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Subject Areas on Research
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A collagen-based nerve guide conduit for peripheral nerve repair: an electrophysiological study of nerve regeneration in rodents and nonhuman primates.
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A deficit in astroglial organization causes the impaired reactive sprouting in human apolipoprotein E4 targeted replacement mice.
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A high mitochondrial transport rate characterizes CNS neurons with high axonal regeneration capacity.
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A simple technique for augmentation of axonal ingrowth into chondroitinase-treated acellular nerve grafts using nerve growth factor.
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Accuracy of regenerating motor neurons: influence of diffusion in denervated nerve.
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Acidic fibroblast growth factor enhances peripheral nerve regeneration in vivo.
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Acidic fibroblast growth factor enhances regeneration of processes by postnatal mammalian retinal ganglion cells in culture.
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Adult c-Kit(+) progenitor cells are necessary for maintenance and regeneration of olfactory neurons.
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Adult human nasal mesenchymal-like stem cells restore cochlear spiral ganglion neurons after experimental lesion.
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Advances in bioengineered conduits for peripheral nerve regeneration.
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Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures.
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Altered expression of pp60c-src induced by peripheral nerve injury.
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An Eclectic Review of the History of Peripheral Nerve Surgery.
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An apolipoprotein E-mimetic stimulates axonal regeneration and remyelination after peripheral nerve injury.
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An in vitro neurite-promoting antigen functions in axonal regeneration in vivo.
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An in vivo model to quantify motor and sensory peripheral nerve regeneration using bioresorbable nerve guide tubes.
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Analysis of complex matrices functional in neuronal process extension using monoclonal antibodies in vitro and in vivo.
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Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene.
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Anatomic Targets for Breast Reconstruction Neurotization: Past Results and Future Possibilities.
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Apolipoprotein E and brain injury: implications for children.
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Apolipoprotein E epsilon4 allele and outcomes of traumatic spinal cord injury.
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At the interface: convergence of neural regeneration and neural prostheses for restoration of function.
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Autoradiographic evidence that septohippocampal fibers reinnervate fascia dentata denervated by entorhinal lesion during development.
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Axon regeneration pathways identified by systematic genetic screening in C. elegans.
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Axotomized mouse retinal ganglion cells containing melanopsin show enhanced survival, but not enhanced axon regrowth into a peripheral nerve graft.
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Axotomy-induced regulation of c-Jun expression in regenerating rat retinal ganglion cells.
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Bilateral Selective Laryngeal Reinnervation for Bilateral Vocal Fold Paralysis in Children.
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Brain natriuretic peptide improves long-term functional recovery after acute CNS injury in mice.
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Changes in the expression of transcription factors ATF-2 and Fra-2 after axotomy and during regeneration in rat retinal ganglion cells.
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Characteristics of cat skeletal muscles grafted with intact nerves or with anastomosed nerves.
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Characterization of a composite injury model of severe lower limb bone and nerve trauma.
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Ciliary neurotrophic factor is an axogenesis factor for retinal ganglion cells.
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Clinical and Morphologic Outcomes of Minimally Invasive Direct Corneal Neurotization.
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Combining topographical and genetic cues to promote neuronal fate specification in stem cells.
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Competitive and non-competitive re-innervation of mammalian sympathetic neurones by native and foreign fibres.
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Denatured muscle as a nerve conduit: a functional, morphologic, and electrophysiologic evaluation.
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Developmental change in the access to olfactory memories.
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Developmentally regulated changes in femoral nerve regeneration in the mouse and rat.
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Differences between the effect of anisotropic and isotropic laminin and nerve growth factor presenting scaffolds on nerve regeneration across long peripheral nerve gaps.
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Digital sensibility following replantation.
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Double-labeling of saphenous nerve neuron pools: a model for determining the accuracy of axon regeneration at the single neuron level.
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Doublecortin-Like Kinases Promote Neuronal Survival and Induce Growth Cone Reformation via Distinct Mechanisms.
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EMG of reinnervated motor units: a simulation study.
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Effect of modulating macrophage phenotype on peripheral nerve repair
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Effect of nerve growth factor on synaptic depression after axotomy.
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Electrical stimulation alters protein adsorption and nerve cell interactions with electrically conducting biomaterials.
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End-to-side nerve repair. A review.
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Enriching neural stem cell and anti-inflammatory glial phenotypes with electrical stimulation after traumatic brain injury in male rats.
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Entubulation repair with protein additives increases the maximum nerve gap distance successfully bridged with tubular prostheses.
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Epidermal denervation and its effects on keratinocytes and Langerhans cells.
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Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats.
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Factors contributing to preferential motor reinnervation in the primate peripheral nervous system.
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Factors that influence peripheral nerve regeneration: an electrophysiological study of the monkey median nerve.
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Fate of the hippocampal mossy fiber projection after destruction of its postsynaptic targets with intraventricular kainic acid.
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Functional Reorganization of Memory after Traumatic Brain Injury: A Study with H2O Positron Emission Tomography
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Functional and structural changes in mammalian sympathetic neurones following colchicine application to post-ganglionic nerves.
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Functional and structural changes in mammalian sympathetic neurones following interruption of their axons.
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Functional effects of lymphotoxin on crushed peripheral nerve.
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Functional recordings from awake, behaving rodents through a microchannel based regenerative neural interface.
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Human neural stem cell transplants improve motor function in a rat model of Huntington's disease.
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Identification of a peripheral nerve neurite growth-promoting activity by development and use of an in vitro bioassay.
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Immediate early gene expression in axotomized and regenerating retinal ganglion cells of the adult rat.
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Immunoengineering nerve repair.
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Impairment of radial-arm maze performance in rats following lesions involving the cholinergic medial pathway: reversal by arecoline and differential effects of muscarinic and nicotinic antagonists.
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Improved nerve regeneration through piezoelectric vinylidenefluoride-trifluoroethylene copolymer guidance channels.
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In situ gelling hydrogels for conformal repair of spinal cord defects, and local delivery of BDNF after spinal cord injury.
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Increased rate of peripheral nerve regeneration using bioresorbable nerve guides and a laminin-containing gel.
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Increased spontaneous unit activity and appearance of spontaneous negative potentials in the goldfish tectum during refinement of the optic projection.
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Increases in ribosomal RNA within the denervated neuropil of the dentate gyrus during reinnervation: evaluation by in situ hybridization using DNA probes complementary to ribosomal RNA.
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Influence of Touch-Spun Nanofiber Diameter on Contact Guidance during Peripheral Nerve Repair.
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Influence of common drugs and related factors on stroke outcome.
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Influence of lesion size and location on amphetamine-facilitated recovery of beam-walking in rats.
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Influence of terminal nerve branch size on motor neuron regeneration accuracy.
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Inhibition of inducible nitric oxide synthase promotes recovery of motor function in rats after sciatic nerve ischemia and reperfusion.
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Injuring neurons induces neuronal differentiation in a population of hippocampal precursor cells in culture.
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Interaction with CA4-derived fibers accounts for distribution of septohippocampal fibers in rat fascia dentata after entorhinal lesion.
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Interleukin-1 beta promotes functional recovery of crushed peripheral nerve.
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Intraoperative mapping during repeat awake craniotomy reveals the functional plasticity of adult cortex.
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Introduction: peripheral nerve surgery--biology, entrapment, and injuries.
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Levator ani denervation and reinnervation 6 months after childbirth.
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Long-term status of pyramidal cell axon collaterals and apical dendritic spines in denervated cortex.
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Loss and reacquisition of hippocampal synapses after selective destruction of CA3-CA4 afferents with kainic acid.
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Manipulations of the mouse femoral nerve influence the accuracy of pathway reinnervation by motor neurons.
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Measurement of intraoperative nerve conduction velocities during anterior interosseous nerve decompression.
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Mechanisms underlying reversal of motor unit activation order in electrically evoked contractions after spinal cord injury.
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Mechanistic Insights into Sympathetic Neuronal Regeneration: Multitracer Molecular Imaging of Catecholamine Handling After Cardiac Transplantation.
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Merosin promotes neurite growth and Schwann cell migration in vitro and nerve regeneration in vivo: evidence using an antibody to merosin, ARM-1.
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Metallothionein in the central nervous system: Roles in protection, regeneration and cognition.
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Microchannel-based regenerative scaffold for chronic peripheral nerve interfacing in amputees.
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Modulation of Rho GTPase activity alleviates chondroitin sulfate proteoglycan-dependent inhibition of neurite extension.
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Molecular sequelae of topographically guided peripheral nerve repair.
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Monkey median nerve repaired by nerve graft or collagen nerve guide tube.
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Motor functional and morphological findings following end-to-side neurorrhaphy in the rat model.
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Motor neuron regeneration accuracy: balancing trophic influences between pathways and end-organs.
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Motor neuron target selectivity and survival after prolonged axotomy.
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Motor neurons can preferentially reinnervate cutaneous pathways.
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Muscle-Derived Extracellular Vesicles Influence Motor Neuron Regeneration Accuracy.
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N-methyl-D-aspartate receptors strongly regulate postsynaptic activity levels during optic nerve regeneration.
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Netrin-1 and peripheral nerve regeneration in the adult rat.
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Network level properties of short-term plasticity in the somatosensory system.
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Neural circuit repair by low-intensity magnetic stimulation requires cellular magnetoreceptors and specific stimulation patterns.
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Neurite outgrowth is enhanced by anti-idiotypic monoclonal antibodies to the ganglioside GM1.
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Neurotization of elements of the brachial plexus.
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Neurotization of the Nipple-Areola Complex during Implant-Based Reconstruction: Evaluation of Early Sensation Recovery.
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Nogo receptor 1 is expressed by nearly all retinal ganglion cells.
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Nontoxic nerve guide tubes support neovascular growth in transected rat optic nerve.
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Normal spastin gene dosage is specifically required for axon regeneration.
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Overcoming endogenous constraints on neuronal regeneration
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Peripheral nerve regeneration with entubulation repair: comparison of biodegradeable nerve guides versus polyethylene tubes and the effects of a laminin-containing gel.
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Peripheral nerve regeneration: an opinion on channels, scaffolds and anisotropy.
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Peripheral nerve repair with collagen conduits.
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Peripheral neuropathy in mouse hereditary diabetes mellitus. II. Ultrastructural correlates of degenerative and regenerative changes.
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Persistent innervation of mammalian sympathetic neurones by native and foreign fibres.
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Phosphorylated microtubule associated protein (MAP1B-Phos) in the retina during regeneration of the fish optic nerve.
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Physiologic status of regenerated hair cells in the avian inner ear following aminoglycoside ototoxicity.
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Platelet-rich plasma and peripheral nerve regeneration: a potential contraindication to its use after tumor excision.
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Point sources of Schwann cells result in growth into a nerve entubulation repair site in the absence of axons: effects of freeze-thawing.
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Polyethylene glycol fusion repair prevents reinnervation accuracy in rat peripheral nerve.
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Posttraumatic abducens to oculomotor nerve misdirection.
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Predictable Location of Breast Sensory Nerves for Breast Reinnervation.
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Preferential motor reinnervation in the mouse: comparison of femoral nerve repair using a fibrin sealant or suture.
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Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center.
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Protective effect of 21-aminosteroid pretreatment in peripheral nerve low-load crush injury in mature and immature rats.
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Radiation-induced brain injury: low-hanging fruit for neuroregeneration.
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Re-innervation of ganglia transplanted to the neck from different levels of the guinea-pig sympathetic chain.
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Re-innervation of guinea-pig superior cervical ganglion cells by preganglionic fibres arising from different levels of the spinal cord.
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Regenerative scaffold electrodes for peripheral nerve interfacing.
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Regional cardiac sympathetic innervation early and late after transmyocardial laser revascularization.
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Reinnervation accuracy of the rat femoral nerve by motor and sensory neurons.
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Retinal ganglion cells and axons survive optic nerve transection.
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Reverse end-to-side neurotization.
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Reversing nerve-graft polarity in a rat model: the effect on function.
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Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma.
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Role of ornithine decarboxylase and the polyamines in nervous system development: a review.
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Schwann cell influence on motor neuron regeneration accuracy.
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Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid.
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Single-fiber EMG demonstrates reinnervation dynamics after nerve injury.
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Specific connections between nerve cells.
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Specificity of initial synaptic contacts made on guinea-pig superior cervical ganglion cells during regeneration of the cervical sympathetic trunk.
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Spontaneous retinal activity is tonic and does not drive tectal activity during activity-dependent refinement in regeneration.
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Sprouting of noradrenergic fibers in hippocampus after medial septal lesions: contributions of the central and peripheral nervous systems.
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Stabilizing electrode-host interfaces: a tissue engineering approach.
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Suppressive effects of halothane on reactive synaptogenesis in the dentate gyrus of rats.
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Synaptic sites on reinnervated nerve cells visualized at two different times in living mice.
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Tenascin-C expression in dystrophin-related muscular dystrophy.
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The Mammalian-Specific Protein Armcx1 Regulates Mitochondrial Transport during Axon Regeneration.
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The development and recovery of motor function in spinal cats. I. The infant lesion effect.
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The development and recovery of motor function in spinal cats. II. Pharmacological enhancement of recovery.
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The effects of exogenous nitric oxide donor on motor functional recovery of reperfused peripheral nerve.
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The effects of post-ganglionic axotomy on selective synaptic connexions in the superior cervical ganglion of the guinea-pig.
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The influence of physical structure and charge on neurite extension in a 3D hydrogel scaffold.
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The normal organization of the lateral posterior nucleus in the golden hamster and its reorganization after neonatal superior colliculus lesions.
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The organization of afferents to the lateral posterior nucleus in the golden hamster after different combinations of neonatal lesions.
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The organization of the lateral posterior nucleus in neonatal golden hamsters.
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The organization of the lateral posterior nucleus of the golden hamster after neonatal superior colliculus lesions.
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The phosphorylated isoform of microtubule associated protein 1B (MAP1B) is expressed in the visual system of the tench (Tinca tinca, L) during optic nerve regeneration.
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The relationship of functional return to varying methods of nerve repair.
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The role of aligned polymer fiber-based constructs in the bridging of long peripheral nerve gaps.
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The specificity of motor neurone regeneration (preferential reinnervation).
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The use of cultured Schwann cells in nerve repair in a rabbit hind-limb model.
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Thin-film enhanced nerve guidance channels for peripheral nerve repair.
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Topography, cell response, and nerve regeneration.
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Toward Functional Restoration of the Central Nervous System: A Review of Translational Neuroscience Principles.
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Toward a convergence of regenerative medicine, rehabilitation, and neuroprosthetics.
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Tumor necrosis factor promotes motor functional recovery in crushed peripheral nerve.
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Keywords of People
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Choi, Steven Sok,
Associate Professor of Medicine,
Medicine, Gastroenterology
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James, Michael Lucas,
Associate Professor of Anesthesiology,
Anesthesiology
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Stinnett, Sandra Sue,
Associate Professor of Biostatistics & Bioinformatics,
Biostatistics & Bioinformatics
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Velkey, John Matthew,
Assistant Professor of the Practice of Medical Education in the Department of Cell Biology,
Cell Biology