Nitrates

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  Subject Areas on Research

  • 13N,15N isotope and kinetic evidence against hyponitrite as an intermediate in dentrification. 
  • A controlled trial of acute effects of human exposure to traffic particles on pulmonary oxidative stress and heart rate variability. 
  • A novel inhaled organic nitrate that affects pulmonary vascular tone in a piglet model of hypoxia-induced pulmonary hypertension. 
  • A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. 
  • A suite of microplate reader-based colorimetric methods to quantify ammonium, nitrate, orthophosphate and silicate concentrations for aquatic nutrient monitoring. 
  • Activation of EGF receptors mediates pulmonary vasoconstriction induced by residual oil fly ash. 
  • Age-dependent augmentation of cardiac endothelial NOS in a genetic rat model of heart failure. 
  • Algal blooms and the nitrogen-enrichment hypothesis in Florida springs: evidence, alternatives, and adaptive management. 
  • An apoptotic model for nitrosative stress. 
  • Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia. 
  • Application of ion trap-MS with H/D exchange and QqTOF-MS in the identification of microbial degradates of trimethoprim in nitrifying activated sludge. 
  • Assessment of baroreflex control from beat-to-beat blood pressure and heart rate changes: a validation study. 
  • Association of Ozone Exposure With Cardiorespiratory Pathophysiologic Mechanisms in Healthy Adults. 
  • CLINICAL PRACTICE. Chronic Stable Angina. 
  • Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants. 
  • Circulating markers of inflammation and endothelial function, and their relationship to diabetic retinopathy. 
  • Circulating tetrahydrobiopterin concentrations in patients with septic shock. 
  • Contributions of endothelial and neuronal nitric oxide synthases to cerebrovascular responses to hyperoxia. 
  • Contributions of hemodynamic monitoring to the treatment of chronic congestive heart failure. 
  • Cross-talk Between Nitrate-Nitrite-NO and NO Synthase Pathways in Control of Vascular NO Homeostasis. 
  • Demographics, clinical characteristics, and outcomes of patients hospitalized for decompensated heart failure: observations from the IMPACT-HF registry. 
  • Diagnostic and therapeutic challenges. 
  • Dietary nitrate attenuates renal ischemia-reperfusion injuries by modulation of immune responses and reduction of oxidative stress. 
  • Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease. 
  • Differential effects of nitric oxide-mediated S-nitrosylation on p50 and c-jun DNA binding. 
  • Diversity and detection of nitrate assimilation genes in marine bacteria. 
  • Dose dependent effects of nitrate supplementation on cardiovascular control and microvascular oxygenation dynamics in healthy rats. 
  • Drought-induced saltwater incursion leads to increased wetland nitrogen export. 
  • Effect of inhibitors of arachidonic acid metabolism on corneal neovascularization in the rat. 
  • Effects of nitrate supplementation via beetroot juice on contracting rat skeletal muscle microvascular oxygen pressure dynamics. 
  • Endogenous protein S-Nitrosylation in E. coli: regulation by OxyR. 
  • Endothelial nitric oxide synthase increases in left atria of dogs with pacing-induced heart failure. 
  • Fine particle components and health--a systematic review and meta-analysis of epidemiological time series studies of daily mortality and hospital admissions. 
  • Genomes and gene expression across light and productivity gradients in eastern subtropical Pacific microbial communities. 
  • Give and Take: A Watershed Acid Rain Mitigation Experiment Increases Baseflow Nitrogen Retention but Increases Stormflow Nitrogen Export. 
  • Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes. 
  • Hepatic sulfite oxidase. Effect of anions on interaction with cytochrome c. 
  • Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate. 
  • Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. 
  • Hyperbaric oxygen reduces cerebral blood flow by inactivating nitric oxide. 
  • Hypoxia inhibits nitric oxide synthesis in isolated rabbit lung. 
  • INDIE-HFpEF (Inorganic Nitrite Delivery to Improve Exercise Capacity in Heart Failure With Preserved Ejection Fraction): Rationale and Design. 
  • INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) Profiling Identifies Ambulatory Patients at High Risk on Medical Therapy After Hospitalizations for Heart Failure. 
  • Impact of dietary nitrate supplementation via beetroot juice on exercising muscle vascular control in rats. 
  • In situ activity of a dominant Prochlorococcus ecotype (eHL-II) from rRNA content and cell size. 
  • In-stream uptake dampens effects of major forest disturbance on watershed nitrogen export. 
  • Inducible nitric oxide synthase expression by peritoneal macrophages in endometriosis-associated infertility. 
  • Inhaled nitric oxide therapy increases blood nitrite, nitrate, and s-nitrosohemoglobin concentrations in infants with pulmonary hypertension. 
  • Interlaboratory validation of a new assay for DNA-protein crosslinks. 
  • Intraperitoneal fluid neopterin, nitrate, and tryptophan after regional administration of interleukin-12. 
  • Invasion, competitive dominance, and resource use by exotic and native California grassland species. 
  • Invasive species' leaf traits and dissimilarity from natives shape their impact on nitrogen cycling: a meta-analysis. 
  • Investigations into the role of sulfhydryl groups in the mechanism of action of the nitrates. 
  • Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. 
  • Mechanism of covalent modification of glyceraldehyde-3-phosphate dehydrogenase at its active site thiol by nitric oxide, peroxynitrite and related nitrosating agents. 
  • Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease. 
  • Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages. 
  • Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA. 
  • NADPH oxidase in the renal microvasculature is a primary target for blood pressure-lowering effects by inorganic nitrate and nitrite. 
  • NF-kappaB, inflammation and pancreatic carcinogenesis: NF-kappaB as a chemoprevention target (review). 
  • NanoSIMS single cell analyses reveal the contrasting nitrogen sources for small phytoplankton. 
  • Niche partitioning among Prochlorococcus ecotypes along ocean-scale environmental gradients. 
  • Nitrate levels in malaria. 
  • Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons. 
  • Nitration of tyrosine by hydrogen peroxide and nitrite. 
  • Nitric oxide as an inflammatory mediator in autoimmune MRL-lpr/lpr mice. 
  • Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression. 
  • Nitric oxide in the central nervous system. 
  • Nitric oxide modulates excitation-contraction coupling in the diaphragm. 
  • Nitric oxide synthase type 2 promoter polymorphisms, nitric oxide production, and disease severity in Tanzanian children with malaria. 
  • Normative values for exhaled breath condensate pH and its relationship to exhaled nitric oxide in healthy African Americans. 
  • Nutrient profiles in the everglades: examination along the eutrophication gradient. 
  • O=O NO: it's CO. 
  • On the complementary relationship between marginal nitrogen and water-use efficiencies among Pinus taeda leaves grown under ambient and CO2-enriched environments. 
  • Organ uptake and release of inorganic nitrate and nitrite in the pig. 
  • Organic nitrogen uptake of Scots pine seedlings is independent of current carbohydrate supply. 
  • Outcome in medically treated coronary artery disease. Ischemic events: nonfatal infarction and death. 
  • Perchlorate reduction by autotrophic bacteria attached to zerovalent iron in a flow-through reactor. 
  • Perchlorate reduction by autotrophic bacteria in the presence of zero-valent iron. 
  • Peroxynitrite formation and decreased catalase activity in autoimmune MRL-lpr/lpr mice. 
  • Peroxynitrite-induced rat colitis--a new model of colonic inflammation. 
  • Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production. 
  • Pharmacological and emerging therapies in the treatment of chronic angina. 
  • Pharmacological treatment of elderly patients with acute coronary syndromes without persistent ST segment elevation. 
  • Plasma des-acyl ghrelin, but not plasma HMW adiponectin, is a useful cardiometabolic marker for predicting atherosclerosis in elderly hypertensive patients. 
  • Plasma nitrite and nitrate levels as a noninvasive marker of pathology after human small bowel transplantation. 
  • Precipitation and growth of zinc sulfide nanoparticles in the presence of thiol-containing natural organic ligands. 
  • Probing the catalytic mechanism of sulfite reductase by X-ray crystallography: structures of the Escherichia coli hemoprotein in complex with substrates, inhibitors, intermediates, and products. 
  • Prochlorococcus: approved for export. 
  • Protein S-nitrosylation in health and disease: a current perspective. 
  • Psychosocial and physical predictors of anginal pain relief with medical management. 
  • Quality of life after coronary angioplasty or continued medical treatment for angina: three-year follow-up in the RITA-2 trial. Randomized Intervention Treatment of Angina. 
  • Regional cerebral blood flow changes associated with amyl nitrite inhalation. 
  • Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions. 
  • S-nitrosoglutathione reductase: an important regulator in human asthma. 
  • S-nitrosylation: physiological regulation of NF-kappaB. 
  • Safety of nifedipine in angina pectoris: a meta-analysis. 
  • Seeps regulate stream nitrate concentration in a forested Appalachian catchment. 
  • Similar but not the same: normobaric and hyperbaric pulmonary oxygen toxicity, the role of nitric oxide. 
  • Sources and transformations of nitrogen compounds along the Lower Jordan River. 
  • Sources of salinity in ground water from Jericho area, Jordan Valley. 
  • Southern Ocean iron enrichment experiment: carbon cycling in high- and low-Si waters. 
  • Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia. 
  • The antiplatelet effects of organic nitrates and related nitroso compounds in vitro and in vivo and their relevance to cardiovascular disorders. 
  • The effect of advection on the nutrient reservoir in the North Atlantic subtropical gyre. 
  • The effect of angiostatic steroids and beta-cyclodextrin tetradecasulfate on corneal neovascularization in the rat. 
  • The nature of treatment selection in coronary artery disease. Experience with medical and surgical treatment of a chronic disease. 
  • The pharmacology of aminoadamantane nitrates. 
  • The pterin of the molybdenum cofactor. 
  • The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine. 
  • Thermodynamic constraints on the utility of ecological stoichiometry for explaining global biogeochemical patterns. 
  • Tolerance to organic nitrates: clinical and experimental perspectives. 
  • Trabodenoson, an Adenosine Mimetic With A1 Receptor Selectivity Lowers Intraocular Pressure by Increasing Conventional Outflow Facility in Mice. 
  • UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation. 
  • Unstable angina pectoris: National Cooperative Study Group to Compare Surgical and Medical Therapy. 
  • Use of evidence-based medical therapy in patients undergoing percutaneous coronary revascularization in the United States, Europe, and Canada. Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT-I) and Canadian Coronary Atherectomy Trial (CCAT) investigators. 
  • Vasodilators in the treatment of acute heart failure: what we know, what we don't. 
  • Watershed urbanization alters the composition and function of stream bacterial communities. 
  • cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation. 
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  Keywords of People

  • Hsu-Kim, Heileen, Professor in the Department of Civil and Environmental Engineering, Civil and Environmental Engineering
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. / Guidant Foundation Distinguished Professor of Cardiology, Medicine, Clinical Pharmacology
  • Starmer, Charles Franklin, Professor Emeritus of Computer Science, Computer Science