NADH, NADPH Oxidoreductases
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Subject Areas on Research
- A critical role for chloride channel-3 (CIC-3) in smooth muscle cell activation and neointima formation.
- A rapid micromethod for determination of FMN and FAD in mixtures.
- A television fluorometer for monitoring oxidative metabolism in intact tissue.
- Activation of NADPH oxidase 1 increases intracellular calcium and migration of smooth muscle cells.
- Activation of the respiratory burst enzyme from human neutrophils in a cell-free system. Evidence for a soluble cofactor.
- Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms.
- An oxidized extracellular oxidation-reduction state increases Nox1 expression and proliferation in vascular smooth muscle cells via epidermal growth factor receptor activation.
- Bacterial flavohemoglobin: a molecular tool to probe mammalian nitric oxide biology.
- Ca(2+)/calmodulin regulates Kvβ1.1-mediated inactivation of voltage-gated K(+) channels.
- Characterisation of PduS, the pdu metabolosome corrin reductase, and evidence of substructural organisation within the bacterial microcompartment.
- Cytochrome P-450- and glutathione-associated enzyme activities in freshly isolated enriched lung cell fractions from beta-naphthoflavone-treated male F344 rats.
- Effect of intratracheally administered DDT and endosulfan on pulmonary and hepatic respiratory cytochromes.
- Engineered modular recombinant transporters: application of new platform for targeted radiotherapeutic agents to alpha-particle emitting 211 At.
- Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock.
- GW112, a novel antiapoptotic protein that promotes tumor growth.
- Gene up-regulation in heart during mammalian hibernation.
- Granulocyte-macrophage colony-stimulating factor primes neutrophils by activating a pertussis toxin-sensitive G protein not associated with phosphatidylinositol turnover.
- H(2)O(2)-induced O(2) production by a non-phagocytic NAD(P)H oxidase causes oxidant injury.
- Hypothesis: iron chelation plays a vital role in neutrophilic inflammation.
- Identification of the iron-sulfur center of spinach ferredoxin-nitrite reductase as a tetranuclear center, and preliminary EPR studies of mechanism.
- Increased expression of Nox1 in neointimal smooth muscle cells promotes activation of matrix metalloproteinase-9.
- Magnetization of the sulfite and nitrite complexes of oxidized sulfite and nitrite reductases: EPR silent spin S = 1/2 states.
- Mechanisms of regulating the respiratory burst in leukocytes.
- Microglial oxyradical production: causes and consequences.
- NADPH-dependent oxygen reductase activity in pulmonary macrophages.
- Nox1 NADPH oxidase is necessary for late but not early myocardial ischaemic preconditioning.
- Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration.
- Nox4 NADPH oxidase contributes to smooth muscle cell phenotypes associated with unstable atherosclerotic plaques.
- Oxidative stress in human abdominal aortic aneurysms: a potential mediator of aneurysmal remodeling.
- Phorbol myristate acetate mediates redistribution of protein kinase C in human neutrophils: potential role in the activation of the respiratory burst enzyme.
- Phosphorylation of Nox1 regulates association with NoxA1 activation domain.
- Platelet-derived growth factor (PDGF) regulates Slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells.
- Production of superoxide anion by an NADPH-oxidase from rat pulmonary macrophages.
- Protection from nitrosative stress: a central role for microbial flavohemoglobin.
- Reduction in pulmonary and hepatic respiratory cytochrome contents by fly ash inhalation in rats.
- Role for Nox1 NADPH oxidase in atherosclerosis.
- Siroheme: a prosthetic group of the Neurospora crassa assimilatory nitrite reductase.
- Spinach siroheme enzymes: Isolation and characterization of ferredoxin-sulfite reductase and comparison of properties with ferredoxin-nitrite reductase.
- The NADPH oxidase of human polymorphonuclear leukocytes. Evidence for regulation by multiple signals.
- Unsaturated fatty acids and lipoxygenase products regulate phagocytic NADPH oxidase activity by a nondetergent mechanism.