Nephrotic Syndrome

• 

  Subject Areas on Research

  • A new locus for familial FSGS on chromosome 2p. 
  • A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome. 
  • A systematic approach to mapping recessive disease genes in individuals from outbred populations. 
  • ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption. 
  • AKI in Children Hospitalized with Nephrotic Syndrome. 
  • ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling. 
  • An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome. 
  • Antecedent renal disease and the outcome of pregnancy. 
  • Appearance of immune complex glomerulonephritis following the onset of type I diabetes mellitus in a child. 
  • Assessing responsiveness over time of the PROMIS® pediatric symptom and function measures in cancer, nephrotic syndrome, and sickle cell disease. 
  • COQ2 nephropathy: a newly described inherited mitochondriopathy with primary renal involvement. 
  • COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. 
  • Case for the panel Nephrotic syndrome with fibrillary and lipid deposits. 
  • Collapsing glomerulopathy in 19 patients with systemic lupus erythematosus or lupus-like disease. 
  • Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's): An ARChiVe Cohort Study. 
  • Complete Remission in the Nephrotic Syndrome Study Network. 
  • Deaths in childhood nephrotic syndrome in Ibadan, Nigeria. 
  • Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach. 
  • Digital pathology evaluation in the multicenter Nephrotic Syndrome Study Network (NEPTUNE). 
  • Evolving concepts of the intrarenal renin-angiotensin system in health and disease: contributions of molecular biology. 
  • Focal segmental glomerulosclerosis associated with nephrotic syndrome in cholesterol atheroembolism: clinicopathological correlations. 
  • Gaining the PROMIS perspective from children with nephrotic syndrome: a Midwest pediatric nephrology consortium study. 
  • Genetic testing in nephrotic syndrome--challenges and opportunities. 
  • Genetics of childhood steroid-sensitive nephrotic syndrome. 
  • Global glomerulosclerosis with nephrotic syndrome; the clinical importance of age adjustment. 
  • Glomerulopathies with fibrillary deposits. 
  • HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome. 
  • Histopathological diagnosis and outcome of paediatric nephrotic syndrome. 
  • Idiopathic collapsing focal segmental glomerulosclerosis: a clinicopathologic study. 
  • Inaccuracy of the Schwartz formula in estimating glomerular filtration rate in Nigerian children. 
  • Increased steroid responsiveness of young children with nephrotic syndrome in Nigeria. 
  • Inducible podocyte injury and proteinuria in transgenic zebrafish. 
  • Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects. 
  • KANK deficiency leads to podocyte dysfunction and nephrotic syndrome. 
  • Lithium-induced nephrotic syndrome. 
  • Looking at renal failure upside down. 
  • Losing their footing: Rac1 signaling causes podocyte detachment and FSGS. 
  • Loss of Epithelial Membrane Protein 2 Aggravates Podocyte Injury via Upregulation of Caveolin-1. 
  • Low prevalence of NPHS2 mutations in African American children with steroid-resistant nephrotic syndrome. 
  • Management of childhood onset nephrotic syndrome. 
  • Management patterns of childhood-onset nephrotic syndrome. 
  • Mutational analysis of NPHS2 and WT1 in frequently relapsing and steroid-dependent nephrotic syndrome. 
  • Mutations in EMP2 cause childhood-onset nephrotic syndrome. 
  • Mycotic aneurysm of the thoracoabdominal aorta in a child with end-stage renal disease. 
  • Nephrotic syndrome complicating alpha-glucosidase replacement therapy for Pompe disease. 
  • Nephrotic syndrome in the first year of life: two thirds of cases are caused by mutations in 4 genes (NPHS1, NPHS2, WT1, and LAMB2). 
  • Pediatric biopsy of a single native kidney. 
  • Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible. 
  • Potential donor-recipient MYH9 genotype interactions in posttransplant nephrotic syndrome after pediatric kidney transplantation. 
  • Renin-angiotensin-aldosterone system in nephrotic syndrome. 
  • Reproducibility and Feasibility of Strategies for Morphologic Assessment of Renal Biopsies Using the Nephrotic Syndrome Study Network Digital Pathology Scoring System. 
  • Resolution of primary amyloidosis during chemotherapy. Studies in a patient with nephrotic syndrome. 
  • Responsiveness of the PROMIS® measures to changes in disease status among pediatric nephrotic syndrome patients: a Midwest pediatric nephrology consortium study. 
  • Role of urine and serum protein electrophoresis in evaluation of nephrotic-range proteinuria. 
  • Specific podocin mutations correlate with age of onset in steroid-resistant nephrotic syndrome. 
  • Staphylococcus aureus pneumonia, hyponatremia, hypertension, proteinuria, and hematuria in a 14-year-old boy. 
  • System for integrated adherence monitoring: real-time non-adherence risk assessment in pediatric kidney transplantation. 
  • The Application of Digital Pathology to Improve Accuracy in Glomerular Enumeration in Renal Biopsies. 
  • The impact of disease duration on quality of life in children with nephrotic syndrome: a Midwest Pediatric Nephrology Consortium study. 
  • The nephrotic syndrome in congenital syphilis: an immunopathy. 
  • The predominance of membranoproliferative glomerulonephritis in childhood nephrotic syndrome in Ibadan, Nigeria. 
  • Thirteen novel NPHS1 mutations in a large cohort of children with congenital nephrotic syndrome. 
  • Translating genetic findings in hereditary nephrotic syndrome: the missing loops. 
  • Treatment outcome of late steroid-resistant nephrotic syndrome: a study by the Midwest Pediatric Nephrology Consortium. 
  • Unexpected role of TRPC6 channel in familial nephrotic syndrome: does it have clinical implications? 
  • Urinary tract abnormalities in the nephrotic syndrome. Seven cases demonstrating such an association. 
  • Urine and serum lactic dehydrogenase, lactic dehydrogenase isoenzymes, and alkaline phosphatase in the nephrotic syndrome.