Mucins

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  Subject Areas on Research

  • (90)Y-clivatuzumab tetraxetan with or without low-dose gemcitabine: A phase Ib study in patients with metastatic pancreatic cancer after two or more prior therapies. 
  • Airway mucus obstruction: mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia. 
  • An effective strategy for decontamination, ex vivo expansion, and storage of human fetal liver hematopoietic stem cells. 
  • Arachidonic acid stimulates mucin secretion in prairie dog gallbladder. 
  • Bile salts stimulate glycoprotein release by guinea pig gallbladder in vitro. 
  • CD62-PSGL-1 interactions regulate cytokine chemokine and apoptotic networks in cardiac allograft recipients. 
  • COPD: balancing oxidants and antioxidants. 
  • CT attenuation of unilocular pancreatic cystic lesions to differentiate pseudocysts from mucin-containing cysts. 
  • Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. 
  • Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia. 
  • Clear cell change in colonic tubular adenoma and corresponding colonic clear cell adenocarcinoma is associated with an altered mucin core protein profile. 
  • Coculture of mesenchymal stem cells and respiratory epithelial cells to engineer a human composite respiratory mucosa. 
  • Comparison of a novel assay for breast cancer mucin to CA15-3 and carcinoembryonic antigen. 
  • Cross-validation analysis of the prognostic significance of mucin expression in patients with resected non-small cell lung cancer treated with adjuvant chemotherapy: results from IALT, JBR.10 and ANITA. 
  • Diagnosis of diffuse malignant mesothelioma: experience of a US/Canadian Mesothelioma Panel. 
  • Differential production of high molecular weight sulfated glycoproteins in normal colonic mucosa, primary colon carcinoma, and metastases. 
  • Ectopic expression of mucins in colorectal cancer metastasis. 
  • Endocrine Mucin-Producing Sweat Gland Carcinoma of the Eyelid Associated With Mucinous Adenocarcinoma. 
  • Evaluation of expression based markers for the detection of breast cancer cells. 
  • Gallbladder glycoprotein secretion in mice with hemolytic anemia and pigment gallstones. 
  • Genetic Deletion of β-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Model. 
  • Goblet-cell mucinous epithelium lining the endometrium and endocervix: evidence of metastasis from an appendiceal primary tumor through the use of cytokeratin-7 and -20 immunostains. 
  • Human colonic sulfomucin identified by a specific monoclonal antibody. 
  • Human secretory immunoglobulin A may contribute to biofilm formation in the gut. 
  • Hydrocortisone inhibits mucin secretion from guinea pig gallbladder. 
  • Hypersecretion of mucin in response to inflammatory mediators by guinea pig tracheal epithelial cells in vitro is blocked by inhibition of nitric oxide synthase. 
  • IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling. 
  • Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects. 
  • Intraductal papillary mucinous neoplasm (IPMN) with extra-pancreatic mucin: a case series and review of the literature. 
  • Isolation and characterization of cDNA clones encoding pig gastric mucin. 
  • Lack of evidence for MHC-unrestricted (atypical) recognition of mucin by mucinous pancreatic tumour-reactive T-cells. 
  • MARCKS and HSP70 interactions regulate mucin secretion by human airway epithelial cells in vitro. 
  • MUC1 mucin expression as a marker of progression and metastasis of human colorectal carcinoma. 
  • Molecular composition of the node of Ranvier: identification of ankyrin-binding cell adhesion molecules neurofascin (mucin+/third FNIII domain-) and NrCAM at nodal axon segments. 
  • Monoclonal antibody against human colonic sulfomucin: immunochemical detection of its binding sites in colonic mucosa, colorectal primary carcinoma, and metastases. 
  • Mucin gene expression (MUC1, MUC2, and MUC5/5AC) in nasal epithelial cells of cystic fibrosis, allergic rhinitis, and normal individuals. 
  • Mucin gene expression in ovarian cancers. 
  • Mucin is produced by clara cells in the proximal airways of antigen-challenged mice. 
  • Mucins, mucus, and sputum. 
  • Mucoepidermoid carcinoma of the esophagus: a case report. 
  • Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma. 
  • Neutrophil elastase increases MUC4 expression in normal human bronchial epithelial cells. 
  • Neutrophil elastase increases MUC5AC mRNA and protein expression in respiratory epithelial cells. 
  • Neutrophil elastase induces MUC5AC gene expression in airway epithelium via a pathway involving reactive oxygen species. 
  • Neutrophil elastase induces MUC5AC messenger RNA expression by an oxidant-dependent mechanism. 
  • Neutrophil elastase induces mucus cell metaplasia in mouse lung. 
  • New member of the trefoil factor family of proteins is an alpha-macroglobulin protease inhibitor. 
  • Oxidant stress stimulates mucin secretion and PLC in airway epithelium via a nitric oxide-dependent mechanism. 
  • Pathologic response to preoperative chemotherapy in colorectal liver metastases: fibrosis, not necrosis, predicts outcome. 
  • Prognostic significance of mucin and p53 expression in stage IB non-small cell lung cancer: a laboratory companion study to CALGB 9633. 
  • Protein kinase C and Ca2+ activation of mucin secretion in airway goblet cells. 
  • Pseudopod-like basal cell processes in intestinal cholecystokinin cells. 
  • Quantitation of mucin mRNA in respiratory and intestinal epithelial cells. 
  • Reflectance confocal microscopy features of angioma serpiginosum. 
  • Regulation of MUC5AC expression by NAD(P)H:quinone oxidoreductase 1. 
  • Regulation of mucin genes in chronic inflammatory airway diseases. 
  • Respiratory carcinoma cell lines. MUC genes and glycoconjugates. 
  • Respiratory tract mucin genes and mucin glycoproteins in health and disease. 
  • Role of competition for nutrients in suppression of Clostridium difficile by the colonic microflora. 
  • Secretory IgA and mucin-mediated biofilm formation by environmental strains of Escherichia coli: role of type 1 pili. 
  • Sensitive and specific detection of the 4B5 antigen in bronchial lavage specimens from patients with primary bronchogenic carcinoma. 
  • Shigella dysenteriae modulates BMP pathway to induce mucin gene expression in vivo and in vitro. 
  • Sialyl-dimeric Lewis-X antigen expressed on mucin-like glycoproteins in colorectal cancer metastases. 
  • Soluble factor in normal tissues that stimulates high-molecular-weight sialoglycoprotein production by human colon carcinoma cells. 
  • Stevens-Johnson syndrome induced by the cross-reactivity between teicoplanin and vancomycin. 
  • Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice. 
  • Subcutaneous granuloma annulare: MR imaging features in six children and literature review. 
  • Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. 
  • Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal. 
  • The acceptor substrate specificity of porcine submaxillary UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase is dependent on the amino acid sequences adjacent to serine and threonine residues. 
  • Tumor necrosis factor-alpha (TNF-alpha) stimulates mucin secretion and gene expression in airway epithelium in vitro. 
  • Tumor necrosis factor-alpha stimulates mucin secretion and cyclic GMP production by guinea pig tracheal epithelial cells in vitro. 
  • Ultrastructure and function of the fractalkine mucin domain in CX(3)C chemokine domain presentation. 
  • Unique chromosomal rearrangement and mucin production in a novel salivary myoepithelial cell strain. 
  • Viscous fingering of HCl through gastric mucin. 
  • What does mucin have to do with lung disease? 
  • pH-dependent conformational change of gastric mucin leads to sol-gel transition. 
  • β2-Adrenoceptor agonists are required for development of the asthma phenotype in a murine model. 
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  Keywords of People

  • Erickson, Harold Paul, James B. Duke Distinguished Professor of Cell Biology, Cell Biology
  • Gunn, Michael Dee, Professor of Medicine, Immunology