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Subject Areas on Research
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A clinical practice guideline for treating tobacco use and dependence: 2008 update. A U.S. Public Health Service report.
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A clinical practice guideline for treating tobacco use and dependence: A US Public Health Service report. The Tobacco Use and Dependence Clinical Practice Guideline Panel, Staff, and Consortium Representatives.
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A programmable smoke delivery device for PET imaging with cigarettes containing 11C-nicotine.
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A psychometric evaluation of the Fagerström Test for Nicotine Dependence in PTSD smokers.
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A randomized trial of nicotine replacement therapy in combination with reduced-nicotine cigarettes for smoking cessation.
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A study of the potential confounding effects of diet, caffeine, nicotine and lorazepam on the stability of plasma and urinary homovanillic acid levels in patients with schizophrenia.
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A unique role for striatal serotonergic systems in the withdrawal from adolescent nicotine administration.
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ADHD and smoking: from genes to brain to behavior.
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Acoustic startle and prepulse inhibition predict smoking lapse in posttraumatic stress disorder.
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Activity patterns in mesolimbic regions in rats during operant tasks for reward.
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Acute and chronic effects of nicotine on synthesis and storage of catecholamines in the rat adrenal medulla.
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Acute and chronic interactive treatments of serotonin 5HT2C and dopamine D1 receptor systems for decreasing nicotine self-administration in female rats.
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Acute and chronic nicotine effects on working memory in aged rats.
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Acute and chronic nicotinic interactions with dopamine systems and working memory performance.
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Acute effects of nicotine and mecamylamine on tobacco withdrawal symptoms, cigarette reward and ad lib smoking.
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Acute nicotine interactions with nicotinic and muscarinic antagonists: working and reference memory effects in the 16-arm radial maze.
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Acute oral 18-methoxycoronaridine (18-MC) decreases both alcohol intake and IV nicotine self-administration in rats.
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Acute stimulation of ornithine decarboxylase in neonatal rat brain regions by nicotine: a central receptor-mediated process?
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Additive and synergistic effects of fetal nicotine and dexamethasone exposure on cholinergic synaptic function in adolescence and adulthood: Implications for the adverse consequences of maternal smoking and pharmacotherapy of preterm delivery.
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Adherence to nicotine replacement therapy among pregnant smokers.
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Administration of nicotine to adolescent rats evokes regionally selective upregulation of CNS alpha 7 nicotinic acetylcholine receptors.
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Adolescent and adult rats respond differently to nicotine and alcohol: motor activity and body temperature.
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Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase.
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Adolescent nicotine administration changes the responses to nicotine given subsequently in adulthood: adenylyl cyclase cell signaling in brain regions during nicotine administration and withdrawal, and lasting effects.
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Adolescent nicotine exposure alters cardiac autonomic responsiveness: beta-adrenergic and m2-muscarinic receptors and their linkage to adenylyl cyclase.
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Adolescent nicotine exposure causes persistent upregulation of nicotinic cholinergic receptors in rat brain regions.
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Adolescent nicotine exposure produces immediate and long-term changes in CNS noradrenergic and dopaminergic function.
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Adolescent nicotine treatment changes the response of acetylcholine systems to subsequent nicotine administration in adulthood.
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Adolescent nicotine: deficits in immune function.
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Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates.
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Adolescent vulnerabilities to chronic alcohol or nicotine exposure: findings from rodent models.
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Adolescent-onset nicotine self-administration modeled in female rats.
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Adolescents and adults differ in the immediate and long-term impact of nicotine administration and withdrawal on cardiac norepinephrine.
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Adverse benzo[a]pyrene effects on neurodifferentiation are altered by other neurotoxicant coexposures: interactions with dexamethasone, chlorpyrifos, or nicotine in PC12 cells.
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Age Moderates Smokers' Subjective Response to Very-Low Nicotine Content Cigarettes: Evidence from a Randomized Controlled Trial.
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Airway sensory replacement combined with nicotine replacement for smoking cessation. A randomized, placebo-controlled trial using a citric acid inhaler.
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Alpha7 nicotinic acetylcholine receptors targeted by cholinergic developmental neurotoxicants: nicotine and chlorpyrifos.
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Alteration of the alkaloid profile in genetically modified tobacco reveals a role of methylenetetrahydrofolate reductase in nicotine N-demethylation.
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Altered development of basal and forskolin-stimulated adenylate cyclase activity in brain regions of rats exposed to nicotine prenatally.
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Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cells.
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Amelioration strategies fail to prevent tobacco smoke effects on neurodifferentiation: Nicotinic receptor blockade, antioxidants, methyl donors.
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Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats.
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Amitifadine, a triple reuptake inhibitor, reduces self-administration of the opiate remifentanil in rats.
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An animal model of adolescent nicotine exposure: effects on gene expression and macromolecular constituents in rat brain regions.
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Analysis of reinforcement by varying smoke component concentrations.
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Anticipated Effects of Nicotine Reduction on Youth Smoking Initiation and Maintenance.
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Antidepressant effects of nicotine in an animal model of depression.
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Antidepressant-like effects of nicotine and reduced nicotinic receptor binding in the Fawn-Hooded rat, an animal model of co-morbid depression and alcoholism.
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Anxiolytic effects of nicotine in zebrafish.
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Appeal, subjective effects, and relative reinforcing effects of JUUL that vary in flavor and nicotine content.
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Arterial nicotine kinetics during cigarette smoking and intravenous nicotine administration: implications for addiction.
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Assessing the effects of chronic sazetidine-A delivery on nicotine self-administration in both male and female rats.
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Asthma exacerbation after administration of nicotine nasal spray for smoking cessation.
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Attention as a target of intoxication: insights and methods from studies of drug abuse.
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Baclofen interactions with nicotine in rats: effects on memory.
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Baseline expression of alpha4beta2* nicotinic acetylcholine receptors predicts motivation to self-administer nicotine.
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Basic Science and Public Policy: Informed Regulation for Nicotine and Tobacco Products.
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Behavioral effects of acute hexamethonium in rats chronically intoxicated with nicotine.
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Blockade of smoking satisfaction using the peripheral nicotinic antagonist trimethaphan.
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Brain indices of nicotine's effects on attentional bias to smoking and emotional pictures and to task-relevant targets.
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Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette.
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Bupropion-varenicline interactions and nicotine self-administration behavior in rats.
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Bupropion/zonisamide combination to assist smokers to switch from combustible cigarettes to electronic nicotine delivery systems (ENDS).
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CT Findings and Patterns of e-Cigarette or Vaping Product Use-Associated Lung Injury: A Multicenter Cohort of 160 Cases.
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Capsaicin and nicotine both activate a subset of rat trigeminal ganglion neurons.
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Capsazepine, a vanilloid receptor antagonist, inhibits nicotinic acetylcholine receptors in rat trigeminal ganglia.
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Challenges and solutions for recruiting pregnant smokers into a nicotine replacement therapy trial.
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Characterization of the facilitative effects of perinatal choline supplementation on timing and temporal memory.
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Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis.
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Cholinergic and adrenergic activating agents as antagonists of the EEG effects of hemicholinium-3.
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Cholinergic receptors in heart and brainstem of rats exposed to nicotine during development: implications for hypoxia tolerance and perinatal mortality.
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Cholinergic stimulation of phosphatidylinositol hydrolysis by rat corneal epithelium in vitro.
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Cholinergic synaptic signaling mechanisms underlying behavioral teratogenicity: effects of nicotine, chlorpyrifos, and heroin converge on protein kinase C translocation in the intermedial part of the hyperstriatum ventrale and on imprinting behavior in an avian model.
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Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates.
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Chronic exposure to nicotine does not prevent neurocognitive decline after cardiac surgery.
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Chronic haloperidol administration does not block acute nicotine-induced improvements in radial-arm maze performance in the rat.
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Chronic infusions of mecamylamine into the medial habenula: Effects on nicotine self-administration in rats.
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Chronic inhibition of alpha4beta2 nicotinic receptors in the ventral hippocampus of rats: impacts on memory and nicotine response.
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Chronic memantine decreases nicotine self-administration in rats.
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Chronic nicotine and dizocilpine effects on nicotinic and NMDA glutamatergic receptor regulation: interactions with clozapine actions and attentional performance in rats.
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Chronic nicotine and dizocilpine effects on regionally specific nicotinic and NMDA glutamate receptor binding.
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Chronic nicotine and withdrawal effects on body weight and food and water consumption in female rats.
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Chronic nicotine and withdrawal effects on radial-arm maze performance in rats.
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Chronic nicotine interactions with clozapine and risperidone and attentional function in rats.
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Chronic nicotine reverses working memory deficits caused by lesions of the fimbria or medial basalocortical projection.
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Chronic nicotine working and reference memory effects in the 16-arm radial maze: interactions with D1 agonist and antagonist drugs.
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Chronic nicotinic agonist and antagonist effects on T-maze alternation.
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Chronic prenatal nicotine exposure sensitizes rat brain to acute postnatal nicotine challenge as assessed with ornithine decarboxylase.
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Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.
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Chronic transdermal nicotine patch treatment effects on cognitive performance in age-associated memory impairment.
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Cigarette desirability and nicotine preference in smokers.
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Cigarette smoking behavior in conjoined twins.
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Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors.
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Citric acid aerosol as a potential smoking cessation aid.
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Clinical evaluation of a citric acid inhaler for smoking cessation.
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Clinical trials using ascorbic acid aerosol to aid smoking cessation.
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Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response.
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Co-expression of nAChRs and molecules of the bitter taste transduction pathway by epithelial cells of intrapulmonary airways.
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Cognitive and Behavioral Impairments Evoked by Low-Level Exposure to Tobacco Smoke Components: Comparison with Nicotine Alone.
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Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia.
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Cognitive effects of nicotine.
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Combined acetaldehyde and nicotine exposure depresses cardiac contraction in ventricular myocytes: prevention by folic acid.
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Combined administration of agonist-antagonist as a method of regulating receptor activation.
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Comparison of brain nicotine uptake from electronic cigarettes and combustible cigarettes.
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Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior.
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Consequences of smoking during pregnancy on maternal health.
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Correlates of support for a nicotine-reduction policy in smokers with 6-week exposure to very low nicotine cigarettes.
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Cortical activity differs during nicotine deprivation versus satiation in heavy smokers.
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Cost-effectiveness analysis of the first-line therapies for nicotine dependence.
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Cost-effectiveness of pharmacotherapies for nicotine dependence in primary care settings: a multinational comparison.
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Critical review: nicotine for the fetus, the infant and the adolescent?
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Cryptic brain cell injury caused by fetal nicotine exposure is associated with persistent elevations of c-fos protooncogene expression.
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D-cycloserine selectively decreases nicotine self-administration in rats with low baseline levels of response.
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Deficits in development of central cholinergic pathways caused by fetal nicotine exposure: differential effects on choline acetyltransferase activity and [3H]hemicholinium-3 binding.
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Depressive characteristics of FSL rats: involvement of central nicotinic receptors.
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Design considerations for a study to evaluate the impact of smoking cessation treatment on stimulant use outcomes in stimulant-dependent individuals.
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Developing fit-for-purpose self-report instruments for assessing consumer responses to tobacco and nicotine products: the ABOUT™ Toolbox initiative.
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Development and Piloting Testing of an Experimental Tobacco and Nicotine Product Marketplace.
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Development of [3H]nicotine binding sites in brain regions of rats exposed to nicotine prenatally via maternal injections or infusions.
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Development of a citric acid aerosol as a smoking cessation aid.
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Development of ligands for in vivo imaging of cerebral nicotinic receptors.
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Development of nicotinic drug therapy for cognitive disorders.
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Development of nicotinic responses in the rat adrenal medulla and long-term effects of neonatal nicotine administration.
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Developmental Neurotoxicity of Tobacco Smoke Directed Toward Cholinergic and Serotonergic Systems: More Than Just Nicotine.
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Developmental cholinotoxicants: nicotine and chlorpyrifos.
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Developmental nicotine exposure and masculinization of the rat preoptic area.
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Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products.
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Dextromethorphan interactions with histaminergic and serotonergic treatments to reduce nicotine self-administration in rats.
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Did the acute impact of the COVID-19 pandemic on drinking or nicotine use persist? Evidence from a cohort of emerging adults followed for up to nine years.
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Differential effects of non-nicotine tobacco constituent compounds on nicotine self-administration in rats.
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Differential efficacies of the nicotinic α4β2 desensitizing agents in reducing nicotine self-administration in female rats.
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Discriminability of nicotine in tobacco smoke: implications for titration.
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Disrupting nicotine reinforcement: from cigarette to brain.
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Dissociating nicotine and nonnicotine components of cigarette smoking.
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Dissociating the nicotine and airway sensory effects of smoking.
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Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes.
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Do heavy smokers need a higher replacement dose of nicotine to quit?
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Does concurrent or prior nicotine exposure interact with neonatal hypoxia to produce cardiac cell damage?
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Does prenatal nicotine exposure sensitize the brain to nicotine-induced neurotoxicity in adolescence?
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Does smokeless tobacco cause hypertension?
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Dynamic and multimodal responses of gustatory cortical neurons in awake rats.
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EEG, physiology, and task-related mood fail to resolve across 31 days of smoking abstinence: relations to depressive traits, nicotine exposure, and dependence.
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Editorial: Smoking, catecholamines, and the heart.
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Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial.
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Effect of naloxone on cigarette smoking.
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Effects of advertisements on smokers' interest in trying e-cigarettes: the roles of product comparison and visual cues.
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Effects of caffeine on alcohol consumption and nicotine self-administration in rats.
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Effects of chronic nicotine administration on the denervated rat adrenal medulla.
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Effects of chronic nicotine and methylphenidate in adults with attention deficit/hyperactivity disorder.
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Effects of controlled nicotine doses upon punished and non-punished responding in humans.
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Effects of low nicotine content cigarettes on smoke intake.
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Effects of maternal nicotine injections on brain development in the rat: ornithine decarboxylase activity, nucleic acids and proteins in discrete brain regions.
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Effects of monetary contingencies on smoking relapse: influences of trait depression, personality, and habitual nicotine intake.
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Effects of nicotine and mecamylamine on choice accuracy in an operant visual signal detection task in female rats.
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Effects of nicotine on brain responses to emotional pictures.
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Effects of nicotine on novelty detection and memory recognition performance: double-blind, placebo-controlled studies of smokers and nonsmokers.
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Effects of nicotinic dimethylaminoethyl esters on working memory performance of rats in the radial-arm maze.
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Effects of postnatal reserpine administration on sympatho-adrenal development in the rat.
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Effects of prenatal nicotine exposure on biochemical development of rat brain regions: maternal drug infusions via osmotic minipumps.
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Effects of prenatal nicotine exposure on development of central and peripheral cholinergic neurotransmitter systems. Evidence for cholinergic trophic influences in developing brain.
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Effects of prenatal nicotine exposure on neuronal development: selective actions on central and peripheral catecholaminergic pathways.
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Effects of prenatal nicotine exposure on primate brain development and attempted amelioration with supplemental choline or vitamin C: neurotransmitter receptors, cell signaling and cell development biomarkers in fetal brain regions of rhesus monkeys.
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Effects of quitting smoking on EEG activation and attention last for more than 31 days and are more severe with stress, dependence, DRD2 A1 allele, and depressive traits.
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Effects of reduced nicotine content cigarettes on individual withdrawal symptoms over time and during abstinence.
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Effects of reserpine on the adrenal medulla of the spontaneously hypertensive rat.
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Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats.
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Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats.
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Effects of smoking abstinence on adult smokers with and without attention deficit hyperactivity disorder: results of a preliminary study.
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Effects of smoking on the acoustic startle response and prepulse inhibition in smokers with and without posttraumatic stress disorder.
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Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene.
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Effects of tobacco smoking and nicotine on cancer treatment.
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Effects of training dose on the relationship between discriminative-stimulus and self-reported drug effects of d-amphetamine in humans.
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Effects of transdermal nicotine on lateralized identification and memory interference.
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Electronic Cigarettes: A Pro-Con Review of the Current Literature.
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Electronic cigarette liquid exposure induces flavor-dependent osteotoxicity and increases expression of a key bone marker, collagen type I.
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Emergence of depression during early abstinence in depressed and non-depressed women smokers.
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Evaluation of a reduced nicotine product standard: Moderating effects of and impact on cannabis use.
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Evaluation of the association between maternal smoking, childhood obesity, and metabolic disorders: a national toxicology program workshop review.
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Exposure to environmental tobacco smoke during pregnancy in rats yields less effect on indices of brain cell number and size than does postnatal exposure.
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Extinguishing the rewarding value of smoke cues: pharmacological and behavioral treatments.
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Fetal and adolescent nicotine administration: effects on CNS serotonergic systems.
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Fetal nicotine exposure ablates the ability of postnatal nicotine challenge to release norepinephrine from rat brain regions.
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Fetal nicotine exposure alters ontogeny of M1-receptors and their link to G-proteins.
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Fetal nicotine exposure produces postnatal up-regulation of adenylate cyclase activity in peripheral tissues.
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Fetal nicotine or cocaine exposure: which one is worse?
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Fetal nicotinic overload, blunted sympathetic responsivity, and obesity.
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Four-week nicotine skin patch treatment effects on cognitive performance in Alzheimer's disease.
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Gain modulation by nicotine in macaque v1.
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Genome-wide association for smoking cessation success in a trial of precessation nicotine replacement.
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Genome-wide association for smoking cessation success: participants in a trial with adjunctive denicotinized cigarettes.
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Gestational exposure to nicotine and/or benzo[a]pyrene causes long-lasting neurobehavioral consequences.
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Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: a PET study with 2-18F-FA-85380.
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Guidelines on nicotine dose selection for in vivo research.
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Haloperidol increases smoking in patients with schizophrenia.
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Haloperidol reduces smoking of both nicotine-containing and denicotinized cigarettes.
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Heterogeneity across brain regions and neurotransmitter interactions with nicotinic effects on memory function.
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Histamine H(1) antagonist treatment with pyrilamine reduces nicotine self-administration in rats.
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Histamine H1 receptor involvement in prepulse inhibition and memory function: relevance for the antipsychotic actions of clozapine.
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Human functional neuroimaging in nicotine and tobacco research: basics, background, and beyond.
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IV nicotine self-administration in rats using a consummatory operant licking response: sensitivity to serotonergic, glutaminergic and histaminergic drugs.
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IV nicotine self-administration in rats using the consummatory operant licking response.
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Idazoxan blocks the nicotine-induced reversal of the memory impairment caused by the NMDA glutamate receptor antagonist dizocilpine.
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Identification of muscarinic acetylcholine receptors in isolated canine lingual epithelia via voltage clamp measurements.
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If nicotine is a developmental neurotoxicant in animal studies, dare we recommend nicotine replacement therapy in pregnant women and adolescents?
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Impact of acute nicotine exposure on monoaminergic systems in adolescent and adult male and female rats.
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Impact of adolescent nicotine exposure on adenylyl cyclase-mediated cell signaling: enzyme induction, neurotransmitter-specific effects, regional selectivities, and the role of withdrawal.
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Impact of fetal nicotine exposure on development of rat brain regions: critical sensitive periods or effects of withdrawal?
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Impact of short access nicotine self-administration on expression of α4β2* nicotinic acetylcholine receptors in non-human primates.
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Impaired cardiac function during postnatal hypoxia in rats exposed to nicotine prenatally: implications for perinatal morbidity and mortality, and for sudden infant death syndrome.
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Improvement of attentional function with antagonism of nicotinic receptors in female rats.
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In search of a mechanism for receptor-mediated neurobehavioral teratogenesis by nicotine: catecholamine release by nicotine in immature rat brain regions.
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In utero exposure to nicotine and chlorpyrifos alone, and in combination produces persistent sensorimotor deficits and Purkinje neuron loss in the cerebellum of adult offspring rats.
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In vivo regulation of [3H]acetylcholine recognition sites in brain by nicotinic cholinergic drugs.
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Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.
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Increased nicotine self-administration following prenatal exposure in female rats.
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Increased subjective and reinforcing effects of initial nicotine exposure in young adults with attention deficit hyperactivity disorder (ADHD) compared to matched peers: results from an experimental model of first-time tobacco use.
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Increases in impulsivity following smoking abstinence are related to baseline nicotine intake and boredom susceptibility.
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Induction of tyrosine hydroxylase in the locus coeruleus of transgenic mice in response to stress or nicotine treatment: lack of activation of tyrosine hydroxylase promoter activity.
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Inhalation of vapor from black pepper extract reduces smoking withdrawal symptoms.
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Inhibition of DNA synthesis in neonatal rat brain regions caused by acute nicotine administration.
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Inter-relationships between conditioned and primary reinforcement in the maintenance of cigarette smoking.
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Interaction of nicotinic and histamine H(3) systems in the radial-arm maze repeated acquisition task.
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Invalidity of an Oft-Cited Estimate of the Relative Harms of Electronic Cigarettes.
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Is binding to nicotinic acetylcholine and dopamine receptors related to working memory in rats?
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Ketanserin attenuates nicotine-induced working memory improvement in rats.
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Ketanserin, a 5-HT2 receptor antagonist, decreases nicotine self-administration in rats.
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Kinetics of brain nicotine accumulation in dependent and nondependent smokers assessed with PET and cigarettes containing 11C-nicotine.
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Lasting effects of nicotine treatment and withdrawal on serotonergic systems and cell signaling in rat brain regions: separate or sequential exposure during fetal development and adulthood.
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Lorcaserin, a 5-HT2C agonist, decreases nicotine self-administration in female rats.
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Loss of neonatal hypoxia tolerance after prenatal nicotine exposure: implications for sudden infant death syndrome.
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Low-dose mecamylamine improves learning of rats in the radial-arm maze repeated acquisition procedure.
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Low-nicotine regenerated smoke aerosol reduces desire for cigarettes.
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Maternal prenatal depressive symptoms, nicotine addiction, and smoking-related knowledge, attitudes, beliefs, and behaviors.
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Maternal tobacco smoking, nicotine replacement and neurobehavioural development.
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Mecamylamine acutely increases human intravenous nicotine self-administration.
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Mecamylamine combined with nicotine skin patch facilitates smoking cessation beyond nicotine patch treatment alone.
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Mecamylamine increases cigarette smoking in psychiatric patients.
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Mecamylamine increases nicotine preference and attenuates nicotine discrimination.
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Menthol decreases oral nicotine aversion in C57BL/6 mice through a TRPM8-dependent mechanism.
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Menthol disrupts nicotine's psychostimulant properties in an age and sex-dependent manner in C57BL/6J mice.
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Menthol preference moderates the relationship between cigarette nicotine content choice and reactions in young adults who smoke infrequently.
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Metallothionein expression and neurocognitive function in mice.
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Mimicking maternal smoking and pharmacotherapy of preterm labor: fetal nicotine exposure enhances the effect of late gestational dexamethasone treatment on noradrenergic circuits.
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Mimicking maternal smoking and pharmacotherapy of preterm labor: interactions of fetal nicotine and dexamethasone on serotonin and dopamine synaptic function in adolescence and adulthood.
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Mode of action: disruption of brain cell replication, second messenger, and neurotransmitter systems during development leading to cognitive dysfunction--developmental neurotoxicity of nicotine.
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Modeling adolescent nicotine exposure: effects on cholinergic systems in rat brain regions.
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Modeling the developmental neurotoxicity of nicotine in vitro: cell acquisition, growth and viability in PC12 cells.
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Modulation of cerebral microvascular permeability by endothelial nicotinic acetylcholine receptors.
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Molecular genetics of successful smoking cessation: convergent genome-wide association study results.
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Multiple brain pathways and receptors underlying tobacco addiction.
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Mutually augmenting interactions of dextromethorphan and sazetidine-A for reducing nicotine self-administration in rats.
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NIH electronic cigarette workshop: developing a research agenda.
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NMDA systems in the amygdala and piriform cortex and nicotinic effects on memory function.
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Naltrexone blockade of nicotine effects in cigarette smokers.
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National working conference on smoking and body weight. Task Force 2: Methods of assessment, strategies for research.
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Neonatal 6-hydroxydopamine lesions of the frontal cortex in rats: persisting effects on locomotor activity, learning and nicotine self-administration.
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Neuro-anatomic mapping of dopamine D1 receptor involvement in nicotine self-administration in rats.
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Neuroanatomical circuitry mediating the sensory impact of nicotine in the central nervous system.
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Neurobehavioral impairments caused by developmental imidacloprid exposure in zebrafish.
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New findings on nicotine addiction and treatment.
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Nicotine Withdrawal Induces Neural Deficits in Reward Processing.
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Nicotine activates TRPM5-dependent and independent taste pathways.
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Nicotine addiction and treatment.
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Nicotine administration in adolescence reprograms the subsequent response to nicotine treatment and withdrawal in adulthood: sex-selective effects on cerebrocortical serotonergic function.
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Nicotine and attention in adult attention deficit hyperactivity disorder (ADHD).
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Nicotine and clozapine actions on pre-pulse inhibition deficits caused by N-methyl-D-aspartate (NMDA) glutamatergic receptor blockade.
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Nicotine and clozapine effects on attentional performance impaired by the NMDA antagonist dizocilpine in female rats.
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Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells.
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Nicotine and non-nicotine smoking factors differentially modulate craving, withdrawal and cerebral blood flow as measured with arterial spin labeling.
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Nicotine and nonnicotine factors in cigarette addiction.
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Nicotine and the adolescent brain: insights from an animal model.
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Nicotine as a therapeutic drug.
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Nicotine decreases bradykinesia-rigidity in haloperidol-treated patients with schizophrenia.
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Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain.
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Nicotine deprivation influences P300 markers of cognitive control.
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Nicotine does not enhance tumorigenesis in mutant K-ras-driven mouse models of lung cancer.
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Nicotine effects on adults with attention-deficit/hyperactivity disorder.
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Nicotine effects on learning in zebrafish: the role of dopaminergic systems.
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Nicotine enhances stimulus detection performance of middle- and old-aged rats: a longitudinal study.
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Nicotine evokes cell death in embryonic rat brain during neurulation.
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Nicotine exposure in adolescence alters the response of serotonin systems to nicotine administered subsequently in adulthood.
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Nicotine for postoperative analgesia: a systematic review and meta-analysis.
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Nicotine increases anterior insula activation to expected and unexpected outcomes among nonsmokers.
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Nicotine increases in vivo blood-brain barrier permeability and alters cerebral microvascular tight junction protein distribution.
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Nicotine increases size and severity of experimental choroidal neovascularization.
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Nicotine inhibits voltage-dependent sodium channels and sensitizes vanilloid receptors.
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Nicotine interactions with haloperidol, clozapine and risperidone and working memory function in rats.
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Nicotine interactions with low-dose alcohol: pharmacological influences on smoking and drinking motivation.
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Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos.
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Nicotine is a neurotoxin in the adolescent brain: critical periods, patterns of exposure, regional selectivity, and dose thresholds for macromolecular alterations.
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Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes.
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Nicotine preference increases after cigarette deprivation.
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Nicotine preloading: the importance of a pre-cessation reduction in smoking behavior.
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Nicotine replacement and behavioral therapy for smoking cessation in pregnancy.
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Nicotine self-administration in animals and humans: similarities and differences.
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Nicotine skin patch treatment and adverse reactions: skin irritation, skin sensitization, and nicotine as a hapten.
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Nicotine skin patch treatment increases abstinence, decreases withdrawal symptoms, and attenuates rewarding effects of smoking.
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Nicotine therapy in adulthood reverses the synaptic and behavioral deficits elicited by prenatal exposure to phenobarbital.
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Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial.
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Nicotine withdrawal modulates frontal brain function during an affective Stroop task.
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Nicotine-alcohol interactions and attentional performance on an operant visual signal detection task in female rats.
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Nicotine-alcohol interactions and cognitive function in rats.
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Nicotine-antipsychotic drug interactions and attentional performance in female rats.
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Nicotine-dizocilpine interactions and working and reference memory performance of rats in the radial-arm maze.
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Nicotine-haloperidol interactions and cognitive performance in schizophrenics.
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Nicotine-mecamylamine treatment for smoking cessation: the role of pre-cessation therapy.
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Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation.
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Nicotinic acetylcholine receptor expression and susceptibility to cholinergic immunomodulation in human monocytes of smoking individuals.
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Nicotinic acetylcholine receptor stimulation impairs epidermal permeability barrier function and recovery and modulates cornified envelope proteins.
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Nicotinic alpha7- or beta2-containing receptor knockout: effects on radial-arm maze learning and long-term nicotine consumption in mice.
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Nicotinic and muscarinic interactions and choice accuracy in the radial-arm maze.
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Nicotinic antagonist effects in the mediodorsal thalamic nucleus: regional heterogeneity of nicotinic receptor involvement in cognitive function.
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Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin.
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Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo.
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Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization.
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Nicotinic interactions with antipsychotic drugs, models of schizophrenia and impacts on cognitive function.
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Nicotinic involvement in memory function in zebrafish.
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Nicotinic receptor subtypes and cognitive function.
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Nicotinic receptors in the habenula: importance for memory.
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Nicotinic stimulation of splenic T cells is protective in endoscopic retrograde cholangiopancreatography-induced acute pancreatitis in mice.
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Nicotinic system involvement in Alzheimer's and Parkinson's diseases. Implications for therapeutics.
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Nicotinic systems and cognitive function.
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Nicotinic, muscarinic and dopaminergic actions in the ventral hippocampus and the nucleus accumbens: effects on spatial working memory in rats.
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Nicotinic-antipsychotic drug interactions and cognitive function.
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Nicotinic-glutamatergic interactions and attentional performance on an operant visual signal detection task in female rats.
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Nicotinic-serotonergic drug interactions and attentional performance in rats.
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Non-neurogenic adrenal catecholamine release in the neonatal rat: exocytosis or diffusion?
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Novel rapid-acting sublingual nicotine tablet as a cigarette substitution strategy.
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Olanzapine interactions with nicotine and mecamylamine in rats: effects on memory function.
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Olfactory cue reactivity in nicotine-dependent adult smokers.
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Oral nicotine solution for smoking cessation: a pilot tolerability study.
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Oral sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, reduces nicotine self-administration in rats.
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Ornithine decarboxylase in developing rat heart and brain: role of sympathetic development for responses to autonomic stimulants and the effects of reserpine on maturation.
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Outcomes from an outpatient smoking-cessation clinic.
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Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos.
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PET studies of the influences of nicotine on neural systems in cigarette smokers.
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Parasympathetic stimulation via the vagus nerve prevents systemic organ dysfunction by abrogating gut injury and lymph toxicity in trauma and hemorrhagic shock.
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Paternal nicotine exposure in rats produces long-lasting neurobehavioral effects in the offspring.
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Perceived nicotine content of reduced nicotine content cigarettes is a correlate of perceived health risks.
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Pergolide interactions with nicotine and pilocarpine in rats on the radial-arm maze.
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Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain.
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Permanent, sex-selective effects of prenatal or adolescent nicotine exposure, separately or sequentially, in rat brain regions: indices of cholinergic and serotonergic synaptic function, cell signaling, and neural cell number and size at 6 months of age.
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Persistence of chronic nicotine-induced cognitive facilitation.
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Persistent and delayed behavioral changes after nicotine treatment in adolescent rats.
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Persistent attenuation of nicotine self-administration in rats by co-administration of chronic nicotine infusion with the dopamine D1 receptor antagonist SCH-23390 or the serotonin 5-HT2C agonist lorcaserin.
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Persistent c-fos induction by nicotine in developing rat brain regions: interaction with hypoxia.
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Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
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Pharmacologic and sensorimotor components of satiation in cigarette smoking.
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Platelet monoamine oxidase, smoking cessation, and tobacco withdrawal symptoms.
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Potentiation of nicotine reward by alcohol.
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Practice guideline for the treatment of patients with nicotine dependence. American Psychiatric Association.
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Pre-cessation varenicline treatment vs post-cessation NRT: an uneven playing field.
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Precessation treatment with nicotine patch significantly increases abstinence rates relative to conventional treatment.
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Precessation treatment with nicotine skin patch facilitates smoking cessation.
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Preliminary Evaluation of Short-Term Abstinence Effects Among Never-Smoking Experienced Users of Modern Electronic Cigarettes.
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Preliminary findings from a clinical demonstration project for veterans returning from Iraq or Afghanistan.
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Prenatal cocaine and/or nicotine exposure in rats: preliminary findings on long-term cognitive outcome and genital development at birth.
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Prenatal drug exposures sensitize noradrenergic circuits to subsequent disruption by chlorpyrifos.
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Prenatal exposure to nicotine impairs nervous system development at a dose which does not affect viability or growth.
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Prenatal exposure to nicotine via maternal infusions: effects on development of catecholamine systems.
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Prenatal nicotine alters the developmental neurotoxicity of postnatal chlorpyrifos directed toward cholinergic systems: better, worse, or just "different?".
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Prenatal nicotine changes the response to postnatal chlorpyrifos: Interactions targeting serotonergic synaptic function and cognition.
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Prenatal nicotine effects on memory in rats: pharmacological and behavioral challenges.
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Prenatal nicotine exposure alters the response to nicotine administration in adolescence: effects on cholinergic systems during exposure and withdrawal.
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Prenatal nicotine exposure alters the responses to subsequent nicotine administration and withdrawal in adolescence: Serotonin receptors and cell signaling.
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Prenatal nicotine exposure and cognitive performance in rats.
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Prenatal nicotine exposure evokes alterations of cell structure in hippocampus and somatosensory cortex.
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Prenatal nicotine exposure impairs beta-adrenergic function: persistent chronotropic subsensitivity despite recovery from deficits in receptor binding.
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Prenatal nicotine exposure in rhesus monkeys compromises development of brainstem and cardiac monoamine pathways involved in perinatal adaptation and sudden infant death syndrome: amelioration by vitamin C.
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Presynaptic and postsynaptic contributions to ontogeny of sympathetic control of heart rate in the pre-weanling rat.
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Prevalence, Trends, and Distribution of Nicotine and Marijuana use in E-cigarettes among US adults: The Behavioral Risk Factor Surveillance System 2016-2018.
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Prolonged nicotine patch use in quitters with past abstinence-induced depressed mood.
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Prolonging the Reduction of Nicotine Self-Administration in Rats by Coadministering Chronic Nicotine With Amitifadine, a Triple Monoamine Reuptake Inhibitor With CYP2B6 Inhibitory Actions.
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Psychopharmacological interactions between nicotine and ethanol.
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Psychophysiological interactions between caffeine and nicotine.
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Public health clinical demonstration project for smoking cessation in american veterans who served since september 11, 2001.
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Public health clinical demonstration project for smoking cessation in veterans with posttraumatic stress disorder.
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Pulmonary delivery of nicotine pyruvate: sensory and pharmacokinetic characteristics.
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Randomized Trial of Reduced-Nicotine Standards for Cigarettes.
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Randomized trial comparing mindfulness training for smokers to a matched control.
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Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells.
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Rapid Brain Nicotine Uptake from Electronic Cigarettes.
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Reactions to reduced nicotine content cigarettes in a sample of young adult, low-frequency smokers.
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Reducing nicotine exposure results in weight gain in smokers randomised to very low nicotine content cigarettes.
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Reduction of nicotine self-administration by chronic nicotine infusion with H1 histamine blockade in female rats.
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Refined cigarette smoke as a method for reducing nicotine intake.
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Reinforcing effects of nicotine and non-nicotine components of cigarette smoke.
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Relationships between the Nicotine Metabolite Ratio and a Panel of Exposure and Effect Biomarkers: Findings from Two Studies of U.S. Commercial Cigarette Smokers.
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Responses to Gradual and Immediate Reduction of Nicotine in Cigarettes in Young Versus Older Adult Smokers.
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Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by nicotine administration and neural stem cell transplantation.
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Reversal of clozapine effects on working memory in rats with fimbria-fornix lesions.
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Role of insular cortex D₁ and D₂ dopamine receptors in nicotine self-administration in rats.
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Role of nicotine dose and sensory cues in the regulation of smoke intake.
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Role of nicotinic receptors in the lateral habenula in the attenuation of amphetamine-induced prepulse inhibition deficits of the acoustic startle response in rats.
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Safety and effectiveness of transdermal nicotine patch in smokers admitted with acute coronary syndromes.
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Saliva nicotine as an index of plasma levels in nicotine skin patch users.
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Sazetidine-A, a selective alpha4beta2 nicotinic receptor desensitizing agent and partial agonist, reduces nicotine self-administration in rats.
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Selectively reduced responses to smoking cues in amygdala following extinction-based smoking cessation: results of a preliminary functional magnetic resonance imaging study.
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Selectivity of lingual nerve fibers to chemical stimuli.
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Self-administration by female rats of low doses of nicotine alone vs. nicotine in tobacco smoke extract.
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Sensorimotor deficits and increased brain nicotinic acetylcholine receptors following exposure to chlorpyrifos and/or nicotine in rats.
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Separate or sequential exposure to nicotine prenatally and in adulthood: persistent effects on acetylcholine systems in rat brain regions.
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Sertraline attenuates hyperphagia in rats following nicotine withdrawal.
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Sex differences in response to nicotine in C57Bl/6:129SvEv mice.
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Sex-selective hippocampal alterations after adolescent nicotine administration: effects on neurospecific proteins.
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Sex-specific effects of cigarette mentholation on brain nicotine accumulation and smoking behavior.
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Short-term adolescent nicotine exposure has immediate and persistent effects on cholinergic systems: critical periods, patterns of exposure, dose thresholds.
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Short-term adolescent nicotine exposure in rats elicits immediate and delayed deficits in T-lymphocyte function: critical periods, patterns of exposure, dose thresholds.
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Should managed care organizations pay for nicotine replacement therapy?
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Silver acetate interactions with nicotine and non-nicotine smoke components.
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Smoking Status, Nicotine Medication, Vaccination, and COVID-19 Hospital Outcomes: Findings from the COVID EHR Cohort at the University of Wisconsin (CEC-UW) Study.
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Smoking abstinence and cessation-related outcomes one month after an immediate versus gradual reduction in nicotine content of cigarettes.
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Smoking abstinence and neurocognition: implications for cessation and relapse.
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Smoking and anxiety in combat veterans with chronic posttraumatic stress disorder: a review.
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Smoking and ischemic stroke: a role for nicotine?
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Smoking and therapeutic response to clozapine in patients with schizophrenia.
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Smoking quit success genotype score predicts quit success and distinct patterns of developmental involvement with common addictive substances.
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Smoking withdrawal shifts the spatiotemporal dynamics of neurocognition.
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Smoking withdrawal symptoms in response to a trauma-related stressor among Vietnam combat veterans with posttraumatic stress disorder.
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Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin.
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Strain-specific altered nicotine metabolism in 3,3'-diindolylmethane (DIM) exposed mice.
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Stress alleviation and reward enhancement: two promising targets for relapse prevention.
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Sub-anesthetic doses of ketamine attenuate nicotine self-administration in rats.
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Subchronic effects of plant alkaloids on anxiety-like behavior in zebrafish.
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Sugars and Sweeteners in Tobacco and Nicotine Products: Food and Drug Administration's Regulatory Implications.
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Supplemental nicotine preloading for smoking cessation in posttraumatic stress disorder: Results from a randomized controlled trial.
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Support for a nicotine reduction policy among participants enrolled in a 20-week trial of very low nicotine content cigarettes.
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Symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior.
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Synthetic nicotine has arrived.
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Taste-specific neuronal ensembles in the gustatory cortex of awake rats.
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Teratogenic, bioenergetic, and behavioral effects of exposure to total particulate matter on early development of zebrafish (Danio rerio) are not mimicked by nicotine.
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The Agency for Health Care Policy and Research Smoking Cessation Clinical Practice Guideline.
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The Developmental Neurotoxicity of Tobacco Smoke Can Be Mimicked by a Combination of Nicotine and Benzo[a]Pyrene: Effects on Cholinergic and Serotonergic Systems.
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The E-cigarette or Vaping Product Use-Associated Lung Injury Epidemic: Pathogenesis, Management, and Future Directions: An Official American Thoracic Society Workshop Report.
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The Effects of Nicotine and Tobacco Use on Brain Reward Function: Interaction With Nicotine Dependence Severity.
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The Impact of Gradual and Immediate Nicotine Reduction on Subjective Cigarette Ratings.
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The Tobacco 21 Movement and Electronic Nicotine Delivery System Use Among Youth.
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The biology of tobacco and nicotine: bench to bedside.
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The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans.
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The effect of cigarette smoke extract on trophoblast cell viability and migration: the role of adrenomedullin.
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The effect of nicotine and trauma context on acoustic startle in smokers with and without posttraumatic stress disorder.
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The effect of nicotine on the delay of gastric emptying.
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The effects of nicotine and non-nicotine smoking factors on working memory and associated brain function.
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The effects of nicotine on vascular smooth muscle cell chemotaxis induced by thrombospondin-1 and fibronectin.
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The fMRI BOLD response to unisensory and multisensory smoking cues in nicotine-dependent adults.
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The importance of nicotinic acetylcholine receptors in schizophrenia, bipolar disorder and Tourette's syndrome.
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The long-term effects of prenatal nicotine exposure on neurologic development.
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The marketing of dissolvable tobacco: social science and public policy research needs.
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The nicotine patch in smoking cessation. A randomized trial with telephone counseling.
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The role of alpha7 and alpha4beta2 nicotinic receptors in the nicotine-induced anxiolytic effect in zebrafish.
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The role of upper airway stimulation in smoking.
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The safety of transdermal nicotine as an aid to smoking cessation in patients with cardiac disease.
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The use of flavor in cigarette substitutes.
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This is your teen brain on drugs: In search of biological factors unique to dependence toxicity in adolescence.
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Threshold of adulthood for the onset of nicotine self-administration in male and female rats.
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Thymocytes and cultured thymic epithelial cells express transcripts encoding alpha-3, alpha-5, and beta-4 subunits of neuronal nicotinic acetylcholine receptors. Preferential transcription of the alpha-3 and beta-4 genes by immature CD4+8+ thymocytes and evidence for response to nicotine in thymocytes.
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Time-dependent effects of nicotine on reversal of dizocilpine-induced attentional impairment in female rats.
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Timing of nicotine effects on learning in zebrafish.
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Tobacco Withdrawal Symptoms Before and After Nicotine Deprivation in Veteran Smokers with Posttraumatic Stress Disorder and with Major Depressive Disorder.
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Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells.
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Transcranial Direct Current Stimulation Applied to the Dorsolateral and Ventromedial Prefrontal Cortices in Smokers Modifies Cognitive Circuits Implicated in the Nicotine Withdrawal Syndrome.
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Transdermal administration of nicotine.
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Transdermal nicotine attenuates depression symptoms in nonsmokers: a double-blind, placebo-controlled trial.
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Transdermal nicotine effects on attention.
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Transdermal nicotine facilitates smoking cessation.
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Transdermal nicotine for analgesia after radical retropubic prostatectomy.
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Transdermal nicotine reduces cigarette craving and nicotine preference.
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Transdermal nicotine replacement in pregnancy: maternal pharmacokinetics and fetal effects.
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Twenty-Four-Hour Cardiovascular Effects of Electronic Cigarettes Compared With Cigarette Smoking in Dual Users.
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Validation of an extracerebral reference region approach for the quantification of brain nicotinic acetylcholine receptors in squirrel monkeys with PET and 2-18F-fluoro-A-85380.
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Ventral hippocampal NMDA blockade and nicotinic effects on memory function.
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Ventral hippocampal alpha 7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze.
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Ventral hippocampal alpha4beta2 nicotinic receptors and chronic nicotine effects on memory.
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Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats.
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Ventral hippocampal ibotenic acid lesions block chronic nicotine-induced spatial working memory improvement in rats.
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Very Low Nicotine Content Cigarettes Disrupt the Feedback Loop of Affective States and Smoking Behavior.
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Whether to push or pull? Nicotine reduction and non-combusted alternatives - Two strategies for reducing smoking and improving public health.
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Working memory performance and cholinergic effects in the ventral tegmental area and substantia nigra.
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Young adult dual combusted cigarette and e-cigarette users' anticipated responses to a nicotine reduction policy and menthol ban in combusted cigarettes.
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Zebrafish assessment of cognitive improvement and anxiolysis: filling the gap between in vitro and rodent models for drug development.
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Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficits.
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alpha7 Nicotinic acetylcholine receptors and temporal memory: synergistic effects of combining prenatal choline and nicotine on reinforcement-induced resetting of an interval clock.
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Keywords of People
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Dedert, Eric,
Associate Professor in Psychiatry and Behavioral Sciences,
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
-
Jabba, Sairam V.,
Research Scientist,
Anesthesiology
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McClernon, F Joseph,
Professor in Psychiatry and Behavioral Sciences,
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
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Oliver, Jason A,
Adjunct Assistant Professor in the Department of Psychiatry and Behavioral Sciences,
Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychology
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Rubenstein, Dana,
Student,
Psychiatry & Behavioral Sciences
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Schwartz-Bloom, Rochelle D.,
Professor Emeritus of Pharmacology & Cancer Biology,
Duke Science & Society
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Turkington, Timothy Garvey,
Associate Professor in Radiology,
Radiology