Norepinephrine

• 

  Subject Areas on Research

  • "Speed" warps time: methamphetamine's interactive roles in drug abuse, habit formation, and the biological clocks of circadian and interval timing. 
  • (3H)norepinephrine binding and lipolysis by isolated fat cells. 
  • (3H)norepinephrine binding: unrelated to catechol-O-methyl transferase. 
  • 3H-Dopamine uptake by synaptic storage vesicles of rat whole brain and brain regions. 
  • 6-hydroxydopamine destruction of central adrenergic neurones prevents or reverses developing DOCA-salt hypertension in rats. 
  • A comparison of the vasodilating effects of halothane and isoflurane on the isolated rabbit basilar artery with and without intact endothelium. 
  • A fraction of the ventricular myocardium that has the specificity of the cardiac beta-adrenergic receptor. 
  • A laboratory school comparison of mixed amphetamine salts extended release (Adderall XR) and atomoxetine (Strattera) in school-aged children with attention deficit/hyperactivity disorder. 
  • A new approach to the role of noradrenaline in learning: problem-solving in the marmoset after alpha-noradrenergic receptor blockade. 
  • A point mutation (D79N) of the alpha2A adrenergic receptor abolishes the antiepileptogenic action of endogenous norepinephrine. 
  • A randomized double-blinded multicenter comparison of remifentanil versus fentanyl when combined with isoflurane/propofol for early extubation in coronary artery bypass graft surgery. 
  • A.E. Bennett Research Award. Developmental traumatology. Part I: Biological stress systems. 
  • Abnormalities of cardiac sympathetic function in pacing-induced heart failure as assessed by [123I]metaiodobenzylguanidine scintigraphy. 
  • Absence of effect of cardiac denervation and induced right ventricular failure on canine myocardial norepinephrine binding sites. 
  • Activation and desensitization of beta-adrenergic receptor-coupled GTPase and adenylate cyclase of frog and turkey erythrocyte membranes. 
  • Activity of locus coeruleus neurons in amygdala kindled rats: role in the suppression of afterdischarge. 
  • Acute interleukin-6 administration does not impair muscle glucose uptake or whole-body glucose disposal in healthy humans. 
  • Adenosine 3',5'-monophosphate (cyclic AMP) as the mediator of the actions of melanocyte stimulating hormone (MSH) and norepinephrine on the frog skin. 
  • Adipocyte beta-adrenergic receptors. Identification and subcellular localization by (-)-[3H]dihydroalprenolol binding. 
  • Adolescent nicotine exposure produces immediate and long-term changes in CNS noradrenergic and dopaminergic function. 
  • Adolescents and adults differ in the immediate and long-term impact of nicotine administration and withdrawal on cardiac norepinephrine. 
  • Adrenergic dysregulation and pain with and without acute beta-blockade in women with fibromyalgia and temporomandibular disorder. 
  • Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth. 
  • Adrenomedullary function in the neonatal rat: responses to acute hypoxia. 
  • Aerobic exercise reduces levels of cardiovascular and sympathoadrenal responses to mental stress in subjects without prior evidence of myocardial ischemia. 
  • Affinity chromatography of adrenergic receptors and binding proteins. 
  • Age-dependence of inhibition of rat brain synaptic vesicle [3H]norepinephrine uptake caused by administration of a single dose of reserpine: persistence of inhibition in adults but not in neonates. 
  • Age-related changes in brain catecholamine responses to a single footshock. 
  • Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors. 
  • Alpha 1-adrenergic receptor mRNA level is regulated by norepinephrine in rabbit aortic smooth muscle cells. 
  • Alpha 1-adrenergic receptor-mediated downregulation of angiotensin II receptors in neuronal cultures. 
  • Alpha 1-adrenoceptor activity in arterial smooth muscle following congestive heart failure. 
  • Alpha-2 receptors mediate an endogenous noradrenergic suppression of kindling development. 
  • Alpha-adrenergic receptor subtypes. 
  • Alpha-adrenergic receptors in rat myocardium. Identification by binding of [3H]dihydroergocryptine. 
  • Alpha-receptor mediated inhibition of A2 noradrenergic neurons. 
  • Alterations in intrahepatic hemodynamics of the harvested porcine liver. 
  • An electrophysiological study of the forebrain projection of nucleus commissuralis: preliminary identification of presumed A2 catecholaminergic neurons. 
  • An in vitro neurite-promoting antigen functions in axonal regeneration in vivo. 
  • An interaction between tremorine and various autonomic agents on cardiac norepinephrine in the rat. 
  • Analysis of responses to serotonin in the pulmonary vascular bed of the cat. 
  • Angiotensin AT1 receptor inhibition. Effects on hypertrophic remodeling and ACE expression in rats with pressure-overload hypertrophy due to ascending aortic stenosis. 
  • Antiproliferative action of dopamine and norepinephrine in neuroblastoma cells expressing the human dopamine transporter. 
  • Aspartame and susceptibility to headache. 
  • Association between acute sympathetic response, early onset vasospasm, and delayed vasospasm following spontaneous subarachnoid hemorrhage. 
  • Association between sympathetic response, neurogenic cardiomyopathy, and venous thromboembolization in patients with primary subarachnoid hemorrhage. 
  • Association of depressive and anxiety symptoms with 24-hour urinary catecholamines in individuals with untreated high blood pressure. 
  • Association of electrocardiographic left ventricular hypertrophy with incident cardiovascular disease in Japanese older hypertensive patients. 
  • Atrial natriuretic factor: pharmacokinetics and cyclic GMP response in relation to biologic effects in severe heart failure. 
  • Augmentation of myocardial contractility by aorto-coronary bypass grafts in patients and experimental animals. Use of catecholamine infusion as a pharmacologic stress. 
  • Behavioral and prolactin responses to 5-hydroxytryptophan in rats treated during development with 5,7-dihydroxytryptamine. 
  • Behavioral responses to social stress in noradrenaline transporter knockout mice: effects on social behavior and depression. 
  • Beta adrenergic and muscarinic cholinergic receptors in canine myocardium. Effects of ischemia. 
  • Beta adrenergic control of macromolecule synthesis in neonatal rat heart, kidney and lung: relationship to sympathetic neuronal development. 
  • Beta adrenoceptor recovery after heart failure in the dog. 
  • Beta-adrenoreceptors determine affinity but not intrinsic activity of adenylate cyclase stimulants. 
  • Binding of catecholamines to receptors in cultured myocardial cells. 
  • Biological activity of agarose-immobilized catecholamines. 
  • Biological correlates of abuse in women with premenstrual dysphoric disorder and healthy controls. 
  • Blockade of thromboxane/endoperoxide receptor-mediated responses in the pulmonary vascular bed of the cat by sulotroban. 
  • Brain catecholamines and memory modulation: effects of footshock, amygdala implantation, and stimulation. 
  • CCK and other peptides modulate hypothalamic norepinephrine release in the rat: dependence on hunger or satiety. 
  • CSF catecholamine profile in subarachnoid hemorrhage patients with neurogenic cardiomyopathy. 
  • Caffeine affects cardiovascular and neuroendocrine activation at work and home. 
  • Caffeine effects on cardiovascular and neuroendocrine responses to acute psychosocial stress and their relationship to level of habitual caffeine consumption. 
  • Cardiac implications of increased arterial entry and reversible 24-h central and peripheral norepinephrine levels in melancholia. 
  • Cardiovascular and catecholamine responses to head-up tilt in the diagnosis of recurrent unexplained syncope in elderly patients. 
  • Catecholamine content of the carotid body in cats ventilated with 8 - 40% oxygen. 
  • Catecholamine-induced subsensitivity of adenylate cyclase associated with loss of beta-adrenergic receptor binding sites. 
  • Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice. 
  • Catecholaminergic regulation of opiate-stimulated growth hormone secretion in the developing rat. 
  • Catecholamines act via a beta-adrenergic receptor to maintain fetal heart rate and survival. 
  • Central catecholaminergic lesions in the developing rat: effects of cardiac noradrenaline levels, turnover and release. 
  • Central depression of carotid baroreceptor pressor response, arterial pressure and heart rate by 5-hydroxytryptophan: influence of supracollicular areas of the brain. 
  • Central sympathetic blockade ameliorates brain death-induced cardiotoxicity and associated changes in myocardial gene expression. 
  • Cerebral amino acid, norepinephrine and nitric oxide metabolism in CNS oxygen toxicity. 
  • Cerebral oxidative metabolism is decreased with extreme apnoea in humans; impact of hypercapnia. 
  • Changes in plasma noradrenaline and serotonin levels and craving during alcohol withdrawal. 
  • Characterization of the effect of cocaine on catecholamine uptake by pregnant myometrium. 
  • Chemically induced vasospasm: the effect of ischemia, vessel occlusion, and adrenergic blockade. 
  • Chlorpyrifos releases norepinephrine from adult and neonatal rat brain synaptosomes. 
  • Chronic ACE inhibition reduces intimal hyperplasia in experimental vein grafts. 
  • Chronic guanethidine treatment increases cardiac beta-adrenergic receptors. 
  • Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens. 
  • Circadian rhythms in rat mid-brain and caudate nucleus biogenic amine levels. 
  • Cocaine blocks extraneuronal uptake of norepinephrine by the pregnant human uterus. 
  • Cocaine inhibits central noradrenergic and dopaminergic activity during the critical developmental period in which catecholamines influence cell development. 
  • Cocaine-mediated impairment of cardiac conduction in the dog: a potential mechanism for sudden death after cocaine. 
  • Combinatorial pharmacogenetic interactions of bucindolol and β1, α2C adrenergic receptor polymorphisms. 
  • Combined catecholamine and indoleamine depletion following response to ECT. 
  • Commentary. Molecular pharmacology of beta-adrenergic receptors--a status report. 
  • Comparison of heart failure in children with enterovirus 71 rhombencephalitis and cats with norepinephrine cardiotoxicity. 
  • Compensatory response to hemorrhage in conscious dogs on normal and low salt intake. 
  • Complex neuronal systems: approach to development of new strategies in the treatment of epilepsy. 
  • Contribution of supracollicular structures of the brain to the central depression of cardiovascular function by clonidine. 
  • Contributions of neuroendocrine and local autocrine-paracrine mechanisms to the pathophysiology and pharmacology of congestive heart failure. 
  • Coronary collateral circulation during stress and the effects of aorta-coronary bypass grafts. 
  • Coupling of beta2-adrenoceptor to Gi proteins and its physiological relevance in murine cardiac myocytes. 
  • Critical role for the alpha-1B adrenergic receptor at the sympathetic neuroeffector junction. 
  • D-amphetamine challenge effects on Wisconsin Card Sort Test. Performance in schizotypal personality disorder. 
  • Decreased sensitivity to norepinephrine in vein bypass grafts. 
  • Decreased spontaneous motor activity parallels reserpine-induced supersensitivity of catecholamine-responsive rat cerebral cortex adenylate cyclase. 
  • Deficiency of dopamine-beta-hydroxylase. A new mechanism for normotensive pheochromocytomas. 
  • Delineation of discrete domains for substrate, cocaine, and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters. 
  • Dependence of serotonergic and other nonadrenergic enteric neurons on norepinephrine transporter expression. 
  • Depletion of brain amines reverses blood pressure response to footshock in rat. 
  • Depression and anxiety symptoms are related to increased 24-hour urinary norepinephrine excretion among healthy middle-aged women. 
  • Depression and enhancement of baroreceptor pressor response in cats after intracerebroventricular injection of noradrenergic blocking agents: dependence on supracollicular areas of the brain. 
  • Desvenlafaxine, a serotonin-norepinephrine uptake inhibitor for major depressive disorder, neuropathic pain and the vasomotor symptoms associated with menopause. 
  • Detecting pheochromocytoma: defining the most sensitive test. 
  • Determinants of central sympathetic activation in spontaneous primary subarachnoid hemorrhage. 
  • Development of alpha-noradrenergic and Dopaminergic receptor systems depends on maturation of their presynaptic nerve terminals in the rat brain. 
  • Development of central control of norepinephrine turnover and release in the rat heart: responses to tyramine, 2-deoxyglucose and hydralazine. 
  • Development of new pharmacological agents for epilepsy: lessons from the kindling model. 
  • Developmental effects of alpha-fluoromethylhistidine, an irreversible inhibitor of histidine decarboxylase, on growth and on levels and turnover of catecholamines. 
  • Developmental neurotoxicity targeting hepatic and cardiac sympathetic innervation: effects of organophosphates are distinct from those of glucocorticoids. 
  • Developmental shift from local to central control of norepinephrine release in the cardiac-sympathetic axis: effects of cocaine and related drugs. 
  • Diazinon and parathion diverge in their effects on development of noradrenergic systems. 
  • Differences in peripheral noradrenergic function among actively drinking and abstinent alcohol-dependent individuals. 
  • Differential desensitization and phosphorylation of three cloned and transfected alpha 2-adrenergic receptor subtypes. 
  • Differential regulation of receptor-stimulated cyclic adenosine monophosphate production by polyvalent cations in MC3T3-E1 osteoblasts. 
  • Differentiation of hemodynamic, humoral and metabolic responses to beta 1- and beta 2-adrenergic stimulation in man using atenolol and propranolol. 
  • Direct demonstration of impaired functionality of a purified desensitized beta-adrenergic receptor in a reconstituted system. 
  • Direct identification and characterisation of beta-adrenergic receptors in rat brain. 
  • Direct studies of beta-adrenergic receptors intact frog erythrocytes. 
  • Disruption of rat forebrain development by glucocorticoids: critical perinatal periods for effects on neural cell acquisition and on cell signaling cascades mediating noradrenergic and cholinergic neurotransmitter/neurotrophic responses. 
  • Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system. 
  • Do sympathetic neurons coordinate cellular development in the heart and kidney? Effects of neonatal central and peripheral catecholaminergic lesions on cardiac and renal nucleic acids and proteins. 
  • Does growth impairment underlie the adverse effects of dexamethasone on development of noradrenergic systems? 
  • Dopamine turnover in the mediobasal hypothalamus in rat fetuses. 
  • Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. 
  • Dose-dependent glucocorticoid effects on noradrenergic synaptogenesis in rat brain: ontogeny of [3H]desmethylimipramine binding sites after fetal exposure to dexamethasone. 
  • Dual natriuretic peptide system in experimental heart failure. 
  • Effect of acute exercise on plasma neurotensin levels. 
  • Effect of blood pressure on A2 noradrenergic neurons. 
  • Effect of brief myocardial ischemia on sympathetic coronary vasoconstriction. 
  • Effect of cocaine on intracellular calcium regulation in myometrium from pregnant women. 
  • Effect of denervation on endothelium-derived relaxing factor-dependent relaxation in the rat cremaster muscle. 
  • Effect of exogenous catecholamines in the amygdala of a 'rage' cat. 
  • Effect of intracerebral norepinephrine depletion on outcome from severe forebrain ischemia in the rat. 
  • Effect of isradipine on cardiopulmonary baroreflex function, regional blood flow, and vascular responsiveness in hypertensive patients. 
  • Effect of norepinephrine, epinephrine, and angiotensin on blood flow in the internal carotid artery of man. 
  • Effect of pharmacologic increases in afterload on left ventricular rotation and strain in a rabbit model. 
  • Effect of the monoamine oxidase inhibitors clorgyline and pargyline on the hyperphagia of obese mice. 
  • Effect of the selective noradrenergic reuptake inhibitor reboxetine on the firing activity of noradrenaline and serotonin neurons. 
  • Effects of acute tryptophan depletion on brain serotonin function and concentrations of dopamine and norepinephrine in C57BL/6J and BALB/cJ mice. 
  • Effects of alpha-fluoromethylhistidine (FMH), an irreversible inhibitor of histidine decarboxylase, on development of brain histamine and catecholamine systems in the neonatal rat. 
  • Effects of amphetamines and small related molecules on recovery after stroke in animals and man. 
  • Effects of chronic antidepressant drug administration and electroconvulsive shock on locus coeruleus electrophysiologic activity. 
  • Effects of dorsal noradrenergic bundle lesions on recovery after sensorimotor cortex injury. 
  • Effects of neurochemicals upon a dinoflagellate photoresponse. 
  • Effects of neurotoxic destruction of descending noradrenergic pathways on cannabinoid antinociception in models of acute and tonic nociception. 
  • Effects of perinatal exposure to methadone on development of neurotransmission: biochemical bases for behavioral alterations. 
  • Effects of prenatal nicotine exposure on neuronal development: selective actions on central and peripheral catecholaminergic pathways. 
  • Effects of propranolol on cardiovascular and neuroendocrine responses to mental arithmetic in type A men. 
  • Effects of relaxation therapy on patients with type I diabetes mellitus. 
  • Effects of serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibition plus 5-HT(2A) receptor antagonism on the firing activity of norepinephrine neurons. 
  • Effects of sustained gamma-hydroxybutyrate treatments on spontaneous and evoked firing activity of locus coeruleus norepinephrine neurons. 
  • Effects of the selective norepinephrine reuptake inhibitor reboxetine on norepinephrine and serotonin transmission in the rat hippocampus. 
  • Effects of vasomotor- and mediator-induced hypotension on bronchomotor tone in swine. 
  • Endothelium-dependent relaxations in canine coronary arteries are enhanced in early heart failure and persist in recovery. 
  • Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine. 
  • Evaluation of selective liver denervation methods. 
  • Exposure to methylmercury in utero: effects on biochemical development of catecholamine neurotransmitter systems. 
  • Expression of functional estrogen receptor beta in locus coeruleus-derived Cath.a cells. 
  • Extrarenal contributions to indapamide's antihypertensive mechanism of action. 
  • Fetal cocaine exposure causes persistent noradrenergic hyperactivity in rat brain regions: effects on neurotransmitter turnover and receptors. 
  • Fetal dexamethasone exposure interferes with establishment of cardiac noradrenergic innervation and sympathetic activity. 
  • Fetal nicotine exposure ablates the ability of postnatal nicotine challenge to release norepinephrine from rat brain regions. 
  • Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. 
  • Flow stimulates endothelial cells to release a nitrovasodilator that is potentiated by reduced thiol. 
  • Functional and pharmacological characterization of the modulatory role of serotonin on the firing activity of locus coeruleus norepinephrine neurons. 
  • Functional development of the cervical sympathetic pathway in the neonatal rat. 
  • Functional reconstitution of the alpha 2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles. 
  • G protein-coupled receptor kinase 5 in cultured vascular smooth muscle cells and rat aorta. Regulation by angiotensin II and hypertension. 
  • G protein-coupled receptor kinase mediates desensitization of norepinephrine-induced Ca2+ channel inhibition. 
  • Gamma-butyrolactone sleep: A 24-hour rhythm paralleling normal sleep in the rat and CNS amine changes. 
  • Genetic approaches to studying norepinephrine function: knockout of the mouse norepinephrine transporter gene. 
  • Glipizide stimulates sympathetic outflow in diabetes-prone mice. 
  • Glucocorticoids and the development of neuronal function: effects of prenatal dexamethasone exposure on central noradrenergic activity. 
  • Heart rate and metabolic response to competitive squash in veteran players: identification of risk factors for sudden cardiac death. 
  • Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats : possible role in renoprotection. 
  • Hemodynamic and metabolic responses to exercise after adrenoceptor blockade in humans. 
  • Hepatic fibrogenesis requires sympathetic neurotransmitters. 
  • Heroin neuroteratogenicity: delayed-onset deficits in catecholaminergic synaptic activity. 
  • High oxygen prevents fetal lethality due to lack of catecholamines. 
  • Histamine-, norepinephrine-, and dopamine-sensitive central adenylate cyclases: effects of chlorpromazine derivatives and butaclamol. 
  • Homeostatic regulation of airway smooth muscle tone by catecholamine secretion in swine. 
  • Hormone receptor complexes and their modulation of membrane function. 
  • Hormone replacement improves hemodynamic profile and left ventricular geometry in hypertensive and normotensive postmenopausal women. 
  • Hostility is related to blunted beta-adrenergic receptor responsiveness among middle-aged women. 
  • Human saphenous vein grafts explanted from the arterial circulation demonstrate altered smooth-muscle and endothelial responses. 
  • Hypercholesterolemia and experimental vein grafts: accelerated development of intimal hyperplasia and an increase in abnormal vasomotor function. 
  • Hypertension and cardiovascular hypertrophy during chronic catecholamine infusion in rats. 
  • Hypertension associated with alcohol withdrawal: assessment of mechanisms and complications. 
  • Hyponatremia in congestive heart failure: implications for neurohumoral activation and responses to orthostasis. 
  • Hypotensive effect of intracerebroventricular injection of norepinephrine and its modulation by alpha and beta adrenergic blockers in conscious rabbits. 
  • Hypothermia: role of alpha 1- and alpha 2-noradrenergic receptors in the hypothalamus of the cat. 
  • Idazoxan blocks the nicotine-induced reversal of the memory impairment caused by the NMDA glutamate receptor antagonist dizocilpine. 
  • Identification of adenylate cyclase-coupled beta-adrenergic receptors in frog erythrocytes with (minus)-[3-H] alprenolol. 
  • Identification of beta-adrenergic receptors in human lymphocytes by (-) (3H) alprenolol binding. 
  • Identification of cardiac beta-adrenergic receptors by (minus) [3H]alprenolol binding. 
  • Identification of the cardiac beta-adrenergic receptor protein: solubilization and purification by affinity chromatography. 
  • Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction. 
  • Impaired development of central and peripheral catecholamine neurotransmitter systems in preweanling rats treated with alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase. 
  • Impaired thermoregulation and beneficial effects of thermoneutrality in the 3×Tg-AD model of Alzheimer's disease. 
  • Important role of endogenous norepinephrine and epinephrine in the development of in vivo pressure-overload cardiac hypertrophy. 
  • In search of a mechanism for receptor-mediated neurobehavioral teratogenesis by nicotine: catecholamine release by nicotine in immature rat brain regions. 
  • In vivo modulation of norepinephrine-induced cerebral oxygenation states by hypoxia and hyperoxia. 
  • Increased vascular contraction and sensitivity to norepinephrine after endothelial denudation is inhibited by prazosin. 
  • Influence of E. coli endotoxin on serotonin contractions of the rabbit aortic strip. 
  • Influence of prostaglandin E1 on the terminal vascular bed. 
  • Inhibition of GH in maternal separation may be mediated through altered serotonergic activity at 5-HT2A and 5-HT2C receptors. 
  • Inhibition of spontaneous beta 2-adrenergic activation rescues beta 1-adrenergic contractile response in cardiomyocytes overexpressing beta 2-adrenoceptor. 
  • Inhibitory effects of DuP 753 and EXP3174 on responses to angiotensin II in pulmonary vascular bed of the cat. 
  • Inhibitory role of the coronary arterial endothelium to alpha-adrenergic stimulation in experimental heart failure. 
  • Interactions of agonists with platelet alpha 2-adrenergic receptors. 
  • Intravenous nisoldipine in severe congestive heart failure. 
  • Iodine 131-labeled metaiodobenzylguanidine scintigraphy and biochemical analyses in suspected pheochromocytoma. 
  • Ionic and nucleotide cofactor requirements for uptake of [3H]norepinephrine by rat brain synaptic vesicle preparations. 
  • Iron deficiency anemia and increased urinary norepinephrine excretion. 
  • Isolated beta-adrenergic binding sites: a potential assay vehicle for catecholamines. 
  • Left ventricular myocardial blood flow, metabolism, and effects of treatment with enalapril: further insights into the mechanisms of canine experimental pacing-induced heart failure. 
  • Location of CNS neurons mediating the blood pressure fall after shock-induced fighting in the rat. 
  • Loss of neonatal hypoxia tolerance after prenatal nicotine exposure: implications for sudden infant death syndrome. 
  • Magnesium-calcium antagonism in the contraction of arterioles. 
  • Maternal methadone administration: deficit in development of alpha-noradrenergic responses in developing rat brain as assessed by norepinephrine stimulation of 33Pi incorporation into phospholipids in vivo. 
  • Maternal psychological distress, prenatal cortisol, and fetal weight. 
  • Maturation of sympathetic neurotransmission in the rat heart--III. Developmental changes in reserpine inhibition of norepinephrine uptake into isolated synaptic vesicles. 
  • Maturation of sympathetic neurotransmission in the rat heart. I. Ontogeny of the synaptic vesicle uptake mechanism and correlation with development of synaptic function. Effects of neonatal methadone administration on development of synaptic vesicles. 
  • Maturation of sympathetic neurotransmission in the rat heart. II. Enhanced development of presynaptic and postsynaptic components of noradrenergic synapses as a result of neonatal hyperthyroidism. 
  • Maturation of sympathetic neurotransmission in the rat heart. IX. Development of transsynaptic regulation of cardiac adrenergic sensitivity. 
  • Maturation of sympathetic neurotransmission in the rat heart. VIII. Slowed development of noradrenergic synapses resulting from hypothyroidism. 
  • Mechanisms of airway hypercontractility in basenji-greyhound dogs. 
  • Methadone inhibits serotonin and norephinephrine uptake into rat brain synaptosomes and synaptic vesicles in vitro but not in vivo. 
  • Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. 
  • Mimicking maternal smoking and pharmacotherapy of preterm labor: fetal nicotine exposure enhances the effect of late gestational dexamethasone treatment on noradrenergic circuits. 
  • Monoamine oxidase and catechol-O-methyltransferase activity in hamster and rat insulinomas. 
  • Monoamine precursors in the treatment of depression. 
  • Monoamine transporter gene polymorphisms and antidepressant response in koreans with late-life depression. 
  • Morning blood pressure surge, morning platelet aggregation, and silent cerebral infarction in older Japanese hypertensive patients. 
  • Negative cooperativity among beta-adrenergic receptors in frog erythrocyte membranes. 
  • Neonatal 6-hydroxydopamine lesions of the frontal cortex in rats: persisting effects on locomotor activity, learning and nicotine self-administration. 
  • Neonatal central catecholaminergic lesions with intracisternal 6-hydroxydopamine: effects on development of presynaptic and postsynaptic components of peripheral sympathetic pathways and on the ornithine decarboxylase/polyamine system in heart, lung and kidney. 
  • Neonatal chlorpyrifos exposure alters synaptic development and neuronal activity in cholinergic and catecholaminergic pathways. 
  • Neonatal hyperthyroidism causes premature development of baroreceptor-mediated cardiac sympathetic reflexes. 
  • Neonatal methylmercury poisoning in the rat: effects on development of central catecholamine neurotransmitter systems. 
  • Neonatal rat pinealocytes: typical and atypical characteristics of [125I]iodohydroxybenzylpindolol binding and adenosine 3',5'-monophosphate accumulation. 
  • Neural input and the development of adrenergic intracellular signaling: neonatal denervation evokes neither receptor upregulation nor persistent supersensitivity of adenylate cyclase. 
  • Neurobiological mechanisms in generalized anxiety disorder. 
  • Neuroendocrine response to cold in Raynaud's syndrome. 
  • Neuroendocrine responses to caffeine in the work environment. 
  • Neuroendocrine, cardiovascular, and emotional responses of hostile men: the role of interpersonal challenge. 
  • Neuronal control of cardiac and hepatic macromolecule synthesis in the neonatal rat: effects of sympathectomy. 
  • Neuronal localization of the enhanced adenylate cyclase responsiveness to catecholamines in the rat cerebral cortex following reserpine injections. 
  • Neuropharmacology of TBI-induced plasticity. 
  • Neuropsychological correlates of central monoamine function in chronic schizophrenia: relationship between CSF metabolites and cognitive function. 
  • Neurotransmitters and motor activity: effects on functional recovery after brain injury. 
  • New double-lumen polyethylene cannula for push-pull perfusion of brain tissue in vivo. 
  • Non-neurogenic stimulation of adrenomedullary secretion during endotoxicosis in the one day old rat. 
  • Noradrenaline biosynthesis and metabolism during development and recovery from pacing-induced heart failure in the dog. 
  • Noradrenaline treatment of rats stimulates H2O2 generation in liver mitochondria. 
  • Noradrenaline-functionalized hyperbranched fluoropolymer-poly(ethylene glycol) cross-linked networks as dual-mode, anti-biofouling coatings. 
  • Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony. 
  • Noradrenergic induction of odor-specific neural habituation and olfactory memories. 
  • Norepinephrine and neuropeptide Y promote proliferation and collagen gene expression of hepatic myofibroblastic stellate cells. 
  • Norepinephrine content of the rat kidney during development: alterations induced by perinatal methadone. 
  • Norepinephrine induces hepatic fibrogenesis in leptin deficient ob/ob mice. 
  • Norepinephrine regulates hepatic innate immune system in leptin-deficient mice with nonalcoholic steatohepatitis. 
  • Norepinephrine transport-mediated gene expression in noradrenergic neurogenesis. 
  • Norepinephrine transporter-deficient mice exhibit excessive tachycardia and elevated blood pressure with wakefulness and activity. 
  • Norepinephrine-induced down regulation of alpha 1 adrenergic receptors in cultured rabbit aorta smooth muscle cells. 
  • Norepinephrine: dissociation of -receptor binding from adenylate cyclase activation in solubilized myocardium. 
  • Normal endothelial function and decreased vasoreactivity of experimental arterial grafts. 
  • Obligatory role of thyroid hormones in development of peripheral sympathetic and central nervous system catecholaminergic neurons: effects of propylthiouracil-induced hypothyroidism on transmitter levels, turnover and release. 
  • Ontogeny of (--)-[3H]norepinephrine uptake properties of synaptic storage vesicles of rat brain. 
  • Paradoxical elevation of sympathetic activity during catecholamine infusion in rats. 
  • Perinatal dietary supplementation with a soy lecithin preparation: effects on development of central catecholaminergic neurotransmitter systems. 
  • Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain. 
  • Pharmacokinetics, hemodynamic, renal, and neurohormonal effects of atrial natriuretic factor in experimental heart failure. 
  • Pharmacological approach to functional reorganization: the role of norepinephrine. 
  • Phorbol ester effects on alpha 1-adrenoceptor binding and phosphatidylinositol metabolism in cultured vascular smooth muscle cells. 
  • Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism. 
  • Physiological effects of synthetic atrial natriuretic factor in normal conscious dogs. 
  • Physiological responses to catecholamine infusions in type A and type B men. 
  • Plasma membrane transporters of serotonin, dopamine, and norepinephrine mediate serotonin accumulation in atypical locations in the developing brain of monoamine oxidase A knock-outs. 
  • Platelet alpha 2-adrenergic receptors in schizophrenic patients before and after phenothiazine treatment. 
  • Positive affect is associated with cardiovascular reactivity, norepinephrine level, and morning rise in salivary cortisol. 
  • Potential mechanisms of action of atypical antipsychotic medications in treatment-resistant depression and anxiety. 
  • Potentiated opioid analgesia in norepinephrine transporter knock-out mice. 
  • Pre-ischemic depletion of brain norepinephrine decreases infarct size in normothermic rats exposed to transient focal cerebral ischemia. 
  • Predictors of 30-day mortality in patients with refractory cardiogenic shock following acute myocardial infarction despite a patent infarct artery. 
  • Pregnancy anxiety and comorbid depression and anger: effects on the fetus and neonate. 
  • Pregnant women benefit from massage therapy. 
  • Prenatal drug exposures sensitize noradrenergic circuits to subsequent disruption by chlorpyrifos. 
  • Prenatal dysthymia versus major depression effects on maternal cortisol and fetal growth. 
  • Prenatal exposure to nicotine impairs nervous system development at a dose which does not affect viability or growth. 
  • Prenatal terbutaline exposure in the rat: selective effects on development of noradrenergic projections to cerebellum. 
  • Pressor mechanisms linked obligatorily to spontaneous hypertension in the rat. 
  • Presynaptic input regulates development of beta-adrenergic control of rat brain ornithine decarboxylase: effects of 6-hydroxydopamine or propranolol. 
  • Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: relation to hypercortisolism and corticotropin-releasing hormone. 
  • Protein kinase A, cytosolic calcium, and phosphate uptake in human proximal renal cells. 
  • Race and sex differences in cardiovascular α-adrenergic and β-adrenergic receptor responsiveness in men and women with high blood pressure. 
  • Radioenzymatic assay of platelet serotonin, dopamine and norepinephrine in subjects with normal and increased serotonin production. 
  • Rapid ventricular pacing in the dog: pathophysiologic studies of heart failure. 
  • Rapid ventricular pacing of dogs to heart failure: biochemical and physiological studies. 
  • Rat brain amines, blood histamine and glucose levels in relationship to circadian changes in sleep induced by pentobarbitone sodium. 
  • Rat brain synaptic vesicles: uptake specificities of [3H]norepinephrine and [3H]serotonin in preparations from whole brain and brain regions. 
  • Rat fighting behavior: serum dopamine- -hydroxylase and hypothalamic tyrosine hydroxylase. 
  • Receptor class desensitization of leukocyte chemoattractant receptors. 
  • Recovery of attenuated baroreflex sensitivity in conscious dogs after reversal of pacing induced heart failure. 
  • Reduction of experimental vein graft intimal hyperplasia by ketanserin. 
  • Regional brain catecholamines and memory: effects of footshock, amygdala implantation, and stimulation. 
  • Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function. 
  • Regulation and localization of HSP70 and HSP25 in the kidney of rats undergoing long-term administration of angiotensin II. 
  • Regulation of adenylate cyclase coupled beta-adrenergic receptors by beta-adrenergic catecholamines. 
  • Regulation of adenylate cyclase coupled beta-adrenergic receptors. 
  • Regulation of adenylate cyclase-coupled beta adrenergic receptor binding sites by beta adrenergic catecholamines in vitro. 
  • Regulation of adrenal chromaffin cell development by the central monoaminergic system: differential control of norepinephrine and epinephrine levels and secretory responses. 
  • Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells. 
  • Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase. 
  • Regulation of hippocampal sympathetic ingrowth: role of afferent input. 
  • Regulation of the uncoupling protein gene (Ucp) by beta 1, beta 2, and beta 3-adrenergic receptor subtypes in immortalized brown adipose cell lines. 
  • Relation between functional maturation of cervical sympathetic innervation and ontogeny of alpha-noradrenergic smooth muscle contraction in the rat. 
  • Release of [3H]norepinephrine from synaptic vesicles isolated from rat brain after the intracisternal administration of [3H]norepinephrine: influence of nucleotides, ions and drugs, and destabilization of transmitter storage caused by acute or chronic lithium administration. 
  • Responsiveness of atrial natriuretic factor to reduction in right atrial pressure in patients with chronic congestive heart failure. 
  • Responsiveness of vein bypass grafts to stimulation with norepinephrine and 5-hydroxytryptamine. 
  • Right vs. left sensorimotor cortex suction-ablation in the rat: no difference in beam-walking recovery. 
  • Role of carotid body catecholamines in chemoreceptor function. 
  • Role of leptin in fat regulation. 
  • Role of neurotransmitters in seizure mechanisms in the kindling model of epilepsy. 
  • Role of noradrenergic hyperactivity in neonatal opiate abstinence. 
  • Role of stress in the etiology and treatment of diabetes mellitus. 
  • Role of sympathetic neurons in development of beta-adrenergic control of ornithine decarboxylase activity in peripheral tissues: effects of neonatal 6-hydroxydopamine treatment. 
  • Role of α2-agonists in the treatment of acute alcohol withdrawal. 
  • Rostral hypothalamus: a new neuroanatomical site of neurochemically-induced emesis in the cat. 
  • Saphenous vein endothelium-dependent relaxation in patients with peripheral vascular disease. 
  • Selective autoregulation of endothelins in primary astrocyte cultures: endothelin receptor-mediated potentiation of endothelin-1 secretion. 
  • Selective supersensitivity to norepinephrine in intimal thickened rabbit aorta. 
  • Serotonin (1A) receptor ligands act on norepinephrine neuron firing through excitatory amino acid and GABA(A) receptors: a microiontophoretic study in the rat locus coeruleus. 
  • Serum lipids, neuroendocrine and cardiovascular responses to stress in healthy Type A men. 
  • Serum lipids, neuroendocrine, and cardiovascular responses to stress in men and women with mild hypertension. 
  • Severe hypotension is not essential for isoflurane neuroprotection against forebrain ischemia in mice. 
  • Sleep disturbances in depressed pregnant women and their newborns. 
  • Solubilization and characterization of the beta-adrenergic receptor binding sites of frog erythrocytes. 
  • Specific binding of -adrenergic catecholamines to a subcellular fraction from cardiac muscle. 
  • Specific inhibitors implicate a soluble metalloendoproteinase in exocytosis. 
  • Sprouting of noradrenergic fibers in hippocampus after medial septal lesions: contributions of the central and peripheral nervous systems. 
  • Stereospecific (3H)(minus)-alprenolol binding sites, beta-adrenergic receptors and adenylate cyclase. 
  • Stimulation of ornithine decarboxylase by histamine or norepinephrine in brain regions of the developing rat: evidence for biogenic amines as trophic agents in neonatal brain development. 
  • Stress in employed women: impact of marital status and children at home on neurohormone output and home strain. 
  • Stress in the fetus and newborn. 
  • Stress-induced changes in the expression of monocytic beta2-integrins: the impact of arousal of negative affect and adrenergic responses to the Anger Recall Interview. 
  • Structural characteristics for inhibition of [3H] norepinephrine uptake into rat brain synaptic vesicles by beta-carboline, indolealkylamine, phenethylamine and n-alkylamine derivatives. 
  • Structural remodelling in heart failure: gelatinase induction. 
  • Studies of blood flow in aorta-to-coronary venous bypass grafts in man. 
  • Studies on behavior. V. Actions of l-epinephrine and related compounds. 
  • Surrogate end points in heart failure trials. 
  • Sustained Adrenergic Signaling Promotes Intratumoral Innervation through BDNF Induction. 
  • Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis. 
  • Sympathetic nervous system regulation of liver repair. 
  • Sympathoadrenergic mechanisms in reduced hemodynamic stress responses after exercise. 
  • Synaptic development in brains of rats exposed perinatally to ethanol. 
  • Synaptic vesicles isolated from rat heart: l-[3H]norepinephrine uptake properties. 
  • Synergistic effect of chronic kidney disease and high circulatory norepinephrine level on stroke risk in Japanese hypertensive patients. 
  • Systemic hypertension alters vasomotor function in experimental vein grafts. 
  • TREMORINE: ITS EFFECT ON AMINES OF THE CENTRAL NERVOUS SYSTEM. 
  • Tactile-kinesthetic stimulation effects on sympathetic and adrenocortical function in preterm infants. 
  • Temperature immutability of adenyl cyclase-coupled beta adrenergic receptors. 
  • Temporal alterations in peripheral vascular responsiveness during both the development and recovery from pacing-induced heart failure. 
  • The alpha 1C-adrenergic receptor: characterization of signal transduction pathways and mammalian tissue heterogeneity. 
  • The beta-adrenergic receptor in heart failure. 
  • The concentration of catecholamines in the turtle heart and vagal escape. 
  • The dissociation of catecholamine and hypothalamic-pituitary-adrenal responses to daily stressors using dexamethasone. 
  • The effect of hypoxia on baroreflexes and pressor sensitivity in sleep apnea and hypertension. 
  • The in vitro effects of phosphodiesterase inhibitors on the human internal mammary artery. 
  • The influence of drug ,reatment on norepinephrine levels and ultrastructure of the rat hypothalamus and caudate nucleus during a programmed light-dark cycle. 
  • The noradrenergic system in cultured aggregates of fetal rat brain cells: morphology of the aggregates and pharmacological indices of noradrenergic neurons. 
  • The relaxant effect of diazoxide on isolated gravid and nongravid human myometrium. 
  • The selective serotonin reuptake inhibitor citalopram induces the storage of serotonin in catecholaminergic terminals. 
  • The third beta is not the charm. 
  • Theoretical and empirical issues in the treatment of post-traumatic stress disorder in Vietnam veterans. 
  • Therapy of malignant hamster insulinomas with monoamine precursors. 
  • Tissue norepinephrine concentration in spontaneously diabetic Chinese hamsters. 
  • Toxic effects of catecholamines on skin. 
  • Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells. 
  • Transgenic manipulation of beta-adrenergic receptor kinase modifies cardiac myocyte contraction to norepinephrine. 
  • Transient postnatal elevation of norepinephrine content and turnover in brain regions of rats exposed to terbutaline prenatally: evidence for autoregulation of noradrenergic development? 
  • Translocation and uncoupling of the beta-adrenergic receptor in rat lung after catecholamine promoted desensitization in vivo. 
  • Treating shock--old drugs, new ideas. 
  • Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor. 
  • Undernutrition and overnutrition in the neonatal rat: long-term effects on noradrenergic pathways in brain regions. 
  • Unified thalamic model generates multiple distinct oscillations with state-dependent entrainment by stimulation. 
  • Uptake and release of norepinephrine by serotonergic terminals in norepinephrine transporter knock-out mice: implications for the action of selective serotonin reuptake inhibitors. 
  • Uptake of (-) 3H-norepinephrine by storage vesicles prepared from whole rat brain: properties of the uptake system and its inhibition by drugs. 
  • Uptake, storage, and distribution of amines in bovine adrenal medullary vesicles. 
  • Urinary catecholamine excretion in childhood overanxious and posttraumatic stress disorders. 
  • Vascular smooth muscle responsiveness to noradrenaline and phenylephrine following experimental heart failure in dogs. 
  • Vasoactive drugs produce selective changes in flow to experimental brain tumors. 
  • Vasodilator action of pentoxifylline on microcirculation of rat cremaster muscle. 
  • Vasoinhibitory action of proteolytic enzyme inhibitors in the capillary bed. 
  • Verapamil prolongs atrial fibrillation by evoking an intense sympathetic neurohumoral effect. 
  • [3H]dihydroergocryptine binding in rat brain. 
  • alpha-Adrenergic receptors in rat parotid cells. I. Correlation of [3H]dihydroergocryptine binding and catecholamine-stimulated potassium efflux. 
  • beta-Adrenergic receptor regulation by agonists and membrane depolarization in rat brain slices. 
  • pH dependence of [3H]norepinephrine uptake into catecholamine storage vesicles isolated from rat brain, heart and adrenal medulla. 
• 

  Keywords of People

  • McDonnell, Donald Patrick, Chair, Department of Pharmacology & Cancer Biology, Duke Innovation & Entrepreneurship
  • Middleton, John Paul, Associate Professor of Medicine, Medicine, Nephrology
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. / Guidant Foundation Distinguished Professor of Cardiology, Medicine, Clinical Pharmacology
  • Warner, David Samuel, Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology