Nitrites

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  Subject Areas on Research

  • 13N,15N isotope and kinetic evidence against hyponitrite as an intermediate in dentrification. 
  • A controlled trial of acute effects of human exposure to traffic particles on pulmonary oxidative stress and heart rate variability. 
  • A method to attenuate pneumoperitoneum-induced reductions in splanchnic blood flow. 
  • A nitric oxide processing defect of red blood cells created by hypoxia: deficiency of S-nitrosohemoglobin in pulmonary hypertension. 
  • Activated conformers of Escherichia coli sulfite reductase heme protein subunit. 
  • Activation of EGF receptors mediates pulmonary vasoconstriction induced by residual oil fly ash. 
  • Age-dependent augmentation of cardiac endothelial NOS in a genetic rat model of heart failure. 
  • An S-nitrosothiol (SNO) synthase function of hemoglobin that utilizes nitrite as a substrate. 
  • An apoptotic model for nitrosative stress. 
  • Androgen-mediated immune function is altered by the apolipoprotein E gene. 
  • Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia. 
  • Apolipoprotein E isoform mediated regulation of nitric oxide release. 
  • Assessments of the chemistry and vasodilatory activity of nitrite with hemoglobin under physiologically relevant conditions. 
  • Association of Ozone Exposure With Cardiorespiratory Pathophysiologic Mechanisms in Healthy Adults. 
  • Association of air pollution sources and aldehydes with biomarkers of blood coagulation, pulmonary inflammation, and systemic oxidative stress. 
  • Characterization of NO and cytokine production in immune-activated microglia and peritoneal macrophages derived from a mouse model expressing the human NOS2 gene on a mouse NOS2 knockout background. 
  • Characterization of complexes between Escherichia coli sulfite reductase hemoprotein subunit and its substrates sulfite and nitrite. 
  • Contributions of endothelial and neuronal nitric oxide synthases to cerebrovascular responses to hyperoxia. 
  • Controlled exposure to diesel exhaust causes increased nitrite in exhaled breath condensate among subjects with asthma. 
  • Cross-talk Between Nitrate-Nitrite-NO and NO Synthase Pathways in Control of Vascular NO Homeostasis. 
  • Diabetes status differentiates endothelial function and plasma nitrite response to exercise stress in peripheral arterial disease following supervised training. 
  • Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease. 
  • EPR spectroscopy of nitrite complexes of methemoglobin. 
  • Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial. 
  • Effect of low versus high dialysate sodium concentration on blood pressure and endothelial-derived vasoregulators during hemodialysis: a randomized crossover study. 
  • Efficacy of ethyl nitrite in reversing surgical vasospasm. 
  • Endogenous protein S-Nitrosylation in E. coli: regulation by OxyR. 
  • Endothelial nitric oxide synthase increases in left atria of dogs with pacing-induced heart failure. 
  • Extreme differences between hemoglobins I and II of the clam Lucina pectinalis in their reactions with nitrite. 
  • Fas-induced caspase denitrosylation. 
  • Further evidence for distinct reactive intermediates from nitroxyl and peroxynitrite: effects of buffer composition on the chemistry of Angeli's salt and synthetic peroxynitrite. 
  • Hemoglobin and nitric oxide. 
  • Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate. 
  • Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. 
  • Hyperbaric oxygen reduces cerebral blood flow by inactivating nitric oxide. 
  • Hypoxia inhibits nitric oxide synthesis in isolated rabbit lung. 
  • Hypoxic vasodilation by red blood cells: evidence for an s-nitrosothiol-based signal. 
  • Impacts of silver nanoparticle coating on the nitrification potential of Nitrosomonas europaea. 
  • In situ activity of a dominant Prochlorococcus ecotype (eHL-II) from rRNA content and cell size. 
  • Inclusion of a nitric oxide congener in the insufflation gas repletes S-nitrosohemoglobin and stabilizes physiologic status during prolonged carbon dioxide pneumoperitoneum. 
  • Inclusion of an S-nitrosylating agent in the insufflating gas does not alter gastric activity in rats following pneumoperitoneum. 
  • Inducible nitric oxide synthase expression by peritoneal macrophages in endometriosis-associated infertility. 
  • Inhaled ethyl nitrite gas for persistent pulmonary hypertension in infants. 
  • Inhaled ethyl nitrite gas for persistent pulmonary hypertension of the newborn. 
  • Inhaled ethyl nitrite prevents hyperoxia-impaired postnatal alveolar development in newborn rats. 
  • Inhaled nitric oxide therapy increases blood nitrite, nitrate, and s-nitrosohemoglobin concentrations in infants with pulmonary hypertension. 
  • Inorganic nitrite attenuates NADPH oxidase-derived superoxide generation in activated macrophages via a nitric oxide-dependent mechanism. 
  • Late-outgrowth endothelial progenitors from patients with coronary artery disease: endothelialization of confluent stromal cell layers. 
  • Letter by Stamler et al Regarding Article, "Nitrite and S-Nitrosohemoglobin Exchange Across the Human Cerebral and Femoral Circulation: Relationship to Basal and Exercise Blood Flow Responses to Hypoxia". 
  • Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin. 
  • Location-dependent artifact for no measurement using multiwell plates. 
  • Lung epithelial cell-released nitric oxide protects against PMN-mediated cell injury. 
  • Magnetization of the sulfite and nitrite complexes of oxidized sulfite and nitrite reductases: EPR silent spin S = 1/2 states. 
  • Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. 
  • Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages. 
  • Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA. 
  • Mössbauer evidence for exchange-coupled siroheme and [4Fe-4S] prosthetic groups in Escherichia coli sulfite reductase. Studies of the reduced states and of a nitrite turnover complex. 
  • NADPH oxidase in the renal microvasculature is a primary target for blood pressure-lowering effects by inorganic nitrate and nitrite. 
  • Nitrate levels in malaria. 
  • Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression. 
  • Nitric oxide modulates excitation-contraction coupling in the diaphragm. 
  • Nitrite-methemoglobin inadequate for hypoxic vasodilation. 
  • Nitroxyl anion regulation of the NMDA receptor. 
  • Nonurban male homosexuals: epidemiologic, immunologic and virologic characteristics. 
  • Normative values for exhaled breath condensate pH and its relationship to exhaled nitric oxide in healthy African Americans. 
  • Nutrient profiles in the everglades: examination along the eutrophication gradient. 
  • On the reaction of ferric heme proteins with nitrite and sulfite. 
  • Organ uptake and release of inorganic nitrate and nitrite in the pig. 
  • Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production. 
  • Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage. 
  • Plant trait diversity buffers variability in denitrification potential over changes in season and soil conditions. 
  • Plasma des-acyl ghrelin, but not plasma HMW adiponectin, is a useful cardiometabolic marker for predicting atherosclerosis in elderly hypertensive patients. 
  • Plasma nitrite and nitrate levels as a noninvasive marker of pathology after human small bowel transplantation. 
  • Predicting urine culture results by dipstick testing and phase contrast microscopy. 
  • Probing the catalytic mechanism of sulfite reductase by X-ray crystallography: structures of the Escherichia coli hemoprotein in complex with substrates, inhibitors, intermediates, and products. 
  • Prochlorococcus: approved for export. 
  • Protection from lipopolysaccharide-induced lung injury by augmentation of airway S-nitrosothiols. 
  • Protection of perfused lung from oxidant injury by inhibitors of anion exchange. 
  • Removal of ammonia from contaminated air in a biotrickling filter - denitrifying bioreactor combination system. 
  • Repletion of S-nitrosohemoglobin improves organ function and physiological status in swine after brain death. 
  • Role of mitochondrial aldehyde dehydrogenase in nitroglycerin-induced vasodilation of coronary and systemic vessels: an intact canine model. 
  • Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions. 
  • S-Nitrosohemoglobin is unstable in the reductive erythrocyte environment and lacks O2/NO-linked allosteric function. 
  • S-nitrosoglutathione reductase: an important regulator in human asthma. 
  • S-nitrosylation in health and disease. 
  • Similar but not the same: normobaric and hyperbaric pulmonary oxygen toxicity, the role of nitric oxide. 
  • Siroheme: a new prosthetic group participating in six-electron reduction reactions catalyzed by both sulfite and nitrite reductases. 
  • Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia. 
  • The decomposition of thionitrites. 
  • The effects of static and intermittent compression on nitric oxide production in articular cartilage explants. 
  • The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine. 
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  Keywords of People

  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Innovation & Entrepreneurship
  • Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology