Models, Cardiovascular

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  Subject Areas on Research

  • 3D Heart: a new visual training method for electrocardiographic analysis. 
  • A biophysical model for cardiac microimpedance measurements. 
  • A biphasic, anisotropic model of the aortic wall. 
  • A brief history of tissue models for cardiac electrophysiology. 
  • A cardiac phantom and pulsatile flow pump for magnetic resonance imaging studies. 
  • A caudal proliferating growth center contributes to both poles of the forming heart tube. 
  • A computer model of normal conduction in the human atria. 
  • A critique of impedance measurements in cardiac tissue. 
  • A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration. 
  • A dynamic model forecasting myocardial infarct size before, during, and after reperfusion therapy: an ASSENT-2 ECG/VCG substudy. 
  • A dynamic three-dimensional display of ventricular excitation and the generation of the vector and electrocardiogram. 
  • A finite volume model of cardiac propagation. 
  • A flexible method for simulating cardiac conduction in three-dimensional complex geometries. 
  • A focal stress gradient-dependent mass transfer mechanism for atherogenesis in branching arteries. 
  • A microstructural model of reentry arising from focal breakthrough at sites of source-load mismatch in a central region of slow conduction. 
  • A microstructurally motivated model of the mechanical behavior of tissue engineered blood vessels. 
  • A modified four-vessel occlusion model for inducing incomplete forebrain ischemia in rats. 
  • A new view of convective-diffusive transport processes in the arterial intima. 
  • A novel survival model of cardioplegic arrest and cardiopulmonary bypass in rats: a methodology paper. 
  • A novel ultrasound technique to estimate right ventricular geometry during fibrillation. 
  • A novel, data-driven conceptualization for critical left heart obstruction. 
  • A numerical scheme for modeling wavefront propagation on a monolayer of arbitrary geometry. 
  • A piece-wise non-linear elastic stress expression of human and pig coronary arteries tested in vitro. 
  • A planar slab bidomain model for cardiac tissue. 
  • A possible subcellular structure based on the macroscopic cardiac source. 
  • A prototype inverse solution in one-dimension to find the origin of excitation, strand radius, intracellular resistivity, or distance from the surface. 
  • A pumping intravascular artificial lung with active mixing. 
  • A resistor interpretation of general anisotropic cardiac tissue. 
  • A simulation study evaluating the performance of high-density electrode arrays on myocardial tissue. 
  • A space-time adaptive method for simulating complex cardiac dynamics. 
  • A structural framework for interpretation of four-electrode microimpedance spectra in cardiac tissue. 
  • A theoretical analysis of acute ischemia and infarction using ECG reconstruction on a 2-D model of myocardium. 
  • A three-dimensional finite element model of human atrial anatomy: new methods for cubic Hermite meshes with extraordinary vertices. 
  • A three-dimensional finite element model of radiofrequency ablation with blood flow and its experimental validation. 
  • A time-of-flight method of measuring flow velocity by magnetic resonance imaging. 
  • A two-current model for the dynamics of cardiac membrane. 
  • Accelerated intravenous dosing of recombinant tissue-type plasminogen activator causes rapid but unstable reperfusion in a canine model of acute myocardial infarction. 
  • Active response of a one-dimensional cardiac model with gap junctions to extracellular stimulation. 
  • Acute coronary syndromes in the GUSTO-IIb trial: prognostic insights and impact of recurrent ischemia. The GUSTO-IIb Investigators. 
  • Acute renal failure following cardiac surgery. 
  • Adaptive Mesh Refinement and Adaptive Time Integration for Electrical Wave Propagation on the Purkinje System. 
  • Advective transport of nitric oxide in a mathematical model of the afferent arteriole. 
  • Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. 
  • Allometric scaling of decompression sickness risk in terrestrial mammals; cardiac output explains risk of decompression sickness. 
  • An electrocardiographic sign of ischemic preconditioning. 
  • An in vitro study of pulsatile fluid dynamics in intracranial aneurysm models treated with embolic coils and flow diverters. 
  • An international model to predict recurrent cardiovascular disease. 
  • An investigation of particle flow through capillary models with the resistive pulse technique. 
  • An ionically based mapping model with memory for cardiac restitution. 
  • Analysis of oxygen transport in a diffusion-limited model of engineered heart tissue. 
  • Analysis of pulsed wave Doppler ultrasound spectra obtained from a model intracoronary catheter. 
  • Analysis of the effects of oxygen supply and demand on hypoxic fraction in tumors. 
  • Analytical model of extracellular potentials in a tissue slab with a finite bath. 
  • Angiogenesis: an adaptive dynamic biological patterning problem. 
  • Anisotropy, fiber curvature, and bath loading effects on activation in thin and thick cardiac tissue preparations: simulations in a three-dimensional bidomain model. 
  • Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation. 
  • Apoptosis during coronary artery orifice development in the chick embryo. 
  • Arterial windkessel parameter estimation: a new time-domain method. 
  • Assessing the incremental predictive performance of novel biomarkers over standard predictors. 
  • Assessment of coronary reperfusion after thrombolysis with a model combining myoglobin, creatine kinase-MB, and clinical variables. TAMI-7 Study Group. Thrombolysis and Angioplasty in Myocardial Infarction-7. 
  • Assessment of the Frank-Starling relationship by two-dimensional echocardiography. 
  • Association between secondary flow in models of the aorto-celiac junction and subendothelial macrophages in the normal rabbit. 
  • Augmentation of mortality risk discriminating power of left ventricular ejection fraction by measures of nonuniformity in systolic emptying on radionuclide ventriculography. 
  • Automated production of contour maps for electrophysiology. I. Problem definition, solution strategy, and specification of geometric model. 
  • Automated production of contour maps for electrophysiology. II. Triangulation, verification, and organization of the geometric model. 
  • Automated production of contour maps for electrophysiology. III. Construction of contour maps. 
  • Automatic grading of retinal vessel caliber. 
  • Bayesian analysis of data from radionuclide angiocardiograms for diagnosis of coronary artery disease. 
  • Bayesian analysis of fiber impedance measurements. 
  • Beta-adrenergic axis and heart disease. 
  • Bipolar stimulation of a three-dimensional bidomain incorporating rotational anisotropy. 
  • Bistability and correlation with arrhythmogenesis in a model of the right atrium. 
  • Blockade of rabbit atrial sodium channels by lidocaine. Characterization of continuous and frequency-dependent blocking. 
  • Blockade of the extracellular signal-regulated kinase pathway by U0126 attenuates neuronal damage following circulatory arrest. 
  • Calculating endocardial potentials from epicardial potentials measured during external stimulation. 
  • Cardiac mechanics: basic and clinical contemporary research. 
  • Cardiac microimpedance measurement in two-dimensional models using multisite interstitial stimulation. 
  • Cardiac phantom evaluation of simultaneously acquired dual-isotope rest thallium-201/stress technetium-99m SPECT images. 
  • Cardiac propagation simulation. 
  • Cardiac surgery risk models: a position article. 
  • Cardiac transient outward potassium current: a pulse chemistry model of frequency-dependent properties. 
  • Cardiac ultrasound phantom using a porcine heart model. 
  • Cardiogenic shock in patients with acute ischemic syndromes with and without ST-segment elevation. 
  • Cardiomyocyte cultures with controlled macroscopic anisotropy: a model for functional electrophysiological studies of cardiac muscle. 
  • Cataloguing the geometry of the human coronary arteries: a potential tool for predicting risk of coronary artery disease. 
  • Cell size and communication: role in structural and electrical development and remodeling of the heart. 
  • Cerebral blood flow, blood volume, and brain tissue hematocrit during isovolemic hemodilution with hetastarch in rats. 
  • Cerebral oxygenation and optimal vascular brain organization. 
  • Characterization of a sudden expansion flow chamber to study the response of endothelium to flow recirculation. 
  • Clinical assessment of diastolic function. 
  • Comparison among different high porosity stent configurations: hemodynamic effects of treatment in a large cerebral aneurysm. 
  • Comparison of Acoustic Radiation Force Impulse Imaging Derived Carotid Plaque Stiffness With Spatially Registered MRI Determined Composition. 
  • Comparison of model-based and expert-rule based electrocardiographic identification of the culprit artery in patients with acute coronary syndrome. 
  • Complexity of the autonomic heart rate control in coronary artery occlusion in patients with and without prior myocardial infarction. 
  • Comprehensive metabolic modeling of multiple 13C-isotopomer data sets to study metabolism in perfused working hearts. 
  • Computational Fluid Dynamics and Additive Manufacturing to Diagnose and Treat Cardiovascular Disease. 
  • Computational fluid dynamics of left ventricular ejection. 
  • Computer simulation as a component of catheter-based training. 
  • Computer simulations of activation in an anatomically based model of the human ventricular conduction system. 
  • Computer-assisted modeling of blood-flow: theoretical evidence for the existence of optimal flow wave patterns. 
  • Condition for alternans and its control in a two-dimensional mapping model of paced cardiac dynamics. 
  • Condition for alternans and stability of the 1:1 response pattern in a "memory" model of paced cardiac dynamics. 
  • Contribution of activation-inactivation dynamics to the impairment of relaxation in hypoxic cat papillary muscle. 
  • Control of electrical alternans in simulations of paced myocardium using extended time-delay autosynchronization. 
  • Correspondence of low mean shear and high harmonic content in the porcine iliac arteries. 
  • Current flow patterns in two-dimensional anisotropic bisyncytia with normal and extreme conductivities. 
  • Data for cardiovascular modeling. 
  • Defibrillation and the upper limit of vulnerability to fibrillation in a transthoracic guinea pig model. 
  • Detection of left ventricular thrombus by delayed-enhancement cardiovascular magnetic resonance prevalence and markers in patients with systolic dysfunction. 
  • Deterioration of regional wall motion immediately after coronary artery bypass graft surgery is associated with long-term major adverse cardiac events. 
  • Development and evaluation of multi-marker risk scores for clinical prognosis. 
  • Development of a model of the coronary arterial tree for the 4D XCAT phantom. 
  • Development of an intravascular lung assist device. 
  • Diastolic anisotropic properties of the left ventricle in the conscious dog. 
  • Diastolic coronary resistance and capacitance are independent of the duration of diastole. 
  • Discordance between patient-predicted and model-predicted life expectancy among ambulatory patients with heart failure. 
  • Distance from the coronary ostium to the culprit lesion in acute ST-elevation myocardial infarction and its implications regarding the potential prevention of proximal plaque rupture. 
  • Distribution of shear stress over smooth muscle cells in deformable arterial wall. 
  • Does the degree of coarctation of the aorta influence wall shear stress focal heterogeneity? 
  • Dose response of angiogenesis to basic fibroblast growth factor in rat corneal pocket assay: I. Experimental characterizations. 
  • Dose response of angiogenesis to basic fibroblast growth factor in rat corneal pocket assay: II. Numerical simulations. 
  • Dynamic internal compliance of a vascular prosthesis. 
  • Dynamical mechanism for subcellular alternans in cardiac myocytes. 
  • Dynamics of bubble oscillation in constrained media and mechanisms of vessel rupture in SWL. 
  • Effect of door-to-balloon time on mortality in patients with ST-segment elevation myocardial infarction. 
  • Effect of fluid shear stress on the permeability of the arterial endothelium. 
  • Effect of gap junction distribution on impulse propagation in a monolayer of myocytes: a model study. 
  • Effect of junctional resistance on source-strength in a linear cable. 
  • Effect of microscopic and macroscopic discontinuities on the response of cardiac tissue to defibrillating (stimulating) currents. 
  • Effect of nonuniform interstitial space properties on impulse propagation: a discrete multidomain model. 
  • Effect of pentoxifylline on the flow of polymorphonuclear leukocytes through a model capillary. 
  • Effect of resistive barrier location on the relationship between T-wave alternans and cellular repolarization alternans: a 1-D modeling study. 
  • Effect of stenosis inlet geometry on shear rates of blood flow in the upstream region. 
  • Effects of cardiac motion on right coronary artery hemodynamics. 
  • Effects of electroporation on transmembrane potential induced by defibrillation shocks. 
  • Effects of magnesium supplementation in a porcine model of myocardial ischemia and reperfusion. 
  • Effects of severity and location of stenosis on the hemodynamics in human aorta and its branches. 
  • Effects of turbulence on signal intensity in gradient echo images. 
  • Efficient fully implicit time integration methods for modeling cardiac dynamics. 
  • Efficient simulation of three-dimensional anisotropic cardiac tissue using an adaptive mesh refinement method. 
  • Electrocardiogram sources in a 2-dimensional anisotropic activation model. 
  • Electrocardiographic Early Repolarization: A Scientific Statement From the American Heart Association. 
  • Electrocardiographic QRS duration and the risk of congestive heart failure: the Framingham Heart Study. 
  • Electrocardiographic inverse solution for ectopic origin of excitation in two-dimensional propagation model. 
  • Electrode systems for measuring cardiac impedances using optical transmembrane potential sensors and interstitial electrodes--theoretical design. 
  • Electrophysiological effects of remodeling cardiac gap junctions and cell size: experimental and model studies of normal cardiac growth. 
  • Electrophysiological interaction through the interstitial space between adjacent unmyelinated parallel fibers. 
  • Electroporation and shock-induced transmembrane potential in a cardiac fiber during defibrillation strength shocks. 
  • Electrotonic influences on action potential duration dispersion in small hearts: a simulation study. 
  • Enhancement of cardiac function by cyclocreatine in models of cardiopulmonary bypass. 
  • Epicardial cardiac source-field behavior. 
  • Estimating the 95% effective defibrillation dose. 
  • Estimation of cardiac bidomain parameters from extracellular measurement: two dimensional study. 
  • Estimation of cardiac conduction velocities using small data sets. 
  • Estimation of myocardial blood flow for longitudinal studies with 13N-labeled ammonia and positron emission tomography. 
  • Ethacizin blockade of calcium channels: a test of the guarded receptor hypothesis. 
  • Evaluating strict and conventional left bundle branch block criteria using electrocardiographic simulations. 
  • Evaluation of artery visualizations for heart disease diagnosis. 
  • Evaluation of flow through simulated vascular stenoses with gradient echo magnetic resonance imaging. 
  • Evaluation of right and left ventricular diastolic filling. 
  • Experimental cardiac tachyarrhythmias in guinea pigs. 
  • Experimental determination of wall shear rate in canine carotid arteries perfused in vitro. 
  • Experimental evidence of improved transthoracic defibrillation with electroporation-enhancing pulses. 
  • Experimental verification of theoretical predictions concerning the optimum defibrillation waveform. 
  • Exploring reentrant arrhythmias with numerical experiments: generic properties and model complexity. 
  • Extracellular (volume conductor) effect on adjoining cardiac muscle electrophysiology. 
  • Extracellular discontinuities in cardiac muscle: evidence for capillary effects on the action potential foot. 
  • FGF23 induces left ventricular hypertrophy. 
  • Factors affecting ventricular volumes determined by a count-based equilibrium method. 
  • Feasibility of cardiac microimpedance measurement using multisite interstitial stimulation. 
  • Feedback-control induced pattern formation in cardiac myocytes: a mathematical modeling study. 
  • Fetal XCMR: a numerical phantom for fetal cardiovascular magnetic resonance imaging. 
  • Field stimulation of cardiac fibers with random spatial structure. 
  • Finite element modeling of embolic coil deployment: multifactor characterization of treatment effects on cerebral aneurysm hemodynamics. 
  • Finite element modelling of pulsatile blood flow in idealized model of human aortic arch: study of hypotension and hypertension. 
  • Finite volume stiffness matrix for solving anisotropic cardiac propagation in 2-D and 3-D unstructured meshes. 
  • Finite-element analysis of balloon angioplasty. 
  • Flattening the abdominal aortic tree for effective visualization. 
  • Flow diverter effect on cerebral aneurysm hemodynamics: an in vitro comparison of telescoping stents and the Pipeline. 
  • Fluid dynamics of aortic stenosis: mechanisms for the presence of subvalvular pressure gradients. 
  • Frequency dependence of the cardiac threshold to alternating current between 10 Hz and 160 Hz. 
  • Genesis of QRS in the ruminant: graphic simulation. 
  • Green's function methods for analysis of oxygen delivery to tissue by microvascular networks. 
  • Harmonic spatial coherence imaging: an ultrasonic imaging method based on backscatter coherence. 
  • Harnessing Macrophages for Vascularization in Tissue Engineering. 
  • Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative. 
  • Heart reduction surgery: an analysis of the impact on cardiac function. 
  • Hemodynamic parameters and early intimal thickening in branching blood vessels. 
  • Hemodynamics simulation and identification of susceptible sites of atherosclerotic lesion formation in a model abdominal aorta. 
  • How do red blood cells dilate blood vessels? 
  • Identification of High-Risk Plaques Destined to Cause Acute Coronary Syndrome Using Coronary Computed Tomographic Angiography and Computational Fluid Dynamics. 
  • Identification of cardiac rhythm features by mathematical analysis of vector fields. 
  • Identification of electrocardiographic criteria for diagnosis of right ventricular hypertrophy due to mitral stenosis. 
  • Impact of endovascular simulator training on vascular surgery as a career choice in medical students. 
  • Improved aortic enhancement in CT angiography using slope-based triggering with table speed optimization: a pilot study. 
  • Improved cardiac anthropomorphic phantom. 
  • Improved survival of patients undergoing palliation of hypoplastic left heart syndrome: lessons learned from 115 consecutive patients. 
  • Improving on the diagnostic characteristics of echocardiography for pulmonary hypertension. 
  • Improving temporal resolution of pulmonary perfusion imaging in rats using the partially separable functions model. 
  • In vitro analysis of jets by Doppler colour flow imaging: the importance of time to maximum jet area. 
  • Inclusion of junction elements in a linear cardiac model through secondary sources: application to defibrillation. 
  • Incorporating histology into a 3D microscopic computer model of myocardium to study propagation at a cellular level. 
  • Incorporation of a left ventricle finite element model defining infarction into the XCAT imaging phantom. 
  • Increase in collateral blood flow following repeated coronary artery occlusion and nitroglycerin administration. 
  • Increased interstitial loading reduces the effect of microstructural variations in cardiac tissue. 
  • Increasing the computational efficiency of a bidomain model of defibrillation using a time-dependent activating function. 
  • Incremental value of the exercise test for diagnosing the presence or absence of coronary artery disease. 
  • Individual and combined effects of shear stress magnitude and spatial gradient on endothelial cell gene expression. 
  • Influence of dynamic gap junction resistance on impulse propagation in ventricular myocardium: a computer simulation study. 
  • Influence of progressive central hypovolemia on Hölder exponent distributions of cardiac interbeat intervals. 
  • Influence of shock strength and timing on induction of ventricular arrhythmias in dogs. 
  • Influence of the passive anisotropic properties on directional differences in propagation following modification of the sodium conductance in human atrial muscle. A model of reentry based on anisotropic discontinuous propagation. 
  • Inhibition of intimal hyperplasia by direct thrombin inhibitors in an animal vein bypass model. 
  • Interaction of wall shear stress magnitude and gradient in the prediction of arterial macromolecular permeability. 
  • Interactions between extracellular stimuli and excitation waves in an atrial reentrant loop. 
  • Intracardiac catheter 2-D arrays on a silicon substrate. 
  • Intravascular food reward. 
  • Ischemic modulation of vulnerable period and the effects of pharmacological treatment of ischemia-induced arrhythmias: a simulation study. 
  • Kidney in hypertension: guyton redux. 
  • Kinetics of interaction of the lidocaine metabolite glycylxylidide with the cardiac sodium channel. Additive blockade with lidocaine. 
  • Large sample test of defibrillation waveform sensitivity. 
  • Left ventricular wall motion analysis using real-time three-dimensional ultrasound. 
  • Linear algebraic transformations of the bidomain equations: implications for numerical methods. 
  • Load-independent analysis of a pulsatile right ventricular assist device. 
  • Loading effect of fibroblast-myocyte coupling on resting potential, impulse propagation, and repolarization: insights from a microstructure model. 
  • Locating a catheter transducer in a three-dimensional ultrasound imaging field. 
  • Long term model for evaluation of myocardial metabolic recovery following global ischemia. 
  • Long-term survival of patients with ischemic cardiomyopathy treated by coronary artery bypass grafting versus medical therapy. 
  • Low dose heparin therapy: in vitro verification of antithrombotic effect. 
  • MRXCAT: Realistic numerical phantoms for cardiovascular magnetic resonance. 
  • Magnesium deficiency prolongs myocardial stunning in an open-chest swine model. 
  • Magnetic susceptibility anisotropy of myocardium imaged by cardiovascular magnetic resonance reflects the anisotropy of myocardial filament α-helix polypeptide bonds. 
  • Mathematical modeling of electrical activity of the heart. 
  • Measurement of left ventricular volume in normal and volume-overloaded canine hearts. 
  • Measurement of retinal blood vessel width using computerized image analysis. 
  • Measurement of the aorta and its branches with helical CT. 
  • Measurement of the transverse strain tensor in the coronary arterial wall from clinical intravascular ultrasound images. 
  • Mechanical determinants of myocardial oxygen consumption in conscious dogs. 
  • Mechanical versus chemical thrombolysis: an in vitro differentiation of thrombolytic mechanisms. 
  • Mechanism of cardiac defibrillation. A different point of view. 
  • Mechanism of origin of conduction disturbances in aging human atrial bundles: experimental and model study. 
  • Mechanisms by which AC leakage currents cause complete hemodynamic collapse without inducing fibrillation. 
  • Mechanotransduction mechanisms for intraventricular diastolic vortex forces and myocardial deformations: part 1. 
  • Membrane currents underlying bursting pacemaker activity and spike frequency adaptation in invertebrates. 
  • Microelectrode study of the genesis of the monophasic action potential by contact electrode technique. 
  • Microheterogeneity-induced conduction slowing and wavefront collisions govern macroscopic conduction behavior: A computational and experimental study. 
  • Microscopic variations in interstitial and intracellular structure modulate the distribution of conduction delays and block in cardiac tissue with source-load mismatch. 
  • Microvolt T wave alternans inducibility in normal newborn puppies: effects of development. 
  • Misconceptions in reporting oxygen saturation. 
  • Model predictions of deformation, embolization and permeability of partially obstructive blood clots under variable shear flow. 
  • Model systems for the study of heart development and disease. Cardiac neural crest and conotruncal malformations. 
  • Model-based estimation of cardiovascular repolarization features: ischaemia detection and PTCA monitoring. 
  • Modeling an Excitable Biosynthetic Tissue with Inherent Variability for Paired Computational-Experimental Studies. 
  • Modeling atrial arrhythmias: impact on clinical diagnosis and therapies. 
  • Modeling dynamics in diseased cardiac tissue: Impact of model choice. 
  • Modeling the Pulse Signal by Wave-Shape Function and Analyzing by Synchrosqueezing Transform. 
  • Modeling the adaptive permeability response of porcine iliac arteries to acute changes in mural shear. 
  • Modelling cardiac fibroblasts: interactions with myocytes and their impact on impulse propagation. 
  • Modelling induction of a rotor in cardiac muscle by perpendicular electric shocks. 
  • Modelling the periodicity of cardiac muscle. 
  • Models for coronary pressure-flow relationships. 
  • Modification of a cylindrical bidomain model for cardiac tissue. 
  • Modifications of the cardiac double-layer source arising from interstitial potentials. 
  • Modulation of conduction velocity by nonmyocytes in the low coupling regime. 
  • Multifractal and nonlinear assessment of autonomous nervous system response during transient myocardial ischaemia. 
  • Multisite interstitial stimulation for cardiac micro-impedance measurements. 
  • Myocardial viability mapping by magnetic resonance-based multiparametric systolic strain analysis. 
  • Myofiber angle distributions in the ovine left ventricle do not conform to computationally optimized predictions. 
  • NO and superoxide: opposite ends of the seesaw in cardiac contractility. 
  • Near-infrared spectroscopy. Clinical applications. 
  • Need for centers to care for patients with acute coronary syndromes. 
  • New perspectives in hypertension research. Potentials of vascular biology. 
  • Non-linear dynamic analysis of the cardiac rhythm during transient myocardial ischemia. 
  • Non-uniform dispersion of the source-sink relationship alters wavefront curvature. 
  • Normal and pathological NCAT image and phantom data based on physiologically realistic left ventricle finite-element models. 
  • Normal and shear stresses influence the spatial distribution of intracellular adhesion molecule-1 expression in human umbilical vein endothelial cells exposed to sudden expansion flow. 
  • Numerical investigation and prediction of atherogenic sites in branching arteries. 
  • On the Functional Role of Valve Interstitial Cell Stress Fibers: A Continuum Modeling Approach. 
  • One-dimensional model of cardiac defibrillation. 
  • Pathophysiological role of changing atrial size and pressure in modulation of atrial natriuretic factor during evolving experimental heart failure. 
  • Percolation, morphogenesis, and burgers dynamics in blood vessels formation. 
  • Period-doubling bifurcation to alternans in paced cardiac tissue: crossover from smooth to border-collision characteristics. 
  • Perturbations in hyperthermia temperature distributions associated with counter-current flow: numerical simulations and empirical verification. 
  • Physical principles governing the interrelationships of pressure, flow and volume in collapsible tubes. 
  • Physiology of cardiac tamponade and paradoxical pulse in conscious dogs. 
  • Pitfalls in the determination of absolute dimensions using angiographic catheters as calibration devices in quantitative angiography. 
  • Porcine carotid arterial material property alterations with induced atheroma: an in vivo study. 
  • Poststenotic signal loss in MR angiography: effects of echo time, flow compensation, and fractional echo. 
  • Potential distribution in three-dimensional periodic myocardium--Part I: Solution with two-scale asymptotic analysis. 
  • Potential distribution in three-dimensional periodic myocardium--Part II: Application to extracellular stimulation. 
  • Predicting patterns of epicardial potentials during ventricular fibrillation. 
  • Predicting the potential gradient field in ventricular fibrillation from shocks delivered in paced rhythm. 
  • Prediction of rehospitalization and death in severe heart failure by physicians and nurses of the ESCAPE trial. 
  • Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage. Thrombolytic Predictive Instrument (TPI) Project results. 
  • Propagating depolarization in anisotropic human and canine cardiac muscle: apparent directional differences in membrane capacitance. A simplified model for selective directional effects of modifying the sodium conductance on Vmax, tau foot, and the propagation safety factor. 
  • Propagation in cardiac tissue adjacent to connective tissue: two-dimensional modeling studies. 
  • Propagation versus delayed activation during field stimulation of cardiac muscle. 
  • Properties of discontinuous anisotropic propagation at a microscopic level. 
  • Pulsatile blood flow effects on temperature distribution and heat transfer in rigid vessels. 
  • Qualitative blood flow differentiation: depiction of a left to right cardiac shunt across a ventricular septal defect using electron-beam computed tomography. 
  • Quantification of myocardial hypoperfusion with 99m Tc-sestamibi in patients undergoing prolonged coronary artery balloon occlusion. 
  • Quantitative mapping of hemodynamics in the lung, brain, and dorsal window chamber-grown tumors using a novel, automated algorithm. 
  • RV functional imaging: 3-D echo-derived dynamic geometry and flow field simulations. 
  • RV instantaneous intraventricular diastolic pressure and velocity distributions in normal and volume overload awake dog disease models. 
  • Random nature of fibrillation leads to the probabilistic nature of defibrillation. 
  • Rate-dependent propagation of cardiac action potentials in a one-dimensional fiber. 
  • Real-time three-dimensional echocardiography to construct clinically ready, load-independent indices of myocardial contractile performance. 
  • Recent advances in renal hemodynamics: insights from bench experiments and computer simulations. 
  • Reduction of tissue injury in shock-wave lithotripsy by using an acoustic diode. 
  • Reflection after delayed excitation in a computer model of a single fiber. 
  • Region specific modeling of cardiac muscle: comparison of simulated and experimental potentials. 
  • Regional material property alterations in porcine femoral arteries with atheroma development. 
  • Regional structure-function relationships in mouse aortic valve tissue. 
  • Regression modelling strategies for improved prognostic prediction. 
  • Relating extracellular potentials and their derivatives to anisotropic propagation at a microscopic level in human cardiac muscle. Evidence for electrical uncoupling of side-to-side fiber connections with increasing age. 
  • Relation between near-wall residence times of monocytes and early lesion growth in the rabbit aorto-celiac junction. 
  • Relation between non-uniform hemodynamics and sites of altered permeability and lesion growth at the rabbit aorto-celiac junction. 
  • Relationship between extracellular T-wave height, T-wave alternans amplitude, and tissue action potential alternans: a 1-dimensional computer modeling study. 
  • Report of the first virtual visualization of the reconstructed electrocardiographic display symposium. 
  • Reproducing cardiac restitution properties using the Fenton-Karma membrane model. 
  • Restitution in mapping models with an arbitrary amount of memory. 
  • Retinal arteriolar changes: intermediate pathways linking early life exposures to cardiovascular disease? 
  • Revised formulas for summarizing retinal vessel diameters. 
  • Right and left ventricular diastolic pressure-volume relations: a comprehensive review. 
  • Right ventricular diastolic function in canine models of pressure overload, volume overload, and ischemia. 
  • Right ventricular diastolic relaxation in conscious dog models of pressure overload, volume overload, and ischemia. 
  • Right ventricular volumes are rarely right and are right hard to do. 
  • Risk index for predicting in-hospital mortality for cardiac valve surgery. 
  • Role of Nitric Oxide Carried by Hemoglobin in Cardiovascular Physiology: Developments on a Three-Gas Respiratory Cycle. 
  • Role of Volume Redistribution in the Congestion of Heart Failure. 
  • Role of deformable cancer cells on wall shear stress-associated-VEGF secretion by endothelium in microvasculature. 
  • Role of repulsive factors in vascularization dynamics. 
  • Roles of collateral arterial flow and ischemic preconditioning in protection of acutely ischemic myocardium. 
  • Sensor spacing affects the tissue impedance spectra of rabbit ventricular epicardium. 
  • Sex-specific computational models for blood pressure regulation in the rat. 
  • Sex-specific long-term blood pressure regulation: Modeling and analysis. 
  • Significant left ventricular contribution to right ventricular systolic function. 
  • Simulating the electrical behavior of cardiac tissue using the bidomain model. 
  • Simulation and prediction of functional block in the presence of structural and ionic heterogeneity. 
  • Simulation of propagation along a cylindrical bundle of cardiac tissue--I: Mathematical formulation. 
  • Simulation of propagation along a cylindrical bundle of cardiac tissue--II: Results of simulation. 
  • Simulation of use-dependent uptake of ion channel blocking agents by excitable membranes. 
  • Single dose of glutamine enhances myocardial tissue metabolism, glutathione content, and improves myocardial function after ischemia-reperfusion injury. 
  • Sinus Node Dysfunction and Atrial Fibrillation: A Reversible Phenomenon? 
  • Smaller birth size is associated with narrower retinal arterioles in early adolescence. 
  • Sodium channel kinetic changes that produce Brugada syndrome or progressive cardiac conduction system disease. 
  • Spatial comparison between wall shear stress measures and porcine arterial endothelial permeability. 
  • Spatial heterogeneity of restitution properties and the onset of alternans. 
  • Stability of rotors and focal sources for human atrial fibrillation: focal impulse and rotor mapping (FIRM) of AF sources and fibrillatory conduction. 
  • Statistical analysis of signals from an intracavitary probe in a diseased heart. 
  • Statistical hemodynamics: a tool for evaluating the effect of fluid dynamic forces on vascular biology in vivo. 
  • Structural adaptation and heterogeneity of normal and tumor microvascular networks. 
  • Suppression of large intraluminal bubble expansion in shock wave lithotripsy without compromising stone comminution: refinement of reflector geometry. 
  • Surgically implantable magnetic resonance angiography coils improve resolution to allow visualization of blood flow dynamics. 
  • System identification of dynamic closed-loop control of total peripheral resistance by arterial and cardiopulmonary baroreceptors. 
  • TRM Forum on Computer Simulation and Experimental Assessment of Cardiac Function. 
  • Teaching cardiovascular assessment. 
  • The Cardiovascular Continuum extended: aging effects on the aorta and microvasculature. 
  • The GUSTO trial and the open artery theory. 
  • The Society of Thoracic Surgeons 2008 cardiac surgery risk models: part 1--coronary artery bypass grafting surgery. 
  • The Society of Thoracic Surgeons 2008 cardiac surgery risk models: part 2--isolated valve surgery. 
  • The Society of Thoracic Surgeons 2008 cardiac surgery risk models: part 3--valve plus coronary artery bypass grafting surgery. 
  • The Society of Thoracic Surgeons Mitral Repair/Replacement Composite Score: A Report of The Society of Thoracic Surgeons Quality Measurement Task Force. 
  • The cardiac vulnerable period and reentrant arrhythmias: targets of anti- and proarrhythmic processes. 
  • The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease). 
  • The classical versus the Cabrera presentation system for resting electrocardiography: Impact on recognition and understanding of clinically important electrocardiographic changes. 
  • The construction of an anatomically based model of the human ventricular conduction system. 
  • The current state of medical simulation in interventional cardiology: a clinical document from the Society for Cardiovascular Angiography and Intervention's (SCAI) Simulation Committee. 
  • The direct incorporation of perfusion defect information to define ischemia and infarction in a finite element model of the left ventricle. 
  • The effect of cellular discontinuities on the transient subthreshold response of a one-dimensional cardiac model. 
  • The effects of local ventricular pacing on recovery from regional myocardial ischemia. 
  • The four-electrode resistivity technique as applied to cardiac muscle. 
  • The genetics of the J wave patterns. 
  • The hemodynamics of thrombus formation in arteries. 
  • The impact of adjacent isotropic fluids on electrograms from anisotropic cardiac muscle. A modeling study. 
  • The myogenic response in isolated rat cerebrovascular arteries: smooth muscle cell model. 
  • The relationship between retinal vessel tortuosity, diameter, and transmural pressure. 
  • The restitution portrait: a new method for investigating rate-dependent restitution. 
  • The role of intrinsic and induced vulnerability in electrically induced cardiac arrhythmias. 
  • The role of spatial interactions in creating the dispersion of transmembrane potential by premature electric shocks. 
  • The role restitution in pacing induced spiral wave acceleration. 
  • The transport of LDL across the deformable arterial wall: the effect of endothelial cell turnover and intimal deformation under hypertension. 
  • The use of radionuclide angiography in the diagnosis of coronary artery disease--a logistic regression analysis. 
  • Theoretical simulation of oxygen transport to tumors by three-dimensional networks of microvessels. 
  • Therapeutic implications of biomarkers in chronic heart failure. 
  • Three-dimensional tumor perfusion reconstruction using fractal interpolation functions. 
  • Time-dependent predictors of primary cardiac arrest in patients with acute myocardial infarction. 
  • Tissue prolapse and stresses in stented coronary arteries: A computer model for multi-layer atherosclerotic plaque. 
  • To the editor: functional imaging(FI) combines imaging datasets and computational fluid dynamics to simulate cardiac flows. 
  • Tone-dependent waterfall behavior during venous pressure elevation in isolated canine hearts. 
  • Two-dimensional and Doppler-echocardiographic and cardiac catheterization correlates of survival in primary pulmonary hypertension. 
  • Ultrasonic characterization of the nonlinear properties of canine livers by measuring shear wave speed and axial strain with increasing portal venous pressure. 
  • Ultrasound-heated photoacoustic flowmetry. 
  • Understanding sex differences in long-term blood pressure regulation: insights from experimental studies and computational modeling. 
  • Unidirectional block in a computer model of partially coupled segments of cardiac Purkinje tissue. 
  • Use and associated risks of concomitant aspirin therapy with oral anticoagulation in patients with atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Registry. 
  • Use of an isolated heart model to test the utilization of substrates for inclusion in cardioplegic solutions. 
  • Use of computer simulation for determining endovascular skill levels in a carotid stenting model. 
  • Use of serum markers to measure acute myocardial infarct size: lessons of a nonlinear dynamical model. 
  • Validation of the Mayo clinic risk score for in-hospital mortality after percutaneous coronary interventions using the national cardiovascular data registry. 
  • Validation of three-dimensional conduction models using experimental mapping: are we getting closer? 
  • Validity of a risk-prediction tool for hospital mortality: the Global Registry of Acute Coronary Events. 
  • Value of serial troponin T measures for early and late risk stratification in patients with acute coronary syndromes. The GUSTO-IIa Investigators. 
  • Viscoelastic properties of the aortic valve interstitial cell. 
  • Viscous flow of cytoplasm and red cell membrane: membrane recovery and tether contraction. 
  • Vortex formation time is not an index of ventricular function. 
  • Vulnerability in an excitable medium: analytical and numerical studies of initiating unidirectional propagation. 
  • Wavelet formation in excitable cardiac tissue: the role of wavefront-obstacle interactions in initiating high-frequency fibrillatory-like arrhythmias. 
  • What happens when cardiac Na channel function is compromised? 2. Numerical studies of the vulnerable period in tissue altered by drugs. 
  • What happens when cardiac Na channels lose their function? 1--numerical studies of the vulnerable period in tissue expressing mutant channels. 
  • Why Is Infarct Expansion Such an Elusive Therapeutic Target? 
  • [An Experimental Set-Up for Navigated-Contrast-Agent and Radiation Sparing Endovascular Aortic Repair (Nav-CARS EVAR)]. 
  • β-Arrestin mediates the Frank-Starling mechanism of cardiac contractility. 
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  Keywords of People

  • Craciunescu, Oana, Professor of Radiation Oncology, Radiation Oncology
  • Henriquez, Craig S., Professor of Biomedical Engineering, Pratt School of Engineering
  • Johnson, G. Allan, Charles E. Putman University Distinguished Professor of Radiology, Physics
  • Malkin, Robert A., Professor of the Practice in the Department of Biomedical Engineering, Duke Science & Society
  • Milano, Carmelo Alessio, Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Neu, Wanda Krassowska, Professor Emeritus of Biomedical Engineering, Biomedical Engineering
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. Distinguished Professor, Medicine, Clinical Pharmacology
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery
  • Segars, William Paul, Associate Professor in Radiology, Radiology
  • Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • Turkington, Timothy Garvey, Associate Professor in Radiology, Radiology
  • Warner, David Samuel, Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology