Mucous Membrane

• 

  Subject Areas on Research

  • A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections. 
  • A phase I/II trial of twice daily irradiation and concurrent chemotherapy for locally advanced squamous cell carcinoma of the head and neck. 
  • Ablative therapies for Barrett's esophagus. 
  • Agrin in the Muscularis Mucosa Serves as a Biomarker Distinguishing Hyperplastic Polyps from Sessile Serrated Lesions. 
  • Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring. 
  • Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques. 
  • Analysis of vaginal microbicide film hydration kinetics by quantitative imaging refractometry. 
  • Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia. 
  • B cell responses to HIV-1 infection and vaccination: pathways to preventing infection. 
  • Bacterial penetration of the mucosal barrier by targeting lipid rafts. 
  • Broadly Neutralizing Antibodies Display Potential for Prevention of HIV-1 Infection of Mucosal Tissue Superior to That of Nonneutralizing Antibodies. 
  • CD161 contributes to prenatal immune suppression of IFNγ-producing PLZF+ T cells. 
  • CD169-dependent cell-associated HIV-1 transmission: a driver of virus dissemination. 
  • CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques. 
  • CT mucosal window settings: a novel approach to evaluating early T-stage head and neck carcinoma. 
  • Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types. 
  • Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study. 
  • Comparison of systemic and mucosal delivery of 2 canarypox virus vaccines expressing either HIV-1 genes or the gene for rabies virus G protein. 
  • Comparison of systemic and mucosal immunization with helper-dependent adenoviruses for vaccination against mucosal challenge with SHIV. 
  • Comparison of systemic and mucosal vaccination: impact on intravenous and rectal SIV challenge. 
  • Compartmental transport model of microbicide delivery by an intravaginal ring. 
  • Conference on advances in AIDS vaccine development--1993. Summary: correlates of HIV Immunity Working Group. 
  • DNA-MVA-protein vaccination of rhesus macaques induces HIV-specific immunity in mucosal-associated lymph nodes and functional antibodies. 
  • Deducing Mucosal Pharmacokinetics and Pharmacodynamics of the Anti-HIV Molecule Tenofovir from Measurements in Blood. 
  • Deficiency of Mucosal-Associated Invariant T Cells in TCRJα18 Germline Knockout Mice. 
  • Depth of Muscularis Propria Invasion Does Not Prognosticate Survival in T2 Esophageal Adenocarcinoma. 
  • Dermatitis herpetiformis and the mucosal immune response. 
  • Double blind randomized trial of sucralfate vs placebo during radical radiotherapy for head and neck cancers. 
  • Dry powder vaccines for mucosal administration: critical factors in manufacture and delivery. 
  • Effect of vasopressin and serosal hypertonicity on toad urinary bladder. 
  • Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif. 
  • Expanding opportunities to engineer mucosal vaccination with biomaterials. 
  • Expression of CD1d and ligand-induced cytokine production are tissue specific in mucosal epithelia of the human lower reproductive tract. 
  • Functional Perturbation of Mucosal Group 3 Innate Lymphoid and Natural Killer Cells in Simian-Human Immunodeficiency Virus/Simian Immunodeficiency Virus-Infected Infant Rhesus Macaques. 
  • HIV-1-negative female sex workers sustain high cervical IFNɛ, low immune activation, and low expression of HIV-1-required host genes. 
  • Hailey-Hailey disease with acantholysis of the oral and oesophagogastric mucosa. 
  • Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues. 
  • Helper Th1 and Th2 cell responses following mucosal or systemic immunization with cholera toxin. 
  • High-resolution cross-sectional imaging of the gastrointestinal tract using optical coherence tomography: preliminary results. 
  • Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. 
  • Incidence, Risk Factors, and Outcomes of Patients Who Develop Mucosal Barrier Injury-Laboratory Confirmed Bloodstream Infections in the First 100 Days After Allogeneic Hematopoietic Stem Cell Transplant. 
  • Influence of age on the pharmacokinetics and pharmacodynamics of oral transmucosal fentanyl citrate. 
  • Intranasal immunization is superior to vaginal, gastric, or rectal immunization for the induction of systemic and mucosal anti-HIV antibody responses. 
  • Intravascular food reward. 
  • Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium. 
  • Label-free analysis of tenofovir delivery to vaginal tissue using co-registered confocal Raman spectroscopy and optical coherence tomography. 
  • Low plasma concentrations of retinol and alpha-tocopherol in hematopoietic stem cell transplant recipients: the effect of mucositis and the risk of infection. 
  • Malignant melanoma of the mucous membranes: a review of 119 cases. 
  • Marrow transplantation for Fanconi anemia with or without leukemic transformation: an update of the Seattle experience. 
  • Middle ear packing: comparison of materials in an animal model of mucosal trauma. 
  • Morphologic features of 115 lymphomas of the orbit and ocular adnexa categorized according to the World Health Organization classification: are marginal zone lymphomas in the orbit mucosa-associated lymphoid tissue-type lymphomas? 
  • Mucosal and systemic anti-HIV responses in rhesus macaques following combinations of intranasal and parenteral immunizations. 
  • Mucosal candidiasis elicits NF-κB activation, proinflammatory gene expression and localized neutrophilia in zebrafish. 
  • Mucosal co-infections and HIV-1 transmission and pathogenesis. 
  • Mucosal human defensins 5 and 6 antagonize the anti-HIV activity of candidate polyanion microbicides. 
  • Mucosal melanoma of the female genitalia: a clinicopathologic study of forty-three cases at Duke University Medical Center. 
  • Mucosal melanoma of the head and neck. 
  • Mucosal melanoma. 
  • Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits. 
  • Mucosal vaccine development for botulinum intoxication. 
  • Mucosal vaccine targeting improves onset of mucosal and systemic immunity to botulinum neurotoxin A. 
  • Multicompartmental pharmacokinetic model of tenofovir delivery by a vaginal gel. 
  • Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection. 
  • Non-replicating mucosal and systemic vaccines: quantitative and qualitative differences in the Ag-specific CD8(+) T cell population in different tissues. 
  • Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node. 
  • Novel intranasal pertussis vaccine based on bacterium-like particles as a mucosal adjuvant. 
  • Ocular mucosal CD11b+ and CD103+ mouse dendritic cells under normal conditions and in allergic immune responses. 
  • Oral Coadministration of an Intramuscular DNA/Modified Vaccinia Ankara Vaccine for Simian Immunodeficiency Virus Is Associated with Better Control of Infection in Orally Exposed Infant Macaques. 
  • Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: implications for use in vaccine studies. 
  • Personalized Radiation Attenuating Materials for Gastrointestinal Mucosal Protection. 
  • Phenamil: an irreversible inhibitor of sodium channels in the toad urinary bladder. 
  • Photodynamic therapy of Barrett's esophagus: ablation of Barrett's mucosa and reduction in p53 protein expression after treatment. 
  • Porcine reproductive and respiratory syndrome virus induces pronounced immune modulatory responses at mucosal tissues in the parental vaccine strain VR2332 infected pigs. 
  • Prenatal exposure to stilbestrol. A prospective comparison of exposed female offspring with unexposed controls. 
  • Protein kinase C and Ca2+ activation of mucin secretion in airway goblet cells. 
  • Radioprotective effects of amifostine on acute and chronic esophageal injury in rodents. 
  • Recombinant Mycobacterium bovis bacillus Calmette-Guerin elicits human immunodeficiency virus type 1 envelope-specific T lymphocytes at mucosal sites. 
  • Rectal tissue and vaginal tissue from intravenous VRC01 recipients show protection against ex vivo HIV-1 challenge. 
  • Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques. 
  • Role of murine intestinal interleukin-1 receptor 1-expressing lymphoid tissue inducer-like cells in Salmonella infection. 
  • Safety and immunogenicity of an HIV-1 recombinant canarypox vaccine in newborns and infants of HIV-1-infected women. 
  • Submucosal glands are the predominant site of CFTR expression in the human bronchus. 
  • Swine influenza H1N1 virus induces acute inflammatory immune responses in pig lungs: a potential animal model for human H1N1 influenza virus. 
  • Systemic administration of an HIV-1 broadly neutralizing dimeric IgA yields mucosal secretory IgA and virus neutralization. 
  • Systemic and mucosal mobilization of granulocyte subsets during lentiviral infection. 
  • T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers. 
  • The Duke AFM Program. Intensive induction chemotherapy for metastatic breast cancer. 
  • The Presence and Anti-HIV-1 Function of Tenascin C in Breast Milk and Genital Fluids. 
  • The Roles of T cells in Bladder Pathologies. 
  • The common mucosal immune system: from basic principles to enteric vaccines with relevance for the female reproductive tract. 
  • The effect of cocaine on sperm motility characteristics and bovine cervical mucus penetration. 
  • The efficacy of anti-PD-1 agents in acral and mucosal melanoma. 
  • The immune response to HIV: implications for vaccine development. 
  • The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk. 
  • The pathogenesis of dermatitis herpetiformis. 
  • Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7. 
  • Up-Regulation of PARP1 Expression Significantly Correlated with Poor Survival in Mucosal Melanomas. 
  • Ureteral mullerianosis. 
  • Vaccination with Live Attenuated Simian Immunodeficiency Virus (SIV) Protects from Mucosal, but Not Necessarily Intravenous, Challenge with a Minimally Heterologous SIV. 
  • Vaccine induction of antibodies and tissue-resident CD8+ T cells enhances protection against mucosal SHIV-infection in young macaques. 
  • Vaccine with bacterium-like particles displaying HIV-1 gp120 trimer elicits specific mucosal responses and neutralizing antibodies in rhesus macaques. 
  • Vaginal deployment and tenofovir delivery by microbicide gels. 
  • Vaginal epithelial changes in young women enrolled in the National Cooperative Diethylstilbestrol Adenosis (DESAD) project. 
  • Zinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge. 
  • [Current perspectives of orthogonal polarization spectral imaging in plastic surgery]. 
  • mTOR is critical for intestinal T-cell homeostasis and resistance to Citrobacter rodentium. 
• 

  Keywords of People

  • Cohen, Seth Morris, Professor of Head and Neck Surgery & Communication Sciences, Head and Neck Surgery & Communication Sciences
  • Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology
  • Katz, David F., Nello L. Teer, Jr. Distinguished Professor of Biomedical Engineering, in the Edmund T. Pratt, Jr. School of Engineering, Biomedical Engineering
  • Staats, Herman Ford, Professor of Pathology, Integrative Immunobiology
  • Wax, Adam P., Professor of Biomedical Engineering, Biomedical Engineering
  • Woodward, Julie Ann, Professor of Ophthalmology, Dermatology