Neoplasm Invasiveness

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  Subject Areas on Research

  • 111-In-capromab pendetide imaging using hybrid-γ camera-computer tomography technology is not reliable in detecting seminal vesicle invasion in patients with prostate cancer. 
  • 3D traction stresses activate protease-dependent invasion of cancer cells. 
  • A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer. 
  • A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer. 
  • A Risk Prediction Model Based on Lymph-Node Metastasis in Poorly Differentiated-Type Intramucosal Gastric Cancer. 
  • A SAGE (serial analysis of gene expression) view of breast tumor progression. 
  • A clinical trial of neoadjuvant hyperthermic intravesical chemotherapy (HIVEC) for treating intermediate and high-risk non-muscle invasive bladder cancer. 
  • A large planum sphenoidale meningioma with sinonasal extension in a child. Case report and review of the literature. 
  • A latent model for prioritization of SNPs for functional studies. 
  • A neural survival factor is a candidate oncogene in breast cancer. 
  • A novel EGFR isoform confers increased invasiveness to cancer cells. 
  • A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity. 
  • A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth. 
  • A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion. 
  • A pharmacological study of celecoxib and gemcitabine in patients with advanced pancreatic cancer. 
  • A phase II study of pazopanib in patients with recurrent or metastatic invasive breast carcinoma: a trial of the Princess Margaret Hospital phase II consortium. 
  • A pilot clinical trial of intravesical mitomycin-C and external deep pelvic hyperthermia for non-muscle-invasive bladder cancer. 
  • A prognostic index for natural killer cell lymphoma after non-anthracycline-based treatment: a multicentre, retrospective analysis. 
  • A proposed new international TNM staging system for malignant pleural mesothelioma. From the International Mesothelioma Interest Group. 
  • A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion. 
  • A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase. 
  • A thin-layer model for viscoelastic, stress-relaxation testing of cells using atomic force microscopy: do cell properties reflect metastatic potential? 
  • A transcriptional repressor of osteopontin expression in the 4T1 murine breast cancer cell line. 
  • ACR Appropriateness Criteria(®) Locoregional therapy for resectable oropharyngeal squamous cell carcinomas. 
  • ACR Appropriateness Criteria® Post-Treatment Surveillance of Bladder Cancer. 
  • ACR Appropriateness Criteria® Pretreatment Staging of Muscle-Invasive Bladder Cancer. 
  • ACR Appropriateness Criteria® ipsilateral radiation for squamous cell carcinoma of the tonsil. 
  • ACR Appropriateness criteria® for nasopharyngeal carcinoma. 
  • AJAP1 expression modulates glioma cell motility and correlates with tumor growth and survival. 
  • ALK-negative anaplastic large cell lymphoma with extensive peripheral blood and bone marrow involvements manifested as "leukemic phase". 
  • ARID1A-mutated ovarian cancers depend on HDAC6 activity. 
  • Abdominal magnetic resonance imaging at 3 T: oncological applications. 
  • Abiraterone acetate for patients with metastatic castration-resistant prostate cancer progressing after chemotherapy: final analysis of a multicentre, open-label, early-access protocol trial. 
  • Abl kinases are required for invadopodia formation and chemokine-induced invasion. 
  • Absence of Tumor on Repeat Transurethral Resection of Bladder Tumor Does Not Predict Final Pathologic T0 Stage in Bladder Cancer Treated with Radical Cystectomy. 
  • Accuracy of intraoperative gross examination of surgical margin status in women undergoing partial mastectomy for breast malignancy. 
  • Accurate staging for gallbladder cancer: implications for surgical therapy and pathological assessment. 
  • Activation of Rap1 promotes prostate cancer metastasis. 
  • Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation. 
  • Actual 10-Year Survivors After Resection of Hepatocellular Carcinoma. 
  • Adenocarcinoma of the prostate. I. Tissue sampling considerations. 
  • Adenoid cystic carcinoma of the paranasal sinuses. 
  • Adenovirus-mediated antisense urokinase-type plasminogen activator receptor gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines. 
  • Adjuvant and salvage radiotherapy after prostatectomy: AUA/ASTRO Guideline. 
  • Adverse events associated with laparoscopy vs laparotomy in the treatment of endometrial cancer. 
  • Age- and sex-specific genomic profiles in non-small cell lung cancer. 
  • Aggressive Phenotype of Intravascular Lymphoma Relative to Other Malignant Intraabdominal Tumors Requiring Vascular Reconstruction. 
  • Aggressive multimodality treatment of invasive thymic carcinoma. 
  • All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy. 
  • Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer. 
  • Amplification and overexpression of PPFIA1, a putative 11q13 invasion suppressor gene, in head and neck squamous cell carcinoma. 
  • Amplification of telomeric DNA directly correlates with metastatic potential of human and murine cancers of various histological origin. 
  • An update on noninvasive follicular thyroid neoplasm with papillary-like nuclear features. 
  • Androgen-independent prostate cancer progression in the TRAMP model. 
  • Angiotropism of human prostate cancer cells: implications for extravascular migratory metastasis. 
  • Anterior Chamber Angle Invasion of Iridociliary Melanoma. 
  • Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma. 
  • Antiadenovirus Antibodies Predict Response Durability to Nadofaragene Firadenovec Therapy in BCG-unresponsive Non-muscle-invasive Bladder Cancer: Secondary Analysis of a Phase 3 Clinical Trial. 
  • Apical soft tissue biopsies predict biochemical failure in radical perineal prostatectomy patients with apical cancer involvement. 
  • Application of posterior neck dissection in treating malignant melanoma of the posterior scalp. 
  • Aspartyl-(asparaginyl)-beta-hydroxylase regulates hepatocellular carcinoma invasiveness. 
  • Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer. 
  • Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer. 
  • Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies. 
  • Association between preoperative erectile dysfunction and prostate cancer features--an analysis from the Duke Prostate Center Database. 
  • Association between ratio of matrix metalloproteinase-1 to tissue inhibitor of metalloproteinase-1 and local recurrence, metastasis, and survival in human chondrosarcoma. 
  • Association of cigarette smoking with interval to biochemical recurrence after radical prostatectomy: results from the SEARCH database. 
  • Association of distant recurrence-free survival with algorithmically extracted MRI characteristics in breast cancer. 
  • Association of plasminogen with dipeptidyl peptidase IV and Na+/H+ exchanger isoform NHE3 regulates invasion of human 1-LN prostate tumor cells. 
  • Associations Between Female Sex and Treatment Patterns and Outcomes for Muscle-invasive Bladder Cancer. 
  • Associations between lymphovascular space invasion, nodal recurrence, and survival in patients with surgical stage I endometrioid endometrial adenocarcinoma. 
  • Associations between methylation of paternally expressed gene 3 (PEG3), cervical intraepithelial neoplasia and invasive cervical cancer. 
  • Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases. 
  • Atypical pituitary adenoma: a clinicopathologic case series. 
  • BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers. 
  • Bevacizumab in combination with fluorouracil and leucovorin: an active regimen for first-line metastatic colorectal cancer. 
  • Beyond Depth of Invasion: Adverse Pathologic Tumor Features in Early Oral Tongue Squamous Cell Carcinoma. 
  • Bladder Cancer, Version 5.2017, NCCN Clinical Practice Guidelines in Oncology. 
  • Bladder cancer: race differences in extent of disease at diagnosis. 
  • Bone morphogenetic proteins induce pancreatic cancer cell invasiveness through a Smad1-dependent mechanism that involves matrix metalloproteinase-2. 
  • Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model. 
  • Borderline resectable pancreatic cancer: definitions, management, and role of preoperative therapy. 
  • Bradykinin receptor subtype 1 expression and function in prostate cancer. 
  • Breast cancer. Clinical practice guidelines in oncology. 
  • Breast carcinomas arising at a young age: unique biology or a surrogate for aggressive intrinsic subtypes? 
  • CHML promotes liver cancer metastasis by facilitating Rab14 recycle. 
  • CT of pectoralis muscle invasion by breast carcinoma. 
  • Can Occult Invasive Disease in Ductal Carcinoma In Situ Be Predicted Using Computer-extracted Mammographic Features? 
  • Can algorithmically assessed MRI features predict which patients with a preoperative diagnosis of ductal carcinoma in situ are upstaged to invasive breast cancer? 
  • Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin. 
  • Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk. 
  • Carcinoma of the vulva: combined modality treatment. 
  • Caspase-3 regulates the migration, invasion and metastasis of colon cancer cells. 
  • Cell adhesion: separation of p120's powers? 
  • Cell invasion through basement membranes: an anchor of understanding. 
  • Cellular migration and invasion uncoupled: increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition. 
  • Cervical carcinoma: determination of recurrent tumor extent versus radiation changes with MR imaging. 
  • Cervical intraepithelial neoplasia in HIV-infected women in a southeastern US population. 
  • Changing the Rules of Resectability of T4b Esophageal Cancer Invading Aorta. 
  • Characteristics Associated with Pathologic Nodal Burden in Patients Presenting with Clinical Melanoma Nodal Metastasis. 
  • Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2. 
  • Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis. 
  • Chemotherapy enriches for an invasive triple-negative breast tumor cell subpopulation expressing a precursor form of N-cadherin on the cell surface. 
  • CircIRAK3 sponges miR-3607 to facilitate breast cancer metastasis. 
  • Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages. 
  • Cisplatin but not BCNU inhibits urokinase-type plasminogen activator levels in human glioblastoma cell lines in vitro. 
  • Clinical characteristics of testicular extramedullary involvement in multiple myeloma. 
  • Clinical criteria for integrated molecular pathology in intraductal papillary mucinous neoplasm: less is more. 
  • Clinical problem solving: monster on the hook--case problems in neurosurgery. 
  • Clinical trial of high dose hyperthermic intravesical mitomycin C for intermediate and high-risk non-muscle invasive bladder cancer during BCG shortage. 
  • Clinical-pathological features and treatment modalities associated with recurrence in DCIS and micro-invasive carcinoma: Who to treat more and who to treat less. 
  • Clinicopathological Features and Prognosis of Mixed-Type T1a Gastric Cancer Based on Lauren's Classification. 
  • Combining biological gene expression signatures in predicting outcome in breast cancer: An alternative to supervised classification. 
  • Common variation in Nemo-like kinase is associated with risk of ovarian cancer. 
  • Comparison of Neoadjuvant and Adjuvant Chemotherapy in Muscle-invasive Bladder Cancer. 
  • Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancer. 
  • Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice. 
  • Concurrent chemoradiotherapy for locally advanced, nonmetastatic, squamous carcinoma of the head and neck: consensus, controversy, and conundrum. 
  • Confirmatory Magnetic Resonance Imaging with or without Biopsy Impacts Decision Making in Newly Diagnosed Favorable Risk Prostate Cancer. 
  • Congenital, infiltrating giant-cell angioblastoma. A new entity? 
  • Consensus report of the national cancer institute clinical trials planning meeting on pancreas cancer treatment. 
  • Constitutively active erythropoietin receptor expression in breast cancer cells promotes cellular proliferation and migration through a MAP-kinase dependent pathway. 
  • Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades. 
  • Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes. 
  • Curative Treatment for Muscle Invasive Bladder Cancer in Elderly Patients: A Systematic Review. 
  • Cutaneous melanoma of the head and neck. A review of 399 cases. 
  • Cyclocreatine inhibits stimulated motility in tumor cells possessing creatine kinase. 
  • Cytosolic TMEM88 promotes invasion and metastasis in lung cancer cells by binding DVLS. 
  • DCIS with Microinvasion: Is It In Situ or Invasive Disease? 
  • Decision Regret Related to Urinary Diversion Choice among Patients Treated with Cystectomy. 
  • Defining the Incremental Utility of Prostate Multiparametric Magnetic Resonance Imaging at Standard and Specialized Read in Predicting Extracapsular Extension of Prostate Cancer. 
  • Deletion of the p16INK4a tumor suppressor and expression of the androgen receptor induce sarcomatoid carcinomas with signet ring cells in the mouse prostate. 
  • Depth of Muscularis Propria Invasion Does Not Prognosticate Survival in T2 Esophageal Adenocarcinoma. 
  • Derlin-1 is overexpressed in non-small cell lung cancer and promotes cancer cell invasion via EGFR-ERK-mediated up-regulation of MMP-2 and MMP-9. 
  • Detailed pathologic characteristics of the primary colorectal tumor independently predict outcome after hepatectomy for metastases. 
  • Development and Validation of a Multi-institutional Preoperative Nomogram for Predicting Grade of Dysplasia in Intraductal Papillary Mucinous Neoplasms (IPMNs) of the Pancreas: A Report from The Pancreatic Surgery Consortium. 
  • Diagnostic and therapeutic implications of a novel immunohistochemical panel detecting duodenal mucosal invasion by pancreatic ductal adenocarcinoma. 
  • Differences in imaging characteristics of HPV-positive and HPV-Negative oropharyngeal cancers: a blinded matched-pair analysis. 
  • Differential expression of the 67-kD laminin receptor and 31-kD human laminin-binding protein in human ovarian carcinomas. 
  • Differential osteopontin expression in phenotypically distinct subclones of murine breast cancer cells mediates metastatic behavior. 
  • Diffuse infiltrating retinoblastoma presenting as a spontaneous hyphema. 
  • Diffuse infiltrating retinoblastoma simulating uveitis in a 7-year-old boy. 
  • Diffuse large B-cell lymphoma with Dutcher bodies. 
  • Dipeptidyl peptidase IV (DPP IV/CD26) is a cell-surface plasminogen receptor. 
  • Direct invasion of the transverse colon by a cecal tumor. 
  • Discovery and verification of protein differences between Er positive/Her2/neu negative breast tumor tissue and matched adjacent normal breast tissue. 
  • Distinctions in Breast Tumor Recurrence Patterns Post-Therapy among Racially Distinct Populations. 
  • Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells. 
  • Do All Positive Margins in Breast Cancer Patients Undergoing a Partial Mastectomy Need to Be Resected? 
  • Does Breast Density Increase the Risk of Re-excision for Women with Breast Cancer Having Breast-Conservation Therapy? 
  • Does a positive neural margin affect outcome in facial nerve grafting? 
  • Does of stage pT0 cystectomy specimen confer a survival advantage in patients with minimally invasive bladder cancer? 
  • Does vocal cord fixation preclude nonsurgical management of laryngeal cancer? 
  • Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells. 
  • Down-regulation of platelet-derived growth factor-D inhibits cell growth and angiogenesis through inactivation of Notch-1 and nuclear factor-kappaB signaling. 
  • Dynamic prediction of metastases after radical prostatectomy for prostate cancer. 
  • E-cadherin in gastric carcinomas: Relations with histological parameters and its prognostic value. 
  • EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma. 
  • Early Adoption of the SSO-ASTRO Consensus Guidelines on Margins for Breast-Conserving Surgery with Whole-Breast Irradiation in Stage I and II Invasive Breast Cancer: Initial Experience from Memorial Sloan Kettering Cancer Center. 
  • Early gastric cancer with a mixed-type Lauren classification is more aggressive and exhibits greater lymph node metastasis. 
  • Early outcomes of empiric embolization of tumor-related gastrointestinal hemorrhage in patients with advanced malignancy. 
  • Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro. 
  • Effect of surgeon specialization on long-term survival following colon cancer resection at an NCI-designated cancer center. 
  • Electrocardiographic pseudo-myocardial infarct pattern in malignant cardiac disease. 
  • Endoscopic ultrasonography in the diagnosis and staging of neoplasms of the head and neck. 
  • Endovascular management of carotid blowout. 
  • Enhancing dendritic cell-based vaccination for highly aggressive glioblastoma. 
  • EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase. 
  • Epidermal growth factor receptor variant III mediates head and neck cancer cell invasion via STAT3 activation. 
  • Epidermal growth factor receptor-related protein inhibits cell growth and invasion in pancreatic cancer. 
  • Epithelial cells are an important source of tenascin in normal and malignant human breast tissue. 
  • Estrogen receptor beta rs1271572 polymorphism and invasive ovarian carcinoma risk: pooled analysis within the Ovarian Cancer Association Consortium. 
  • Evaluation of 122 advanced-stage cutaneous squamous cell carcinomas by comprehensive genomic profiling opens the door for new routes to targeted therapies. 
  • Evaluation of Pathologic Nipple Discharge: What is the Added Diagnostic Value of MRI? 
  • Evaluation of the Fluorescence In Situ Hybridization Test to Predict Recurrence and/or Progression of Disease after bacillus Calmette-Guérin for Primary High Grade Nonmuscle Invasive Bladder Cancer: Results from a Prospective Multicenter Trial. 
  • Everolimus versus sunitinib for patients with metastatic non-clear cell renal cell carcinoma (ASPEN): a multicentre, open-label, randomised phase 2 trial. 
  • Evidence of increased failure in the treatment of prostate carcinoma patients who have perineural invasion treated with three-dimensional conformal radiation therapy. 
  • Evidence-based Assessment of Current and Emerging Bladder-sparing Therapies for Non-muscle-invasive Bladder Cancer After Bacillus Calmette-Guerin Therapy: A Systematic Review and Meta-analysis. 
  • Exploring the Relationship Between Patient Age and Cancer-Specific Survival in Papillary Thyroid Cancer: Rethinking Current Staging Systems. 
  • Expression of the 67-kD laminin receptor, galectin-1, and galectin-3 in advanced human uterine adenocarcinoma. 
  • Extensive invasion of the left atrium by lung cancer. 
  • Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas. 
  • Extracapsular spread and the perineural extension of squamous cell cancer in the cervical plexus. 
  • Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation. 
  • FDG PET/CT in the management of primary pleural tumors and pleural metastases. 
  • FOXP3-positive regulatory T lymphocytes and epithelial FOXP3 expression in synchronous normal, ductal carcinoma in situ, and invasive cancer of the breast. 
  • Factors associated with survival in pediatric adrenocortical carcinoma: An analysis of the National Cancer Data Base (NCDB). 
  • Factors predicting prostatic biopsy Gleason sum under grading. 
  • Feasibility of hybrid thoracoscopic lobectomy and en-bloc chest wall resection. 
  • Features of occult invasion in biopsy-proven DCIS at breast MRI. 
  • First postoperative PSA is associated with outcomes in patients with node positive prostate cancer: Results from the SEARCH database. 
  • Five-year colon surveillance after screening colonoscopy. 
  • Flow cytometric DNA analysis of excised breast lesions: use of fresh tissue needle aspirates obtained under guidance with mammography of the specimen. 
  • Flow cytometric determination of ploidy in prostatic adenocarcinoma: a comparison with seminal vesicle involvement and histopathological grading as a predictor of clinical recurrence. 
  • Focal therapy of prostate cancer: evidence-based analysis for modern selection criteria. 
  • Functional CD3+CD8+PD1- T Cell Accumulation and PD-L1 Expression Increases During Tumor Invasion in DCIS of the Breast. 
  • G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis. 
  • G1 checkpoint protein and p53 abnormalities occur in most invasive transitional cell carcinomas of the urinary bladder. 
  • G12 signaling through c-Jun NH2-terminal kinase promotes breast cancer cell invasion. 
  • GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling. 
  • GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. 
  • Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. 
  • Gene set analysis of survival following ovarian cancer implicates macrolide binding and intracellular signaling genes. 
  • Genetically predicted circulating protein biomarkers and ovarian cancer risk. 
  • Genome-wide linkage scan for prostate cancer aggressiveness loci using families from the University of Michigan Prostate Cancer Genetics Project. 
  • Glomus jugulare tumors with intracranial extension. 
  • Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms. 
  • Glucose-regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders. 
  • Grading of well-differentiated pancreatic neuroendocrine tumors is improved by the inclusion of both Ki67 proliferative index and mitotic rate. 
  • HEPSIN inhibits cell growth/invasion in prostate cancer cells. 
  • HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites. 
  • Health-related quality of life among non-muscle-invasive bladder cancer survivors: a population-based study. 
  • Hepatic imaging characteristics predict overall survival in hepatocellular carcinoma. 
  • High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype. 
  • High-dose therapy with hematopoietic cell transplantation for patients with central nervous system involvement by non-Hodgkin's lymphoma. 
  • Histologic pattern of invasion and epithelial-mesenchymal phenotype predict prognosis in squamous carcinoma of the head and neck. 
  • Histologic tumor involvement of superior mesenteric vein/portal vein predicts poor prognosis in patients with stage II pancreatic adenocarcinoma treated with neoadjuvant chemoradiation. 
  • Histone methyltransferase SETDB1 is required for prostate cancer cell proliferation, migration and invasion. 
  • How Long Should Patients with Cystic Lesions of the Pancreas Be Followed? 
  • How well does the new lung cancer staging system predict for local/regional recurrence after surgery?: A comparison of the TNM 6 and 7 systems. 
  • Human Immunodeficiency Virus (HIV)- and Non-HIV-Associated Immunosuppression and Risk of Cervical Neoplasia. 
  • Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration. 
  • Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer. 
  • I-CLIP: improved stratification of advanced hepatocellular carcinoma patients by integrating plasma IGF-1 into CLIP score. 
  • IFN-{beta} signaling positively regulates tumorigenesis in aggressive fibromatosis, potentially by modulating mesenchymal progenitors. 
  • Identical-twin small-bowel transplant for desmoid tumour. 
  • Identification and Functional Validation of Reciprocal microRNA-mRNA Pairings in African American Prostate Cancer Disparities. 
  • Identification of higher risk thin melanomas should be based on Breslow depth not Clark level IV. 
  • Identifying new small molecule anti-invasive compounds for glioma treatment. 
  • Immunoreaction at 43 kDa with anti-ubiquitin antibody in breast neoplasms. 
  • Immunotherapeutic agents for the management of BCG refractory non-muscle invasive bladder cancer. 
  • Impact of Positive Margins on Survival in Patients Undergoing Esophagogastrectomy for Esophageal Cancer. 
  • Impact of primary Gleason grade on risk stratification for Gleason score 7 prostate cancers. 
  • Improvements in pathologic staging for African-American men undergoing radical retropubic prostatectomy during the prostate specific antigen era: implications for screening a high-risk group for prostate carcinoma. 
  • In vivo identification of regulators of cell invasion across basement membranes. 
  • In vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma. 
  • Incidence of Adjacent Synchronous Invasive Carcinoma and/or Ductal Carcinoma In-situ in Patients with Lobular Neoplasia on Core Biopsy: Results from a Prospective Multi-Institutional Registry (TBCRC 020). 
  • Increasing use of positron emission tomography among medicare beneficiaries undergoing radical cystectomy. 
  • Influence of wide excision of the neurovascular bundle(s) on prognosis in men with clinically localized prostate cancer with established capsular penetration. 
  • Inhibition of c-Met as a therapeutic strategy for esophageal adenocarcinoma. 
  • Inhibition of gastric cancer invasion and metastasis by PLA2G2A, a novel beta-catenin/TCF target gene. 
  • Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway. 
  • Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases. 
  • Integrative genomics identifies RAB23 as an invasion mediator gene in diffuse-type gastric cancer. 
  • Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells. 
  • International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 3: extraprostatic extension, lymphovascular invasion and locally advanced disease. 
  • International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. 
  • Interobserver agreement on what constitutes visceral pleural invasion by non-small cell lung carcinoma: an internet-based assessment of international current practices. 
  • Interstitial flow in a 3D microenvironment increases glioma invasion by a CXCR4-dependent mechanism. 
  • Interstitial implant alone or in combination with external beam radiation therapy for intermediate-risk prostate cancer: a survey of practice patterns in the United States. 
  • Intraductal Oncocytic Papillary Neoplasms: Clinical-Pathologic Characterization of 24 Cases, With An Emphasis on Associated Invasive Carcinomas. 
  • Intraductal Papillary Mucinous Neoplasm of the Pancreas in Young Patients: Tumor Biology, Clinical Features, and Survival Outcomes. 
  • Intraductal papillary mucinous neoplasm. 
  • Intraductal papillary mucinous neoplasms of the pancreas: effect of invasion and pancreatic margin status on recurrence and survival. 
  • Intraductal papillary neoplasm of the bile duct: a biliary equivalent to intraductal papillary mucinous neoplasm of the pancreas? 
  • Intraoperative transesophageal echocardiography diagnosis of residual tumor fragment after surgical removal of renal cell carcinoma. 
  • Intrathoracic metastasis from an extrathoracic malignancy: a radiographic approach to patient evaluation. 
  • Intratumoral and peritumoral lymphovascular invasion detected by D2-40 immunohistochemistry correlates with metastasis in primary cutaneous Merkel cell carcinoma. 
  • Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial. 
  • Intravesical rAd-IFNα/Syn3 for Patients With High-Grade, Bacillus Calmette-Guerin-Refractory or Relapsed Non-Muscle-Invasive Bladder Cancer: A Phase II Randomized Study. 
  • Invasion and MMP expression profile in desmoid tumours. 
  • Invasion of the internal carotid artery by cavernous sinus meningiomas. 
  • Invasion of uterine cervical squamous cell carcinoma cells is facilitated by locoregional interaction with cancer-associated fibroblasts via activating transforming growth factor-beta. 
  • Invasive Breast Cancer Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. 
  • Invasive Cell Fate Requires G1 Cell-Cycle Arrest and Histone Deacetylase-Mediated Changes in Gene Expression. 
  • Invasive Epithelial Ovarian Cancer Survival by Histotype and Disease Stage. 
  • Invasive breast cancer. 
  • Invasive carcinoma arising in intraductal papillary mucinous neoplasms of the pancreas: a matched control study with conventional pancreatic ductal adenocarcinoma. 
  • Invasive prostate carcinoma driven by c-Src and androgen receptor synergy. 
  • Invasiveness is associated with metastasis and decreased survival in hemangiopericytoma of the central nervous system. 
  • Invasiveness of human glioma cell lines in vitro: relation to tumorigenicity in athymic mice. 
  • Iris melanoma: risk factors for metastasis in 169 consecutive patients. 
  • Is computed tomography a necessary part of a metastatic evaluation for castration-resistant prostate cancer? Results from the Shared Equal Access Regional Cancer Hospital Database. 
  • Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin β3 recycling, cell migration and cancer metastasis. 
  • Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer. 
  • LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis. 
  • Lack of expression of androgen receptor may play a critical role in transformation from in situ to invasive basal subtype of high-grade ductal carcinoma of the breast. 
  • Laparoscopy-assisted robotic radical cystoprostatectomy with ileal conduit urinary diversion for muscle-invasive bladder cancer: initial two cases. 
  • Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome. 
  • Late intrascrotal metastases from renal cell carcinoma. 
  • Leukaemia: a model metastatic disease. 
  • Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer. 
  • Local failure in resected N1 lung cancer: implications for adjuvant therapy. 
  • Local therapy for rectal cancer. 
  • Localized malignant mesothelioma. 
  • Long term cost comparisons of radical cystectomy versus trimodal therapy for muscle-invasive bladder cancer. 
  • Long-term outcomes after lobectomy for non-small cell lung cancer when unsuspected pN2 disease is found: A National Cancer Data Base analysis. 
  • Loss of MST/Hippo Signaling in a Genetically Engineered Mouse Model of Fusion-Positive Rhabdomyosarcoma Accelerates Tumorigenesis. 
  • Loss of betaglycan expression in ovarian cancer: role in motility and invasion. 
  • Loss of carbamoyl phosphate synthetase I in small-intestinal adenocarcinoma. 
  • Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity. 
  • Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate. 
  • Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2. 
  • Loss of type III transforming growth factor beta receptor expression increases motility and invasiveness associated with epithelial to mesenchymal transition during pancreatic cancer progression. 
  • Lymphomas or leukemia presenting as ovarian tumors. An analysis of 42 cases. 
  • Lymphovascular invasion in non-small-cell lung cancer: implications for staging and adjuvant therapy. 
  • Lymphovascular space invasion in uterine corpus cancer: What is its prognostic significance in the absence of lymph node metastases? 
  • MRI of gangliocytoma of cerebellum and spinal cord. 
  • MRS measured fatty acid composition of periprostatic adipose tissue correlates with pathological measures of prostate cancer aggressiveness. 
  • Magnetic resonance imaging in patients diagnosed with ductal carcinoma-in-situ: value in the diagnosis of residual disease, occult invasion, and multicentricity. 
  • Maintenance of DNA content and erbB-2 alterations in intraductal and invasive phases of mammary cancer. 
  • Maintenance of p53 alterations throughout breast cancer progression. 
  • Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells. 
  • Major vascular resection as part of pancreaticoduodenectomy for cancer: radiologic, intraoperative, and pathologic analysis. 
  • Malignant biliary obstruction: efficacy of thin-section dynamic CT in determining resectability. 
  • Malignant progression in IPMN: a cohort analysis of patients initially selected for resection or observation. 
  • Management of ductal carcinoma in situ. 
  • Management of locally advanced adenocarcinoma of the pancreas. 
  • Management of pediatric nasal dermoids with intracranial extension by direct excision. 
  • Marshall Urist Award. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma. 
  • Massive extraocular extension as the presenting feature of a choroidal melanoma. 
  • Matrix metalloproteinase activity modulates tumor size, cell motility, and cell invasiveness in murine aggressive fibromatosis. 
  • Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer. 
  • Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines. 
  • Mechanisms of action of rapamycin in gliomas. 
  • Melanoma of the foot. 
  • Melanoma-derived conditioned media efficiently induce the differentiation of monocytes to macrophages that display a highly invasive gene signature. 
  • Merkel cell carcinoma: identification of prognostic factors unique to tumors located in the head and neck based on analysis of SEER data. 
  • Mesenchymal-Epithelial Transition in Sarcomas Is Controlled by the Combinatorial Expression of MicroRNA 200s and GRHL2. 
  • Met and hepatocyte growth factor/scatter factor expression in human gliomas. 
  • Metastatic squamous cell carcinoma of the nasal tip: a case report. 
  • MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer. 
  • Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines. 
  • MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma. 
  • MicroRNA-182 and microRNA-200a control G-protein subunit α-13 (GNA13) expression and cell invasion synergistically in prostate cancer cells. 
  • MicroRNA-31 controls G protein alpha-13 (GNA13) expression and cell invasion in breast cancer cells. 
  • MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar Carcinoma. 
  • Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas. 
  • Minimal barriers to invasion during human colorectal tumor growth. 
  • Minimally invasive follicular carcinoma: predictors of vascular invasion and impact on patterns of care. 
  • Mitochondrial Superoxide Dismutase Has a Protumorigenic Role in Ovarian Clear Cell Carcinoma. 
  • Modeling the Early Steps of Ovarian Cancer Dissemination in an Organotypic Culture of the Human Peritoneal Cavity. 
  • Modulation of in vitro invasion of human glioblastoma cells by urokinase-type plasminogen activator receptor antibody. 
  • Molecular characterization of the tumor-suppressive function of nischarin in breast cancer. 
  • Molecular classification of cutaneous malignant melanoma by gene expression profiling. 
  • Monopolar vs. bipolar transurethral resection for non-muscle invasive bladder carcinoma: A post-hoc analysis from a randomized controlled trial. 
  • Mouse-INtraDuctal (MIND): an in vivo model for studying the underlying mechanisms of DCIS malignancy. 
  • Mucosal melanoma. 
  • Multidisciplinary Management of the Axilla in Patients with cT1-T2 N0 Breast Cancer Undergoing Primary Mastectomy: Results from a Prospective Single-Institution Series. 
  • Multiply recurrent trichilemmal carcinoma with perineural invasion and cytokeratin 17 positivity. 
  • Multivariable analysis of DNA ploidy, p53, and HER-2/neu as prognostic factors in endometrial cancer. 
  • Muscle-invasive transitional cell carcinoma of the renal pelvis visualized and biopsied via semirigid ureteroscopy. 
  • Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion. 
  • Myoepithelial-specific CD44 shedding contributes to the anti-invasive and antiangiogenic phenotype of myoepithelial cells. 
  • N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells. 
  • N-terminal 1-54 amino acid sequence and Armadillo repeat domain are indispensable for P120-catenin isoform 1A in regulating E-cadherin. 
  • NCCN Guidelines® Insights: Bladder Cancer, Version 2.2022. 
  • NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. 
  • Need for Evidence and Consensus on Laser Treatment for Management of Select Primary Penile Tumors. 
  • Neoadjuvant Endocrine Therapy Versus Neoadjuvant Chemotherapy in Node-Positive Invasive Lobular Carcinoma. 
  • Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial. 
  • Neural network analysis of quantitative histological factors to predict pathological stage in clinical stage I nonseminomatous testicular cancer. 
  • Neutrophil-to-Lymphocyte Ratio as a Predictor of Invasive Carcinoma in Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas. 
  • Nitric oxide-dependent osteopontin expression induces metastatic behavior in HepG2 cells. 
  • Noninvasive Follicular Variant of Papillary Thyroid Carcinoma and the Afirma Gene-Expression Classifier. 
  • Number of Ribs Resected is Associated with Respiratory Complications Following Lobectomy with en bloc Chest Wall Resection. 
  • OVX1, macrophage-colony stimulating factor, and CA-125-II as tumor markers for epithelial ovarian carcinoma: a critical appraisal. 
  • Omental cakes in American Burkitt lymphoma. Computed tomography demonstration. 
  • Oncogene-dependent control of miRNA biogenesis and metastatic progression in a model of undifferentiated pleomorphic sarcoma. 
  • Optimal staging procedures, including imaging, to define prognosis of bladder cancer. 
  • Osteopontin up-regulates critical epithelial-mesenchymal transition transcription factors to induce an aggressive breast cancer phenotype. 
  • Outcomes and predictors of survival in cutaneous melanoma of the eyelid: An analysis of the National Cancer Database. 
  • Outcomes of living and deceased donor liver transplant recipients with hepatocellular carcinoma: results of the A2ALL cohort. 
  • Overexpression of human carcinoma-associated antigen in urothelial carcinoma of the bladder. 
  • Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma. 
  • Overexpression of the EMT driver brachyury in breast carcinomas: association with poor prognosis. 
  • Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells. 
  • Palliative surgery for head and neck cancer with extensive skin involvement. 
  • Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness. 
  • Pathologic and clinical tumor size discordance in early-stage cervical cancer: Does it matter? 
  • Patterns of chromosomal alterations in breast ductal carcinoma in situ. 
  • Patterns of failure after pancreaticoduodenectomy for ampullary carcinoma. 
  • Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers. 
  • Pediatric melanoma: a single-institution experience of 150 patients. 
  • Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial. 
  • Percentage of embryonal carcinoma and of vascular invasion predicts pathological stage in clinical stage I nonseminomatous testicular cancer. 
  • Percutaneous image-guided thermal ablation and radiation therapy: outcomes of combined treatment for 41 patients with inoperable stage I/II non-small-cell lung cancer. 
  • Pericardial synovial sarcoma: case report and literature review. 
  • Perineural and intraneural invasion in posttherapy pancreaticoduodenectomy specimens predicts poor prognosis in patients with pancreatic ductal adenocarcinoma. 
  • Perioperative Intravesical Chemotherapy for Patients WithNon-Muscle-invasive Bladder Cancer: Understanding the Extent of and Sources of Variation in Guideline-recommended Use. 
  • Perioperative Management of Adrenalectomy and Inferior Vena Cava Reconstruction in a Patient With a Large, Malignant Pheochromocytoma With Vena Caval Extension. 
  • Perioperative intravesical chemotherapy in non-muscle-invasive bladder cancer: a systematic review and meta-analysis. 
  • Peritoneal and subperitoneal stroma may facilitate regional spread of ovarian cancer. 
  • Peritumoral brain regions in gliomas and meningiomas: investigation with isotropic diffusion-weighted MR imaging and diffusion-tensor MR imaging. 
  • Persistent Pure Ground-Glass Nodules Larger Than 5 mm: Differentiation of Invasive Pulmonary Adenocarcinomas From Preinvasive Lesions or Minimally Invasive Adenocarcinomas Using Texture Analysis. 
  • Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies. 
  • Phase II Study of Gemcitabine and Split-Dose Cisplatin Plus Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Bladder Cancer. 
  • Phase II randomized trial of weekly paclitaxel with or without estramustine phosphate in progressive, metastatic, hormone-refractory prostate cancer. 
  • Phase II study of predictive biomarker profiles for response targeting human epidermal growth factor receptor 2 (HER-2) in advanced inflammatory breast cancer with lapatinib monotherapy. 
  • Phase III trial of neoadjuvant chemotherapy in patients with invasive bladder cancer treated with selective bladder preservation by combined radiation therapy and chemotherapy: initial results of Radiation Therapy Oncology Group 89-03. 
  • Polymer-Mediated Inhibition of Pro-invasive Nucleic Acid DAMPs and Microvesicles Limits Pancreatic Cancer Metastasis. 
  • Polymorphisms in BRCA1 and BRCA2 and risk of epithelial ovarian cancer. 
  • Positron emission tomography in radiation treatment planning: the potential of metabolic imaging. 
  • Postoperative radiotherapy of the prostate for patients undergoing radical prostatectomy with positive margins, seminal vesicle involvement and/or penetration through the capsule. 
  • Postradiation cerebellar necrosis mimicking tumor: MR appearance. 
  • Predicting Upstaging of DCIS to Invasive Disease: Radiologists's Predictive Performance. 
  • Predicting breast cancer invasion with artificial neural networks on the basis of mammographic features. 
  • Predicting dysplasia and invasive carcinoma in intraductal papillary mucinous neoplasms of the pancreas: development of a preoperative nomogram. 
  • Predicting microvascular invasion in hepatocellular carcinoma: A dual-institution study on gadoxetate disodium-enhanced MRI. 
  • Prediction of Hepatocellular Carcinoma Recurrence Beyond Milan Criteria After Resection: Validation of a Clinical Risk Score in an International Cohort. 
  • Predictors of extracapsular extension and positive margins in African American and white men. 
  • Preexisting Cardiovascular Risk and Subsequent Heart Failure Among Non-Hodgkin Lymphoma Survivors. 
  • Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis. 
  • Preoperative Cytologic Diagnosis of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: A Prospective Analysis. 
  • Preoperative Prediction of Microvascular Invasion in Hepatocellular Carcinoma Using Quantitative Image Analysis. 
  • Preoperative facial muscle imaging predicts final facial function after facial nerve grafting. 
  • Presurgical detection of brain invasion status in meningiomas based on first-order histogram based texture analysis of contrast enhanced imaging. 
  • Prevalence, characteristics, and outcomes of HIV-positive women diagnosed with invasive cancer of the cervix in Kenya. 
  • Primary high-grade neuroendocrine carcinoma of the esophagus: a clinicopathologic and immunohistochemical study of 42 resection cases. 
  • Primary malignant fibrous histiocytoma of the lung. A clinicopathologic and ultrastructural study of five cases. 
  • Primary systemic therapy in breast cancer: past lessons and new approaches. 
  • Primary tumor characteristics predict sentinel lymph node macrometastasis in breast cancer. 
  • Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the Ovarian Cancer Association Consortium pooled analysis. 
  • Prognosis significance of HER-2/neu overexpression/amplification in Chinese patients with curatively resected gastric cancer after the ToGA clinical trial. 
  • Prognostic indicators for survival in stage I carcinoma of the lung: a histologic study of 47 surgically resected cases. 
  • Prognostic risk factors in low stage testicular germ cell tumors: unanswered questions regarding clinically useful prognosticators for extratesticular disease. 
  • Prognostic risk factors that identify patients with clinical stage I nonseminomatous germ cell tumors at low risk and high risk for metastasis. 
  • Prognostic significance of depth of gross or microscopic perirectal fat invasion in T3 N0 M0 rectal cancers following sharp mesorectal excision and no adjuvant therapy. 
  • Prognostic significance of parapharyngeal space venous plexus and marrow involvement: potential landmarks of dissemination for stage I-III nasopharyngeal carcinoma. 
  • Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration. 
  • Prognostic value of contrast-enhanced magnetic resonance imaging in brainstem gliomas. 
  • Progression Patterns in the Remnant Pancreas after Resection of Non-Invasive or Micro-Invasive Intraductal Papillary Mucinous Neoplasms (IPMN). 
  • Proliferation index in various stages of breast cancer determined by Ki-67 immunostaining. 
  • Proper staging techniques in testicular cancer patients. 
  • Prospective phase II trial of pazopanib plus CapeOX (capecitabine and oxaliplatin) in previously untreated patients with advanced gastric cancer. 
  • Prostate cancer laterality as a rationale of focal ablative therapy for the treatment of clinically localized prostate cancer. 
  • Prostate cancer susceptibility polymorphism rs2660753 is not associated with invasive ovarian cancer. 
  • Prostate cancer: status of current treatments and emerging antisense-based therapies. 
  • Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism. 
  • Proteoglycan signaling co-receptors: roles in cell adhesion, migration and invasion. 
  • Protocol for the examination of specimens from patients with primary non-small cell carcinoma, small cell carcinoma, or carcinoid tumor of the lung. 
  • Race and risk of metastases and survival after radical prostatectomy: Results from the SEARCH database. 
  • Radical prostatectomy: value of prostate MRI in surgical planning. 
  • Radiology quiz case 2. Docetaxel (Taxotere)-induced photosensitivity. 
  • Radiotherapy regimens in patients with nonmelanoma head and neck skin cancers. 
  • Recent developments in defining microinvasive and early invasive carcinoma of the uterine cervix. 
  • Receptor activator of NF-κB (RANK)-mediated induction of metastatic spread and association with poor prognosis in renal cell carcinoma. 
  • Recombinant human uteroglobin inhibits the in vitro invasiveness of human metastatic prostate tumor cells and the release of arachidonic acid stimulated by fibroblast-conditioned medium. 
  • Rectal cancer: the sphincter-sparing approach. 
  • Recurrence after mastectomy for ductal carcinoma in situ. 
  • Recurrence and Survival After Resection of Small Intraductal Papillary Mucinous Neoplasm-associated Carcinomas (≤20-mm Invasive Component): A Multi-institutional Analysis. 
  • Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development. 
  • Regional spread of cutaneous squamous cell carcinoma of the face via facial vein tumor thrombus: a case report. 
  • Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells. 
  • Relationship between minimally invasive hysterectomy, pelvic cytology, and lymph vascular space invasion: a single institution study of 458 patients. 
  • Repair capacity for UV light induced DNA damage associated with risk of nonmelanoma skin cancer and tumor progression. 
  • Reproducibility of histopathological subtypes and invasion in pulmonary adenocarcinoma. An international interobserver study. 
  • Requirement of HDAC6 for transforming growth factor-beta1-induced epithelial-mesenchymal transition. 
  • Resection margin and survival in 2368 patients undergoing hepatic resection for metastatic colorectal cancer: surgical technique or biologic surrogate? 
  • Residual disease after radical surgery or radiation therapy for prostate cancer. Clinical significance and therapeutic implications. 
  • Retrospective analysis of the efficacy and safety of neoadjuvant gemcitabine and cisplatin in muscle-invasive bladder cancer. 
  • Role of G12 proteins in oncogenesis and metastasis. 
  • Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using an in vitro matrigel model. 
  • Roles for the type III TGF-beta receptor in human cancer. 
  • Rosai-Dorfman disease presenting with isolated bilateral orbital masses: report of two cases. 
  • SETD2 histone modifier loss in aggressive GI stromal tumours. 
  • SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression. 
  • Salvage Radiation Therapy Dose Response for Biochemical Failure of Prostate Cancer After Prostatectomy-A Multi-Institutional Observational Study. 
  • Selection of patients for heterotopic implantation of the areola and nipple. 
  • Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis. 
  • Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion. 
  • Selective upregulated expression of the alpha2-macroglobulin signaling receptor in highly metastatic 1-LN prostate carcinoma cells. 
  • Seminal vesicle intraepithelial involvement by prostate cancer: putative mechanism and clinicopathological significance. 
  • Sentinel node staging of resectable colon cancer: results of a multicenter study. 
  • Serum Antibodies to HPV16 Early Proteins Warrant Investigation as Potential Biomarkers for Risk Stratification and Recurrence of HPV-Associated Oropharyngeal Cancer. 
  • Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer. 
  • Side population cells isolated from mesenchymal neoplasms have tumor initiating potential. 
  • Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer. 
  • Sleep quality and prostate cancer aggressiveness: Results from the REDUCE trial. 
  • Sleeve lobectomy for non-small cell lung cancer with N1 nodal disease does not compromise survival. 
  • Small bowel obstruction after transoral robotic surgery. 
  • Snail promotes resistance to enzalutamide through regulation of androgen receptor activity in prostate cancer. 
  • Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer. 
  • Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer. 
  • Solid pseudopapillary neoplasm of the pancreas: clinicopathologic and survival analyses of 64 cases from a single institution. 
  • Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion. 
  • Spatial mutation patterns as markers of early colorectal tumor cell mobility. 
  • Sphincter-sparing surgery in patients with low-lying rectal cancer: techniques, oncologic outcomes, and functional results. 
  • Staging of esophageal cancer by EUS: staging accuracy revisited. 
  • Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis. 
  • Statin use and the risk of recurrence after radical prostatectomy in a cohort of men with inherited and/or early-onset forms of prostate cancer. 
  • Statistical modeling using preoperative prognostic variables in predicting extracapsular extension and progression after radical prostatectomy for prostate cancer. 
  • Sternal metastasis as first presentation of a well-differentiated papillary thyroid carcinoma. 
  • Sudden death from diffuse leptomeningeal oligodendrogliomatosis. 
  • Surgeon volume and adequacy of thyroidectomy for differentiated thyroid cancer. 
  • Surgical Resection is Justifiable for Oral T4b Squamous Cell Cancers With Masticator Space Invasion. 
  • Surgical Upstaging Rates for Vacuum Assisted Biopsy Proven DCIS: Implications for Active Surveillance Trials. 
  • Surgical management and prognosis of renal cell carcinoma invading the vena cava. 
  • Surgical management of petroclival meningiomas: defining resection goals based on risk of neurological morbidity and tumor recurrence rates in 137 patients. 
  • Surgical patterns of care in patients with invasive breast cancer treated with neoadjuvant systemic therapy and breast magnetic resonance imaging: results of a secondary analysis of TBCRC 017. 
  • Survival Outcomes in Sinonasal Poorly Differentiated Squamous Cell Carcinoma. 
  • Survival after resection of pancreatic adenocarcinoma: results from a single institution over three decades. 
  • Survival differences between patients with scalp or neck melanoma and those with melanoma of other sites in the Surveillance, Epidemiology, and End Results (SEER) program. 
  • Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers. 
  • T classification and clivus margin as risk factors for determining locoregional control by radiotherapy of nasopharyngeal carcinoma. 
  • TBR-760, a Dopamine-Somatostatin Compound, Arrests Growth of Aggressive Nonfunctioning Pituitary Adenomas in Mice. 
  • TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion. 
  • Targeted genomic CRISPR-Cas9 screen identifies MAP4K4 as essential for glioblastoma invasion. 
  • Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases. 
  • Targeting the Tie2/Tek receptor in astrocytomas. 
  • TbetaRIII suppresses non-small cell lung cancer invasiveness and tumorigenicity. 
  • Telomerase activity and prognosis in primary breast cancers. 
  • Telomerase activity in ductal carcinoma in situ and invasive breast cancer. 
  • Tenascin-C, over expressed in lung cancer down regulates effector functions of tumor infiltrating lymphocytes. 
  • The Association of Extent of Axillary Surgery and Survival in Women with N2-3 Invasive Breast Cancer. 
  • The Effects of Surgery Type and Chemotherapy on Early-Stage Breast Cancer Patients' Quality of Life Over 2-Year Follow-up. 
  • The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis. 
  • The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling. 
  • The Kraske procedure: a critical analysis of a surgical approach for mid-rectal lesions. 
  • The Pedunculated Pretender: A Case of Invasive Anorectal Mucosal Melanoma. 
  • The Role of Opioids and Their Receptors in Urological Malignancy: A Review. 
  • The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer. 
  • The anatomy of missed breast cancers. 
  • The biology of ovarian cancer. 
  • The detection of renal carcinoma extension into the renal vein and inferior vena cava: a prospective comparison of venacavography and magnetic resonance imaging. 
  • The diagnosis of desmoplastic malignant mesothelioma and its distinction from fibrous pleurisy: a histologic and immunohistochemical analysis of 31 cases including p53 immunostaining. 
  • The diagnosis of ovarian cancer by pathologists: how often do diagnoses by contributing pathologists agree with a panel of gynecologic pathologists? 
  • The estrogen receptor-alpha A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study. 
  • The expression of Claudin-4 in gastric cancer tissue: A single center experience. 
  • The impact of chemotherapy sequence on survival in node-positive invasive lobular carcinoma. 
  • The impact of portal vein resection on outcomes for hilar cholangiocarcinoma: a multi-institutional analysis of 305 cases. 
  • The impact of the social construct of race on outcomes among bacille Calmette-Guérin-treated patients with high-risk non-muscle-invasive bladder cancer in an equal-access setting. 
  • The influence of radiation modality and lymph node dissection on survival in early-stage endometrial cancer. 
  • The natural history of colorectal carcinoma in adolescents. 
  • The need for standardized pathologic staging of pancreaticoduodenectomy specimens. 
  • The outcome of stage I-II clinically and surgically staged papillary serous and clear cell endometrial cancers when compared with endometrioid carcinoma. 
  • The presence of human papillomavirus-16/-18 E6, p53, and Bcl-2 protein in cervicovaginal smears from patients with invasive cervical cancer. 
  • The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. 
  • The role of neoadjuvant chemotherapy, lymph node dissection, and treatment delay in patients with muscle-invasive bladder cancer undergoing partial cystectomy. 
  • The role of ultrasound-guided fine-needle aspiration of axillary nodes in the staging of breast cancer. 
  • The small abnormal parathyroid gland is increasingly common and heralds operative complexity. 
  • The superficial margin of the skin-sparing mastectomy for breast carcinoma: factors predicting involvement and efficacy of additional margin sampling. 
  • The tetraspanin superfamily member NET-6 is a new tumor suppressor gene. 
  • The type III TGF-beta receptor suppresses breast cancer progression through GIPC-mediated inhibition of TGF-beta signaling. 
  • The type III TGF-beta receptor suppresses breast cancer progression. 
  • The type III transforming growth factor-beta receptor as a novel tumor suppressor gene in prostate cancer. 
  • The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer. 
  • The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells. 
  • Thermal dosimetry characteristics of deep regional heating of non-muscle invasive bladder cancer. 
  • Thin malignant melanomas of the head and neck. 
  • Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition. 
  • Three-dimensional culture systems in cancer research: Focus on tumor spheroid model. 
  • Thrombin-cleaved COOH(-) terminal osteopontin peptide binds with cyclophilin C to CD147 in murine breast cancer cells. 
  • Tissue factor is the receptor for plasminogen type 1 on 1-LN human prostate cancer cells. 
  • Tissue transglutaminase is expressed as a host response to tumor invasion and inhibits tumor growth. 
  • Transhiatal esophagogastrectomy for an isolated ovarian cancer metastasis to the esophagus. 
  • Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma. 
  • Transtubal spread of serous adenocarcinoma of the endometrium: an underrecognized mechanism of metastasis. 
  • Traveling to a High-volume Center is Associated With Improved Survival for Patients With Esophageal Cancer. 
  • Treatment and Outcomes of Women With Large Locally Advanced Breast Cancer. 
  • Treatment of Invasive Brain Tumors Using a Chain-like Nanoparticle. 
  • Trends and appropriateness of perioperative chemotherapy for muscle-invasive bladder cancer. 
  • Tumor genotype determines phenotype and disease-related outcomes in thyroid cancer: a study of 1510 patients. 
  • Tumor invasion of muscular vessels predicts poor prognosis in patients with pancreatic ductal adenocarcinoma who have received neoadjuvant therapy and pancreaticoduodenectomy. 
  • Tumor microenvironment tenascin-C promotes glioblastoma invasion and negatively regulates tumor proliferation. 
  • Tumor volume: an independent predictor of outcome for laryngeal cancer. 
  • Two-dimensional multiplanar and three-dimensional volume-rendered vascular CT in pancreatic carcinoma: interobserver agreement and comparison with standard helical techniques. 
  • Types and duration of symptoms prior to diagnosis of invasive or borderline ovarian tumor. 
  • Tyrosine kinase ETK/BMX is up-regulated in bladder cancer and predicts poor prognosis in patients with cystectomy. 
  • UNC-6 (netrin) orients the invasive membrane of the anchor cell in C. elegans. 
  • Ultrasound: the pulmonologist's new best friend. 
  • Uncinate duct dilation in intraductal papillary mucinous neoplasms of the pancreas: a radiographic finding with potentially increased malignant potential. 
  • Up-regulation of proline-rich tyrosine kinase 2 in non-small cell lung cancer. 
  • Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells. 
  • Urinary-type plasminogen activator receptor/alpha 3 beta 1 integrin signaling, altered gene expression, and oral tumor progression. 
  • Using a continuous transformation of the Breslow thickness for prognosis in cutaneous melanoma. 
  • Uterine Neoplasms. Clinical Practice Guidelines in Oncology. 
  • Utility of Serum Inflammatory Markers for Predicting Microvascular Invasion and Survival for Patients with Hepatocellular Carcinoma. 
  • Utility of a prognostic nomogram designed for gastric cancer in predicting outcome of patients with R0 resected duodenal adenocarcinoma. 
  • Utilization of (111)In-Capromab pendetide SPECT-CT for detecting seminal vesicle invasion with recurrent prostate cancer after primary in situ therapy. 
  • Validating a prognostic scoring system for postmastectomy locoregional recurrence in breast cancer. 
  • Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium. 
  • Validation of an oligo-gene signature for the prognostic stratification of ductal carcinoma in situ (DCIS). 
  • Variation in NF-κB signaling pathways and survival in invasive epithelial ovarian cancer. 
  • Vascular control for resection of suprahepatic intracaval Wilms' tumor: technical considerations. 
  • Vascular invasion is a prognostic indicator in hepatoblastoma. 
  • Vascular surgery collaboration during pancreaticoduodenectomy with vascular reconstruction. 
  • Venous Invasion in Pancreatic Neuroendocrine Tumors Is Independently Associated With Disease-free Survival and Overall Survival. 
  • Villoglandular adenocarcinoma of the cervix: a case report. 
  • Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion. 
  • Wnts and the hallmarks of cancer. 
  • Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27. 
  • mILC-ing the mouse mammary gland: A model for invasive lobular carcinoma. 
• 

  Keywords of People

  • Abbruzzese, James, D. C. I. Distinguished Professor of Medical Oncology, Medicine, Medical Oncology
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Craciunescu, Oana, Professor of Radiation Oncology, Radiation Oncology
  • Esclamado, Ramon Mitra, Richard Hall Chaney, Sr. Distinguished Professor Emeritus of Otolaryngology, Head and Neck Surgery & Communication Sciences
  • Herndon II, James Emmett, Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Hyslop, Terry, Adjunct Professor in the Department of Biostatistics & Bioinformatics, Duke Cancer Institute
  • Jowell, Paul Simon, Professor of Medicine, Medicine, Gastroenterology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute
  • Muh, Carrie Rebecca, Adjunct Assistant Professor in the Department of Neurosurgery, Neurosurgery
  • Palmer, Gregory M., Associate Professor of Radiation Oncology, Radiation Oncology
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering