Neisseria gonorrhoeae

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  Subject Areas on Research

  • A novel relaxase homologue is involved in chromosomal DNA processing for type IV secretion in Neisseria gonorrhoeae. 
  • Analysis of the potential for point-of-care test to enable individualised treatment of infections caused by antimicrobial-resistant and susceptible strains of Neisseria gonorrhoeae : a modelling study. 
  • Analytical Evaluation of the Abbott RealTime CT/NG Assay for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae in Rectal and Pharyngeal Swabs. 
  • Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting. 
  • Chaperone-assisted assembly and molecular architecture of adhesive pili. 
  • Characterisation of Neisseria gonorrhoeae in semen during urethral infection in men. 
  • Characterization of the multiple transferable resistance repressor, MtrR, from Neisseria gonorrhoeae. 
  • Clinical chorioamnionitis is not predicted by an ultrasonic biophysical profile in patients with premature rupture of membranes. 
  • Culture of non-genital sites increases the detection of gonorrhea in women. 
  • Disseminated gonococcal infections (DGI). 
  • Effects of Sexual Network Connectivity and Antimicrobial Drug Use on Antimicrobial Resistance in Neisseria gonorrhoeae. 
  • Evidence of Fe3+ interaction with the plug domain of the outer membrane transferrin receptor protein of Neisseria gonorrhoeae: implications for Fe transport. 
  • Ex vivo analysis of synergistic anion binding to FbpA in Gram-negative bacteria. 
  • Familial deficiency of the seventh component of complement associated with recurrent bacteremic infections due to Neisseria. 
  • FbpA--a bacterial transferrin with more to offer. 
  • Genetically engineered probiotic competition. 
  • Gonococcal endocarditis: a new look at an old disease. 
  • Gonococcal lipooligosaccharide suppresses HIV infection in human primary macrophages through induction of innate immunity. 
  • Hijacking transferrin bound iron: protein-receptor interactions involved in iron transport in N. gonorrhoeae. 
  • Human experimentation with Neisseria gonorrhoeae: rationale, methods, and implications for the biology of infection and vaccine development. 
  • Infection of artificial air pouches in the connective tissue of mice with Neisseria gonorrhoeae. 
  • Innate immune mediator profiles and their regulation in a novel polarized immortalized epithelial cell model derived from human endocervix. 
  • Kinetics and mechanism of exogenous anion exchange in FeFbpA-NTA: significance of periplasmic anion lability and anion binding activity of ferric binding protein A. 
  • Mating pair formation homologue TraG is a variable membrane protein essential for contact-independent type IV secretion of chromosomal DNA by Neisseria gonorrhoeae. 
  • Meningococcal Detoxified Outer Membrane Vesicle Vaccines Enhance Gonococcal Clearance in a Murine Infection Model. 
  • Multiple gonococcal opacity proteins are expressed during experimental urethral infection in the male. 
  • Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3-β4 loop to favor a low-affinity drug-binding state. 
  • Neisseria gonorrhoeae FitA interacts with FitB to bind DNA through its ribbon-helix-helix motif. 
  • Neisseria gonorrhoeae endocarditis on a prosthetic valve. 
  • Neisseria gonorrhoeae enhances HIV-1 infection of primary resting CD4+ T cells through TLR2 activation. 
  • Neisseria gonorrhoeae foot abscess. A case report. 
  • Neisseria gonorrhoeae strains inhibited by vancomycin in selective media and correlation with auxotype. 
  • Neisseria gonorrhoeae-induced human defensins 5 and 6 increase HIV infectivity: role in enhanced transmission. 
  • Neisseria meningitidis and Neisseria gonorrhoeae bacteremia associated with C6, C7, or C8 deficiency. 
  • Pelvic inflammatory disease. 
  • Preclinical Testing of Vaccines and Therapeutics for Gonorrhea in Female Mouse Models of Lower and Upper Reproductive Tract Infection. 
  • SUPREX (Stability of Unpurified Proteins from Rates of H/D Exchange) analysis of the thermodynamics of synergistic anion binding by ferric-binding protein (FbpA), a bacterial transferrin. 
  • Serogrouping of Neisseria gonorrhoeae: correlation of serogroup with disseminated gonococcal infection. 
  • Simultaneous Evaluation of Diagnostic Assays for Pharyngeal and Rectal Neisseria gonorrhoeae and Chlamydia trachomatis Using a Master Protocol. 
  • Structural, Biochemical, and In Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae. 
  • Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. 
  • Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations. 
  • Sulfate as a synergistic anion facilitating iron binding by the bacterial transferrin FbpA: the origins and effects of anion promiscuity. 
  • Test-of-Cure After Treatment of Pharyngeal Gonorrhea in Durham, North Carolina, 2021-2022. 
  • The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae. 
  • The varied manifestations of disseminated gonococcal infection. 
  • Time required for elimination of Neisseria gonorrhoeae from the urogenital tract in men with symptomatic urethritis: comparison of oral and intramuscular single-dose therapy. 
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  Keywords of People

  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Integrative Immunobiology