Mucins

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  Subject Areas on Research

  • (90)Y-clivatuzumab tetraxetan with or without low-dose gemcitabine: A phase Ib study in patients with metastatic pancreatic cancer after two or more prior therapies. 
  • A MUC16 IgG Binding Activity Selects for a Restricted Subset of IgG Enriched for Certain Simian Immunodeficiency Virus Epitope Specificities. 
  • An effective strategy for decontamination, ex vivo expansion, and storage of human fetal liver hematopoietic stem cells. 
  • Arachidonic acid stimulates mucin secretion in prairie dog gallbladder. 
  • Bile salts stimulate glycoprotein release by guinea pig gallbladder in vitro. 
  • Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. 
  • Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia. 
  • Clear cell change in colonic tubular adenoma and corresponding colonic clear cell adenocarcinoma is associated with an altered mucin core protein profile. 
  • Comparison of a novel assay for breast cancer mucin to CA15-3 and carcinoembryonic antigen. 
  • Diagnosis of diffuse malignant mesothelioma: experience of a US/Canadian Mesothelioma Panel. 
  • Differential production of high molecular weight sulfated glycoproteins in normal colonic mucosa, primary colon carcinoma, and metastases. 
  • Ectopic expression of mucins in colorectal cancer metastasis. 
  • Endocrine Mucin-Producing Sweat Gland Carcinoma of the Eyelid Associated With Mucinous Adenocarcinoma. 
  • Evaluation of expression based markers for the detection of breast cancer cells. 
  • Gallbladder glycoprotein secretion in mice with hemolytic anemia and pigment gallstones. 
  • Genetic Deletion of β-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Model. 
  • Goblet-cell mucinous epithelium lining the endometrium and endocervix: evidence of metastasis from an appendiceal primary tumor through the use of cytokeratin-7 and -20 immunostains. 
  • Human colonic sulfomucin identified by a specific monoclonal antibody. 
  • Human conjunctival surface mucins: a quantitative study of normal and diseased (KCS) tissue. 
  • Human secretory immunoglobulin A may contribute to biofilm formation in the gut. 
  • Hydrocortisone inhibits mucin secretion from guinea pig gallbladder. 
  • Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects. 
  • Intestinal Sulfation Is Essential to Protect Against Colitis and Colonic Carcinogenesis. 
  • Intraductal papillary mucinous neoplasm (IPMN) with extra-pancreatic mucin: a case series and review of the literature. 
  • Isolation and characterization of cDNA clones encoding pig gastric mucin. 
  • Lack of evidence for MHC-unrestricted (atypical) recognition of mucin by mucinous pancreatic tumour-reactive T-cells. 
  • MUC1 mucin expression as a marker of progression and metastasis of human colorectal carcinoma. 
  • Molecular composition of the node of Ranvier: identification of ankyrin-binding cell adhesion molecules neurofascin (mucin+/third FNIII domain-) and NrCAM at nodal axon segments. 
  • Monoclonal antibody against human colonic sulfomucin: immunochemical detection of its binding sites in colonic mucosa, colorectal primary carcinoma, and metastases. 
  • Mucoepidermoid carcinoma of the esophagus: a case report. 
  • Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma. 
  • New member of the trefoil factor family of proteins is an alpha-macroglobulin protease inhibitor. 
  • Pathologic response to preoperative chemotherapy in colorectal liver metastases: fibrosis, not necrosis, predicts outcome. 
  • Prognostic significance of mucin and p53 expression in stage IB non-small cell lung cancer: a laboratory companion study to CALGB 9633. 
  • Protein kinase C and Ca2+ activation of mucin secretion in airway goblet cells. 
  • Pseudopod-like basal cell processes in intestinal cholecystokinin cells. 
  • Reflectance confocal microscopy features of angioma serpiginosum. 
  • Role of competition for nutrients in suppression of Clostridium difficile by the colonic microflora. 
  • Secretory IgA and mucin-mediated biofilm formation by environmental strains of Escherichia coli: role of type 1 pili. 
  • Sialyl-dimeric Lewis-X antigen expressed on mucin-like glycoproteins in colorectal cancer metastases. 
  • Soluble factor in normal tissues that stimulates high-molecular-weight sialoglycoprotein production by human colon carcinoma cells. 
  • Stevens-Johnson syndrome induced by the cross-reactivity between teicoplanin and vancomycin. 
  • Subcutaneous granuloma annulare: MR imaging features in six children and literature review. 
  • Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. 
  • The acceptor substrate specificity of porcine submaxillary UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase is dependent on the amino acid sequences adjacent to serine and threonine residues. 
  • The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infections. 
  • Ultrastructure and function of the fractalkine mucin domain in CX(3)C chemokine domain presentation. 
  • Unique chromosomal rearrangement and mucin production in a novel salivary myoepithelial cell strain. 
  • Viscous fingering of HCl through gastric mucin. 
  • pH-dependent conformational change of gastric mucin leads to sol-gel transition. 
  • β2-Adrenoceptor agonists are required for development of the asthma phenotype in a murine model. 
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  Keywords of People

  • Erickson, Harold Paul, James B. Duke Distinguished Professor of Cell Biology, Cell Biology
  • Gunn, Michael Dee, Professor of Medicine, Immunology