Mucormycosis

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  Subject Areas on Research

  • A Novel Resistance Pathway for Calcineurin Inhibitors in the Human-Pathogenic Mucorales Mucor circinelloides. 
  • A non-canonical RNA degradation pathway suppresses RNAi-dependent epimutations in the human fungal pathogen Mucor circinelloides. 
  • A non-canonical RNAi pathway controls virulence and genome stability in Mucorales. 
  • Adjunctive hyperbaric oxygen for treatment of rhinocerebral mucormycosis. 
  • An atypical case of fatal zygomycosis: simultaneous cutaneous and laryngeal infection in a patient with a non-neutropenic solid prostatic tumor. 
  • Analysis of a food-borne fungal pathogen outbreak: virulence and genome of a Mucor circinelloides isolate from yogurt. 
  • Antifungal drug resistance evoked via RNAi-dependent epimutations. 
  • Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides. 
  • Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides. 
  • Changing Epidemiology of Invasive Mold Infections in Patients Receiving Azole Prophylaxis. 
  • Components of a new gene family of ferroxidases involved in virulence are functionally specialized in fungal dimorphism. 
  • Construction of a Recyclable Genetic Marker and Serial Gene Deletions in the Human Pathogenic Mucorales Mucor circinelloides. 
  • Control of morphology and virulence by ADP-ribosylation factors (Arf) in Mucor circinelloides. 
  • Deferoxamine treatment as a risk factor for zygomycete infection. 
  • Disseminated zygomycosis: report of four cases and review. 
  • Drug-Resistant Epimutants Exhibit Organ-Specific Stability and Induction during Murine Infections Caused by the Human Fungal Pathogen Mucor circinelloides. 
  • ECMM/ISHAM recommendations for clinical management of COVID-19 associated mucormycosis in low- and middle-income countries. 
  • Fatal Apophysomyces elegans infection transmitted by deceased donor renal allografts. 
  • Gastrointestinal microbiota alteration induced by Mucor circinelloides in a murine model. 
  • Guidance on Imaging for Invasive Pulmonary Aspergillosis and Mucormycosis: From the Imaging Working Group for the Revision and Update of the Consensus Definitions of Fungal Disease from the EORTC/MSGERC. 
  • Heterothallic mating in Mucor irregularis and first isolate of the species outside of Asia. 
  • Heterotrimeric G-alpha subunits Gpa11 and Gpa12 define a transduction pathway that control spore size and virulence in Mucor circinelloides. 
  • Hostile takeover: fungal protein promotes host cell invasion. 
  • Images in clinical medicine. Mucormycosis of the hand and forearm. 
  • Isavuconazole treatment for mucormycosis: a single-arm open-label trial and case-control analysis. 
  • Isavuconazole treatment for rare fungal diseases and for invasive aspergillosis in patients with renal impairment: Challenges and lessons of the VITAL trial. 
  • Let's talk about sex characteristics-As a risk factor for invasive fungal diseases. 
  • Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs. 
  • Mucor circinelloides Thrives inside the Phagosome through an Atf-Mediated Germination Pathway. 
  • Mucor circinelloides: Growth, Maintenance, and Genetic Manipulation. 
  • Mucormycosis Rhinosinusitis at Diagnosis of Acute Lymphoblastic Leukemia: Diagnostics and Management Challenges in a Low-Middle-income Country. 
  • Mucormycosis after open fracture injury. 
  • Mucormycosis. 
  • Mucormycosis: time to address this deadly fungal infection. 
  • Opportunistic fungal pneumonia. 
  • Outbreak of Invasive Wound Mucormycosis in a Burn Unit Due to Multiple Strains of Mucor circinelloides f. circinelloides Resolved by Whole-Genome Sequencing. 
  • Photo Quiz: A 9-Year-Old Girl with Eye Swelling and Drainage. 
  • Pulmonary mucormycosis: radiologic findings in 32 cases. 
  • RNAi-Based Functional Genomics Identifies New Virulence Determinants in Mucormycosis. 
  • Rhizopus presenting as an endobronchial obstruction following bone marrow transplant. 
  • Risk factors for mortality in patients with mucormycosis. 
  • Scedosporium prolificans osteomyelitis in an immunocompetent child treated with voriconazole and caspofungin, as well as locally applied polyhexamethylene biguanide. 
  • Spotlight on isavuconazole in the treatment of invasive aspergillosis and mucormycosis: design, development, and place in therapy. 
  • The Deferasirox-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) study: a randomized, double-blinded, placebo-controlled trial. 
  • The current treatment landscape: other fungal diseases (cryptococcosis, fusariosis and mucormycosis). 
  • The emergence of COVID-19 associated mucormycosis: a review of cases from 18 countries. 
  • The use of genome sequencing to investigate an outbreak of hospital-acquired mucormycosis in transplant patients. 
  • Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds. 
  • Transformation and CRISPR-Cas9-mediated homologous recombination in the fungus Rhizopus microsporus . 
  • Understanding Mucor circinelloides pathogenesis by comparative genomics and phenotypical studies. 
  • Use of Multimodality Imaging in Diagnosing Invasive Fungal Diseases of the Heart. 
  • Use of external ventriculostomy and intrathecal anti-fungal treatment in cerebral mucormycotic abscess. 
  • Widely disseminated Cunninghamella mucormycosis in an adult renal transplant patient: case report and review of the literature. 
  • Zygomycosis caused by Cunninghamella bertholletiae: mycologic aspects. 
  • Zygomycosis of the basal ganglia in intravenous drug users. 
  • Zygomycosis: the re-emerging fungal infection. 
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  Keywords of People

  • Moon, Richard Edward, Professor of Anesthesiology, Medicine, Pulmonary, Allergy, and Critical Care Medicine
  • Patz Jr., Edward F., James and Alice Chen Distinguished Professor of Radiology, Pathology