Muramidase

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  Subject Areas on Research

  • A threshold for central T cell tolerance to an inducible serum protein 
  • Adjuvant-free in vivo targeting. Antigen delivery by alpha 2-macroglobulin enhances antibody formation. 
  • Are metaplasias in colorectal adenomas truly metaplasias? 
  • CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. 
  • CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells. 
  • Chemoattractant receptor functions in human polymorphonuclear leukocytes are divergently altered by membrane fluidizers. 
  • Comparison of in vitro and in vivo differentiation of myeloblastic leukemia of the RFM/Un mouse. 
  • Cutting edge: hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation. 
  • Degradation of 14C-labeled streptococcal cell walls by egg white lysozyme and lysosomal enzymes. 
  • Dependence of germinal center B cells on expression of CD21/CD35 for survival. 
  • Detection and characterization of xenon-binding sites in proteins by 129Xe NMR spectroscopy. 
  • Development of specific receptors for N-formylated chemotactic peptides in a human monocyte cell line stimulated with lymphokines. 
  • Diacylglycerol kinase ζ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responses. 
  • Different dimerization activities of alpha and beta thyroid hormone receptor isoforms. 
  • Effects of the lpr mutation on elimination and inactivation of self-reactive B cells. 
  • Enzyme dehydration using Microglassification™ preserves the protein's structure and function. 
  • Exploring steric constraints on protein mutations using MAGE/PROBE. 
  • Fretting about FRET: correlation between kappa and R. 
  • Heparin modifies the immunogenicity of positively charged proteins. 
  • Human neutrophil dysfunction with giant granules and defective activation of the respiratory burst. 
  • Human splenic sinusoidal lining cells express antigens associated with monocytes, macrophages, endothelial cells, and T lymphocytes. 
  • Hydration potential of lysozyme: protein dehydration using a single microparticle technique. 
  • In vitro synthesis of phi-X-174 single-stranded DNA. 
  • Integrating statistical pair potentials into protein complex prediction. 
  • Kinetics of nonproteolytic incorporation of a protein ligand into thermally activated alpha 2-macroglobulin: evidence for a novel nascent state. 
  • Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4. 
  • Multilayer adsorption of lysozyme on a hydrophobic substrate. 
  • Nonproteolytic incorporation of protein ligands into human alpha 2-macroglobulin: implications for the binding mechanism of alpha 2-macroglobulin. 
  • Oral immunogenicity of the plant proteinase bromelain. 
  • Protein amyloidose misfolding: mechanisms, detection, and pathological implications. 
  • Protein dynamic studies move to a new time slot. 
  • Receptor-mediated antigen delivery into macrophages. Complexing antigen to alpha 2-macroglobulin enhances presentation to T cells. 
  • Regulatory mechanisms of a chemoattractant receptor on human polymorphonuclear leukocytes. 
  • Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells. 
  • Role of a guanine nucleotide regulatory protein in the activation of phospholipase C by different chemoattractants. 
  • SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa. 
  • Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. 
  • Temperature-sensitive hydrogels with SiO2-Au nanoshells for controlled drug delivery. 
  • Temporal control of self-organized pattern formation without morphogen gradients in bacteria. 
  • The nature of the intraperitoneal exudate associated with infertility: peritoneal fluid and serum lysozyme activity. 
  • Thermodynamic analysis of protein folding and stability using a tryptophan modification protocol. 
  • Transcription Factor RUNX1 Regulates Platelet PCTP (Phosphatidylcholine Transfer Protein): Implications for Cardiovascular Events: Differential Effects of RUNX1 Variants. 
  • Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers. 
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  Keywords of People

  • Gunn, Michael Dee, Professor of Medicine, Integrative Immunobiology