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Subject Areas on Research
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5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.
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A Circle RNA Regulatory Axis Promotes Lung Squamous Metastasis via CDR1-Mediated Regulation of Golgi Trafficking.
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A Multi-Institutional Study to Evaluate Automated Whole Slide Scoring of Immunohistochemistry for Assessment of Programmed Death-Ligand 1 (PD-L1) Expression in Non-Small Cell Lung Cancer.
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A PRMT5-RNF168-SMURF2 Axis Controls H2AX Proteostasis.
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A Recurrent De Novo Variant in NACC1 Causes a Syndrome Characterized by Infantile Epilepsy, Cataracts, and Profound Developmental Delay.
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A T cell intrinsic role of Id3 in a mouse model for primary Sjogren's syndrome.
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A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity.
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A copula approach for detecting prognostic genes associated with survival outcome in microarray studies.
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A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease.
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A loss-of-function RNA interference screen for molecular targets in cancer.
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A map of human cancer signaling.
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A natural history of melanoma: serial gene expression analysis.
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A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype.
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A novel GALNT3 mutation in a pseudoautosomal dominant form of tumoral calcinosis: evidence that the disorder is autosomal recessive.
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A polymorphism within the promoter of the TGFβ1 gene is associated with radiation sensitivity using an objective radiologic endpoint.
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A proteomic approach for unraveling the oncogenic H-Ras protein networks in NIH/3T3 mouse embryonic fibroblast cells.
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A review of hereditary breast cancer: from screening to risk factor modification.
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A small molecule inhibitor of isoprenylcysteine carboxymethyltransferase induces autophagic cell death in PC3 prostate cancer cells.
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A strategy for the rapid identification of phosphorylation sites in the phosphoproteome.
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A transcriptional repressor of osteopontin expression in the 4T1 murine breast cancer cell line.
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A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells†.
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A truncated isoform of c-Mpl with an essential C-terminal peptide targets the full-length receptor for degradation.
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A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome.
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ATM Paradoxically Promotes Oncogenic Transformation via Transcriptional Reprogramming.
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ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation.
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ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background.
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AURKA amplification, chromosome instability, and centrosome abnormality in human pancreatic carcinoma cells.
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Aberrant FHIT mRNA transcripts are present in malignant and normal haematopoiesis, but absence of FHIT protein is restricted to leukaemia.
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Aberrant expression of cell-cycle regulatory proteins in human mesenchymal neoplasia.
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Abnormal Fhit expression in malignant and premalignant lesions of the cervix.
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Accumulation of p53 protein is frequent in ovarian cancers associated with BRCA1 and BRCA2 germline mutations.
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Accurate identification of proliferative index in melanocytic neoplasms with Melan-A/Ki-67 double stain.
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Acquisition of glutamine synthetase expression in human hepatocarcinogenesis: relation to disease recurrence and possible regulation by ubiquitin-dependent proteolysis.
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Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis.
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Addressing cell-sourcing limitations with gene therapy.
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Agonists of G-Protein-Coupled Odorant Receptors Are Predicted from Chemical Features.
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Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.
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Allele separation facilitates interpretation of potential splicing alterations and genomic rearrangements.
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An Eighteen-Gene Classifier Predicts Locoregional Recurrence in Post-Mastectomy Breast Cancer Patients.
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An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD.
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An in vitro assay procedure to test chemotherapeutic drugs on cells from human solid tumors.
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An inevitable dilemma: prenatal testing for mutations in the BRCA1 breast-ovarian cancer susceptibility gene.
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An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer.
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Analysis of DNA mismatch repair proteins in human medulloblastoma.
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Analysis of novel and recurrent mutations responsible for the tricho-rhino-phalangeal syndromes.
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Analysis of the excision step in human DNA mismatch repair.
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Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/paracrine factors.
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Androgen stimulation of gross cystic disease fluid protein and carcinoembryonic antigen in patients with metastatic breast carcinoma.
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Androgen-independent prostate cancer progression in the TRAMP model.
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Antigen-presenting cells pulsed with unfractionated tumor-derived peptides are potent tumor vaccines.
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Antiinflammatory effects of neoplasms.
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Antiinflammatory proteins associated with human and murine neoplasms.
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Antineoplastic activity of a series of boron analogues of alpha-amino acids.
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Antineoplastic activity of tetrakis-mu-(trimethylamine-boranecarboxylato)-bis (trimethylamine-carboxyborane)dicopper (II) in Ehrlich ascites carcinoma.
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Application of Bayesian modeling of autologous antibody responses against ovarian tumor-associated antigens to cancer detection.
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Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells.
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Assessment of the Clinical Relevance of BRCA2 Missense Variants by Functional and Computational Approaches.
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Assessment of tumor cells in a mouse model of diffuse infiltrative glioma by Raman spectroscopy.
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Association between Tumor Regression Rate and Gene Expression Profile after Iodine 125 Plaque Radiotherapy for Uveal Melanoma.
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Association between XPF polymorphisms and cancer risk: a meta-analysis.
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Association between germline variation in the FHIT gene and prostate cancer in Caucasians and African Americans.
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Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck.
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Association of CARD8 Activating Polymorphism With Bone Erosion in Cholesteatoma Patients.
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Association of CHFR promoter methylation with disease recurrence in locally advanced colon cancer.
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Atypical teratoid/rhabdoid tumor of the central nervous system: a highly malignant tumor of infancy and childhood frequently mistaken for medulloblastoma: a Pediatric Oncology Group study.
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Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor.
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Autocrine stimulation of mas oncogene leads to altered growth control.
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Autologous T cell therapy for MAGE-A4+ solid cancers in HLA-A*02+ patients: a phase 1 trial.
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B-CAM/LU expression and the role of B-CAM/LU activation in binding of low- and high-density red cells to laminin in sickle cell disease.
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BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.
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BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study.
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BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice.
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BP1, a new homeobox gene, is frequently expressed in acute leukemias.
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BRCA1 expression is not directly responsive to estrogen.
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BRCA1 mutations in primary breast and ovarian carcinomas.
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BRCA2 mutations in primary breast and ovarian cancers.
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Baculovirus expression of functional P210 BCR-ABL oncogene product.
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Basal cell adhesion molecule/lutheran protein. The receptor critical for sickle cell adhesion to laminin.
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Bcl10 is not a target for frequent mutation in human carcinomas.
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Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.
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Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models.
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Bone morphogenetic protein-6 is a marker of serous acinar cell differentiation in normal and neoplastic human salivary gland.
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Breakpoints of the t(11;18)(q21;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18.
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CBF, Myb, and Ets binding sites are important for activity of the core I element of the murine retrovirus SL3-3 in T lymphocytes.
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CD30-activation-mediated growth inhibition of anaplastic large-cell lymphoma cell lines: apoptosis or cell-cycle arrest?
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CD40 ligand is essential for generation of specific cytotoxic T cell responses in RNA-pulsed dendritic cell immunotherapy.
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CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping.
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Ca2+-activated Cl- channels at a glance.
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Calcium entry in skeletal muscle.
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Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-Induced Myeloid-Derived Suppressor Cells.
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Cancers of unknown primary origin (CUP) are characterized by chromosomal instability (CIN) compared to metastasis of know origin.
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Capromab Pendetide imaging of prostate cancer.
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Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer.
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Casein kinase 1α-dependent feedback loop controls autophagy in RAS-driven cancers.
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Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo.
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Cell adhesion protein expression in melanocytic matricoma.
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Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response.
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Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response.
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Cell cycle control of BRCA2.
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Cell cycle kinetic effects of tamoxifen on human breast cancer cells. Flow cytometric analyses of DNA content, BrdU labeling, Ki-67, PCNA, and statin expression.
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Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.
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Cellular gene expression in papillomas of the choroid plexus from transgenic mice that express the simian virus 40 large T antigen.
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Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients.
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Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model.
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Checkpoint inhibitors in hematological malignancies.
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Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages.
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Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer.
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Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line.
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Clinico-pathological description of three paediatric medulloblastoma cases with MLL2/3 gene mutations.
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Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity.
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Comparative effectiveness research in cancer genomics and precision medicine: current landscape and future prospects.
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Comparison of animal models for head and neck cancer cachexia.
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Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders.
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Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis.
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Comprehensive analysis of the gene expression profiles in human gastric cancer cell lines.
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Conformal technique dose escalation for prostate cancer: biochemical evidence of improved cancer control with higher doses in patients with pretreatment prostate-specific antigen > or = 10 NG/ML.
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Consortium analysis of 7 candidate SNPs for ovarian cancer.
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Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk.
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Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease.
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Controlling lymphopoiesis with a combinatorial E-protein code.
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Conversion of diploidy to haploidy.
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Costimulation molecule expression and subset distribution of blood dendritic cells in normal children and newly diagnosed pediatric leukemia and lymphoma patients.
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Cotransfection of DC with TLR4 and MART-1 RNA induces MART-1-specific responses.
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Critical factors in basal cell adhesion molecule/lutheran-mediated adhesion to laminin.
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Current national health insurance coverage policies for breast and ovarian cancer prophylactic surgery.
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Cyclooxygenase-2 (COX-2) levels before and after chemotherapy: a study in rectal cancer.
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D6.1, a murine antimelanoma monoclonal antibody from congenitally athymic nude mice immunized with purified melanoma tumor-associated antigen.
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DEPDC1/LET-99 participates in an evolutionarily conserved pathway for anti-tubulin drug-induced apoptosis.
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DNA chain length dependence of formation and dynamics of hMutSalpha.hMutLalpha.heteroduplex complexes.
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DNA hypermethylation within TERT promoter upregulates TERT expression in cancer.
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DNA methylation and obesity in survivors of pediatric acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study.
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Definition of a FoxA1 Cistrome that is crucial for G1 to S-phase cell-cycle transit in castration-resistant prostate cancer.
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Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells.
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Delivery of phosphorodiamidate morpholino antisense oligomers in cancer cells.
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Dendritic cells infected with a vaccinia vector carrying the human gp100 gene simultaneously present multiple specificities and elicit high-affinity T cells reactive to multiple epitopes and restricted by HLA-A2 and -A3.
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Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B.
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Depletion of catalytic and regulatory subunits of protein kinase CK2 by antisense oligonucleotide treatment of neuroblastoma cells.
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Detection and localization of surgically resectable cancers with a multi-analyte blood test.
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Detection of BRCA1 mutations in women with early-onset ovarian cancer by use of the protein truncation test.
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Determination of proliferation index in advanced ovarian cancer using quantitative image analysis.
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Determination of proliferation index with MIB-1 in advanced ovarian cancer using quantitative image analysis.
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Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).
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Development of a radioimmunoassay for fetal antigen 2.
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Differential apoptosis-inducing effect of quercetin and its glycosides in human promyeloleukemic HL-60 cells by alternative activation of the caspase 3 cascade.
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Differential effects of CD30 activation in anaplastic large cell lymphoma and Hodgkin disease cells.
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Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues.
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Differentiation of human T lymphocytes. I. Acquisition of a novel human cell surface protein (p80) during normal intrathymic T cell maturation.
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Distinct roles for c-Myb and core binding factor/polyoma enhancer-binding protein 2 in the assembly and function of a multiprotein complex on the TCR delta enhancer in vivo.
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Distribution and dosimetry of I-123-labeled monoclonal antibody 81C6 in patients with anaplastic glioma.
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Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13.
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Do Largest Basal Tumor Diameter and the American Joint Committee on Cancer's Cancer Staging Influence Prognostication by Gene Expression Profiling in Choroidal Melanoma.
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Do serum biomarkers really measure breast cancer?
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Does prior benign prostate biopsy predict outcome for patients treated with radical perineal prostatectomy?
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Double antibody radioimmunoassay for monitoring metastatic breast cancer.
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Dual role of allele-specific DNA hypermethylation within the TERT promoter in cancer.
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Dying tumor cells stimulate proliferation of living tumor cells via caspase-dependent protein kinase Cδ activation in pancreatic ductal adenocarcinoma.
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Dysregulation of hemostasis by cancer.
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ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells.
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Ectopic expression of interferon regulatory factor-1 promotes human breast cancer cell death and results in reduced expression of survivin.
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Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.
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Effect of inhibitors of proteolytic enzymes on the growth of normal and polyoma transformed BHK cells.
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Effects of JC virus infection on anti-apoptotic protein survivin in progressive multifocal leukoencephalopathy.
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Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival.
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Effects of tumor growth on host defenses.
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Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients.
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Elevated expression of a subset of interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis.
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Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production.
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Endocrine therapy in metastatic breast cancer.
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Endogenous glucocorticoids prevent gastric metaplasia by suppressing spontaneous inflammation.
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Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity.
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Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells.
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Epigenome-wide analysis of long-term air pollution exposure and DNA methylation in monocytes: results from the Multi-Ethnic Study of Atherosclerosis.
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Epithelial cells are an important source of tenascin in normal and malignant human breast tissue.
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Epithelioid Hyalinizing Sarcoma With MGA-NUTM1 Fusion.
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Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.
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Evaluation of expression based markers for the detection of breast cancer cells.
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Evaluation of microsatellite instability, hMLH1 expression and hMLH1 promoter hypermethylation in defining the MSI phenotype of colorectal cancer.
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Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction.
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Exacerbation of Avellino corneal dystrophy after laser in situ keratomileusis.
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Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk.
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Expansion of tumor-T cell pairs from fine needle aspirates of melanoma metastases.
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Expression and prognostic impact of lncRNAs in acute myeloid leukemia.
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Expression of MAGE and GAGE in high-grade brain tumors: a potential target for specific immunotherapy and diagnostic markers.
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Expression of RNA-binding protein IMP3 (KOC) in benign urothelium and urothelial tumors.
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Expression of five selected human mismatch repair genes simultaneously detected in normal and cancer cell lines by a nonradioactive multiplex reverse transcription-polymerase chain reaction.
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Expression of osteocalcin and its transcriptional regulators core-binding factor alpha 1 and MSX2 in osteoid-forming tumours.
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Expression of the protein tyrosine phosphatase, phosphatase of regenerating liver 1, in the outer segments of primate cone photoreceptors.
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Expression of three forms of melanoma growth stimulating activity (MGSA)/gro in human retinal pigment epithelial cells.
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Expression of two type II-like tumor hexokinase RNA transcripts in cancer cell lines.
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Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion.
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FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations.
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FRA1 promotes squamous cell carcinoma growth and metastasis through distinct AKT and c-Jun dependent mechanisms.
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Factor VIII Arg2304 --> His binds to phosphatidylserine and is a functional cofactor in the factor X-ase complex.
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Familial breast-ovarian cancer syndromes: BRCA1 and BRCA2.
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Fibulin-3 is a novel TGF-β pathway inhibitor in the breast cancer microenvironment.
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Fine-needle aspiration diagnosis of psammomatous melanotic schwannoma.
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Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53.
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Fludarabine followed by alemtuzumab consolidation for previously untreated chronic lymphocytic leukemia: final report of Cancer and Leukemia Group B study 19901.
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Fluorescence photobleaching with spatial Fourier analysis: measurement of diffusion in light-scattering media.
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Frequency of MART-1/MelanA and gp100/PMel17-specific T cells in tumor metastases and cultured tumor-infiltrating lymphocytes.
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Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors.
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Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer.
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Functional screen identifies kinases driving prostate cancer visceral and bone metastasis.
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GAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathways.
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Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus.
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Gasdermins: Effectors of Pyroptosis.
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Gastric cancer-molecular and clinical dimensions.
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Gene expression profiles for the prediction of progression-free survival in diffuse large B cell lymphoma: results of a DASL assay.
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Gene expression profiling in melanoma: past results and future potential.
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Gene expression signatures and outcome prediction in mature B-cell malignancies.
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Genetic analysis of sinonasal adenocarcinoma phenotypes: distinct alterations of histogenetic significance.
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Genetic association for renal traits among participants of African ancestry reveals new loci for renal function.
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Genetic interactions between Shox2 and Hox genes during the regional growth and development of the mouse limb.
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Genetic polymorphism at the glutathione S-transferase (GST) P1 locus is a breast cancer risk modifier.
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Genetic polymorphisms of selected DNA repair genes, estrogen and progesterone receptor status, and breast cancer risk.
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Genetic susceptibility testing and prophylactic oophorectomy.
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Genetic variants in the integrin signaling pathway genes predict cutaneous melanoma survival.
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Genetic variants in the vitamin D pathway genes VDBP and RXRA modulate cutaneous melanoma disease-specific survival.
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Genetic variants of SDCCAG8 and MAGI2 in mitosis-related pathway genes are independent predictors of cutaneous melanoma-specific survival.
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Genetic variations in TERT-CLPTM1L genes and risk of squamous cell carcinoma of the head and neck.
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Genome-defined African ancestry is associated with distinct mutations and worse survival in patients with diffuse large B-cell lymphoma.
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Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.
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Genome-wide association studies of the PR interval in African Americans.
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Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia.
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Genome-wide significant risk associations for mucinous ovarian carcinoma.
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Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.
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Genomic FHIT analysis in RER+ and RER- adenocarcinomas of the pancreas.
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Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer.
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Genomic landscapes of breast fibroepithelial tumors.
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Genomic signatures in non-small-cell lung cancer: targeting the targeted therapies.
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Global analysis of protein folding thermodynamics for disease state characterization.
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Global expression analysis of cancer/testis genes in uterine cancers reveals a high incidence of BORIS expression.
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Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways.
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Glucose-regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders.
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Glutamine attenuates lung injury and improves survival after sepsis: role of enhanced heat shock protein expression.
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Glycoconjugates and tumor metastasis.
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Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.
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Gremlin is overexpressed in lung adenocarcinoma and increases cell growth and proliferation in normal lung cells.
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Gα-13 induces CXC motif chemokine ligand 5 expression in prostate cancer cells by transactivating NF-κB.
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HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells.
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HSPB1 gene polymorphisms predict risk of mortality for US patients after radio(chemo)therapy for non-small cell lung cancer.
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HTS-Compatible CometChip Enables Genetic Screening for Modulators of Apoptosis and DNA Double-Strand Break Repair.
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Heavy LIFting: tumor promotion and radioresistance in NPC.
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Hepatic angiomyolipoma and hepatic stellate cells share a similar gene expression profile.
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High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer.
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High incidence of HPV-associated head and neck cancers in FA deficient mice is associated with E7's induction of DNA damage through its inactivation of pocket proteins.
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High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6.
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High-dose, single-agent irinotecan as first-line therapy in the treatment of metastatic colorectal cancer.
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Hormone control and expression of androgen receptor coregulator MAGE-11 in human endometrium during the window of receptivity to embryo implantation.
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Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA.
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Human T-cell leukemia virus type 1 Tax activates cyclin-dependent kinase inhibitor p21/Waf1/Cip1 expression through a p53-independent mechanism: Inhibition of cdk2.
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Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA.
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Human colon cancer cells express multiple glycoprotein ligands for E-selectin.
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Human colorectal carcinomas specifically accumulate Mr 42,000 ubiquitin-conjugated cytokeratin 8 fragments.
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Human dendritic cells, pulsed with either melanoma tumor cell lysates or the gp100 peptide(280-288), induce pairs of T-cell cultures with similar phenotype and lytic activity.
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Human medullary thymocyte p80 antigen and In(Lu)-related p80 antigen reside on the same protein.
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Human mismatch repair: reconstitution of a nick-directed bidirectional reaction.
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Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA.
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Human red cell antigens. V. Expression of In(Lu)-related p80 antigens by recessive-type Lu(a-b-) red cells.
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Human syngeneic intestinal transplantation: evaluation of enterocyte viability with serum levels of intestinal fatty acid binding protein.
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Hurthle cell predominance impacts results of Afirma gene expression classifier and ThyroSeq molecular panel performance in indeterminate thyroid nodules.
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Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer.
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IGF-Binding Proteins, Adiponectin, and Survival in Metastatic Colorectal Cancer: Results From CALGB (Alliance)/SWOG 80405.
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IRTA1 positivity helps identify a MALT-lymphoma-like subset of primary cutaneous marginal zone lymphomas, largely but not exclusively defined by IgM expression.
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Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers.
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Identification of a secreted Mr 95,000 glycoprotein in human melanocytes and melanomas by a melanocyte specific monoclonal antibody.
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Identification of a small molecule that stimulates human β-cell proliferation and insulin secretion, and protects against cytotoxic stress in rat insulinoma cells.
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Identification of a tumor associated antigen that can induce tumor specific cytotoxicity.
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Identification of cellular proteins required for simian virus 40 DNA replication.
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Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate.
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Identification of novel epithelial ovarian cancer loci in women of African ancestry.
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Identification of resting cells by dual-parameter flow cytometry of statin expression and DNA content.
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Identification of the breast cancer susceptibility gene BRCA2.
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Imaging molecular pathways: reporter genes.
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Immune (gamma) interferon production by a murine T cell lymphoma: requirements for macromolecular synthesis and lack of relationship with cell cycle.
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Immune deviation and Fas-mediated deletion limit antitumor activity after multiple dendritic cell vaccinations in mice.
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Immune response of chimpanzee to purified melanoma 250 kilodalton tumor-associated antigen.
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Immune selection after antigen-specific immunotherapy of melanoma.
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Immunophenotype and molecular characterisation of adenocarcinoma of the small intestine.
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Immunotherapy and monoclonal antibody therapies.
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Immunotherapy for malignant melanoma with a tumor cell vaccine.
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Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene.
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Implication of mitochondrial involvement in apoptotic activity of fragile histidine triad gene: application of synchronous luminescence spectroscopy.
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In Situ Proapoptotic Peptide-Generating Rapeseed Protein-Based Nanocomplexes Synergize Chemotherapy for Cathepsin-B Overexpressing Breast Cancer.
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In vivo evaluation of cell mediated immunity against human melanoma.
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In vivo tumor localization using tumor-specific monkey xenoantibody, alloantibody, and murine monoclonal xenoantibody.
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Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression.
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Increasing prostate-specific antigen profile following definitive radiation therapy for localized prostate cancer: clinical observations.
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Induction of lethal experimental allergic encephalomyelitis in nonhuman primates and guinea pigs with human glioblastoma multiforme tissue.
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Induction of p38MAPK and HSP27 phosphorylation in pemphigus patient skin.
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Inhibiting effect of murine double minute-2 oncogene on apoptosis induced by retroviral-mediated wild-type p53.
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Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis.
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Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis.
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Initial testing (stage 1) of the investigational mTOR kinase inhibitor MLN0128 by the pediatric preclinical testing program.
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Initial testing (stage 1) of the notch inhibitor PF-03084014, by the pediatric preclinical testing program.
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Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program.
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Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms.
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Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway.
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Interferon Regulatory Factor 1 (IRF-1) induces p21(WAF1/CIP1) dependent cell cycle arrest and p21(WAF1/CIP1) independent modulation of survivin in cancer cells.
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Interferon-gamma reduces melanosomal antigen expression and recognition of melanoma cells by cytotoxic T cells.
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Intracerebral Flexner-Wintersteiner Rosette-Rich Tumor With Somatic RB1 Mutation: A CNS Embryonal Tumor With Retinoblastic Differentiation.
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Isolation and initial characterization of the BRCA2 promoter.
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JAK2-binding long noncoding RNA promotes breast cancer brain metastasis.
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KIND1 Loss Sensitizes Keratinocytes to UV-Induced Inflammatory Response and DNA Damage.
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KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation.
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Ki-67 expression is a prognostic marker of prostate cancer recurrence after radical prostatectomy.
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Kinetics of TCR use in response to repeated epitope-specific immunization.
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L-selectin binds to P-selectin glycoprotein ligand-1 on leukocytes: interactions between the lectin, epidermal growth factor, and consensus repeat domains of the selectins determine ligand binding specificity.
-
Labeling monoclonal antibodies and F(ab')2 fragments with the alpha-particle-emitting nuclide astatine-211: preservation of immunoreactivity and in vivo localizing capacity.
-
Labeling proteins using aryl iodide acylation agents: influence of meta vs para substitution on in vivo stability.
-
Lack of utility of intestinal fatty acid binding protein levels in predicting intestinal allograft rejection.
-
Lacrimal Gland Tumors.
-
Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using Limited Proteolysis.
-
Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using SILAC-SPROX.
-
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.
-
Laser scanning cytometry evaluation of MART-1, gp100, and HLA-A2 expression in melanoma metastases.
-
Left-Biased Spermatogenic Failure in 129/SvJ Dnd1Ter/+ Mice Correlates with Differences in Vascular Architecture, Oxygen Availability, and Metabolites.
-
Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells.
-
Limitations of tissue microarrays in the evaluation of focal alterations of bcl-2 and p53 in whole mount derived prostate tissues.
-
Localization and quantitation of hexabrachion (tenascin) in skin, embryonic brain, tumors, and plasma.
-
Localization of the VHR phosphatase gene and its analysis as a candidate for BRCA1.
-
Loss of Fhit expression in non-small-cell lung cancer: correlation with molecular genetic abnormalities and clinicopathological features.
-
Loss of KAI1 expression in the progression of colorectal cancer.
-
Loss of heterozygosity of the putative prostate cancer susceptibility gene HPC2/ELAC2 is uncommon in sporadic and familial prostate cancer.
-
Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure.
-
Lung cancer staging: proteomics.
-
Lysophosphatidic acid activates lipogenic pathways and de novo lipid synthesis in ovarian cancer cells.
-
MAGE-1-specific precursor cytotoxic T-lymphocytes present among tumor-infiltrating lymphocytes from a patient with breast cancer: characterization and antigen-specific activation.
-
MEN1 gene mutation analysis of high-grade neuroendocrine lung carcinoma.
-
MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells.
-
MIBG inhibits respiration: potential for radio- and hyperthermic sensitization.
-
MUC1 mucin expression as a marker of progression and metastasis of human colorectal carcinoma.
-
Malignant fibrous histiocytoma of the lateral conjunctiva and anterior orbit.
-
Malignant transformation of the human endometrium is associated with overexpression of lactoferrin messenger RNA and protein.
-
Managing hereditary ovarian cancer risk.
-
Mas oncogene receptor coupling and peptide specificity in Balb 3T3 and vascular smooth muscle cells.
-
Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines.
-
Melanoma, a tumor based on a mutant stem cell?
-
Melastatin expression and prognosis in cutaneous malignant melanoma.
-
Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis.
-
Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell line.
-
Metastatic clear cell renal cell carcinoma: Circulating biomarkers to guide antiangiogenic and immune therapies.
-
Methylthioadenosine phosphorylase and activated insulin-like growth factor-1 receptor/insulin receptor: potential therapeutic targets in chordoma.
-
Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice.
-
Microarray sampling-platform fabrication using bubble-jet technology for a biochip system.
-
Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma.
-
Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas.
-
Mismatch repair-dependent iterative excision at irreparable O6-methylguanine lesions in human nuclear extracts.
-
Modeling cancer progression via pathway dependencies.
-
Modulation of circulating protein biomarkers following TRC105 (anti-endoglin antibody) treatment in patients with advanced cancer.
-
Modulation of ligand binding affinity of the adipocyte lipid-binding protein by selective mutation. Analysis in vitro and in situ.
-
Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78.
-
Molecular Profiling to Determine Clonality of Serial Magnetic Resonance Imaging/Ultrasound Fusion Biopsies from Men on Active Surveillance for Low-Risk Prostate Cancer.
-
Molecular analysis of the JAZF1-JJAZ1 gene fusion by RT-PCR and fluorescence in situ hybridization in endometrial stromal neoplasms.
-
Molecular analysis-based treatment strategies for the management of non-small cell lung cancer.
-
Molecular biologic substaging of stage I NSCLC through immunohistochemistry performed on formalin-fixed, paraffin-embedded tissue.
-
Molecular interactions of B-CAM (basal-cell adhesion molecule) and laminin in epithelial skin cancer.
-
Molecular pathways and therapeutic targets in lung cancer.
-
Monoclonal antibodies for brain tumour treatment.
-
Monoclonal antibody against human T cell leukemia virus p19 defines a human thymic epithelial antigen acquired during ontogeny.
-
Morphologic features of 115 lymphomas of the orbit and ocular adnexa categorized according to the World Health Organization classification: are marginal zone lymphomas in the orbit mucosa-associated lymphoid tissue-type lymphomas?
-
Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex.
-
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma.
-
Multiple assay characterization of murine monoclonal antimelanoma antibodies.
-
Multiple hereditary exostoses (MHE): elucidating the pathogenesis of a rare skeletal disorder through interdisciplinary research.
-
Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer.
-
Murine dendritic cells transfected with human GP100 elicit both antigen-specific CD8(+) and CD4(+) T-cell responses and are more effective than DNA vaccines at generating anti-tumor immunity.
-
Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias.
-
Mutational processes in cancer preferentially affect binding of particular transcription factors.
-
Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases.
-
Mutations of the E-cadherin gene in human gynecologic cancers.
-
Mutations of the Wilms tumor 1 gene (WT1) in older patients with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.
-
N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells.
-
Neutrophil gelatinase-associated lipocalin in normal and neoplastic human tissues. Cell type-specific pattern of expression.
-
Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy.
-
No evidence for linkage of liability to autism to HOXA1 in a sample from the CPEA network.
-
Novel epinephrine and cyclic AMP-mediated activation of BCAM/Lu-dependent sickle (SS) RBC adhesion.
-
Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.
-
Novel therapeutic approaches to advanced prostate cancer.
-
Oncogene pathway activation in mammary tumors dictates FDG-PET uptake.
-
Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway.
-
Oncogenic Signaling Pathways and Pathway-Based Therapeutic Biomarkers in Lymphoid Malignancies.
-
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23.
-
Osteopontin regulates ubiquitin-dependent degradation of Stat1 in murine mammary epithelial tumor cells.
-
Overexpressed BAG3 is a potential therapeutic target in chronic lymphocytic leukemia.
-
Overexpression of human carcinoma-associated antigen in urothelial carcinoma of the bladder.
-
Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions.
-
PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer.
-
PD-1 blockade inhibits osteoclast formation and murine bone cancer pain.
-
PD-L1 expression is low in large B-cell lymphoma with MYC or double-hit translocation.
-
PSCA polymorphisms and gastric cancer susceptibility in an eastern Chinese population.
-
PSGR, a novel prostate-specific gene with homology to a G protein-coupled receptor, is overexpressed in prostate cancer.
-
PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics.
-
Pancreatic cyst fluid protein expression profiling for discriminating between serous cystadenoma and intraductal papillary mucinous neoplasm.
-
Parc-ing p53 in the cytoplasm.
-
Patterns of somatic mutation in human cancer genomes.
-
PenPC: A two-step approach to estimate the skeletons of high-dimensional directed acyclic graphs.
-
Pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, combined with azacitidine in patients with AML.
-
Pharmacokinetics and tumor localization of 131I-labeled anti-tenascin monoclonal antibody 81C6 in patients with gliomas and other intracranial malignancies.
-
Phase 1 study in patients with metastatic melanoma of immunization with dendritic cells presenting epitopes derived from the melanoma-associated antigens MART-1 and gp100.
-
Phase 2 study of the safety and efficacy of umbralisib in patients with CLL who are intolerant to BTK or PI3Kδ inhibitor therapy.
-
Phenotypic expansion of KMT2D-related disorder: Beyond Kabuki syndrome.
-
Phosphorylation of microtubule-associated proteins by protein kinase CK2 in neuritogenesis.
-
Plectin is a regulator of prostate cancer growth and metastasis.
-
Polymorphisms in the ERCC5 gene and risk of esophageal squamous cell carcinoma (ESCC) in Eastern Chinese populations.
-
Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation.
-
Poorly differentiated carcinoma and poorly differentiated adenocarcinoma of unknown origin: favorable subsets of patients with unknown-primary carcinoma?
-
Postremission therapy with low-dose interleukin 2 with or without intermediate pulse dose interleukin 2 therapy is well tolerated in elderly patients with acute myeloid leukemia: Cancer and Leukemia Group B study 9420.
-
Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines.
-
Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody.
-
Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis.
-
Preparation of apoptotic tumor cells with replication-incompetent HSV augments the efficacy of dendritic cell vaccines.
-
Prevention of brefeldin A-induced resistance to teniposide by the proteasome inhibitor MG-132: involvement of NF-kappaB activation in drug resistance.
-
Primary mucinous carcinoma of the eyelid: a clinicopathologic and immunohistochemical study of 4 cases and an update on recurrence rates.
-
Primate-specific melanoma antigen-A11 regulates isoform-specific human progesterone receptor-B transactivation.
-
Prognostic applications of the epidermal growth factor receptor and its ligand, transforming growth factor-alpha.
-
Prognostic features and treatment outcome in locoregionally advanced nasopharyngeal carcinoma following concurrent chemotherapy and radiotherapy.
-
Prognostic value of cell-cycle markers in ocular adnexal lymphoma: an assessment of 230 cases.
-
Proliferative activity at colonic anastomoses as determined by statin. A nonproliferation-specific nuclear protein.
-
Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry.
-
Proteome-Wide Characterization of Phosphorylation-Induced Conformational Changes in Breast Cancer.
-
Proteomic analysis of calcium/calmodulin-dependent protein kinase I and IV in vitro substrates reveals distinct catalytic preferences.
-
Proteomic analysis of stage I endometrial cancer tissue: identification of proteins associated with oxidative processes and inflammation.
-
Proteomics in prostate cancer.
-
Quantitation of response to therapy in patients with metastatic breast carcinoma by serial analysis of plasma gross cystic disease fluid protein and carcinoembryonic antigen.
-
Quantitative expression profile of PSGR in prostate cancer.
-
RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation.
-
Radical prostatectomy lowers plasma vascular endothelial growth factor levels in patients with prostate cancer.
-
Radioprotection of lungs by amifostine is associated with reduction in profibrogenic cytokine activity.
-
Radiosensitization of chemotherapy-refractory, locally advanced or locally recurrent breast cancer with trastuzumab: a phase II trial.
-
Rapid degradation of puromycyl peptides in hepatoma cells and reticulocytes.
-
Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function.
-
Recombinant human endostatin could eliminate the pro-angiogenesis priority of SP cells sorted from non-small cell lung cancer cells.
-
Rectal cancer: the influence of tumor proliferation on response to preoperative irradiation.
-
Reduced expression of hMLH1 and hGTBP/hMSH6: a risk factor for head and neck cancer.
-
Reduced expression of hMSH2 and hMLH1 and risk of prostate cancer: a case-control study.
-
Reduced expression of mismatch repair genes in colorectal cancer patients in Egypt.
-
Reduced expression of mismatch repair genes measured by multiplex reverse transcription-polymerase chain reaction in human gliomas.
-
Regulation and localization of HSP70 and HSP25 in the kidney of rats undergoing long-term administration of angiotensin II.
-
Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background.
-
Regulatory network motifs and hotspots of cancer genes in a mammalian cellular signalling network.
-
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.
-
Ribosomal RACK1:Protein Kinase C βII Modulates Intramolecular Interactions between Unstructured Regions of Eukaryotic Initiation Factor 4G (eIF4G) That Control eIF4E and eIF3 Binding.
-
Ribosomal RACK1:Protein Kinase C βII Phosphorylates Eukaryotic Initiation Factor 4G1 at S1093 To Modulate Cap-Dependent and -Independent Translation Initiation.
-
Role of Rap1 in promoting sickle red blood cell adhesion to laminin via BCAM/LU.
-
Roles of Alternative RNA Splicing of the Bif-1 Gene by SRRM4 During the Development of Treatment-induced Neuroendocrine Prostate Cancer.
-
Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype.
-
SET alpha and SET beta mRNA isoforms in chronic lymphocytic leukaemia.
-
SOCE and STIM1 signaling in the heart: Timing and location matter.
-
SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype.
-
STAT3-enhancing germline mutations contribute to tumor-extrinsic immune evasion.
-
STT3A, C1orf24, TFF3: putative markers for characterization of follicular thyroid neoplasms from fine-needle aspirates.
-
SYT-SSX1 (synovial sarcoma translocated) regulates PIASy ligase activity to cause overexpression of NCOA3 protein.
-
Sclerosing hemangioma of lung: A close cytologic mimicker of pulmonary adenocarcinoma.
-
Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB.
-
Selective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neurons.
-
Sequential delivery of maturation stimuli increases human dendritic cell IL-12 production and enhances tumor antigen-specific immunogenicity.
-
Sequential phase II Southwest Oncology Group studies (S0112 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with ciclosporin, in older patients with previously untreated acute myeloid leukaemia.
-
Serum protein expression predicts recurrence in patients with early-stage lung cancer after resection.
-
Shared heritability and functional enrichment across six solid cancers.
-
Short-term kinetics of tumor antigen expression in response to vaccination.
-
Side population cells in human cancers.
-
Significance of Co-expression of Epidermal Growth Factor Receptor and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiotherapy: An Analysis of NRG Oncology RTOG 9811.
-
Simultaneous detection of the tumor suppressor FHIT gene and protein using the multi-functional biochip.
-
Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance).
-
Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin.
-
So-called massive retinal gliosis: A critical review and reappraisal.
-
Soluble factor in normal tissues that stimulates high-molecular-weight sialoglycoprotein production by human colon carcinoma cells.
-
Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability.
-
Some properties of a DNA-unwinding protein unique to lymphocytes from chronic lymphocytic leukemia.
-
Stage-specific expression of B cell translocation gene 1 in rat testis.
-
Status of activation of circulating vaccine-elicited CD8+ T cells.
-
Stemming Lung Disease?
-
Strategic Therapeutic Targeting to Overcome Venetoclax Resistance in Aggressive B-cell Lymphomas.
-
Structural requirements for high affinity ligand binding by estrogen receptors: a comparative analysis of truncated and full length estrogen receptors expressed in bacteria, yeast, and mammalian cells.
-
Subungual leiomyoma in the left thumb of a 16-year-old female.
-
Superantigen enhanced protection against a weak tumor-specific melanoma antigen: implications for prophylactic vaccination against cancer.
-
Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice.
-
Surface proteins of a transitional carcinoma cell line (KS-31E).
-
Surgical treatment of malignant esophageal tumors in PUMC Hospital.
-
Survival analysis of presumptive prognostic markers among oligodendrogliomas.
-
Survivin DNA vaccine generated specific antitumor effects in pancreatic carcinoma and lymphoma mouse models.
-
Sustained in vivo regression of Dunning H rat prostate cancers treated with combinations of androgen ablation and Trk tyrosine kinase inhibitors, CEP-751 (KT-6587) or CEP-701 (KT-5555).
-
Synergistic cofactor function of factor V and protein S to activated protein C in the inactivation of the factor VIIIa - factor IXa complex -- species specific interactions of components of the protein C anticoagulant system.
-
Synergistic effects of multiple natural products in pancreatic cancer cells.
-
Synergy between tumor immunotherapy and antiangiogenic therapy.
-
Systematic identification of signaling pathways with potential to confer anticancer drug resistance.
-
Systemic inflammatory response syndrome after human syngeneic intestinal transplantation: evidence for disruption of enterocyte barrier function.
-
Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer.
-
T cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10.
-
T(H)2 bias: Mina tips the balance.
-
T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes.
-
T-cell lymphoblastic lymphoma involving the ocular adnexa: report of two cases and review of the current literature.
-
TGF-beta inhibits the in vitro induction of lymphokine-activated killing activity.
-
Targeted next generation sequencing identifies clinically actionable mutations in patients with melanoma.
-
Targeting BCL-2 with venetoclax and dexamethasone in patients with relapsed/refractory t(11;14) multiple myeloma.
-
Targeting Id1 and Id3 inhibits peritoneal metastasis of gastric cancer.
-
Targeting the Wnt-Regulatory Protein CTNNBIP1 by microRNA-214 Enhances the Stemness and Self-Renewal of Cancer Stem-Like Cells in Lung Adenocarcinomas.
-
Targeting the local tumor microenvironment with vaccinia virus expressing B7.1 for the treatment of melanoma.
-
Telomerase activity in normal leukocytes and in hematologic malignancies.
-
Template for reporting results of biomarker testing of specimens from patients with carcinoma of the colon and rectum.
-
Tenascin: an extracellular matrix protein prominent in specialized embryonic tissues and tumors.
-
The Abl family kinases: mechanisms of regulation and signaling.
-
The C-terminal domain of viral IAP associated factor (cVIAF) is a structural homologue of phosducin: resonance assignments and secondary structure of the C-terminal domain of VIAF.
-
The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1.
-
The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms.
-
The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.
-
The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma.
-
The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer.
-
The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming.
-
The Role of Biliary Carcinoembryonic Antigen-Related Cellular Adhesion Molecule 6 (CEACAM6) as a Biomarker in Cholangiocarcinoma.
-
The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.
-
The Utility of Perilipin in Liposarcomas: PLIN1 Differentiates Round Cell Liposarcoma From Other Round Cell Sarcomas.
-
The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages.
-
The betagamma subunit of heterotrimeric G proteins interacts with RACK1 and two other WD repeat proteins.
-
The detection of telomerase activity in patients with adenocarcinoma of the pancreas by fine needle aspiration.
-
The effect of protein nutrition on host and tumor metabolism.
-
The genetic attributable risk of breast and ovarian cancer.
-
The genetic landscape of mutations in Burkitt lymphoma.
-
The genetic landscape of the childhood cancer medulloblastoma.
-
The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells.
-
The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome.
-
The hedgehog pathway in nonalcoholic fatty liver disease.
-
The human myoepithelial cell displays a multifaceted anti-angiogenic phenotype.
-
The regulation of ferroptosis by MESH1 through the activation of the integrative stress response.
-
The role of MTJ-1 in cell surface translocation of GRP78, a receptor for alpha 2-macroglobulin-dependent signaling.
-
The role of N-acetylation polymorphisms in smoking-associated bladder cancer: evidence of a gene-gene-exposure three-way interaction.
-
The role of hPMS1 and hPMS2 in predisposing to colorectal cancer.
-
The role of protein phosphorylation in therapy resistance and disease progression in chronic myelogenous leukemia.
-
The synthesis and anti-neoplastic activity of N2-isobutyryl-2'-deoxyguanosine-N7-cyanoborane derivatives.
-
The therapeutic effects of SET/I2PP2A inhibitors on canine melanoma.
-
The treatment of colorectal carcinoma: standard chemotherapy and beyond.
-
The tumor biology of melanoma nodal metastases.
-
Thermodynamic profiling of conformationally constrained cyclic ligands for the PDZ domain.
-
Threshold levels of gene expression of the melanoma antigen gp100 correlate with tumor cell recognition by cytotoxic T lymphocytes.
-
Topotecan, a topoisomerase I inhibitor, is active in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia.
-
Toward clinical understanding of aristolochic acid upper-tract urothelial carcinoma.
-
Transfection of RNA encoding tumor antigens following maturation of dendritic cells leads to prolonged presentation of antigen and the generation of high-affinity tumor-reactive cytotoxic T lymphocytes.
-
Transforming growth factor-beta differentially inhibits epithelial ovarian carcinoma cells from primary and metastatic isolates without up-regulation of p21WAF1.
-
Transport rather than diffusion-dependent route for nitric oxide gas activity in alveolar epithelium.
-
Treatment of intracranial human glioma xenografts with 131I-labeled anti-tenascin monoclonal antibody 81C6.
-
TrkB inhibition by GNF-4256 slows growth and enhances chemotherapeutic efficacy in neuroblastoma xenografts.
-
Trophinin is a potent prognostic marker of ovarian cancer involved in platinum sensitivity.
-
Tumor marker expression is predictive of survival in patients with esophageal cancer.
-
Tumor proliferation in rectal cancer following preoperative irradiation.
-
Tumour extracellular vesicle-derived Complement Factor H promotes tumorigenesis and metastasis by inhibiting complement-dependent cytotoxicity of tumour cells.
-
Twenty-year survival in glioblastoma: a case report and molecular profile.
-
Unique proteins defined by monoclonal antibodies specific for human melanoma. Some potential clinical applications.
-
Use of tissue microarray and automated quantitative analysis for screening and validation of potential biomarkers in mantle cell lymphoma.
-
Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials.
-
Vaccine therapy in non-small-cell lung cancer.
-
Variability in platelet procoagulant activity in healthy volunteers.
-
Vascular leukocytes: a population with angiogenic and immunossuppressive properties highly represented in ovarian cancer.
-
Whole Genomic Copy Number Alterations in Circulating Tumor Cells from Men with Abiraterone or Enzalutamide-Resistant Metastatic Castration-Resistant Prostate Cancer.
-
Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion.
-
XPD/ERCC2 EXON 8 Polymorphisms: rarity and lack of significance in risk of squamous cell carcinoma of the head and neck.
-
Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP.
-
Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27.
-
[Chicken RNA tumor viruses: a model for virus-induced carcinogenesis].
-
[Surgical treatment of malignant esophageal tumors in PUMC Hospital].
-
c-Jun promotes whereas JunB inhibits epidermal neoplasia.
-
c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor delta enhancer.
-
miR-203, a tumor suppressor frequently down-regulated by promoter hypermethylation in rhabdomyosarcoma.
-
miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia.
-
p38-MAPK induced dephosphorylation of alpha-tropomyosin is associated with depression of myocardial sarcomeric tension and ATPase activity.
-
p53 and MDM2 immunostaining in pulmonary blastomas and bronchogenic carcinomas.
-
p53 and mdm-2 expression in malignant melanoma: an immunocytochemical study of expression of p53, mdm-2, and markers of cell proliferation in primary versus metastatic tumors.
-
p53-dependent induction of heat shock protein 27 (HSP27) expression.
-
β-Arrestin2 mediates the initiation and progression of myeloid leukemia.
-
Keywords of People
-
-
Abbruzzese, James,
D. C. I. Distinguished Professor of Medical Oncology,
Medicine, Medical Oncology
-
Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
-
Cianciolo, George James,
Associate Professor Emeritus of Pathology,
Pathology
-
Ciofani, Maria,
Associate Professor of Immunology,
Cell Biology
-
Erickson, Harold Paul,
Professor Emeritus of Cell Biology,
Cell Biology
-
Ferreira, Paulo Alexandre,
Associate Professor in Ophthalmology,
Pathology
-
Hilton, Matthew James,
Associate Professor in Orthopaedic Surgery,
Cell Biology
-
Hogan, Brigid L. M.,
Research Professor of Cell Biology,
Cell Biology
-
Krangel, Michael S.,
George Barth Geller Distinguished Professor of Immunology,
Immunology
-
McLendon, Roger Edwin,
Professor of Pathology,
Pathology
-
Meyer, Joel,
Associate Professor of Environmental Genomics in the Division of Environmental Sciences and Policy,
Nicholas Institute-Energy Initiative
-
Moorman, Patricia Gripka,
Professor Emeritus in Family Medicine and Community Health,
Duke Cancer Institute
-
Sullivan, Daniel Carl,
Professor Emeritus of Radiology,
Radiology
-
Weinhold, Kent James,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery,
Immunology
-
Woodward, Julie Ann,
Professor of Ophthalmology,
Dermatology
-
Zafar, Syed Yousuf,
Adjunct Professor in the Department of Medicine,
Duke Science & Society
-
Zhong, Xiaoping,
Professor of Pediatrics,
Immunology