Nipecotic Acids

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  Subject Areas on Research

  • An inducible heat shock protein 70 small molecule inhibitor demonstrates anti-dengue virus activity, validating Hsp70 as a host antiviral target. 
  • GABA transport modulates the ethanol sensitivity of tonic inhibition in the rat dentate gyrus. 
  • Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70. 
  • Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress. 
  • Postischemic inhibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus. 
  • The efficacy and tolerability of tiagabine in adult patients with post-traumatic stress disorder. 
  • The sleep effects of tiagabine on the first night of treatment predict post-traumatic stress disorder response at three weeks. 
  • Tiagabine for posttraumatic stress disorder: effects of open-label and double-blind discontinuation treatment. 
  • Tiagabine in treatment refractory bipolar disorder: a clinical case series. 
  • Tiagabine increases slow-wave sleep in a dose-dependent fashion without affecting traditional efficacy measures in adults with primary insomnia. 
  • Trauma, resilience and saliostasis: effects of treatment in post-traumatic stress disorder.