Neoplasm Transplantation

• 

  Subject Areas on Research

  • 125I-labeled anti-epidermal growth factor receptor-vIII single-chain Fv exhibits specific and high-level targeting of glioma xenografts. 
  • 211At radiocolloid therapy: further observations and comparison with radiocolloids of 32P, 165Dy, and 90Y. 
  • 5α-Reductase inhibition coupled with short off cycles increases survival in the LNCaP xenograft prostate tumor model on intermittent androgen deprivation therapy. 
  • A genetically modified allogeneic cellular vaccine generates MHC class I-restricted cytotoxic responses against tumor-associated antigens and protects against CNS tumors in vivo. 
  • A local hyperthermia treatment which enhances antibody uptake in a glioma xenograft model does not affect tumour interstitial fluid pressure. 
  • A novel in vitro assay of tumor-initiating cells in xenograft prostate tumors. 
  • A novel murine model of human renal cell carcinoma spinal metastasis. 
  • A novel rodent mammary window of orthotopic breast cancer for intravital microscopy. 
  • A novel toll-like receptor 9 agonist cooperates with trastuzumab in trastuzumab-resistant breast tumors through multiple mechanisms of action. 
  • A novel, clinically relevant animal model of metastatic pancreatic adenocarcinoma biology and therapy. 
  • A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models. 
  • A peptide inhibitor derived from p55PIK phosphatidylinositol 3-kinase regulatory subunit: a novel cancer therapy. 
  • A rapidly dividing human medulloblastoma cell line (D283 MED) expresses all three neurofilament subunits. 
  • A serially transplantable human giant cell glioblastoma that maintains a near-haploid stem line. 
  • ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling. 
  • AJAP1 is dysregulated at an early stage of gliomagenesis and suppresses invasion through cytoskeleton reorganization. 
  • Acidic stress promotes a glioma stem cell phenotype. 
  • Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression. 
  • Activation of RalA is critical for Ras-induced tumorigenesis of human cells. 
  • Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts. 
  • Activity of VNP40101M (Cloretazine) in the treatment of CNS tumor xenografts in athymic mice. 
  • Activity of intrathecal 4-hydroperoxycyclophosphamide in a nude rat model of human neoplastic meningitis. 
  • Activity of temozolomide in the treatment of central nervous system tumor xenografts. 
  • Acyl derivatives of demethylpenclomedine, an antitumor-active, non-neurotoxic metabolites of penclomedine. 
  • Adenovirus-mediated antisense urokinase-type plasminogen activator receptor gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines. 
  • Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy. 
  • Adjuvant chemotherapy for colorectal hepatic metastases: role of route of administration and timing. 
  • Adoptively transferred ex vivo expanded gammadelta-T cells mediate in vivo antitumor activity in preclinical mouse models of breast cancer. 
  • Allotransplantation of insulinoma into the testis of diabetic rats. 
  • Altered growth of a human neuroendocrine carcinoma line after transfection of a major histocompatibility complex class I gene. 
  • Alternatively spliced human tissue factor promotes tumor growth and angiogenesis in a pancreatic cancer tumor model. 
  • Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression. 
  • Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts. 
  • Amplification of the c-myc gene in human medulloblastoma cell lines and xenografts. 
  • An analysis of the uncertainty and bias in DCE-MRI measurements using the spoiled gradient-recalled echo pulse sequence. 
  • An improved method of preparing Schmidt-Ruppin Rous sarcoma virus for brain tumor induction in mammals. 
  • An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation. 
  • Analysis of the relationship between stage of differentiation and NK/LAK susceptibility of colon carcinoma cells. 
  • Anaplastic human gliomas grown in athymic mice. Morphology and glial fibrillary acidic protein expression. 
  • Androgen receptor down-regulation in prostate cancer with phosphorodiamidate morpholino antisense oligomers. 
  • Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice. 
  • Angiotensin receptor signaling and prostate tumor growth in mice. 
  • Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee. 
  • Anti-tubulin drugs conjugated to anti-ErbB antibodies selectively radiosensitize. 
  • Antiangiogenic treatment with three thrombospondin-1 type 1 repeats versus gemcitabine in an orthotopic human pancreatic cancer model. 
  • Antigens of human pancreatic adenocarcinoma cells defined by murine monoclonal antibodies. 
  • Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models. 
  • Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer. 
  • Assessment of the protective effect of amifostine on radiation-induced pulmonary toxicity. 
  • Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment. 
  • BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis. 
  • BW2258U89: a GRP receptor antagonist which inhibits small cell lung cancer growth. 
  • Bevacizumab, irinotecan, temozolomide, tyrosine kinase inhibition, and MEK inhibition are effective against pleomorphic xanthoastrocytoma regardless of V600E status. 
  • Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models. 
  • Biodistribution of O6-benzylguanine and its effectiveness against human brain tumor xenografts when given in polyethylene glycol or cremophor-EL. 
  • Biology of gliomas: potential clinical implications of glioma cellular heterogeneity. 
  • Biology of hepatocellular neoplasia in the mouse. I. Histogenesis of safrole-induced hepatocellular carcinoma. 
  • Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma. 
  • Bone marrow-derived mesenchymal stem cells undergo JCV T-antigen mediated transformation and generate tumors with neuroectodermal characteristics. 
  • Boosting high-intensity focused ultrasound-induced anti-tumor immunity using a sparse-scan strategy that can more effectively promote dendritic cell maturation. 
  • Brain cancer stem cells display preferential sensitivity to Akt inhibition. 
  • Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa). 
  • Bromodeoxyuridine-mediated radiosensitization in human glioma: the effect of concentration, duration, and fluoropyrimidine modulation. 
  • Busulfan therapy of central nervous system xenografts in athymic mice. 
  • C-type virus particles in human urogenital tumours after heterotransplantation into nude mice. 
  • CAR T Cells Targeting Podoplanin Reduce Orthotopic Glioblastomas in Mouse Brains. 
  • CHML promotes liver cancer metastasis by facilitating Rab14 recycle. 
  • Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer. 
  • Casein kinase 1α-dependent feedback loop controls autophagy in RAS-driven cancers. 
  • Caspase 3 promotes surviving melanoma tumor cell growth after cytotoxic therapy. 
  • Cell cycle-independent death of prostate adenocarcinoma is induced by the trk tyrosine kinase inhibitor CEP-751 (KT6587). 
  • Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors. 
  • Characterization of new gangliosides of the lactotetraose series in murine xenografts of a human glioma cell line. 
  • Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts. 
  • Chemodosimetry of in vivo tumor liposomal drug concentration using MRI. 
  • Chemotherapy and radiation therapy of human medulloblastoma in athymic nude mice. 
  • Chemotherapy of subcutaneous and intracranial human medulloblastoma xenografts in athymic nude mice. 
  • Chimeric anti-tenascin antibody 81C6: increased tumor localization compared with its murine parent. 
  • Chromosomal composition of malignant human gliomas through serial subcutaneous transplantation in athymic mice. 
  • Cl- and K+ transport in human biliary cell lines. 
  • Colonoscopic injection for murine solid cecal cancer model. 
  • Combination chemotherapy with vincristine, cyclophosphamide, and prednisone producing long-term remission of a transplanted canine lymphoma. 
  • Combination testing of cediranib (AZD2171) against childhood cancer models by the pediatric preclinical testing program. 
  • Compact point-detection fluorescence spectroscopy system for quantifying intrinsic fluorescence redox ratio in brain cancer diagnostics. 
  • Comparative localization of glioma-reactive monoclonal antibodies in vivo in an athymic mouse human glioma xenograft model. 
  • Comparing in vivo pump-probe and multiphoton fluorescence microscopy of melanoma and pigmented lesions. 
  • Comparison of [18 F]fluorocholine and [18 F]fluorodeoxyglucose for positron emission tomography of androgen dependent and androgen independent prostate cancer. 
  • Comparison of animal models for head and neck cancer cachexia. 
  • Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents. 
  • Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition. 
  • Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes. 
  • Creation of human tumour cells with defined genetic elements. 
  • Cross-reacting antigens on L5178Y cells which serve as targets for cytotoxic T-lymphocyte lysis during establishment of the tumor dormant state. 
  • Cross-talk between Schwann cells and neuroblasts influences the biology of neuroblastoma xenografts. 
  • Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes. 
  • Cytosine methylation and suppression of O6-methylguanine-DNA methyltransferase expression in human rhabdomyosarcoma cell lines and xenografts. 
  • Cytosolic TMEM88 promotes invasion and metastasis in lung cancer cells by binding DVLS. 
  • Defining regional infusion treatment strategies for extremity melanoma: comparative analysis of melphalan and temozolomide as regional chemotherapeutic agents. 
  • Delivery-corrected imaging of fluorescently-labeled glucose reveals distinct metabolic phenotypes in murine breast cancer. 
  • Dendritic cells pulsed with a tumor-specific peptide induce long-lasting immunity and are effective against murine intracerebral melanoma. 
  • Detection of metastatic tumors in nude mice: brief communication. 
  • Development and validation of a method for using breast core needle biopsies for gene expression microarray analyses. 
  • Development of a high-efficiency method for gene marking of Dunning prostate cancer cell lines with the enzyme beta-galactosidase. 
  • Differential adhesion of rat colon carcinoma cells to fibronectin in relation to their tumorigenicity. 
  • Differential effects of parenteral nutrition on tumor growth and erythrocyte polyamine levels in the rat. 
  • Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts. 
  • Dipyridamole-cisplatin potentiation: enhanced in vivo cytotoxicity in xenograft models of human testicular and bladder cancers. 
  • Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. 
  • Direct in vivo measurement of targeted binding in a human tumor xenograft. 
  • Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells. 
  • Dll4 Inhibition plus Aflibercept Markedly Reduces Ovarian Tumor Growth. 
  • Donor cell leukemia in umbilical cord blood transplant patients: a case study and literature review highlighting the importance of molecular engraftment analysis. 
  • Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells. 
  • Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents. 
  • Dynamic contrast-enhanced MR microscopy identifies regions of therapeutic response in a preclinical model of colorectal adenocarcinoma. 
  • EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss. 
  • EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma. 
  • ELF3 is a repressor of androgen receptor action in prostate cancer cells. 
  • ELR+ CXC chemokines and oncogenic Ras-mediated tumorigenesis. 
  • EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma. 
  • Effect of aerobic exercise on tumor physiology in an animal model of human breast cancer. 
  • Effect of host microenvironment on the microcirculation of human colon adenocarcinoma. 
  • Effect of isocaloric low fat diet on prostate cancer xenograft progression in a hormone deprivation model. 
  • Effective treatment of experimental DU-145 prostate cancers with targeted cytotoxic somatostatin analog AN-238. 
  • Effects of 10-hydroxycamptothecin, delivered from locally injectable poly(lactide-co-glycolide) microspheres, in a murine human oral squamous cell carcinoma regression model. 
  • Effects of bradykinin on the hemodynamics of tumor and granulating normal tissue microvasculature. 
  • Effects of cell damage and glycosaminoglycan degradation on available extravascular space of different dextrans in a rat fibrosarcoma. 
  • Effects of glutathione or polyamine depletion on in vivo thermosensitization. 
  • Effects of hyperthermia and irradiation on the growth of mouse melanoma tumors following immunotherapy. 
  • Effects of murine cytomegalovirus infection on the immune response to a tumor allograft. 
  • Effects of pentobarbital anesthesia on the energy metabolism of murine tumors studied by in vivo 31P nuclear magnetic resonance spectroscopy. 
  • Effects of primary and recurrent sacral chordoma on the motor and nociceptive function of hindlimbs in rats: an orthotopic spine model. 
  • Effects of the calcium channel blocker flunarizine on the hemodynamics and oxygenation of tumor microvasculature. 
  • Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts. 
  • Effects of therapy on the 1H NMR spectrum of a human glioma line. 
  • Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT(®) nanoparticle formulation against non-small-cell lung cancer brain metastases. 
  • Efficacy of antisense morpholino oligomer targeted to c-myc in prostate cancer xenograft murine model and a Phase I safety study in humans. 
  • Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release. 
  • Efficacy of multiple administrations of a recombinant adenovirus expressing wild-type p53 in an immune-competent mouse tumor model. 
  • Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow. 
  • Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model. 
  • Enhanced delivery of a monoclonal antibody F(ab')2 fragment to subcutaneous human glioma xenografts using local hyperthermia. 
  • Enhanced melphalan cytotoxicity following buthionine sulfoximine-mediated glutathione depletion in a human medulloblastoma xenograft in athymic mice. 
  • Enhanced optical imaging of rat gliomas and tumor margins. 
  • Enhanced tumour uptake and in vitro radiotoxicity of no-carrier-added [131I]meta-iodobenzylguanidine: implications for the targeted radiotherapy of neuroblastoma. 
  • Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents. 
  • Enhancement of melphalan activity by inhibition of DNA polymerase-alpha and DNA polymerase-beta. 
  • Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme. 
  • Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. 
  • Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells. 
  • Epigenetic silencing of Kruppel like factor-3 increases expression of pro-metastatic miR-182. 
  • Erythropoietin receptor contributes to melanoma cell survival in vivo. 
  • Establishment and characterization of a new human prostatic carcinoma cell line (DuPro-1). 
  • Establishment and characterization of the human medulloblastoma cell line and transplantable xenograft D283 Med. 
  • Establishment of a melphalan-resistant rhabdomyosarcoma xenograft with cross-resistance to vincristine and enhanced sensitivity following buthionine sulfoximine-mediated glutathione depletion. 
  • Estrogen stimulation and tamoxifen inhibition of leiomyoma cell growth in vitro and in vivo. 
  • Evaluation of meta-[211At]astatobenzylguanidine in an athymic mouse human neuroblastoma xenograft model. 
  • Evaluation of new anticancer agents against human pancreatic carcinomas in nude mice. 
  • Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system. 
  • Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents. 
  • Experimental chemotherapy of human medulloblastoma with classical alkylators. 
  • Expression of reg/PSP, a pancreatic exocrine gene: relationship to changes in islet beta-cell mass. 
  • Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells. 
  • FOXA2 is a sensitive and specific marker for small cell neuroendocrine carcinoma of the prostate. 
  • Factors regulating islet regeneration in the post-insulinoma NEDH rat. 
  • Fc-mOX40L fusion protein produces complete remission and enhanced survival in 2 murine tumor models. 
  • Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma. 
  • Fluorescence ratio imaging of interstitial pH in solid tumours: effect of glucose on spatial and temporal gradients. 
  • Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation. 
  • Fluorine-18-labeled monoclonal antibody fragments: a potential approach for combining radioimmunoscintigraphy and positron emission tomography. 
  • Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle in rats. 
  • Function in athymic nude mice of parathyroid heterografts from patients with primary hyperparathyroidism and secondary hyperparathyroidism. 
  • Functional and morphologic changes associated with insulinoma transplantation into diabetic rats. 
  • Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer. 
  • Functional expression of sodium-glucose transporters in cancer. 
  • G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity. 
  • Ganglioside mapping of a human medulloblastoma xenograft. 
  • Gangliosides in the human glioma cell line U-118 MG grown in culture or as xenografts in nude rats. 
  • Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma. 
  • Generation of autologous tumor-specific cytotoxic T-cells using HLA-A region matched allogeneic melanoma. 
  • Generation of orthotopic and heterotopic human pancreatic cancer xenografts in immunodeficient mice. 
  • Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity. 
  • Genetic modeling of Ras-induced human rhabdomyosarcoma. 
  • Genetic modeling of human rhabdomyosarcoma. 
  • Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. 
  • Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia. 
  • Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth. 
  • Gradient hydrogels for screening stiffness effects on patient-derived glioblastoma xenograft cellfates in 3D. 
  • Growth and chemotherapeutic response in athymic mice of tumors arising from human glioma-derived cell lines. 
  • Growth inhibition of a human lung adenocarcinoma cell line by genetic complementation with chromosome 11. 
  • Growth, morphology, and serial transplantation of anaplastic human gliomas in athymic mice. 
  • Guidelines for the welfare and use of animals in cancer research. 
  • Hedgehog and Notch signaling regulate self-renewal of undifferentiated pleomorphic sarcomas. 
  • Her2/neu signaling blockade improves tumor oxygenation in a multifactorial fashion in Her2/neu+ tumors. 
  • Heterogeneity in the hormonal responsiveness of clones derived from the 13762NF rat mammary tumor. 
  • Heterogeneity in tumor microvascular response to radiation. 
  • Heterotransplantation of a human prostatic adenocarcinoma cell line in nude mice. 
  • Heterotransplantation of human craniopharyngiomas in athymic "nude" mice. 
  • Host regulation of MOPC 104E plasmacytoma after reduction of tumor burden by total body irradiation. 
  • How heterogeneous are gliomas? 
  • Human brain tumor xenografts. 
  • Human melanoma growth in the peritoneal cavity of the athymic mouse--a model for in vivo study of cell-mediated immunity. 
  • Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. 
  • Human recombinant erythropoietin significantly improves tumor oxygenation independent of its effects on hemoglobin. 
  • Human xenograft-nude mouse model of adoptive immunotherapy with human melanoma-specific cytotoxic T-cells. 
  • Humoral antibody response and tumor transplantation resistance elicited by fetal tissues in mice. 
  • Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size. 
  • Hyperthermia-induced enhancement of melphalan activity against a melphalan-resistant human rhabdomyosarcoma xenograft. 
  • Hypertonic saline-augmented radiofrequency ablation of the VX-2 tumor implanted in the rabbit kidney: a short-term survival pilot study. 
  • Hypothesis: when is a seminoma not a seminoma? 
  • Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. 
  • IL26, a Noncanonical Mediator of DNA Inflammatory Stimulation, Promotes TNBC Engraftment and Progression in Association with Neutrophils. 
  • IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity. 
  • Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. 
  • Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma. 
  • Identification of nitrosourea-resistant human rhabdomyosarcomas by in situ immunostaining of O6-methylguanine-DNA methyltransferase. 
  • Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer. 
  • Imaging taxane-induced tumor apoptosis using PEGylated, 111In-labeled annexin V. 
  • Immunocompetent murine model of cancer cachexia for head and neck squamous cell carcinoma. 
  • Immunologic control of the ascites of murine adenocarcinoma 755. I. Protection with syngeneic immune serum or lymphoid cells. 
  • Immunological consequences of transplanting rat insulinomas. 
  • Immunological memory induced by genetically transduced tumor cells. 
  • Immunotherapy with vaccines combining MHC class II/CD80+ tumor cells with interleukin-12 reduces established metastatic disease and stimulates immune effectors and monokine induced by interferon gamma. 
  • Impaired proliferation and tumorigenicity induced by CCAAT/enhancer-binding protein. 
  • Improved therapeutic efficacy of a monoclonal antibody radioiodinated using N-succinimidyl-3-(tri-n-butylstannyl)benzoate. 
  • Improving DNA double-strand repair inhibitor KU55933 therapeutic index in cancer radiotherapy using nanoparticle drug delivery. 
  • In vitro and in vivo antitumor effect of the anti-CD26 monoclonal antibody 1F7 on human CD30+ anaplastic large cell T-cell lymphoma Karpas 299. 
  • In vitro versus in vivo correlations of chemosensitivity of human medulloblastoma. 
  • In vivo and in vitro binding of iodinated monoclonal antibody A2B5 to RIN insulinoma cells. 
  • In vivo and in vitro propagation of intraductal papillary mucinous neoplasms. 
  • In vivo evaluation of cell mediated immunity against human melanoma. 
  • In vivo imaging of intracranial human glioma xenografts comparing specific with nonspecific radiolabeled monoclonal antibodies. 
  • In vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma. 
  • In vivo monitoring of tissue pharmacokinetics of liposome/drug using MRI: illustration of targeted delivery. 
  • In vivo regulation of hTERT expression and telomerase activity by androgen. 
  • In vivo tumor localization using tumor-specific monkey xenoantibody, alloantibody, and murine monoclonal xenoantibody. 
  • Increased melphalan activity in intracranial human medulloblastoma and glioma xenografts following buthionine sulfoximine-mediated glutathione depletion. 
  • Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice. 
  • Influence of circulating antigen on blood pool activity of a radioiodinated monoclonal antibody. 
  • Influence of mouse hepatitis virus on the growth of human melanoma in the peritoneal cavity of the athymic mouse. 
  • Influence of total parenteral nutrition on tumor growth and polyamine biosynthesis of fibrosarcoma-bearing rats after induced cachexia. 
  • Influence of tumour size on human prostate tumour metastasis in athymic nude mice. 
  • Inhibition of PC-3 human androgen-independent prostate cancer and its metastases by cytotoxic somatostatin analogue AN-238. 
  • Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis. 
  • Inhibition of growth of MDA-MB-468 estrogen-independent human breast carcinoma by bombesin/gastrin-releasing peptide antagonists RC-3095 and RC-3940-II. 
  • Inhibition of growth of OV-1063 human epithelial ovarian cancers and c- jun and c- fos oncogene expression by bombesin antagonists. 
  • Inhibition of haematogenous metastasis of colon cancer in mice by a selective COX-2 inhibitor, JTE-522. 
  • Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. 
  • Inhibition of telomerase is related to the life span and tumorigenicity of human prostate cancer cells. 
  • Inhibition of the growth of human melanoma metastases in nude mice by melanoma-specific murine monoclonal antibody. 
  • Inhibition of the growth of human melanoma xenografts in nude mice by human tumor-specific cytotoxic T-cells. 
  • Initial testing (stage 1) of LCL161, a SMAC mimetic, by the Pediatric Preclinical Testing Program. 
  • Initial testing (stage 1) of temozolomide by the pediatric preclinical testing program. 
  • Initial testing (stage 1) of the cyclin dependent kinase inhibitor SCH 727965 (dinaciclib) by the pediatric preclinical testing program. 
  • Initial testing (stage 1) of the phosphatidylinositol 3' kinase inhibitor, SAR245408 (XL147) by the pediatric preclinical testing program. 
  • Initial testing of the hypoxia-activated prodrug PR-104 by the pediatric preclinical testing program. 
  • Intact nitric oxide synthase II gene is required for interferon-beta-mediated suppression of growth and metastasis of pancreatic adenocarcinoma. 
  • Intergeneric poliovirus recombinants for the treatment of malignant glioma. 
  • Interlaboratory variation in oxygen tension measurement by Eppendorf "Histograph" and comparison with hypoxic marker. 
  • Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis. 
  • Interstitial hydraulic conductivity in a fibrosarcoma. 
  • Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. 
  • Intracerebral growth of a human glioma tumor line in athymic mice and treatment with procarbazine, 1,3-bis(2-chloroethyl)-1-nitrosourea, aziridinylbenzoquinone, and cis-platinum. 
  • Intracerebral transplantation of a human glioma line in immunosuppressed rats. 
  • Intraportal injection of monoclonal antibody in nude mice bearing hepatic metastases. 
  • Intravascular location of breast cancer cells after spontaneous metastasis to the lung. 
  • Intravenous adenosine selectively increases blood flow to xenotransplanted intracerebral gliomas. 
  • Invasiveness of human glioma cell lines in vitro: relation to tumorigenicity in athymic mice. 
  • Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer. 
  • Isolation of a transplantable cell line induced by the MC29 avian leukosis virus. 
  • L-buthionine-sulfoximine-mediated radiosensitization in experimental interstitial radiotherapy of intracerebral D-54 MG glioma xenografts in athymic mice. 
  • LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers. 
  • Label-free oxygen-metabolic photoacoustic microscopy in vivo. 
  • Labeling monoclonal antibodies and F(ab')2 fragments with the alpha-particle-emitting nuclide astatine-211: preservation of immunoreactivity and in vivo localizing capacity. 
  • Lactotetraose series ganglioside 3',6'-isoLD1 in tumors of central nervous and other systems in vitro and in vivo. 
  • Laryngeal transplantation in the setting of cancer: a rat model. 
  • Leukaemia hijacks a neural mechanism to invade the central nervous system. 
  • Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. 
  • Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens. 
  • Local hyperthermia improves uptake of a chimeric monoclonal antibody in a subcutaneous xenograft model. 
  • Local secretion of IL-12 augments the therapeutic impact of dendritic cell-tumor cell fusion vaccination. 
  • Localisation of [131I]MIBG in nude mice bearing SK-N-SH human neuroblastoma xenografts: effect of specific activity. 
  • Localization of fluorine-18-labeled Mel-14 monoclonal antibody F(ab')2 fragment in a subcutaneous xenograft model. 
  • Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 derived miniRNA as a novel plasma-based biomarker for diagnosing prostate cancer. 
  • Lysyl oxidase is essential for hypoxia-induced metastasis. 
  • M-HIFU inhibits tumor growth, suppresses STAT3 activity and enhances tumor specific immunity in a transplant tumor model of prostate cancer. 
  • Macrophage migratory dysfunction in cancer. A mechanism for subversion of surveillance. 
  • Medulloblastoma: tumor biological and clinical perspectives. 
  • Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy. 
  • Melphalan transport, glutathione levels, and glutathione-S-transferase activity in human medulloblastoma. 
  • Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment. 
  • Methylation subtypes and large-scale epigenetic alterations in gastric cancer. 
  • Methylator resistance mediated by mismatch repair deficiency in a glioblastoma multiforme xenograft. 
  • Mibefradil, a novel therapy for glioblastoma multiforme: cell cycle synchronization and interlaced therapy in a murine model. 
  • Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation. 
  • Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. 
  • Microvascular permeability of albumin, vascular surface area, and vascular volume measured in human adenocarcinoma LS174T using dorsal chamber in SCID mice. 
  • Modulation of cyclophosphamide activity by O6-alkylguanine-DNA alkyltransferase. 
  • Modulation of murine breast tumor vascularity, hypoxia and chemotherapeutic response by exercise. 
  • Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas. 
  • Monoclonal antibody localization in subcutaneous and intracranial human glioma xenografts: paired-label and imaging analysis. 
  • Morphological and biochemical properties of a new human breast cancer cell line. 
  • Mouse models of metastatic pancreatic adenocarcinoma. 
  • Mouse-INtraDuctal (MIND): an in vivo model for studying the underlying mechanisms of DCIS malignancy. 
  • Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice. 
  • Murine dendritic cells transfected with human GP100 elicit both antigen-specific CD8(+) and CD4(+) T-cell responses and are more effective than DNA vaccines at generating anti-tumor immunity. 
  • Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting. 
  • NFκB-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice. 
  • Nanoparticle delivery of chemosensitizers improve chemotherapy efficacy without incurring additional toxicity. 
  • Nanoshell-mediated photothermal therapy improves survival in a murine glioma model. 
  • Near-infrared optical imaging of integrin alphavbeta3 in human tumor xenografts. 
  • Neuroblastoma grafts are noninvasively removed within mouse neocortex by selective laser activation of intracellular photolytic chromophore. 
  • New murine cell line derived from a spontaneous lung tumor induces paraneoplastic syndromes. 
  • Noninvasive measurement of microvascular and interstitial oxygen profiles in a human tumor in SCID mice. 
  • Noninvasive visualization of retinoblastoma growth and metastasis via bioluminescence imaging. 
  • Nonlinear dependence of hydraulic conductivity on tissue deformation during intratumoral infusion. 
  • Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer. 
  • O6-alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts. 
  • O6-benzylguanine-mediated enhancement of chemotherapy. 
  • O6-benzylguanine-mediated enhancement of nitrosourea activity in Mer- central nervous system tumor xenografts--implications for clinical trials. 
  • Occurrence of lacto series gangliosides 3'-isoLM1 and 3',6'-isoLD1 in human gliomas in vitro and in vivo. 
  • Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors. 
  • Osteopontin has a protective role in prostate tumor development in mice. 
  • Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis. 
  • Osteopontin regulates epithelial mesenchymal transition-associated growth of hepatocellular cancer in a mouse xenograft model. 
  • Overexpression of the MT1 melatonin receptor in MCF-7 human breast cancer cells inhibits mammary tumor formation in nude mice. 
  • Overview of genetically engineered mouse models of colorectal carcinoma to enable translational biology and drug development. 
  • Oxygen distributions within R3230Ac tumors growing in dorsal flap window chambers in rats. 
  • PC3 is a cell line characteristic of prostatic small cell carcinoma. 
  • PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation. 
  • PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma. 
  • Partial suppression of anchorage-independent growth and tumorigenicity in immunodeficient mice by transfection of the H-2 class I gene H-2Ld into a human colon cancer cell line (HCT). 
  • Perfusion of single tumor microvessels: application to vascular permeability measurement. 
  • Pharmacokinetics and radiation dosimetry of 18F-fluorocholine. 
  • Pharmacokinetics of a radioiodinated monoclonal antibody F(ab')2 fragment in a xenograft model with circulating antigen. 
  • Phenotypic analysis of four human medulloblastoma cell lines and transplantable xenografts. 
  • Phenotypic and genotypic analysis of a human medulloblastoma cell line and transplantable xenograft (D341 Med) demonstrating amplification of c-myc. 
  • Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas. 
  • Pigment epithelium-derived factor stimulates tumor macrophage recruitment and is downregulated by the prostate tumor microenvironment. 
  • Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor. 
  • Plectin is a regulator of prostate cancer growth and metastasis. 
  • Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells. 
  • Positive therapeutic interaction between thiopurines and alkylating drugs in human glioma xenografts. 
  • Positively charged templates for labeling internalizing antibodies: comparison of N-succinimidyl 5-iodo-3-pyridinecarboxylate and the D-amino acid peptide KRYRR. 
  • Precision cancer immunotherapy: optimizing dendritic cell-based strategies to induce tumor antigen-specific T-cell responses against individual patient tumors. 
  • Preferential extravasation and accumulation of liposomal vincristine in tumor comparing to normal tissue enhances antitumor activity. 
  • Primary hyperparathyroidism: a new experimental animal model. 
  • Proceedings: Immunologic similarities between fetal cell antigens and tumor cell antigens in guinea pigs. 
  • Production and characterization of two ependymoma xenografts. 
  • Production and characterization of two human glioma xenograft-localizing monoclonal antibodies. 
  • Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models. 
  • Properties of prostatic cultures transformed by SV40. 
  • Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay. 
  • Protein Arginine Methyltransferase 5 Promotes pICln-Dependent Androgen Receptor Transcription in Castration-Resistant Prostate Cancer. 
  • Protein C inhibitor (plasminogen activator inhibitor-3) expression in the CWR22 prostate cancer xenograft. 
  • Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration. 
  • Quantification of longitudinal tissue pO2 gradients in window chamber tumours: impact on tumour hypoxia. 
  • Quantitative proton spectroscopy and histology of a canine brain tumor model. 
  • RGS-GAIP-interacting protein controls breast cancer progression. 
  • RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression. 
  • Radioimmunotherapy of breast cancer xenografts with monoclonal antibody ICR12 against c-erbB2 p185: comparison of iodogen and N-succinimidyl 4-methyl-3-(tri-n-butylstannyl)benzoate radioiodination methods. 
  • Radioiodinated B6.2 monoclonal antibody: further characterization of a potential radiopharmaceutical for the identification of breast tumors. 
  • Radioiodination of a monoclonal antibody using N-succinimidyl 5-iodo-3-pyridinecarboxylate. 
  • Radioiodination via D-amino acid peptide enhances cellular retention and tumor xenograft targeting of an internalizing anti-epidermal growth factor receptor variant III monoclonal antibody. 
  • Radioiodine and 211At-labeled guanidinomethyl halobenzoyl octreotate conjugates: potential peptide radiotherapeutics for somatostatin receptor-positive cancers. 
  • Radiolocalization of human mammary tumors in athymic mice by a monoclonal antibody. 
  • Radiolocalization of human pancreatic tumors in athymic mice by monoclonal antibody DU-PAN 1. 
  • Rationale for immunotoxin therapy of metastatic prostate carcinoma formatted as a multi-stage delivery system. 
  • Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression. 
  • Recombinant human tumor necrosis factor alone and with chemotherapeutic agents. Effect on nude mouse-supported human bladder cancer heterografts. 
  • Recombinant oncolytic poliovirus eliminates glioma in vivo without genetic adaptation to a pathogenic phenotype. 
  • Reduction of artifacts in T2 -weighted PROPELLER in high-field preclinical imaging. 
  • Regional localization of a glioma-associated antigen defined by monoclonal antibody 81C6 in vivo: kinetics and implications for diagnosis and therapy. 
  • Regional measurements of blood flow in experimental RG-2 rat gliomas. 
  • Regional measurements of blood-to-tissue transport in experimental RG-2 rat gliomas. 
  • Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1. 
  • Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development. 
  • Relationship between binding affinity, retention and sensitivity of human rhabdomyosarcoma xenografts to Vinca alkaloids. 
  • Relationship of in vitro morphologic and growth characteristics of established human glioma-derived cell lines to their tumorigenicity in athymic nude mice. 
  • Renal carcinosarcoma. Ultrastructure and transplantation into athymic mice. 
  • Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR. 
  • Reversing the Warburg effect as a treatment for glioblastoma. 
  • Review of methods used to study oxygen transport at the microcirculatory level. 
  • Rodent model of reproductive tract leiomyomata. Clinical and pathological features. 
  • Rodent model of reproductive tract leiomyomata. Establishment and characterization of tumor-derived cell lines. 
  • Role of TGF-β receptor III localization in polarity and breast cancer progression. 
  • Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions. 
  • SV40-transformed hamster prostatic tissue: a model of human prostatic malignancy. 
  • Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic Cells. 
  • Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts. 
  • Schedule-dependent activity of temozolomide plus CPT-11 against a human central nervous system tumor-derived xenograft. 
  • Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer. 
  • Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion. 
  • Sequential immunotherapy by vaccination with GM-CSF-expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors. 
  • Serological response of non-human primates to human melanoma disialoganglioside GD3. 
  • Side population cells in human cancers. 
  • Side population cells isolated from mesenchymal neoplasms have tumor initiating potential. 
  • Simultaneous measurements of blood flow and blood-to-tissue transport in xenotransplanted medulloblastomas. 
  • Soft-tissue sarcomas: detection of metabolic heterogeneity with P-31 MR spectroscopy. 
  • Specific and high-level targeting of radiolabeled octreotide analogues to human medulloblastoma xenografts. 
  • Specific chromosomal abnormalities characterize four established cell lines derived from malignant human gliomas. 
  • Specific imaging of human brain tumor xenografts utilizing radiolabelled monoclonal antibodies (MAbs). 
  • Spontaneous metastasis of cells of the human prostate carcinoma cell line PC-3 in athymic nude mice. 
  • Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism. 
  • Stromelysin-3 suppresses tumor cell apoptosis in a murine model. 
  • Structural adaptation and heterogeneity of normal and tumor microvascular networks. 
  • Structure and specific antigens of avian leukosis viruses. 
  • Studies of tumor metabolism--II. Mössbauer spectroscopy of 57Co-bleomycin. 
  • Substituting ornithine for arginine in total parenteral nutrition eliminates enhanced tumor growth. 
  • Suppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapy. 
  • Suppression of pancreatic tumor progression by systemic delivery of a pancreatic-cancer-specific promoter driven Bik mutant. 
  • Suppression of tumor formation in vivo by expression of the JE gene in malignant cells. 
  • Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. 
  • Suppression of tumorigenicity of A549 lung adenocarcinoma cells by human chromosomes 3 and 11 introduced via microcell-mediated chromosome transfer. 
  • Sustained in vivo regression of Dunning H rat prostate cancers treated with combinations of androgen ablation and Trk tyrosine kinase inhibitors, CEP-751 (KT-6587) or CEP-701 (KT-5555). 
  • Swainsonine protects both murine and human haematopoietic systems from chemotherapeutic toxicity. 
  • Syndecan-1 facilitates breast cancer metastasis to the brain. 
  • Synergistic interactions between cyclophosphamide or melphalan and VP-16 in a human rhabdomyosarcoma xenograft. 
  • Synthesis and evaluation of glycosylated octreotate analogues labeled with radioiodine and 211At via a tin precursor. 
  • Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells. 
  • Systemic dissemination of viral vectors during intratumoral injection. 
  • T helper 2-dominant antilymphoma immune response is associated with fatal outcome. 
  • Targeted alpha-particle therapy of microscopic disease: Providing a further rationale for clinical investigation. 
  • Targeted drug delivery to C6 glioma by transferrin-coupled liposomes. 
  • Targeting N-cadherin enhances antitumor activity of cytotoxic therapies in melanoma treatment. 
  • Targeting N-cadherin increases vascular permeability and differentially activates AKT in melanoma. 
  • Targeting UDP-α-D-glucose 6-dehydrogenase inhibits glioblastoma growth and migration. 
  • Targeting cell surface F1F0 ATP synthase in cancer therapy. 
  • Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. 
  • Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome. 
  • Temozolomide delivered by intracerebral microinfusion is safe and efficacious against malignant gliomas in rats. 
  • The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. 
  • The effect of an amino acid-lowering diet on the rate of melphalan entry into brain and xenotransplanted glioma. 
  • The effect of carbohydrate restriction on prostate cancer tumor growth in a castrate mouse xenograft model. 
  • The effects of hyperoxic and hypercarbic gases on tumour blood flow. 
  • The effects of local hyperthermia on the catabolism of a radioiodinated chimeric monoclonal antibody. 
  • The localisation of radiolabelled murine monoclonal antibody 81C6 and its Fab fragment in human glioma xenografts in athymic mice. 
  • The mechanisms by which hyperbaric oxygen and carbogen improve tumour oxygenation. 
  • The radiation dose-response relationship in a human glioma xenograft and an evaluation of the influence of glutathione depletion by buthionine sulfoximine. 
  • The role of WNT10B in normal prostate gland development and prostate cancer. 
  • The synthetic phosphagen cyclocreatine phosphate inhibits the growth of a broad spectrum of solid tumors. 
  • The therapeutic impact of dipyridamole: chemopotentiation of the cytotoxic combination 5-fluorouracil/cisplatin in an animal model of human bladder cancer. 
  • Therapeutic activity of 7-[(2-trimethylsilyl)ethyl)]-20 (S)-camptothecin against central nervous system tumor-derived xenografts in athymic mice. 
  • Therapeutic activity of the topoisomerase I inhibitor J-107088 [6-N-(1-hydroxymethyla-2-hydroxyl) ethylamino-12,13-dihydro-13-(beta-D-glucopyranosyl) -5H-indolo[2,3-a]-pyrrolo[3,4-c]-carbazole-5,7(6H)-dione]] against pediatric and adult central nervous system tumor xenografts. 
  • Therapeutic analysis of in vitro and in vivo brain tumor models. 
  • Therapeutic analysis of melphalan-resistant human rhabdomyosarcoma xenograft TE-671 MR. 
  • Therapeutic efficacy of antiglioma mesenchymal extracellular matrix 131I-radiolabeled murine monoclonal antibody in a human glioma xenograft model. 
  • Therapeutic efficacy of vinorelbine against pediatric and adult central nervous system tumors. 
  • Therapeutic profile of the human glioma line D-54 MG in athymic mice. 
  • Tissue distribution and radiation dosimetry of astatine-211-labeled chimeric 81C6, an alpha-particle-emitting immunoconjugate. 
  • Tobacco Carcinogen-Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer. 
  • Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway. 
  • Transduction of human melanoma cells with interleukin-2 gene reduces tumorigenicity and enhances host antitumor immunity: a nude mouse model. 
  • Transplantation of insulinoma into the diabetic Syrian hamster. 
  • Transplantation of rat insulinoma allografts with cyclosporin A. 
  • Treatment of central nervous system xenografts with camptothecins. 
  • Treatment of five subcutaneous human glioma tumor lines in athymic mice with carmustine, procarbazine, and mithramycin. 
  • Treatment of human glioma and medulloblastoma tumor lines in athymic mice with diaziquone and diaziquone-based drug combinations. 
  • Treatment of human melanoma hepatic metastases in nude mice with human cytotoxic T lymphocytes. 
  • Treatment of intracranial human glioma xenografts with 131I-labeled anti-tenascin monoclonal antibody 81C6. 
  • Treatment of neoplastic meningitis with intrathecal temozolomide. 
  • Treatment of subcutaneous and intracranial brain tumor xenografts with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea. 
  • Trefoil factor 1 acts to suppress senescence induced by oncogene activation during the cellular transformation process. 
  • Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells. 
  • Tumor Endothelial Cells with Distinct Patterns of TGFβ-Driven Endothelial-to-Mesenchymal Transition. 
  • Tumor blood flow: I. Blood flow in transplantable tumors during growth. 
  • Tumor microvascular permeability is a key determinant for antivascular effects of doxorubicin encapsulated in a temperature sensitive liposome. 
  • Tumor resistance in rats immunized to fetal tissues. 
  • Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment. 
  • Tumor-specific anti-epidermal growth factor receptor variant III monoclonal antibodies: use of the tyramine-cellobiose radioiodination method enhances cellular retention and uptake in tumor xenografts. 
  • Tumorigenic cell culture lines from a spontaneous VM/Dk murine astrocytoma (SMA). 
  • Tumour-dormant states established with L5178Y lymphoma cells in immunised syngeneic murine hosts. 
  • Type III TGF-β receptor downregulation generates an immunotolerant tumor microenvironment. 
  • Tyrosine phosphorylation of the human glutathione S-transferase P1 by epidermal growth factor receptor. 
  • UBE2N Promotes Melanoma Growth via MEK/FRA1/SOX10 Signaling. 
  • Urinary-type plasminogen activator receptor/alpha 3 beta 1 integrin signaling, altered gene expression, and oral tumor progression. 
  • Use of in vivo bioluminescence imaging to predict hepatic tumor burden in mice. 
  • Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. 
  • Viral infection-homograft interactions in a murine model. 
  • Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish. 
  • Vitamin E succinate decreases lung cancer tumor growth in mice. 
  • Wilms' tumor growth is suppressed by antiangiogenic pigment epithelium-derived factor in a xenograft model. 
  • Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27. 
  • [A novel model for visualization of tumor cell-induced angiogenesis in vivo]. 
  • [Experimental studies on human lung cancer gene-therapy with HSV-TK/GCV system]. 
  • [Inhibitation of tumor angiogenesis, growth and metastasis by blocking VEGF paracrine pathway]. 
  • [Insulin producing cells as therapy in diabetes mellitus]. 
  • [Intraportal injection of specific monoclonal antibody in nude mice with liver metastasis]. 
  • c-MYC antisense phosphosphorodiamidate morpholino oligomer inhibits lung metastasis in a murine tumor model. 
  • c-Myc is required for maintenance of glioma cancer stem cells. 
  • lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. 
  • miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β. 
  • miR-33a promotes glioma-initiating cell self-renewal via PKA and NOTCH pathways. 
  • αB-crystallin: a novel regulator of breast cancer metastasis to the brain. 
• 

  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Charles, Hal Cecil, Adjunct Associate Professor in the Department of Radiology, Radiology
  • Hanks, Brent A., Associate Professor of Medicine, Pharmacology & Cancer Biology
  • Lee, Walter T, Professor of Head and Neck Surgery & Communication Sciences, Radiation Oncology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Palmer, Gregory M., Associate Professor of Radiation Oncology, Radiation Oncology
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
  • Sullivan, Daniel Carl, Professor Emeritus of Radiology, Radiology
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Integrative Immunobiology