Neuraminidase

• 

  Subject Areas on Research

  • Adoptive transfer and specific active immunization of patients with malignant melanoma. 
  • Carbohydrate on human factor VIII/von Willebrand factor. Impairment of function by removal of specific galactose residues. 
  • Characterization of human serum dipeptidyl peptidase IV (CD26) and analysis of its autoantibodies in patients with rheumatoid arthritis and other autoimmune diseases. 
  • Detection of a novel marker in the bronchial secretions of patients with non-small cell lung cancer using the 4B5 monoclonal antibody. 
  • Development and preclinical evaluation of an alphavirus replicon vaccine for influenza. 
  • Differential expression of CD43 (leukosialin, sialophorin) by mononuclear phagocyte populations. 
  • Distribution of anionic sites on surfaces of retinal cells: a study using cationized ferritin. 
  • Effect of desialylation on the biological properties of human plasminogen. 
  • Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation. 
  • Enzymatic susceptibility and spontaneous release of human melanoma tumor-associated antigens. 
  • Factor VIII/von Willebrand protein. Modification of its carbohydrate causes reduced binding to platelets. 
  • How sticky should a virus be? The impact of virus binding and release on transmission fitness using influenza as an example. 
  • Human leukemia antigens: partial isolation and characterization. 
  • Increased expression of sialyl-dimeric LeX antigen in liver metastases of human colorectal carcinoma. 
  • Intralesional BCG, intravenous immune lymphocytes, and immunization with neuraminidase-treated tumor cells to manage melanoma; A clinical assessment. 
  • Mammalian beta-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains. 
  • Management of recurrent melanoma of the extremity. 
  • Non-specific and specific active immunotherapy in a B16 murine melanoma system. 
  • Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid. 
  • Quantification and enzymic identification of conjunctival surface mucus. 
  • Relationship of sialic acid to function and in vivo survival of human factor VIII/von Willebrand factor protein. 
  • Role of carbohydrate in biological functions of Friend murine leukemia virus gp71. 
  • Role of carbohydrate in determining the immunochemical properties of the major glycoprotein (gp71) of Friend murine leukemia virus. 
  • Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure. 
  • The HB-6, CDw75, and CD76 differentiation antigens are unique cell-surface carbohydrate determinants generated by the beta-galactoside alpha 2,6-sialyltransferase. 
  • The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor.