N-Formylmethionine
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Subject Areas on Research
- Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms.
- Alterations of new methylated phospholipid synthesis in the plasma membranes of macrophages exposed to chemoattractants.
- Amphotericin B alters the affinity and functional activity of the oligopeptide chemotactic factor receptor on human polymorphonuclear leukocytes.
- Chemoattractant receptor affinity reflects its ability to transduce different biological responses.
- Chemoattractant receptor functions in human polymorphonuclear leukocytes are divergently altered by membrane fluidizers.
- Chemotactically responsive and nonresposive forms of a continuous human monocyte cell line.
- Cyclic nucleotides regulate the morphologic alterations required for chemotaxis in monocytes.
- Demonstration of a chemotactic factor receptor on macrophages.
- Development of specific receptors for N-formylated chemotactic peptides in a human monocyte cell line stimulated with lymphokines.
- Guanine nucleotides modulate the binding affinity of the oligopeptide chemoattractant receptor on human polymorphonuclear leukocytes.
- Hormonal activation of adenylate cyclase in macrophage membranes is regulated by guanine nucleotides.
- Inhibitors of monocyte responses to chemotaxins are associated with human neoplasms.
- Polymorphonuclear leukocyte function in psoriasis: chemotaxis, chemokinesis, beta-adrenergic receptors, and proteolytic enzymes of polymorphonuclear leukocytes in the peripheral blood from psoriatic patients.