S100 Proteins

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  Subject Areas on Research

  • A Diffuse Leptomeningeal Glioneuronal Tumor Without Diffuse Leptomeningeal Involvement: Detailed Molecular and Clinical Characterization. 
  • A blood-based biomarker panel to detect acute stroke. 
  • A panel of antibodies useful in the cytologic diagnosis of metastatic melanoma. 
  • A recurrent cerebellar lesion in a young boy. 
  • Altered expression of pp60c-src induced by peripheral nerve injury. 
  • Apolipoprotein E genotype and S100beta after cardiac surgery: is inflammation the link? 
  • CaN19 expression in benign and malignant hyperplasias of the skin and oral mucosa: evidence for a role in regenerative differentiation. 
  • Cell adhesion protein expression in melanocytic matricoma. 
  • Cerebral emboli and serum S100beta during cardiac operations. 
  • Changing outcome from aneurysmal subarachnoid hemorrhage: another step closer. 
  • Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4. 
  • Clinical usefulness of a biomarker-based diagnostic test for acute stroke: the Biomarker Rapid Assessment in Ischemic Injury (BRAIN) study. 
  • Consolidation with high-dose combination alkylating agents with bone marrow transplantation significantly improves disease-free survival in hormone-insensitive metastatic breast cancer in complete remission compared with intensive standard-dose chemotherapy alone. 
  • Continuous human glioma-derived cell lines UC-11MG and UC-302MG. Morphologic, immunocytochemical and chromosomal characterization. 
  • Cutaneous Burn Injury Modulates Urinary Antimicrobial Peptide Responses and the Urinary Microbiome. 
  • Detection and quantification of S-100 protein in ocular tissues and fluids from patients with intraocular melanoma. 
  • Detection of cytoplasmic S-100 protein in primary and metastatic intraocular melanomas. 
  • Discriminative capacity of biomarkers for acute stroke in the emergency department. 
  • Early biomarkers of stroke. 
  • Effect of Mts1 on the structure and activity of nonmuscle myosin II. 
  • Evaluation of new putative tumor markers for melanoma. 
  • Fine-needle aspiration of neural lesions. 
  • Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K. 
  • Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways. 
  • Granular cell tumors of the breast. Steroid receptor analysis and localization of carcinoembryonic antigen, myoglobin, and S100 protein. 
  • Heterogeneity of Genotypic and phenotypic characteristics of fifteen permanent cell lines derived from human gliomas. 
  • Human S100A15 splice variants are differentially expressed in inflammatory skin diseases and regulated through Th1 cytokines and calcium. 
  • Hydroxychloroquine-induced hyperpigmentation: the staining pattern. 
  • Immunohistochemical markers in fibrohistiocytic lesions: factor XIIIa, CD34, S-100 and p75. 
  • Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma. 
  • Innate immunity and antimicrobial defense systems in psoriasis. 
  • Isolated and synchronous vulvar granular cell tumors: a clinicopathologic study of 17 cases in 13 patients. 
  • Malignant melanoma with a myxoid stroma: a diagnostic pitfall on fine-needle aspiration biopsy. 
  • MicroRNA induced cardiac reprogramming in vivo: evidence for mature cardiac myocytes and improved cardiac function. 
  • MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. 
  • Novel diagnostic test for acute stroke. 
  • Papillary glioneuronal tumor: a new variant of mixed neuronal-glial neoplasm. 
  • Pathologic quiz case: pituitary mass in a 48-year-old woman. 
  • Primary optic nerve meningiomas in F344 rats. 
  • Proteomic biomarkers of intra-amniotic inflammation: relationship with funisitis and early-onset sepsis in the premature neonate. 
  • RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression. 
  • Redefining the Autonomic Nerve Distribution of the Bladder Using 3-Dimensional Image Reconstruction. 
  • S100A15, an antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4. 
  • S100B and brain natriuretic peptide predict functional neurological outcome after intracerebral haemorrhage. 
  • S100beta and postcardiac surgery neurological dysfunction: reasons to disregard any link. 
  • Serum S100 protein as a marker of cerebral damage during cardiac surgery. 
  • Statistical analysis of the concordance of immunohistochemical stains with the final diagnosis in spitzoid neoplasms. 
  • Surgical resection of locally advanced granular cell tumor of the orbit. 
  • The role of aligned polymer fiber-based constructs in the bridging of long peripheral nerve gaps. 
  • The skin transcriptome in hidradenitis suppurativa uncovers an antimicrobial and sweat gland gene signature which has distinct overlap with wounded skin. 
  • The tumor biology of melanoma nodal metastases. 
  • The use of S100B as a biomarker in subarachnoid hemorrhage: clarity in its promise and limits. 
  • Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance. 
  • Update: biomarkers for idiopathic inflammatory myopathies. 
  • Uveitis in children. 
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  Keywords of People

  • James, Michael Lucas, Associate Professor of Anesthesiology, Anesthesiology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Yan, Hai, Adjunct Professor of Pathology, Pathology