Mitogens

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  Subject Areas on Research

  • A prospective study of squamous head and neck carcinoma. Immunologic aberrations in patients who develop recurrent disease. 
  • Abnormalities of chemotactic lymphokine synthesis and mononuclear leukocyte chemotaxis in Wiskott-Aldrich syndrome. 
  • Activated alpha 2-macroglobulin promotes mitogenesis in rat vascular smooth muscle cells by a mechanism that is independent of growth-factor-carrier activity. 
  • Activation of human B cells by phosphorothioate oligodeoxynucleotides. 
  • Activation of human B lymphocytes. VI. Immunoregulation of antibody production by mitogen-induced and naturally occurring cells in normal individuals. 
  • Activation of mitogen-activated protein kinase by epidermal growth factor in hippocampal neurons and neuronal cell lines. 
  • Adolescent nicotine: deficits in immune function. 
  • Biology of small cell lung cancer. 
  • CD2-mediated IL-12-dependent signals render human gamma delta-T cells resistant to mitogen-induced apoptosis, permitting the large-scale ex vivo expansion of functionally distinct lymphocytes: implications for the development of adoptive immunotherapy strategies. 
  • Characterization of human chemotactic lymphokine production induced by mitogens and mixed leukocyte reactions using a new microassay. 
  • Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. I. A description of the technique and of methods for the analysis of colonies. 
  • Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper disks: phenotypic and genotypic analysis of B cell colonies. 
  • Contribution of the VH11 gene family to mitogen-responsive B cell repertoire in C57BL/6 mice. 
  • Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog. 
  • Culture kinetics of glycolytic enzyme induction, glucose utilization, and thymidine incorporation of extended-exposure phytohemagglutinin-stimulated human lymphocytes. 
  • Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells. 
  • DNA and immunoglobulin synthesis by rabbit peripheral blood lymphocytes in vitro: complete and incomplete stimulation. 
  • Depression, urinary free cortisol excretion and lymphocyte function. 
  • Differential effect of B lymphocyte-induced maturation protein (Blimp-1) expression on cell fate during B cell development. 
  • Differential regulation of accessory mitogenic signaling receptors by the T cell antigen receptor. 
  • ETS transcription factors regulate an enhancer activity in the third intron of TNF-alpha. 
  • Effect of deoxyribonucleosides on the hypersensitivity of human peripheral blood lymphocytes to UV-B and UV-C irradiation. 
  • Effects of insulin-like growth factors I and II and insulin on the immortalized hypothalamic GTI-7 cell line. 
  • Effects of murine cytomegalovirus infection on the immune response to a tumor allograft. 
  • Engineering a therapeutic lectin by uncoupling mitogenicity from antiviral activity. 
  • Estrogen-induced mitogenesis of MCF-7 cells does not require the induction of mitogen-activated protein kinase activity. 
  • Exogenous pyruvate prevents stress-evoked suppression of mitogen-stimulated proliferation. 
  • Gamma-phosphate-linked ATP-sepharose for the affinity purification of protein kinases. Rapid purification to homogeneity of skeletal muscle mitogen-activated protein kinase kinase. 
  • Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation. 
  • HIV-1 neutralization profile and plant-based recombinant expression of actinohivin, an Env glycan-specific lectin devoid of T-cell mitogenic activity. 
  • Human malignant and mitogen-transformed cells contain retroviral P15E-related antigen. 
  • Human nasopharyngeal-associated lymphoreticular tissues. Functional analysis of subepithelial and intraepithelial B and T cells from adenoids and tonsils. 
  • Immunization of normal human splenocytes in vitro to produce human monoclonal antibodies to cellular antigens. 
  • Immunologic and hematopoietic alterations by 2,450-MHz electromagnetic radiation. 
  • Impaired lymphocyte function in depressive illness. 
  • Influence of backbone chemistry on immune activation by synthetic oligonucleotides. 
  • Intracellular BH3 Profiling Reveals Shifts in Antiapoptotic Dependency in Human B Cell Maturation and Mitogen-Stimulated Proliferation. 
  • Lack of generation of killer cells in the mixed lymphocyte reaction between mitogen-stimulated and unstimulated autologous lymphocytes. 
  • Leprosy in a mangabey monkey--naturally acquired infection. 
  • Mechanisms of corticosteroid action on lymphocyte subpopulations. IV. Effects of in vitro hydrocortisone on naturally occuring and mitogen-induced suppressor cells in man. 
  • Mechanisms of corticosteroid action on lymphocyte subpopulations. V. Effects of in vivo hydrocortisone on the circulatory kinetics and function of naturally occuring and mitogen-induced suppressor cells in man. 
  • Metabolic cooperation between vascular endothelial cells and smooth muscle cells in co-culture: changes in low density lipoprotein metabolism. 
  • Mitogen-induced B-cell proliferation activates Chk2-dependent G1/S cell cycle arrest. 
  • Mitogenesis, cell migration, and loss of focal adhesions induced by tenascin-C interacting with its cell surface receptor, annexin II. 
  • Mitogenic and adhesive effects of tenascin-C on human hematopoietic cells are mediated by various functional domains. 
  • Mitogenic effect of neuropeptide Y in rat vascular smooth muscle cells. 
  • Mitogenic stimulation of human B lymphocytes by the mannose-specific adhesin on Escherichia coli type 1 fimbriae. 
  • Mitogens stimulate the rapid nuclear to cytosolic translocation of tristetraprolin, a potential zinc-finger transcription factor. 
  • NOV (CCN3) regulation in the growth plate and CCN family member expression in cartilage neoplasia. 
  • Neonatal chlorpyrifos administration elicits deficits in immune function in adulthood: a neural effect? 
  • New regulators of vertebrate appendage regeneration. 
  • Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities. 
  • Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish. 
  • Overexpression of G protein-coupled receptor kinase-2 in smooth muscle cells attenuates mitogenic signaling via G protein-coupled and platelet-derived growth factor receptors. 
  • Overexpression of G protein-coupled receptor kinase-2 in smooth muscle cells reduces neointimal hyperplasia. 
  • Phosphorylation of tristetraprolin, a potential zinc finger transcription factor, by mitogen stimulation in intact cells and by mitogen-activated protein kinase in vitro. 
  • Platelet-derived growth factor enhances granulosa cell luteinizing hormone receptor induction by follicle-stimulating hormone and serum. 
  • Promoter analysis of Zfp-36, the mitogen-inducible gene encoding the zinc finger protein tristetraprolin. 
  • Properties of mouse leukemia viruses. XIX. Effective antibody therapy of AKR leukemia occurs independently of virus neutralization and produces long-term changes in the virus status of the thymus. 
  • Regulation of IgE synthesis: introduction. 
  • Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle. 
  • Sex steroid hormones enhance immune function in male and female Siberian hamsters. 
  • Studies of T-lymphocytes in preleukemic disorders and acute nonlymphocytic leukemia: in vitro radiosensitivity, mitogenic responsiveness, colony formation, and enumeration of lymphocytic subpopulations. 
  • Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation. 
  • T lymphocyte depletion of human peripheral blood and bone marrow using monoclonal antibodies and magnetic microspheres. 
  • TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice. 
  • The functions and measurement of human B- and T-lymphocytes. 
  • The protein synthetic surge in response to mitogen triggers high glycolytic enzyme levels in human lymphocytes and occurs prior to DNA synthesis. 
  • The role of surface ig binding in the activation of human B cells by phosphorothioate oligodeoxynucleotides. 
  • Toxocara antigen and mitogen-induced lymphocyte blastogenesis for diagnosis of visceral larva migrans: clinical and experimental findings in macaques and human beings. 
  • Transplantation of thymus tissue in complete DiGeorge syndrome. 
  • Unusual clinical and immunologic manifestations of transplacentally acquired maternal T cells in severe combined immunodeficiency. 
  • Wnt signaling: an embarrassment of receptors. 
  • Zinc and immunocompetence in elderly people: effects of zinc supplementation for 3 months. 
  • [Characteristics of cells producing immune interferon]. 
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  Keywords of People

  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Professor of Pediatrics, in the School of Medicine, Immunology
  • Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
  • Kelsoe, Garnett H., James B. Duke Professor of Immunology, Immunology