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Subject Areas on Research
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A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect.
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A fixative for use in muscle histochemistry.
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A metabolomic endotype of bioenergetic dysfunction predicts mortality in critically ill patients with acute respiratory failure.
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A new era for electron bifurcation.
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Abscisic acid activation of plasma membrane Ca(2+) channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in abi1-1 and abi2-1 protein phosphatase 2C mutants.
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Adenine nucleotides of ischemic intestine do not reflect injury.
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Affinity chromatography of beta-hydroxybutyrate dehydrogenase on Nad and hydrophobic chain derivatives of sepharose.
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Age-related metabolic fatigue during low glucose conditions in rat hippocampus.
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Agonist-promoted coupling of the beta-adrenergic receptor with the guanine nucleotide regulatory protein of the adenylate cyclase system.
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Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival.
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Assay of G-protein beta gamma-subunit complex by catalytic support of ADP-ribosylation of Go alpha.
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Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway.
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CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.
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Cerebral cortical microfluorometry at isosbestic wavelengths for correction of vascular artifact.
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Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice.
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Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.
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Deoxyribonucleic acid ligase. A steady state kinetic analysis of the reaction catalyzed by the enzyme from Escherichia coli.
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Deoxyribonucleic acid ligase. Isolation and physical characterization of the homogeneous enzyme from Escherichia coli.
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Detection of necrosis by release of lactate dehydrogenase activity.
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Effect of conformation on the binding of flavins to flavoenzymes.
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Effects of continuous-wave, pulsed, and sinusoidal-amplitude-modulated microwaves on brain energy metabolism.
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Effects of potassium on oxidative metabolism and seizures.
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Effects of relative hypoglycemia on LTP and NADH imaging in rat hippocampal slices.
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Elementary steps in the reaction mechanism of pyruvate dehydrogenase multienzyme complex from Escherichia coli: kinetics of flavin reduction.
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Enzyme/crystallins and extremely high pyridine nucleotide levels in the eye lens.
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Epimerization of an intermediary metabolite of norethynodrel by a 3 beta-hydroxy-delta 5(10)-steroid epimerase.
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Estradiol replacement enhances cocaine-stimulated locomotion in female C57BL/6 mice through estrogen receptor alpha.
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Exploiting metabolic differences in glioma therapy.
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Extremely high levels of NADPH in guinea pig lens: correlation with zeta-crystallin concentration.
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Fluorometric monitoring of NADH levels in cerebral cortex: preliminary observations in human epilepsy.
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Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.
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Hepatic sulfite oxidase. Congruency in mitochondria of prosthetic groups and activity.
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Hitting Gliomas When They Are Down: Exploiting IDH-Mutant Metabolic Vulnerabilities.
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Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique.
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Identification of key amino acids responsible for the substantially higher affinities of human type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD1) for substrates, coenzymes, and inhibitors relative to human 3beta-HSD2.
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Inhibiting glycolysis to reduce seizures: how it might work.
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Interaction between tissue oxygen tension and NADH imaging during synaptic stimulation and hypoxia in rat hippocampal slices.
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Interaction of reduced nicotinamide adenine dinucleotide with beef heart s-malate dehydrogenase.
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Interactions of nicotinamide adenine dinucleotides with varied states and forms of hemoglobin.
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Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH.
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Isomeric N-alkylpyridylporphyrins and their Zn(II) complexes: inactive as SOD mimics but powerful photosensitizers.
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Kinetics of allosteric enzymes.
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Mechanism of nicotinamide-adenine dinucleotide binding to rabbit muscle glyceraldehyde 3-phosphate dehydrogenase.
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Metabolic Regulation by Lysine Malonylation, Succinylation, and Glutarylation.
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Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease.
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Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio.
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Metabolic responses differentiate between interictal, ictal and persistent epileptiform activity in intact, immature hippocampus in vitro.
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Methotrexate-induced alterations in beta-oxidation correlate with cognitive abilities in children with acute lymphoblastic leukemia.
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Microwave effects on energy metabolism of rat brain.
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Mitochondrial NADH as the bellwether of tissue O2 delivery.
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Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues.
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Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands.
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Mitochondrial sirtuins.
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Modification of Escherichia coli DNA ligase by cleavage with trypsin.
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Molecular basis of the biological function of molybdenum. Molybdenum-free xanthine oxidase from livers of tungsten-treated rats.
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Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas.
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NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling.
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NAD+ modulates p53 DNA binding specificity and function.
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NADH fluorescence and [K+]o changes during hippocampal electrical stimulation.
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NADH fluorescence, [K+]0 and oxygen consumption in cat cerebral cortex during direct cortical stimulation.
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NADH hyperoxidation correlates with enhanced susceptibility of aged rats to hypoxia.
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NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding.
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Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities.
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Nicotinamide pre-treatment ameliorates NAD(H) hyperoxidation and improves neuronal function after severe hypoxia.
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Nonequivalence of the flavin adenine dinucleotide moieties of chicken liver xanthine dehydrogenase.
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On the occurrence of cytochrome P-450 and aryl hydrocarbon hydroxylase activity in rat brain.
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Oxidative metabolism during recurrent seizures in the penicillin treated hippocampus.
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Oxygen sufficiency in working rabbit papillary muscle at 35 degrees C.
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Peroxynitrite formation in nitric oxide-exposed submitochondrial particles: detection, oxidative damage and catalytic removal by Mn-porphyrins.
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Protection of mitochondrial function during ischemia by potassium cardioplegia: correlation with ischemic contracture.
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Purification and properties of chicken liver xanthine dehydrogenase.
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Purification and properties of the NAD+-dependent (type D) and O2-dependent (type O) forms of rat liver xanthine dehydrogenase.
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Pyruvate incubation enhances glycogen stores and sustains neuronal function during subsequent glucose deprivation.
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Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. 3. The Escherichia coli hemoflavoprotein: catalytic parameters and the sequence of electron flow.
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Relaxation spectrometry of biological systems.
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Reply: To PMID 22653543.
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Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties.
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Role of NAD+
and mitochondrial sirtuins in cardiac and renal diseases.
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Role of aspartic acid 38 in the cofactor specificity of Drosophila alcohol dehydrogenase.
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S-Adenosylhomocysteine hydrolase from human placenta. Affinity purification and characterization.
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SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism.
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STRUCTURE AND FUNCTION OF IRON-FLAVOPROTEINS.
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Simultaneous monitoring of tissue PO2 and NADH fluorescence during synaptic stimulation and spreading depression reveals a transient dissociation between oxygen utilization and mitochondrial redox state in rat hippocampal slices.
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Single dose of glutamine enhances myocardial tissue metabolism, glutathione content, and improves myocardial function after ischemia-reperfusion injury.
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Sorbitol dehydrogenase of rat testis: changes of activity during development, after hypophysectomy and following gonadotrophic hormone administration.
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Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex.
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Structure determination of selenomethionyl S-adenosylhomocysteine hydrolase using data at a single wavelength.
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Studies on the dissociation of flavin adenine dinucleotide from metalloflavoproteins.
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Temporal sequence and spatial distribution of early events of fertilization in single sea urchin eggs.
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The Warburg Effect: How Does it Benefit Cancer Cells?
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The design and operation of a dual-beal long-focal-length fluorometer for monitoring the oxidative metabolism in vivo.
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The differential effects of 200, 591, and 2,450 MHz radiation on rat brain energy metabolism.
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The effect of detergents on the reduction of tetrazolium salts.
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The effects of hyperthermia and hyperthermia plus microwaves on rat brain energy metabolism.
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The mechanism of conversion of rat liver xanthine dehydrogenase from an NAD+-dependent form (type D) to an O2-dependent form (type O).
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The nicotinamide adenine dinucleotides as allosteric effectors of human hemoglobin.
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Thermodynamic analysis of protein-ligand interactions in complex biological mixtures using a shotgun proteomics approach.
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Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo.
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Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
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Using genetically encoded fluorescent biosensors to interrogate ovarian cancer metabolism.
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Keywords of People