Leukemia Virus, Murine

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  Subject Areas on Research

  • Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line. 
  • Biochemical and biological studies of mouse APOBEC3. 
  • CBF, Myb, and Ets binding sites are important for activity of the core I element of the murine retrovirus SL3-3 in T lymphocytes. 
  • CD4+Thy1- thymocytes with a Th-type 2 cytokine response. 
  • Characterization of the immune response to the major glycoprotein (gp71) of Friend leukemia virus. II. Response in C57BL/6 mice. 
  • Contained indirect viable-cell membrane immunofluorescence microassay for surface antigen analysis of cells infected with hazardous viruses. 
  • Cross-reacting antigens on L5178Y cells which serve as targets for cytotoxic T-lymphocyte lysis during establishment of the tumor dormant state. 
  • Development and characterization of an Fv-1-sensitive retrovirus-packaging system: single-hit titration kinetics observed in restrictive cells. 
  • Differential sensitivity of murine leukemia virus to APOBEC3-mediated inhibition is governed by virion exclusion. 
  • Effect of interferon on murine leukemia virus infection. II. Synthesis of viral components in exogenous infection. 
  • Enhanced type 1 immunity after secondary viral challenge in mice primed as neonates. 
  • Evidence that ecotropic murine leukemia virus contamination in TZM-bl cells does not affect the outcome of neutralizing antibody assays with human immunodeficiency virus type 1. 
  • Expression of murine leukemia virus structural antigens on the surface of chemically induced murine sarcomas. 
  • Further characterization of the oncornavirus inactivating factor in normal mouse serum. 
  • HIV-1 infection: fooling the gatekeeper. 
  • High-Frequency Illegitimate Strand Transfers of Nascent DNA Fragments During Reverse Transcription Result in Defective Retrovirus Genomes. 
  • Human APOBEC3 proteins can inhibit xenotropic murine leukemia virus-related virus infectivity. 
  • IFN-gamma production in response to neuropathogenic Cas-Br-M murine leukemia virus infection. 
  • Immunofluorescent analysis of expression of the RNA tumor virus major glycoprotein, gp71, on surfaces of virus-producing murine and other mammalian species cell lines. 
  • Immunofluorescent analysis of expression of the RNA tumor virus major glycoprotein, gp71, on the surfaces of normal murine cells. 
  • Immunogenic determinants of a neuropathogenic murine leukemia virus. 
  • Immunologic control of the ascites form of murine adenocarcinoma 755. II. Tumor immunity associated with a Friend--Moloney--Ra,scher-type virus. 
  • Importance of a c-Myb binding site for lymphomagenesis by the retrovirus SL3-3. 
  • Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector. 
  • In vivo antigenic modification of tumor cells. III. Metastatic thymic lymphoma specifically infected by thymotropic retrovirus. 
  • Inactivation of murine xenotropic oncornavirus by normal mouse sera is not immunoglobulin-mediated. 
  • Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers. 
  • Induction of cytotoxic T cell responses in newborn mice by DNA immunization. 
  • Induction of protective CTL responses in newborn mice by a murine retrovirus. 
  • Inhibition of lymphocyte proliferation by a synthetic peptide homologous to retroviral envelope proteins. 
  • Loss of tumorigenicity following in vitro MuLV infection is associated with induction of peritoneal natural killer cell activity. 
  • Morphologic and immunologic studies of human prostatic carcinoma. 
  • Morphological, chemical, and antigenic organization of mammalian C-type viruses. 
  • Murine in vitro antigenic modification of tumor cells: effect on susceptibility to natural cell-mediated cytotoxicity. 
  • Neisseria gonorrhoeae-induced human defensins 5 and 6 increase HIV infectivity: role in enhanced transmission. 
  • Neonate-primed CD8+ memory cells rival adult-primed memory cells in antigen-driven expansion and anti-viral protection. 
  • Oncogenic and immunogenic potential of cloned HIX virus in mice and cats. 
  • Production of a retroviral P15E-related chemotaxis inhibitor by IL-1-treated endothelial cells. A possible negative feedback in the regulation of the vascular response to monokines. 
  • Properties of mouse leukemia viruses. II. Isolation of viral components. 
  • Properties of mouse leukemia viruses. XIX. Effective antibody therapy of AKR leukemia occurs independently of virus neutralization and produces long-term changes in the virus status of the thymus. 
  • Properties of mouse leukemia viruses. XVII. Factors required for successful treatment of spontaneous AKR leukemia by antibodies against gp71. 
  • Pseudotyped viruses permit rapid detection of neutralizing antibodies in human and equine serum against Venezuelan equine encephalitis virus. 
  • Purification and serological characterization of the major envelope glycoprotein from AKR murine leukemia virus and its reactivity with autogenous immune sera from mice. 
  • Receptors for immunoglobulin and complement on mouse leukemias and lymphomas. 
  • Retroviral DNA integration: viral and cellular determinants of target-site selection. 
  • Role and mechanism of action of the APOBEC3 family of antiretroviral resistance factors. 
  • Role of antibodies to murine leukemia virus p15E transmembrane protein in immunotherapy against AKR leukemia: a model for studies in human acquired immunodeficiency syndrome. 
  • Specificity and distribution of the determinants of the major glycoprotein (gp71) of murine oncornaviruses as detected by an in vitro cytotoxicity assay. 
  • Structure and morphogenesis of type-C retroviruses. 
  • Suppression of leukaemia virus pathogenicity by polyoma virus enhancers. 
  • Synthesis of acyclothymidine triphosphate and alpha-P-boranotriphosphate and their substrate properties with retroviral reverse transcriptase. 
  • The coenrichment of stem cells, prothymocytes, and stromal elements with ecotropic retrovirus-producing cells from the bone marrow of leukemia-prone AKR mice. 
  • The effects of leukemosuppressive immunotherapy on bone marrow infectious cell centers in AKR mice. 
  • The perforin-dependent immunological synapse allows T-cell activation-dependent tumor targeting by MLV vector particles. 
  • Ultraviolet-light-inactivated Cas-Br-M murine leukemia virus induces a protective CD8+ cytotoxic T lymphocyte response in newborn mice. 
  • VSV-G pseudotyped, MuLV-based, semi-replication-competent retrovirus for cancer treatment. 
  • Visualization of retroviral replication in living cells reveals budding into multivesicular bodies. 
  • XVIII. Effective treatment of AKR leukemia with antibody to gp7 1 eliminates the neonatal burst of ecotropic AKR virus producing cells. 
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  Keywords of People

  • Cianciolo, George James, Associate Professor in Pathology, Pathology