • Phorbol myristate acetate stimulates microtubule and 10-nm filament extension and lysosome redistribution in mouse macrophages. 
  • Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria. 
  • Phylogenetic analyses of morphological evolution in the gametophyte and sporophyte generations of the moss order Hookeriales (Bryopsida). 
  • Phylogeography of a Morphologically Cryptic Golden Mole Assemblage from South-Eastern Africa. 
  • Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men. 
  • Platelet mitochondrial complex I and I+III activities do not correlate with cerebral mitochondrial oxidative metabolism. 
  • Pleiotropic Mitochondria: The Influence of Mitochondria on Neuronal Development and Disease. 
  • Pollutant particles enhanced H2O2 production from NAD(P)H oxidase and mitochondria in human pulmonary artery endothelial cells. 
  • Polycyclic aromatic hydrocarbon and hypoxia exposures result in mitochondrial dysfunction in zebrafish. 
  • Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria. 
  • Population genetics of a polyploid: is there hybridization between lineages of Hyla versicolor? 
  • Post-cytochrome C protection from apoptosis conferred by a MAPK pathway in Xenopus egg extracts. 
  • Postnatal development and plasticity of specialized muscle fiber characteristics in the hindlimb. 
  • Pro-thrombotic and pro-oxidant effects of diet-induced hyperhomocysteinemia. 
  • Progesterone Increases Mitochondria Membrane Potential in Non-human Primate Oocytes and Embryos. 
  • Progesterone stimulates mitochondrial activity with subsequent inhibition of apoptosis in MCF-10A benign breast epithelial cells. 
  • Progressive mitochondrial protein lysine acetylation and heart failure in a model of Friedreich's ataxia cardiomyopathy. 
  • Protecting the permeability pore and mitochondrial biogenesis. 
  • Protective role of transient pore openings in calcium handling by cardiac mitochondria. 
  • Proteomic analysis of mitochondrial-associated ER membranes (MAM) during RNA virus infection reveals dynamic changes in protein and organelle trafficking. 
  • Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation. 
  • Purification and characterization of a protein associated with peripheral-type benzodiazepine binding sites. 
  • Purifying selection, sequence composition, and context-specific indel mutations shape intraspecific variation in a bacterial endosymbiont. 
  • Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration. 
  • Quantifying Competition among Mitochondrial Protein Acylation Events Induced by Ethanol Metabolism. 
  • Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. 
  • Quantitative microchemical imaging of calcium in Na-K pump inhibited heart cells. 
  • R73A and H144Q mutants of the yeast mitochondrial cyclophilin Cpr3 exhibit a low prolyl isomerase activity in both peptide and protein-folding assays. 
  • Racial differences in circulating mitochondria-derived peptides may contribute to prostate cancer health disparities. 
  • Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium. 
  • Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2. 
  • Real-time quantitative elemental analysis and mapping: microchemical imaging in cell physiology. 
  • Reaper-induced apoptosis in a vertebrate system. 
  • Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity. 
  • Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis. 
  • Reduced mitochondrial activity in colonocytes facilitates AMPKα2-dependent inflammation. 
  • Reducing mitochondrial reads in ATAC-seq using CRISPR/Cas9. 
  • Reduction of manganese porphyrins by flavoenzymes and submitochondrial particles: a catalytic cycle for the reduction of peroxynitrite. 
  • Regulation of T-cell survival and mitochondrial homeostasis by TSC1. 
  • Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation. 
  • Regulation of cytochrome c oxidase subunit 1 (COX1) expression in Cryptococcus neoformans by temperature and host environment. 
  • Regulation of mitochondrial biogenesis and its intersection with inflammatory responses. 
  • Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability. 
  • Regulation of mitochondrial processes by protein S-nitrosylation. 
  • Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL. 
  • Reproductive Functions of the Mitochondrial Progesterone Receptor (PR-M). 
  • Resistance of mitochondrial DNA to cadmium and Aflatoxin B1 damage-induced germline mutation accumulation in C. elegans. 
  • Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels. 
  • Respiratory Capacity and Reserve Predict Cell Sensitivity to Mitochondria Inhibitors: Mechanism-Based Markers to Identify Metformin-Responsive Cancers. 
  • Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity. 
  • Retrospective diagnosis of carnitine-acylcarnitine translocase deficiency by acylcarnitine analysis in the proband Guthrie card and enzymatic studies in the parents. 
  • Revelations and revolutions in the understanding of Parkinson's disease. 
  • Revisiting the Warburg Effect: Some Tumors Hold Their Breath. 
  • Rickettsia rickettsii transmission by a lone star tick, North Carolina. 
  • Risuteganib Protects against Hydroquinone-induced Injury in Human RPE Cells. 
  • Role of MAP1B in axonal retrograde transport of mitochondria. 
  • Role of NAD+ and mitochondrial sirtuins in cardiac and renal diseases. 
  • Role of mitofusin 2 mutations in the physiopathology of Charcot-Marie-Tooth disease type 2A. 
  • Role of thyroid hormone in hepatic gene regulation, chromatin remodeling, and autophagy. 
  • Roles of mitochondrial ROS and NLRP3 inflammasome in multiple ozone-induced lung inflammation and emphysema. 
  • Rpl13a small nucleolar RNAs regulate systemic glucose metabolism. 
  • SGK1 signaling promotes glucose metabolism and survival in extracellular matrix detached cells. 
  • SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control. 
  • SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. 
  • SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. 
  • SIRT3 weighs heavily in the metabolic balance: a new role for SIRT3 in metabolic syndrome. 
  • SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder. 
  • SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease. 
  • Scythe: a novel reaper-binding apoptotic regulator. 
  • Seahorse Xfe 24 Extracellular Flux Analyzer-Based Analysis of Cellular Respiration in Caenorhabditis elegans. 
  • Selective defect of in vivo glycolysis in early Huntington's disease striatum. 
  • Sensing Mitochondrial Acetyl-CoA to Tune Respiration. 
  • Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men. 
  • Sequestration of mitochondrial iron by silica particle initiates a biological effect. 
  • Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism. 
  • Severe multisystem pathology, metabolic acidosis, mitochondrial dysfunction, and early death associated with an X-linked AIFM1 variant. 
  • Sex and APOE ε4 genotype modify the Alzheimer's disease serum metabolome. 
  • Sex in fungi. 
  • Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets. 
  • Simultaneous monitoring of tissue PO2 and NADH fluorescence during synaptic stimulation and spreading depression reveals a transient dissociation between oxygen utilization and mitochondrial redox state in rat hippocampal slices. 
  • Single-walled carbon nanotubes increase pandemic influenza A H1N1 virus infectivity of lung epithelial cells. 
  • Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation. 
  • Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling. 
  • Sirtuin-1 expression and activity is diminished in aged liver grafts. 
  • Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. 
  • Skeletal muscle mitochondrial inertia is associated with carnitine acetyltransferase activity and physical function in humans. 
  • Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins. 
  • SnapShot: Mammalian Sirtuins. 
  • Social affiliation predicts mitochondrial DNA copy number in female rhesus macaques. 
  • Sources, mechanisms, and consequences of chemical-induced mitochondrial toxicity. 
  • Spectrophotometry of b-type cytochromes in rat brain in vivo and in vitro. 
  • Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression. 
  • Staphylococcus aureus sepsis induces early renal mitochondrial DNA repair and mitochondrial biogenesis in mice. 
  • Stat3 binds to mtDNA and regulates mitochondrial gene expression in keratinocytes. 
  • Structural and functional properties of cytochrome c oxidases isolated from sharks. 
  • Structure of oxidative- and photo-phosphorylation coupling factor complexes. 
  • Structure of the Trypanosoma brucei p22 protein, a cytochrome oxidase subunit II-specific RNA-editing accessory factor. 
  • Studies on cellular autophagocytosis. Cyclic AMP- and dibutyryl cyclic AMP-stimulated autophagy in rat liver. 
  • Subcellular changes in capillary endothelial cells during repair of hyperoxic lung injury. 
  • Subcellular distribution of transmitter-related enzyme activities in discrete areas of the rat dentate gyrus. 
  • Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes. 
  • Supply-side constraints are insufficient to explain the ontogenetic scaling of metabolic rate in the tobacco Hornworm, Manduca sexta. 
  • Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma. 
  • Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance. 
  • Sustained stress response after oxidative stress in trabecular meshwork cells. 
  • Swimming Exercise and Transient Food Deprivation in Caenorhabditis elegans Promote Mitochondrial Maintenance and Protect Against Chemical-Induced Mitotoxicity. 
  • Synaptic alterations at inner hair cells precede spiral ganglion cell loss in aging C57BL/6J mice. 
  • Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production. 
  • Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity. 
  • THE ABSORPTION SPECTRA OF IRON-FLAVOPROTEINS. 
  • Tamoxifen and tamoxifen ethyl bromide induce apoptosis in acutely damaged mammary epithelial cells through modulation of AKT activity. 
  • Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle. 
  • Targeting Dormant Ovarian Cancer Cells In Vitro and in an In Vivo Mouse Model of Platinum Resistance. 
  • Targeting Tau Mitigates Mitochondrial Fragmentation and Oxidative Stress in Amyotrophic Lateral Sclerosis. 
  • Targeting mitochondria by Zn(II)N-alkylpyridylporphyrins: the impact of compound sub-mitochondrial partition on cell respiration and overall photodynamic efficacy. 
  • Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose. 
  • The Alu neurodegeneration hypothesis: A primate-specific mechanism for neuronal transcription noise, mitochondrial dysfunction, and manifestation of neurodegenerative disease. 
  • The Cell Death Pathway Regulates Synapse Elimination through Cleavage of Gelsolin in Caenorhabditis elegans Neurons. 
  • The Mammalian-Specific Protein Armcx1 Regulates Mitochondrial Transport during Axon Regeneration. 
  • The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. 
  • The Pheromone and Pheromone Receptor Mating-Type Locus Is Involved in Controlling Uniparental Mitochondrial Inheritance in Cryptococcus. 
  • The QPCR assay for analysis of mitochondrial DNA damage, repair, and relative copy number. 
  • The RNase P associated with HeLa cell mitochondria contains an essential RNA component identical in sequence to that of the nuclear RNase P. 
  • The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA. 
  • The Role of Phosphate in Alcohol-Induced Experimental Pancreatitis. 
  • The Role of a Mitochondrial Progesterone Receptor (PR-M) in Progesterone Action. 
  • The TOR signaling cascade regulates gene expression in response to nutrients. 
  • The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality. 
  • The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling. 
  • The administration of renoprotective agents extends warm ischemia in a rat model. 
  • The binding of SLE autoantibodies to mitochondria. 
  • The biological foundation of the genetic association of TOMM40 with late-onset Alzheimer's disease. 
  • The central effectors of cell death in the immune system. 
  • The channel of death. 
  • The contribution of autophagy to lymphocyte survival and homeostasis. 
  • The dielectric constant of phospholipid bilayers and the permeability of membranes to ions. 
  • The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense. 
  • The fine structure of three malignant melanomas of the iris. 
  • The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARγ activation, in 3T3-L1 cells. 
  • The inhibition of human adrenal steroidogenic enzyme activities by suramin. 
  • The insulinomimetic effects of the polar head group of an insulin-sensitive glycophospholipid on pyruvate dehydrogenase in both subcellular and whole cell assays. 
  • The lung is protected from spontaneous inflammation by autophagy in myeloid cells. 
  • The mating type-specific homeodomain genes SXI1 alpha and SXI2a coordinately control uniparental mitochondrial inheritance in Cryptococcus neoformans. 
  • The metabolic co-regulator PGC1α suppresses prostate cancer metastasis. 
  • The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion. 
  • The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion. 
  • The near infrared (NIR) absorption band of cytochrome aa3 in purified enzyme, isolated mitochondria and in the intact brain in situ. 
  • The nuclear receptor-coactivator interaction surface as a target for peptide antagonists of the peroxisome proliferator-activated receptors. 
  • The organization of the pulvinar in the grey squirrel (Sciurus carolinensis). II. Synaptic organization and comparisons with the dorsal lateral geniculate nucleus. 
  • The organophosphate insecticide diazinon and aging: Neurobehavioral and mitochondrial effects in zebrafish exposed as embryos or during aging. 
  • The outer segment serves as a default destination for the trafficking of membrane proteins in photoreceptors. 
  • The oxidation of sulphite in animals systems. 
  • The release of microparticles and mitochondria from RAW 264.7 murine macrophage cells undergoing necroptotic cell death in vitro. 
  • The role of alterations in mitochondrial dynamics and PGC-1α over-expression in fast muscle atrophy following hindlimb unloading. 
  • The role of cytoplasmic deoxycytidine kinase in the mitochondrial effects of the anti-human immunodeficiency virus compound, 2',3'-dideoxycytidine. 
  • The role of mitochondria in immune-mediated disease: the dangers of a split personality. 
  • The role of oxidative damage in mitochondria during aging: a review. 
  • The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. 
  • The tangled circuitry of metabolism and apoptosis. 
  • The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces mitochondrial and nuclear DNA damage in Caenorhabditis elegans. 
  • The urinary proteome infers dysregulation of mitochondrial, lysosomal, and protein reabsorption processes in chronic kidney disease of unknown etiology (CKDu). 
  • The voltage-dependent anion channel is a receptor for plasminogen kringle 5 on human endothelial cells. 
  • Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis. 
  • Therapeutic potential of ReACp53 targeting mutant p53 protein in CRPC. 
  • Thermogenesis in Adipose Tissue Activated by Thyroid Hormone. 
  • Thioredoxin reductase is essential for viability in the fungal pathogen Cryptococcus neoformans. 
  • Three-dimensional reconstruction and quantitative analysis of rat lung type II cells: a computer-based study. 
  • Thyroid hormone (T3) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy. 
  • Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling. 
  • Thyroid hormone receptor and ERRα coordinately regulate mitochondrial fission, mitophagy, biogenesis, and function. 
  • Toll-like receptor 4 mediates mitochondrial DNA damage and biogenic responses after heat-inactivated E. coli. 
  • Transcriptional Regulation of SDHa flavoprotein by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells. 
  • Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes. 
  • Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing. 
  • Transcriptomics in the wild: Hibernation physiology in free-ranging dwarf lemurs. 
  • Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism. 
  • Transmission of Hypervirulence traits via sexual reproduction within and between lineages of the human fungal pathogen cryptococcus gattii. 
  • Tumor oxygenation: a matter of supply and demand. 
  • Two forms of mitochondrial DNA ligase III are produced in Xenopus laevis oocytes. 
  • Tyrosine kinase ETK/BMX is up-regulated in bladder cancer and predicts poor prognosis in patients with cystectomy. 
  • UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation. 
  • UVC-induced mitochondrial degradation via autophagy correlates with mtDNA damage removal in primary human fibroblasts. 
  • Ultrastructural changes in skeletal muscle mitochondria in gram-negative sepsis. 
  • Understanding the genetics of APOE and TOMM40 and role of mitochondrial structure and function in clinical pharmacology of Alzheimer's disease. 
  • Uniparental nuclear inheritance following bisexual mating in fungi. 
  • Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells. 
  • Upstream regulatory role for XIAP in receptor-mediated apoptosis. 
  • VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations. 
  • VDAC2 as a novel target for heart failure: Ca2+ at the sarcomere, mitochondria and SR. 
  • Visualizing Intracellular Organelle and Cytoskeletal Interactions at Nanoscale Resolution on Millisecond Timescales. 
  • Vitamin B1 Helps to Limit Mycobacterium tuberculosis Growth via Regulating Innate Immunity in a Peroxisome Proliferator-Activated Receptor-γ-Dependent Manner. 
  • Vitamin D(3) cryosensitization increases prostate cancer susceptibility to cryoablation via mitochondrial-mediated apoptosis and necrosis. 
  • WIPI1 is a conserved mediator of right ventricular failure. 
  • What happens in lead poisoning? 
  • XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A. 
  • Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP. 
  • Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. 
  • Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like. 
  • [Studies on human porin. V. The expression of "porin31HL" in the plasmalemma is not by cell transformation]. 
  • c-FLIP protects T lymphocytes from apoptosis in the intrinsic pathway. 
  • mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis. 
  • p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase. 
  • β-Cell-specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice. 
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  Keywords of People

  • Cade, William Todd, Professor of Orthopaedic Surgery, Orthopaedic Surgery, Physical Therapy
  • Cartoni, Romain, Assistant Professor of Pharmacology and Cancer Biology, Cell Biology
  • Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
  • Evans, Chantell Skye, Assistant Professor of Cell Biology, Cell Biology
  • Grimsrud, Paul, Assistant Professor in Medicine, Medicine, Endocrinology, Metabolism, and Nutrition
  • Hirschey, Matthew, Associate Professor of Medicine, Cell Biology
  • Jabba, Sairam V., Research Scientist, Anesthesiology
  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Cell Biology
  • Morton, Kate, Student, Nicholas School of the Environment
  • Muoio, Deborah Marie, George Barth Geller Distinguished Professor of Cardiovascular Disease, Pharmacology & Cancer Biology
  • Schwartz-Bloom, Rochelle D., Professor Emeritus of Pharmacology & Cancer Biology, Duke Science & Society
  • Shinohara, Mari L., Professor of Integrative Immunobiology, Cell Biology
  • Turner, Dennis Alan, Professor of Neurosurgery, Biomedical Engineering