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Subject Areas on Research
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3-Dimensional visualization of lesions in rat brain using magnetic resonance imaging microscopy.
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6-Hydroxydopamine injections into the nigrostriatal pathway attenuate striatal malonate and 3-nitropropionic acid lesions.
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A non-pungent resiniferatoxin analogue, phorbol 12-phenylacetate 13 acetate 20-homovanillate, reveals vanilloid receptor subtypes on rat trigeminal ganglion neurons.
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Acrylamide-regulated neurofilament expression in rat pheochromocytoma cells.
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Activated human microglia produce the excitotoxin quinolinic acid.
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Activation of Nrf2 Pathway Contributes to Neuroprotection by the Dietary Flavonoid Tiliroside.
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Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture.
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Alpha7 nicotinic acetylcholine receptors targeted by cholinergic developmental neurotoxicants: nicotine and chlorpyrifos.
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Antimalarial Drug Artemether Inhibits Neuroinflammation in BV2 Microglia Through Nrf2-Dependent Mechanisms.
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Apolipoprotein E protects against NMDA excitotoxicity.
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Attenuation of NMDA receptor activity and neurotoxicity by nitroxyl anion, NO-.
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Attenuation of the neurotoxic effect of A beta amyloid peptide by apolipoprotein E.
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Botulinum toxin treatment of social anxiety disorder with hyperhidrosis: a placebo-controlled double-blind trial.
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Brevetoxin-6 (PbTx-6), a nonaromatic marine neurotoxin, is a ligand of the aryl hydrocarbon receptor.
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Cellular determinants of reduced adaptability of the aging brain: neurotransmitter utilization and cell signaling responses after MDMA lesions.
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Chapter 12 Neurotoxicology of neuromuscular transmission.
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Chlorpyrifos targets developing glia: effects on glial fibrillary acidic protein.
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Clorgyline and deprenyl attenuate striatal malonate and 3-nitropropionic acid lesions.
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Critical periods for the role of oxidative stress in the developmental neurotoxicity of chlorpyrifos and terbutaline, alone or in combination.
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Developmental neurotoxic effects of chlorpyrifos on acetylcholine and serotonin pathways in an avian model.
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Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: effects on nuclear transcription factors involved in cell replication and differentiation.
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Developmental neurotoxicity of chlorpyrifos: delayed targeting of DNA synthesis after repeated administration.
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Developmental neurotoxicity of succeeding generations of insecticides.
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Disparate developmental neurotoxicants converge on the cyclic AMP signaling cascade, revealed by transcriptional profiles in vitro and in vivo.
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Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes.
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Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium.
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Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter.
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Early differential elevation and persistence of phosphorylated cAMP-response element binding protein (p-CREB) in the central nervous system of hens treated with diisopropyl phosphorofluoridate, an OPIDN-causing compound.
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Effects of neurotoxic doses of methamphetamine on potassium and amphetamine evoked overflow of dopamine in the striatum of awake rats.
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Excitatory amino acid neurotoxins: selectivity, specificity, and mechanisms of action. Based on an NRP one-day conference held June 30, 1980.
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Fleeting activation of ionotropic glutamate receptors sensitizes cortical neurons to complement attack.
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Gene-environment interactions: neurodegeneration in non-mammals and mammals.
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Genetic aspects of behavioral neurotoxicology.
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Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice.
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Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice.
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Insight into the Mode of Action of Haedoxan A from Phryma leptostachya.
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Intravesical ultrapotent vanilloid receptor agonists: acute effects on animal models of bladder irritation.
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Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos?
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Kainic acid: neurophysiological and neurotoxic actions.
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Learning about cognition risk with the radial-arm maze in the developmental neurotoxicology battery.
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Learning impairment caused by a toxin produced by Pfiesteria piscicida infused into the hippocampus of rats.
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Lipid diversity among botulinum neurotoxin-producing clostridia.
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Modeling the developmental neurotoxicity of nicotine in vitro: cell acquisition, growth and viability in PC12 cells.
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Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson's Disease Patients.
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Molecular conformation of erabutoxin b; atomic coordinates at 2.5 A resolution.
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Morphometric analysis for early detection of changes in cellular structure in a toxicological experiment.
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Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits.
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Neonatal chlorpyrifos exposure targets multiple proteins governing the hepatic adenylyl cyclase signaling cascade: implications for neurotoxicity.
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Neonatal parathion exposure and interactions with a high-fat diet in adulthood: Adenylyl cyclase-mediated cell signaling in heart, liver and cerebellum.
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Neuronal pentraxin 1: a novel mediator of hypoxic-ischemic injury in neonatal brain.
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Neuroprotective and neurodestructive effects of nitric oxide and redox congeners.
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Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease.
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Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor.
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Neurotoxicity of carbonyl sulfide in F344 rats following inhalation exposure for up to 12 weeks.
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Nicotine is a neurotoxin in the adolescent brain: critical periods, patterns of exposure, regional selectivity, and dose thresholds for macromolecular alterations.
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Nrf2-mediated protection against 6-hydroxydopamine.
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Oxidative stress from diverse developmental neurotoxicants: antioxidants protect against lipid peroxidation without preventing cell loss.
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Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain.
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Persisting behavioral consequences of prenatal domoic acid exposure in rats.
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Presynaptic input regulates development of beta-adrenergic control of rat brain ornithine decarboxylase: effects of 6-hydroxydopamine or propranolol.
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Protein kinase C is a target for diverse developmental neurotoxicants: transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells.
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Pyrrole oxidation and protein cross-linking as necessary steps in the development of gamma-diketone neuropathy.
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Quantitative morphological assessment reveals neuronal and glial deficits in hippocampus after a brief subtoxic exposure to chlorpyrifos in neonatal rats.
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Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
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Recovery of presynaptic dopaminergic functioning in rats treated with neurotoxic doses of methamphetamine.
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Reduced aspartate release from rat hippocampal synaptosomes loaded with Clostridial toxin light chain by electroporation: evidence for an exocytotic mechanism.
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Regulation of complex I by Engrailed is complex too.
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Requirement for superoxide in excitotoxic cell death.
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Restorative effects of GDNF on striatal dopamine release in rats treated with neurotoxic doses of methamphetamine.
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Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter.
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Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels.
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Temporary autonomic modulation with botulinum toxin type A to reduce atrial fibrillation after cardiac surgery.
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The Kv2.1 channels mediate neuronal apoptosis induced by excitotoxicity.
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The differential preference of scorpion alpha-toxins for insect or mammalian sodium channels: implications for improved insect control.
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The dopamine transporter. The cloned target site of parkinsonism-inducing toxins and of drugs of abuse.
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The glutamate transport inhibitor L-trans-pyrrolidine-2,4-dicarboxylate indirectly evokes NMDA receptor mediated neurotoxicity in rat cortical cultures.
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The insecticidal potential of scorpion beta-toxins.
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The neurotoxin quinolinic acid is increased in spinal cords of mice with herpes simplex virus encephalitis.
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The sea urchin embryo as a model for mammalian developmental neurotoxicity: ontogenesis of the high-affinity choline transporter and its role in cholinergic trophic activity.
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The sensorimotor striatum is necessary for serial order learning.
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The toxin-agglutinin fold. A new group of small protein structures organized around a four-disulfide core.
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The use of zebrafish (Danio rerio) as a model system in neurobehavioral toxicology.
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Three-dimensional (3D) brain microphysiological system for organophosphates and neurochemical agent toxicity screening.
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Toward an implantable functional electrical stimulation device to correct strabismus.
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Toxicity of L-proline toward rat hippocampal neurons.
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Toxin and kinetic profile of rat brain type III sodium channels expressed in Xenopus oocytes.
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Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants.
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Trophic control of the ornithine decarboxylase/polyamine system in neonatal rat brain regions: lesions caused by 6-hydroxydopamine produce effects selective for cerebellum.
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Use of excitatory amino acids to make axon-sparing lesions of hypothalamus.
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Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: signal transduction cascades.
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Ventral cochlear nucleus responses to contralateral sound are mediated by commissural and olivocochlear pathways.
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Virtual neuropathology: three-dimensional visualization of lesions due to toxic insult.
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Zebrafish as a neurotoxicological model.
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kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica.
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Keywords of People