Magnetic Resonance Spectroscopy

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  Subject Areas on Research

  • 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS). 
  • 1990 ARRS Executive Council Award. Renal transplant rejection: diagnosis with 31P MR spectroscopy. 
  • 1H MRSI comparison of white matter and lesions in primary progressive and relapsing-remitting MS. 
  • 1H NMR spectroscopy of DNA. 
  • 2'-O-Methylation can increase the abundance and lifetime of alternative RNA conformational states. 
  • 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. 
  • 31P-NMR of free and protein-bound molybdopterin guanine dinucleotide. 
  • 57Fe and 1H electron-nuclear double resonance of three doubly reduced states Escherichia coli sulfite reductase. 
  • A Bayesian approach for determining protein side-chain rotamer conformations using unassigned NOE data. 
  • A DNA mimic: the structure and mechanism of action for the anti-repressor protein AbbA. 
  • A Hausdorff-based NOE assignment algorithm using protein backbone determined from residual dipolar couplings and rotamer patterns. 
  • A Scalable Synthesis of the Difluoromethyl-allo-threonyl Hydroxamate-Based LpxC Inhibitor LPC-058. 
  • A facile synthesis of 1-O-alkyl-2-(R)-hydroxypropane-3-phosphonocholine (lyso-phosphono-platelet activating factor). 
  • A geometric arrangement algorithm for structure determination of symmetric protein homo-oligomers from NOEs and RDCs. 
  • A high-temperature superconducting receiver for nuclear magnetic resonance microscopy. 
  • A magnetic resonance spectroscopic imaging study of adult nonhuman primates exposed to early-life stressors. 
  • A neuroradiology self-assessment module for use in emergency radiology. 
  • A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures. 
  • A novel inflammatory biomarker, GlycA, associates with disease activity in rheumatoid arthritis and cardio-metabolic risk in BMI-matched controls. 
  • A nuclear magnetic resonance study of the interaction of L-epinephrine with phospholipid vesicles. 
  • A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases. 
  • A probe for specimen magnetic resonance microscopy. 
  • A protocol for quantifying cardiogenic oscillations in dynamic 129 Xe gas exchange spectroscopy: The effects of idiopathic pulmonary fibrosis. 
  • A proton and phosphorus nuclear magnetic resonance study of ternary complexes of cyclic adenosine 3':5'-monophosphate, adenosine 5'-triphosphate, and Mn2+. 
  • A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion. 
  • A rare example of lock-and-key RNA recognition. 
  • A refocused and optimized HNCA: increased sensitivity and resolution in large macromolecules. 
  • A repeat proton magnetic resonance spectroscopy study in social phobia. 
  • A review of 1H MR spectroscopy findings in Alzheimer's disease. 
  • A simple method for processing NMR spectra in which acquisition is delayed: applications to in vivo localized 31P NMR spectra acquired using the DRESS technique. 
  • A simplified sequence for observing deoxymyoglobin signals in vivo: myoglobin excitation with dynamic unexcitation and saturation of water and fat (MEDUSA). 
  • A slow, tight-binding inhibitor of the zinc-dependent deacetylase LpxC of lipid A biosynthesis with antibiotic activity comparable to ciprofloxacin. 
  • Abnormal parathyroid glands: high-resolution MR imaging. 
  • Accessing long-lived disconnected spin-1/2 eigenstates through spins > 1/2. 
  • Acute changes in serum lipids and lipoprotein subclasses in triathletes as assessed by proton nuclear magnetic resonance spectroscopy. 
  • Acute renal allograft rejection: difficulty in diagnosis of histologically mild cases by MR imaging. 
  • Acute stroke: evaluation with serial proton MR spectroscopic imaging. 
  • Additional Magnetic Resonance or Nuclear Scintigraphy Imaging Influences Approach to Vertebral Augmentation: A Single Institution Experience. 
  • Adnexal masses: MR imaging observations at 1.5 T, with US and CT correlation. 
  • Advanced magnetic resonance spectroscopic neuroimaging: Experts' consensus recommendations. 
  • Advances, interactions, and future developments in the CNS, Phenix, and Rosetta structural biology software systems. 
  • Alterations in bone marrow metabolism are an early and consistent feature during the development of MGUS and multiple myeloma. 
  • Alterations in inorganic phosphate in mouse hindlimb muscles during limb disuse. 
  • Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study. 
  • Altered development of the dorsolateral prefrontal cortex in chromosome 22q11.2 deletion syndrome: an in vivo proton spectroscopy study. 
  • Altered phosphate metabolism in myocardial infarction: P-31 MR spectroscopy. 
  • Amiodarone-liposome interaction: a multinuclear NMR and X-ray diffraction study. 
  • An NMR study of the rates of single-molecule exchange in a cylindrical host capsule. 
  • An increase in the myocardial PCr/ATP ratio in GLUT4 null mice. 
  • An unusual dienone-phenol rearrangement product formed during the synthesis of mometasone furoate (Sch 32088). 
  • An unusual rearrangement product formed during production of mometasone furoate (Sch 32088). 
  • Analysis of the binding specificities of oligomannoside-binding proteins using methylated monosaccharides. 
  • Anion binding of short, flexible aryl triazole oligomers. 
  • Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches. 
  • Anti-AIDS agents--XXVII. Synthesis and anti-HIV activity of betulinic acid and dihydrobetulinic acid derivatives. 
  • Antigens from synthetic and natural estrogens: formation by conjugation with protein through a thiopropionic acid link. 
  • Antitumor Agents, CLI. Bis(helenalinyl)Glutarate and Bis(isoalantodiol-B)-Glutarate, Potent Inhibitors of Human DNA Topoisomerase II 
  • Antitumor Agents. 152. In Vitro Inhibitory Activity of Etoposide Derivative NPF Against Human Tumor Cell Lines and a Study of its Conformation by X-Ray Crystallography, Molecular Modeling, and NMR Spectroscopy 
  • Antitumor Agents. 154. Cytotoxic and Antimitotic Flavonols from Polanisia dodecandra 
  • Antitumor agents, 135. Structure and stereochemistry of polacandrin, a new cytotoxic triterpene from Polanisia dodecandra. 
  • Antitumor agents, 79. Cytotoxic antileukemic alkaloids from Brucea antidysenterica. 
  • Antitumor agents. 139. Synthesis and biological evaluation of thiocolchicine analogs 5,6-dihydro-6(S)-(acyloxy)- and 5,6-dihydro-6(S)-[(aroyloxy)methyl]-1,2,3-trimethoxy-9-(methylthio)-8H- cyclohepta[a]naphthalen-8-ones as novel cytotoxic and antimitotic agents. 
  • Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents. 
  • Application of high resolution fast atom bombardment and constant B/E ratio linked scanning to the identification and analysis of acylcarnitines in metabolic disease. 
  • Application of mixed spin iMQCs for temperature and chemical-selective imaging. 
  • Argininamide binding arrests global motions in HIV-1 TAR RNA: comparison with Mg2+-induced conformational stabilization. 
  • Artificial intelligence in multiparametric magnetic resonance imaging: A review. 
  • Assessing neurotoxicity from the low-dose radiation component of radiosurgery using magnetic resonance spectroscopy. 
  • Assessing right atrial function in pulmonary hypertension: window to the soul of the right heart? 
  • Assessment of 3D proton MR echo-planar spectroscopic imaging using automated spectral analysis. 
  • Assessment of citrate concentrations in citrus fruit-based juices and beverages: implications for management of hypocitraturic nephrolithiasis. 
  • Assessment of early response to tumor-treating fields in newly diagnosed glioblastoma using physiologic and metabolic MRI: initial experience. 
  • Assessment of intrahepatic triglyceride content using magnetic resonance spectroscopy. 
  • Assignment of aliphatic side-chain 1HN/15N resonances in perdeuterated proteins. 
  • Asteropsin A: an unusual cystine-crosslinked peptide from porifera enhances neuronal Ca2+ influx. 
  • Attenuated virulence of a Francisella mutant lacking the lipid A 4'-phosphatase. 
  • Atypical developmental patterns of brain chemistry in children with autism spectrum disorder. 
  • Automated spectral analysis I: formation of a priori information by spectral simulation. 
  • Automated spectral analysis II: application of wavelet shrinkage for characterization of non-parameterized signals. 
  • Automated spectral analysis III: application to in vivo proton MR spectroscopy and spectroscopic imaging. 
  • Avascular necrosis of the femoral head: morphologic assessment by MR imaging, with CT correlation. 
  • Backbone dynamics of homologous fibronectin type III cell adhesion domains from fibronectin and tenascin. 
  • Backbone dynamics of the monomeric lambda repressor denatured state ensemble under nondenaturing conditions. 
  • Base-boronated dinucleotides: synthesis and effect of N7-cyanoborane substitution on the base protons. 
  • Bayesian k -space-time reconstruction of MR spectroscopic imaging for enhanced resolution. 
  • Benign adrenal lesions mimicking malignancy on MR imaging: report of two cases. 
  • Benzoic acid glucosinolate esters and other glucosinolates from Arabidopsis thaliana. 
  • Berninamycin. 2. Products of acidic hydrolysis, methanolysis, and acetolysis of berninamycin A1. 
  • Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein. 
  • Bevacizumab: radiation combination produces restricted diffusion on brain MRI. 
  • Beyond static structures of RNA by NMR: folding, refolding, and dynamics at atomic resolution. 
  • Biochemical abnormalities of the medial temporal lobe and medial prefrontal cortex in late-life depression. 
  • Biochemical analysis of inositol phosphate kinases. 
  • Biochemical association of metabolic profile and microbiome in chronic pressure ulcer wounds. 
  • Biochemical role of the Cryptococcus neoformans ADE2 protein in fungal de novo purine biosynthesis. 
  • Bone and soft tissue lesions: diagnosis with combined H-1 MR imaging and P-31 MR spectroscopy. 
  • Brain fluoxetine measurements using fluorine magnetic resonance spectroscopy in patients with social phobia. 
  • Brain metabolite profiles of T1-hypointense lesions in relapsing-remitting multiple sclerosis. 
  • Brief report: biochemical correlates of clinical impairment in high functioning autism and Asperger's disorder. 
  • Calbindin D28K interacts with Ran-binding protein M: identification of interacting domains by NMR spectroscopy. 
  • Carbazole Alkaloids from Clausena anisum-olens: Isolation, Characterization, and Anti-HIV Evaluation. 
  • Cardiac Magnetic Resonance Feature Tracking Global Longitudinal Strain and Prognosis After Heart Transplantation. 
  • Cardioprotective effects of 70-kDa heat shock protein in transgenic mice. 
  • Cardiotonic agents. 8. Selective inhibitors of adenosine 3',5'-cyclic phosphate phosphodiesterase III. Elaboration of a five-point model for positive inotropic activity. 
  • Carrier-free 131I-meta-iodobenzylguanidine: comparison of production from meta-diazobenzylguanidine and from meta-trimethylsilylbenzylguanidine. 
  • Cascading "Triclick" functionalization of poly(caprolactone) thin films quantified via a quartz crystal microbalance. 
  • Catabolism of 4-hydroxyacids and 4-hydroxynonenal via 4-hydroxy-4-phosphoacyl-CoAs. 
  • Characterization of a microcarrier cell culture system for 23Na MR spectroscopy studies. 
  • Characterization of diffusing capacity and perfusion of the rat lung in a lipopolysaccaride disease model using hyperpolarized 129Xe. 
  • Characterization of the secondary structure of calmodulin in complex with a calmodulin-binding domain peptide. 
  • Characterizing RNA Excited States Using NMR Relaxation Dispersion. 
  • Characterizing Watson-Crick versus Hoogsteen Base Pairing in a DNA-Protein Complex Using Nuclear Magnetic Resonance and Site-Specifically 13C- and 15N-Labeled DNA. 
  • Characterizing complex dynamics in the transactivation response element apical loop and motional correlations with the bulge by NMR, molecular dynamics, and mutagenesis. 
  • Characterizing the protonation state of cytosine in transient G·C Hoogsteen base pairs in duplex DNA. 
  • Characterizing the relative orientation and dynamics of RNA A-form helices using NMR residual dipolar couplings. 
  • Chemical shift imaging of atherosclerosis at 7.0 Tesla. 
  • Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats. 
  • Cine MR determination of left ventricular ejection fraction. 
  • Clinical applications of neuroimaging in psychiatry. 
  • Clinical proton MR spectroscopy in central nervous system disorders. 
  • Co-evolving motions at protein-protein interfaces of two-component signaling systems identified by covariance analysis. 
  • Combining 'caged-dopamine' photolysis with fast-scan cyclic voltammetry to assess dopamine clearance and release autoinhibition in vitro. 
  • Community-Organized Resources for Reproducible MRS Data Analysis. 
  • Comparative analysis of normal and growth-retarded placentas with phosphorus nuclear magnetic resonance spectroscopy. 
  • Comparing MRS and PET. 
  • Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: minimal structural requirements for intermolecular complexation and fibril formation. 
  • Comprehensive analysis of the Cramer-Rao bounds for magnetic resonance temperature change measurement in fat-water voxels using multi-echo imaging. 
  • Comprehensive processing, display and analysis for in vivo MR spectroscopic imaging. 
  • Confidence images for MR spectroscopic imaging. 
  • Conformational Analysis and Molecular Modeling of 1-Phenyl-, 4-Phenyl-, and 1-Benzyl-1,2,3,4-tetrahydroiso-quinolines as D1 Dopamine Receptor Ligands 
  • Conformational analysis of a flexible oligosaccharide using residual dipolar couplings. 
  • Conformational changes of purine repressor DNA-binding domain upon complexation with DNA. 
  • Conformational kinetics reveals affinities of protein conformational states. 
  • Conformational preferences of a chimeric peptide HIV-1 immunogen from the C4-V3 domains of gp120 envelope protein of HIV-1 CAN0A based on solution NMR: comparison to a related immunogenic peptide from HIV-1 RF. 
  • Conformational selection or induced fit: a flux description of reaction mechanism. 
  • Conformational studies of dithymidine boranomonophosphate diastereoisomers. 
  • Consequences of (129)Xe-(1)H cross relaxation in aqueous solutions. 
  • Constructing atomic-resolution RNA structural ensembles using MD and motionally decoupled NMR RDCs. 
  • Continuously infusing hyperpolarized 129Xe into flowing aqueous solutions using hydrophobic gas exchange membranes. 
  • Copper-catalyzed cyclization of steroidal acylaminoacetylenes: syntheses of novel 11beta-aryl-17,17- spiro[(4'H,5'-methylene)oxazol]-substituted steroids. 
  • Correlation of Impedance Cardiography-Derived and Cardiac Magnetic Resonance-Derived Stroke Volumes. 
  • Correlation of cine MR imaging with two-dimensional pulsed Doppler echocardiography in valvular insufficiency. 
  • Counterions influence reactivity of metal ions with cysteinyldopa model compounds. 
  • Covalently bound phosphate residues in bovine milk xanthine oxidase and in glucose oxidase from Aspergillus niger: a reevaluation. 
  • Creatine kinase overexpression improves ATP kinetics and contractile function in postischemic myocardium. 
  • Creatinine kinase kinetics studied by phosphorus-31 nuclear magnetic resonance in a canine model of chronic hypertension-induced cardiac hypertrophy. 
  • Cryosurgical debulking of unresectable liver metastases for palliation of carcinoid syndrome. 
  • Cyanogenic glycosides and menisdaurin from Guazuma ulmifolia, Ostrya virgininana, Tiquilia plicata and Tiquilia canescens. 
  • Cyclization/hydrosilylation of functionalized 1,6-diynes catalyzed by cationic platinum complexes containing bidentate nitrogen ligands. 
  • Decreases in free cholesterol and fatty acid unsaturation in renal cell carcinoma demonstrated by breath-hold magnetic resonance spectroscopy. 
  • Delayed-onset movement disorder and encephalopathy after oxycodone ingestion. 
  • Demonstration that Small Molecules can Bind and Stabilize Low-abundance Short-lived RNA Excited Conformational States. 
  • Dependence of residual dipolar couplings on foot angle in (1)H MR spectra from skeletal muscle. 
  • Design, synthesis and evaluation of ¹⁵ N- and ¹³ C-labeled molecular probes as hyperpolarized nitric oxide sensors. 
  • Design, synthesis and structure relationships of new N,N',N",N"'-tetrakis (omega-amino alkyl) tetraazamacrocycles. 
  • Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. 
  • Detection and characterization of xenon-binding sites in proteins by 129Xe NMR spectroscopy. 
  • Detection of bromobenzene-induced hepatocellular necrosis using magnetic resonance microscopy. 
  • Determinants of backbone dynamics in native BPTI: cooperative influence of the 14-38 disulfide and the Tyr35 side-chain. 
  • Determination of acrylamide in rat serum and sciatic nerve by gas chromatography-electron-capture detection. 
  • Determination of separate inhibitor and substrate binding sites in the dehaloperoxidase-hemoglobin from Amphitrite ornata. 
  • Development of a YIGSR-peptide-modified polyurethaneurea to enhance endothelialization. 
  • Development of a novel series of styrylquinoline compounds as high-affinity leukotriene D4 receptor antagonists: synthetic and structure-activity studies leading to the discovery of (+-)-3-[[[3-[2-(7-chloro-2-quinolinyl)-(E)-ethenyl]phenyl][[3- (dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid. 
  • Developments in solution-state NMR yield broader and deeper views of the dynamic ensembles of nucleic acids. 
  • Diarylaniline derivatives as a distinct class of HIV-1 non-nucleoside reverse transcriptase inhibitors. 
  • Dicranin, an antimicrobial and 15-lipoxygenase inhibitor from the moss Dicranum scoparium. 
  • Differentiation of radiation fibrosis from recurrent neoplasia: a role for 31P MR spectroscopy? 
  • Direct Hyperpolarization of Nitrogen-15 in Aqueous Media with Parahydrogen in Reversible Exchange. 
  • Direct and cost-efficient hyperpolarization of long-lived nuclear spin states on universal 15N2-diazirine molecular tags 
  • Direct evidence for (G)O6···H2-N4(C)+ hydrogen bonding in transient G(syn)-C+ and G(syn)-m5C+ Hoogsteen base pairs in duplex DNA from cytosine amino nitrogen off-resonance R1ρ relaxation dispersion measurements. 
  • Direct liquid chromatography determination of the reactive imine SJG-136 (NSC 694501). 
  • Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer. 
  • Distinct patterns of fat metabolism in skeletal muscle of normal-weight, overweight, and obese humans. 
  • Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator. 
  • Dithiol Aryl Arsenic Compounds as Potential Diagnostic and Therapeutic Radiopharmaceuticals. 
  • Domain-elongation NMR spectroscopy yields new insights into RNA dynamics and adaptive recognition. 
  • Drug design from the cryptic inhibitor envelope. 
  • Dual role of glutathione in modulating camptothecin activity: depletion potentiates activity, but conjugation enhances the stability of the topoisomerase I-DNA cleavage complex. 
  • Durhamycin A, a potent inhibitor of HIV Tat transactivation. 
  • Dynamic basis for dG•dT misincorporation via tautomerization and ionization. 
  • Dynamics-based amplification of RNA function and its characterization by using NMR spectroscopy. 
  • Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction. 
  • Early recognition of Alzheimer's disease: what is consensual? What is controversial? What is practical? 
  • Early response monitoring of receptor tyrosine kinase inhibitor therapy in metastatic renal cell carcinoma using [F-18]fluorothymidine-positron emission tomography-magnetic resonance. 
  • Effect of ischemic preconditioning and PKC activation on acidification during ischemia in rat heart. 
  • Effect of poly(ethylene glycol) diacrylate concentration on network properties and in vivo response of poly(β-amino ester) networks. 
  • Effects of Alzheimer disease on fronto-parietal brain N-acetyl aspartate and myo-inositol using magnetic resonance spectroscopic imaging. 
  • Effects of age, medication, and illness duration on the N-acetyl aspartate signal of the anterior cingulate region in schizophrenia. 
  • Effects of exercise on lipoprotein particles in women with polycystic ovary syndrome. 
  • Effects of hypoxia and toxicant exposure on adenylate energy charge and cytosolic ADP concentrations in abalone. 
  • Effects of oxygen on the metabolism of murine tumors using in vivo phosphorus-31 NMR. 
  • Effects of pentobarbital anesthesia on the energy metabolism of murine tumors studied by in vivo 31P nuclear magnetic resonance spectroscopy. 
  • Effects of phenylamide herbicides on the physical properties of phosphatidylcholine membranes. 
  • Effects of pulse shaping in laser spectroscopy and nuclear magnetic resonance. 
  • Effects of regular endurance exercise on GlycA: Combined analysis of 14 exercise interventions. 
  • Effects of the amount and intensity of exercise on plasma lipoproteins. 
  • Effects of therapy on the 1H NMR spectrum of a human glioma line. 
  • Efficient acquisition of high-resolution 4-D diagonal-suppressed methyl-methyl NOESY for large proteins. 
  • Electroconvulsive therapy of depression in patients with white matter hyperintensity. 
  • Electron-nuclear double resonance studies of oxidized Escherichia coli sulfite reductase: 1H, 14N, and 57Fe measurements. 
  • Elevated prefrontal cortex γ-aminobutyric acid and glutamate-glutamine levels in schizophrenia measured in vivo with proton magnetic resonance spectroscopy. 
  • Enabling hyperpolarized (129) Xe MR spectroscopy and imaging of pulmonary gas transfer to the red blood cells in transgenic mice expressing human hemoglobin. 
  • Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists. 
  • Endogenous functional CBV contrast revealed by diffusion weighting. 
  • Enhanced nonlinear magnetic resonance signals via square wave dipolar fields. 
  • Enhanced protein flexibility caused by a destabilizing amino acid replacement in BPTI. 
  • Enthalpic signature of methonium desolvation revealed in a synthetic host-guest system based on cucurbit[7]uril. 
  • Enzymatic preparation of neomycin C from ribostamycin. 
  • Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury. 
  • Establishing an accurate gas phase reference frequency to quantify 129 Xe chemical shifts in vivo. 
  • Evaluating the quality of NMR structures by local density of protons. 
  • Evaluating the uncertainty in exchange parameters determined from off-resonance R1ρ relaxation dispersion for systems in fast exchange. 
  • Evaluation of BA1112 rhabdomyosarcoma oxygenation with microelectrodes, optical spectrophotometry, radiosensitivity, and magnetic resonance spectroscopy. 
  • Evaluation of variable line-shape models and prior information in automated 1H spectroscopic imaging analysis. 
  • Evidence against formation of A23187 dimers and oligomers in solution: photo-induced degradation of Ionophore A23187. 
  • Evidence for a role of chloroethylaziridine in the cytotoxicity of cyclophosphamide. 
  • Evidence for altered cerebellar vermis neuronal integrity in schizophrenia. 
  • Evidence for metabolism of fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A), a sevoflurane degradation product, by cysteine conjugate beta-lyase. 
  • Expanding the use of magnetic resonance in the assessment of tumor response to therapy: workshop report. 
  • Experimental characterization of intermolecular multiple-quantum coherence pumping efficiency in solution NMR. 
  • Extending the Sensitivity of CEST NMR Spectroscopy to Micro-to-Millisecond Dynamics in Nucleic Acids Using High-Power Radio-Frequency Fields. 
  • Extending the range of microsecond-to-millisecond chemical exchange detected in labeled and unlabeled nucleic acids by selective carbon R(1rho) NMR spectroscopy. 
  • Extracellular pH and P-31 magnetic resonance spectroscopic variables are related to outcome in canine soft tissue sarcomas treated with thermoradiotherapy. 
  • Fast acquisition of high resolution 4-D amide-amide NOESY with diagonal suppression, sparse sampling and FFT-CLEAN. 
  • Fast and faster: a designed variant of the B-domain of protein A folds in 3 microsec. 
  • Fatigability, Exercise Intolerance, and Abnormal Skeletal Muscle Energetics in Heart Failure. 
  • Femoral head avascular necrosis: correlation of MR imaging, radiographic staging, radionuclide imaging, and clinical findings. 
  • Femtosecond phase-coherent two-dimensional spectroscopy. 
  • Filtered backprojection for the reconstruction of a high-resolution (4,2)D CH3-NH NOESY spectrum on a 29 kDa protein. 
  • First synthesis and structural elucidation of (-)-presphaerene. 
  • Fluorine magnetic resonance spectroscopy measurement of brain fluvoxamine and fluoxetine in pediatric patients treated for pervasive developmental disorders. 
  • Focal and lateralized subcortical abnormalities in unipolar major depressive disorder: an automated multivoxel proton magnetic resonance spectroscopy study. 
  • Folding kinetics of a fluorescent variant of monomeric lambda repressor. 
  • GABA level, gamma oscillation, and working memory performance in schizophrenia. 
  • GAVA: spectral simulation for in vivo MRS applications. 
  • Generation of impossible cross-peaks between bulk water and biomolecules in solution NMR. 
  • Genetic Determinants of Circulating Lipoproteins in Nonalcoholic Fatty Liver Disease. 
  • Global brain metabolic quantification with whole-head proton MRS at 3 T. 
  • Glutamine attenuates endotoxin-induced lung metabolic dysfunction: potential role of enhanced heat shock protein 70. 
  • Glutamine-mediated attenuation of cellular metabolic dysfunction and cell death after injury is dependent on heat shock factor-1 expression. 
  • Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance. 
  • Glycogen-targeting subunits and glucokinase differentially affect pathways of glycogen metabolism and their regulation in hepatocytes. 
  • Gradient-induced longitudinal relaxation of hyperpolarized noble gases in the fringe fields of superconducting magnets used for magnetic resonance. 
  • Gray and white matter brain chemistry in young children with autism. 
  • Green polymer chemistry VIII: synthesis of halo-ester-functionalized poly(ethylene glycol)s via enzymatic catalysis. 
  • Guest exchange in an encapsulation complex: a supramolecular substitution reaction. 
  • HIV-1 leader RNA dimeric interface revealed by NMR. 
  • Heat and cold denatured states of monomeric lambda repressor are thermodynamically and conformationally equivalent. 
  • Hematopoietic and fatty bone marrow distribution in the normal and ischemic hip: new observations with 1.5-T MR imaging. 
  • Hemoglobin Raleigh (beta1 valine replaced by acetylalanine). Structural and functional characterization. 
  • Hepatic 31P magnetic resonance spectroscopy: a hepatologist's user guide. 
  • Hepatic ATP reserve and efficiency of replenishing: comparison between obese and nonobese normal individuals. 
  • Hepatic fat and adenosine triphosphate measurement in overweight and obese adults using 1H and 31P magnetic resonance spectroscopy. 
  • Hexabromonaphthalene contaminants of polybrominated biphenyls: chemical composition and disposition in the rat. 
  • Hierarchy of RNA functional dynamics. 
  • High-Density Lipoprotein Particle Subfractions in Heart Failure With Preserved or Reduced Ejection Fraction. 
  • High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size. 
  • High-level 2H/13C/15N labeling of proteins for NMR studies. 
  • High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble. 
  • High-resolution, >1 GHz NMR in unstable magnetic fields. 
  • Homogeneous NMR spectra in inhomogeneous fields. 
  • Human brain glycogen metabolism during and after hypoglycemia. 
  • Human brain-structure resolved T(2) relaxation times of proton metabolites at 3 Tesla. 
  • Human in vivo phosphate metabolite imaging with 31P NMR. 
  • Human nucleotide excision repair protein XPA: NMR spectroscopic studies of an XPA fragment containing the ERCC1-binding region and the minimal DNA-binding domain (M59-F219). 
  • Hydrogel Design of Experiments Methodology to Optimize Hydrogel for iPSC-NPC Culture 
  • Hyperpolarization of "Neat" Liquids by NMR Signal Amplification by Reversible Exchange. 
  • Hyperpolarized 3He NMR lineshape measurements in the live guinea pig lung. 
  • Hyperpolarized carbon-carbon intermolecular multiple quantum coherences. 
  • Hypoxia precedes the development of experimental preretinal neovascularization. 
  • IMDA/aldol strategy for transforming carbohydrates into functionalized trans-decalins. 
  • Identification and quantification of regioisomeric cholesteryl linoleate hydroperoxides in oxidized human low density lipoprotein and high density lipoprotein. 
  • Identification of a residue critical for maintaining the functional conformation of BPTI. 
  • Identification of an urinary metabolite profile associated with osteoarthritis. 
  • Identification of disease- and nutrient-related metabolic fingerprints in osteoarthritic Guinea pigs. 
  • Identification of epsilon-N-trimethyllysine in a rat testis calcium-dependent regulatory protein of cyclic nucleotide phosphodiesterase. 
  • Identification of undecaprenyl phosphate-beta-D-galactosamine in Francisella novicida and its function in lipid A modification. 
  • Image-guided and intensity-modulated radiosurgery for patients with spinal metastasis. 
  • Imaging genetics of brain longevity and mental wellness: the next frontier? 
  • Imaging of the chest. 
  • Imaging with intermolecular multiple-quantum coherences in solution nuclear magnetic resonance. 
  • Impact of static and dynamic A-form heterogeneity on the determination of RNA global structural dynamics using NMR residual dipolar couplings. 
  • Impact on cardiometabolic risk of a weight loss intervention with higher protein from lean red meat: Combined results of 2 randomized controlled trials in obese middle-aged and older adults. 
  • Implementing stereotactic accelerated partial breast irradiation using magnetic resonance guided radiation therapy. 
  • Improved excitation pulse bandwidths using shaped pulses, with application to heteronuclear half filters in macromolecular NMR. 
  • Improved initial value estimation for short echo time magnetic resonance spectroscopy spectral analysis using short T2 signal attenuation. 
  • Improved reconstruction stability for chemical shift encoded hyperpolarized ¹³ C magnetic resonance spectroscopic imaging using k-t spiral acquisitions. 
  • Improving calibration accuracy in gel dosimetry. 
  • In vitro and in vivo behavior of radiolabeled chimeric anti-EGFRvIII monoclonal antibody: comparison with its murine parent. 
  • In vitro characterization of vascular endothelial growth factor and dexamethasone releasing hydrogels for implantable probe coatings. 
  • In vitro metabolism of the COX-2 inhibitor DFU, including a novel glutathione adduct rearomatization. 
  • In vivo 31P MR spectral patterns and reproducibility in cancer patients studied in a multi-institutional trial. 
  • In vivo NMR detection of diet-induced changes in adipose tissue composition. 
  • In vivo brown adipose tissue detection and characterization using water-lipid intermolecular zero-quantum coherences. 
  • Increased adhesion between neutral lipid bilayers: interbilayer bridges formed by tannic acid. 
  • Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation. 
  • Increasing hyperpolarized spin lifetimes through true singlet eigenstates. 
  • Increasing the length of poly-pyrimidine bulges broadens RNA conformational ensembles with minimal impact on stacking energetics. 
  • Influence of editing pulse flip angle on J-difference MR spectroscopy. 
  • Inhibition of thermolysin by phosphonamidate transition-state analogues: measurement of 31P-15N bond lengths and chemical shifts in two enzyme-inhibitor complexes by solid-state nuclear magnetic resonance. 
  • Inhomogeneity-free heteronuclear iMQC. 
  • Insights into Watson-Crick/Hoogsteen breathing dynamics and damage repair from the solution structure and dynamic ensemble of DNA duplexes containing m1A. 
  • Insights into the nature of DNA binding of AbrB-like transcription factors. 
  • Insulin-like growth factor-1 but not growth hormone augments mammalian myocardial contractility by sensitizing the myofilament to Ca2+ through a wortmannin-sensitive pathway: studies in rat and ferret isolated muscles. 
  • Integrated MR imaging and spectroscopy with chemical shift imaging of P-31 at 1.5 T: initial clinical experience. 
  • Inter-helical conformational preferences of HIV-1 TAR-RNA from maximum occurrence analysis of NMR data and molecular dynamics simulations. 
  • Interaction of the antifolate antibiotic trimethoprim with phosphatidylcholine membranes: a 13C and 31P nuclear magnetic resonance study. 
  • International Workshop on Standardization in Clinical Magnetic Resonance Spectroscopy Measurements: proceedings and recommendations. 
  • International advances in the treatment of social phobia. 
  • International workshop on standardization in clinical MRS measurements: proceedings and recommendations. 
  • Intracellular monitoring of experimental respiratory failure. Collaborative Group on Intracellular Monitoring. 
  • Intracerebral malignant melanoma: high-field-strength MR imaging. 
  • Intrinsic disorder drives N-terminal ubiquitination by Ube2w. 
  • Intrinsic dynamics of DNA-polymer complexes: a mechanism for DNA release. 
  • Investigation of the complexes of EcoRI endonuclease with decanucleotides containing canonical and modified recognition sequences using fluorescence and optical detection of magnetic resonance spectroscopy. 
  • Investigation of the effect of acquisition schemes on time-resolved magnetic resonance fingerprinting. 
  • Invisible RNA state dynamically couples distant motifs. 
  • Is Magnetic Resonance Cholangiopancreatography Worth a Thousand Words in Determining Prognoses of Patients With Primary Sclerosing Cholangitis? 
  • Is nuclear magnetic resonance lipoprotein subclass related to diabetic retinopathy? The multi-ethnic study of atherosclerosis (MESA). 
  • Isocoproporphyrin: nuclear-magnetic-resonance-and mass-spectral methods for the determination of porphyrin structure. 
  • Isolation from the mushroom Agaricus bisporus and chemical synthesis of gamma-L-glutaminyl-4-hydroxybenzene. 
  • Kidney changes after extracorporeal shock wave lithotripsy: appearance on MR imaging. 
  • Kinetic and nuclear magnetic resonance study of the interaction of NADP+ and NADPH with chicken liver fatty acid synthase. 
  • Kleinhospitine E and Cycloartane Triterpenoids from Kleinhovia hospita. 
  • Laser-enhanced NMR spectroscopy. 
  • Layer-by-Layer Click Deposition of Functional Polymer Coatings for Combating Marine Biofouling 
  • Ligation-state hydrogen exchange: coupled binding and folding equilibria in ribonuclease P protein. 
  • Linearity, Bias, and Precision of Hepatic Proton Density Fat Fraction Measurements by Using MR Imaging: A Meta-Analysis. 
  • Localized steady-state oxygen measurements from the preretinal space of the rabbit eye using 19F NMR. 
  • Long-lived polarization protected by symmetry. 
  • Lower concentration of hippocampal N-acetylaspartate in familial bipolar I disorder. 
  • MIBG inhibits respiration: potential for radio- and hyperthermic sensitization. 
  • MR "microscopy" of the rat thorax. 
  • MR imaging and spectroscopy for prognostic evaluation in soft-tissue sarcomas. 
  • MR imaging and spectroscopy using hyperpolarized 129Xe gas: preliminary human results. 
  • MR imaging of marrow changes adjacent to end plates in degenerative lumbar disk disease. 
  • MR imaging of normal extrahepatic bile ducts. 
  • MR imaging of renal transplants. 
  • MR imaging of silicone gel-filled breast implants in vivo with a method that visualizes silicone selectively. 
  • MR imaging with hyperpolarized 3He gas. 
  • MR measurement of normal and pathologic brainstem diameters. 
  • MR spectroscopy of cholesteryl ester in human atherosclerosis. 
  • MRI of brain iron. 
  • MRI of joint fluid in the normal and ischemic hip. 
  • MRI with surface coils for parathyroid tumors: preliminary investigation. 
  • MRI/TRUS fusion vs. systematic biopsy: intra-patient comparison of diagnostic accuracy for prostate cancer using PI-RADS v2. 
  • MRS measured fatty acid composition of periprostatic adipose tissue correlates with pathological measures of prostate cancer aggressiveness. 
  • Magnetic Resonance Lymphangiography of the Central Lymphatic System: Technique and Clinical Applications. 
  • Magnetic resonance angiography with hyperpolarized 129Xe dissolved in a lipid emulsion. 
  • Magnetic resonance biomarkers in radiation oncology: The report of AAPM Task Group 294. 
  • Magnetic resonance histology of age-related nephropathy in the Sprague Dawley rat. 
  • Magnetic resonance histology. 
  • Magnetic resonance imaging at high-strength magnetic fields. 
  • Magnetic resonance imaging for the assessment of myocardial viability. 
  • Magnetic resonance imaging in the evaluation of suspected osteonecrosis of the knee. 
  • Magnetic resonance imaging of chronic myocardial infarcts in formalin-fixed human autopsy hearts. 
  • Magnetic resonance imaging of optic gliomas. 
  • Magnetic resonance imaging of pigmented villonodular synovitis: a report of two cases. 
  • Magnetic resonance microscopy of changes in water content in stems of transpiring plants. 
  • Magnetic resonance microscopy of the C57BL mouse brain. 
  • Magnetic resonance microscopy of the rat thorax and abdomen. 
  • Magnetic resonance microscopy of toxic renal injury induced by bromoethylamine in rats. 
  • Magnetic resonance spectroscopic imaging reconstruction with deformable shape-intensity models. 
  • Magnetic resonance spectroscopic studies of the prostate. 
  • Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677. 
  • Magnetic resonance spectroscopy in Alzheimer's disease: focus on N-acetylaspartate. 
  • Magnetic resonance spectroscopy in social phobia: preliminary findings. 
  • Manipulation of intra- and extracellular pH in spontaneous canine tumours by use of hyperglycaemia. 
  • Mapping staphylococcal nuclease conformation using an EDTA-Fe derivative attached to genetically engineered cysteine residues. 
  • Measurement of preretinal oxygen tension in the vitrectomized human eye using fluorine-19 magnetic resonance spectroscopy. 
  • Measurements of hyperpolarized gas properties in the lung. Part III: (3)He T(1). 
  • Measuring diffusion limitation with a perfusion-limited gas--hyperpolarized 129Xe gas-transfer spectroscopy in patients with idiopathic pulmonary fibrosis. 
  • Measuring similarity between dynamic ensembles of biomolecules. 
  • Mechanism of fast protein folding. 
  • Mechanism of palladium-catalyzed diene cyclization/hydrosilylation: direct observation of intramolecular carbometalation. 
  • Mechanism of pyranopterin ring formation in molybdenum cofactor biosynthesis. 
  • Melanin deposition in two Cryptococcus species depends on cell-wall composition and flexibility. 
  • Merged magnetic resonance and light sheet microscopy of the whole mouse brain. 
  • MetJ repressor interactions with DNA probed by in-cell NMR. 
  • Metabolic brain mapping in Alzheimer's disease using proton magnetic resonance spectroscopy. 
  • Metabolic changes in Japanese medaka (Oryzias latipes) during embryogenesis and hypoxia as determined by in vivo 31P NMR. 
  • Metabolite proton T(2) mapping in the healthy rhesus macaque brain at 3 T. 
  • Metabolomics, pathway regulation, and pathway discovery. 
  • Methodological standardization for a multi-institutional in vivo trial of localized 31P MR spectroscopy in human cancer research. In vitro and normal volunteer studies. 
  • Methodology for the measurement and analysis of relaxation times in proton imaging. 
  • Mg2+-induced variations in the conformation and dynamics of HIV-1 TAR RNA probed using NMR residual dipolar couplings. 
  • Microemulsions of cholesteryl oleate and dimyristoylphosphatidylcholine: a model for cholesteryl ester rich very low density lipoproteins. 
  • Microtesla SABRE enables 10% nitrogen-15 nuclear spin polarization. 
  • Mitochondrial NADH as the bellwether of tissue O2 delivery. 
  • Mitochondrial localization and characterization of 99Tc-SESTAMIBI in heart cells by electron probe X-ray microanalysis and 99Tc-NMR spectroscopy. 
  • Modulation of Hoogsteen dynamics on DNA recognition. 
  • Molecular imaging for depressive disorders. 
  • Molecular stress relief through a force-induced irreversible extension in polymer contour length. 
  • Molecular symmetry as an aid to geometry determination in ligand protein complexes. 
  • Motion-resolved and free-breathing liver MRF. 
  • Multiaxial fields improve SABRE efficiency by preserving hydride order. 
  • Multisection proton MR spectroscopy for mesial temporal lobe epilepsy. 
  • Multisite multivendor validation of a quantitative MRI and CT compatible fat phantom. 
  • Multi‑organ assessment via a 9.4‑Tesla MRS evaluation of metabolites during the embryonic development of cleft palate induced by dexamethasone. 
  • Muscle activity localization with 31P spectroscopy and calculated T2-weighted 1H images. 
  • Myocardial Contractile Mechanics in Ischemic Mitral Regurgitation: Multicenter Data Using Stress Perfusion Cardiovascular Magnetic Resonance. 
  • Myocardial Steatosis Among Antiretroviral Therapy-Treated People With Human Immunodeficiency Virus Participating in the REPRIEVE Trial. 
  • Myoepithelioma of the parotid. Report of a case initially examined by fine needle aspiration biopsy. 
  • N-methylated 5-alkenyloxazolium salt transformations. 
  • NIfTI-MRS: A standard data format for magnetic resonance spectroscopy. 
  • NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P. 
  • NMR assignment of the N-terminal repeat domain of Bacillus subtilis ClpC. 
  • NMR of hyperpolarized (129)Xe in the canine chest: spectral dynamics during a breath-hold. 
  • NMR rheotomography: feasibility and clinical potential. 
  • NMR structural characterization of the CDK inhibitor p19INK4d. 
  • NMR structure of AbhN and comparison with AbrBN: FIRST insights into the DNA binding promiscuity and specificity of AbrB-like transition state regulator proteins. 
  • NMR structures of biomolecules using field oriented media and residual dipolar couplings. 
  • NMR studies of RNA dynamics and structural plasticity using NMR residual dipolar couplings. 
  • NMR studies of a complex of deuterated calmodulin with melittin. 
  • NMR studies of an immunomodulatory benzodiazepine binding to its molecular target on the mitochondrial F(1)F(0)-ATPase. 
  • NMR studies of combined lanthanide shift and relaxation agents for differential characterization of 23Na in a two-compartment model system. 
  • NMR studies of nucleic acid dynamics. 
  • NMR studies of structure, hydrogen exchange, and main-chain dynamics in a disrupted-core mutant of thioredoxin. 
  • NMR-derived solution conformations of a hybrid synthetic peptide containing multiple epitopes of envelope protein gp120 from the RF strain of human immunodeficiency virus. 
  • Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. 
  • New Strategies and Challenges in Lung Proteomics and Metabolomics. An Official American Thoracic Society Workshop Report. 
  • New azacannabinoids highly active in the central nervous system. 
  • New perspectives on techniques for the clinical psychiatrist: Brain stimulation, chronobiology and psychiatric brain imaging. 
  • Nitric oxide-releasing polyurethane-PEG copolymer containing the YIGSR peptide promotes endothelialization with decreased platelet adhesion. 
  • Noninvasive differentiation of tumors with use of localized H-1 spectroscopy in vivo: initial experience in patients with cerebral tumors. 
  • Normal prostate and adjacent structures: MR imaging at 1.5 T. 
  • Novel plasma biomarkers improve discrimination of metabolic health independent of weight. 
  • Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: relation to specificity of peptide-induced anti-HIV neutralizing antibodies. 
  • Nuclear magnetic resonance spectroscopy: a review of neuropsychiatric applications. 
  • Nuclear magnetic resonance spectroscopy: new insights into the pathophysiology of mood disorders. 
  • Nuclear magnetic resonance study of ligand binding to Mn-aspartate transcarbamylase. 
  • Numerical simulation of PRESS localized MR spectroscopy. 
  • Numerical studies of intermolecular multiple quantum coherences: high-resolution NMR in inhomogeneous fields and contrast enhancement in MRI. 
  • O-Alkyl dioleoylphosphatidylcholinium compounds: the effect of varying alkyl chain length on their physical properties and in vitro DNA transfection activity. 
  • Observation of coupled 1H metabolite resonances at long TE. 
  • On the localization of ubiquinone in phosphatidylcholine bilayers. 
  • On the specificity of creatine kinase. New glycocyamines and glycocyamine analogs related to creatine. 
  • Optimized MR imaging for polyacrylamide gel dosimetry. 
  • Optimized isotropic diffusion weighting. 
  • Optimized, unequal pulse spacing in multiple echo sequences improves refocusing in magnetic resonance. 
  • Osteopetrosis: MR characteristics at 1.5 T. 
  • Over 20% (15)N Hyperpolarization in Under One Minute for Metronidazole, an Antibiotic and Hypoxia Probe. 
  • Overexpression of the cardiac beta(2)-adrenergic receptor and expression of a beta-adrenergic receptor kinase-1 (betaARK1) inhibitor both increase myocardial contractility but have differential effects on susceptibility to ischemic injury. 
  • Oxygen kinetics in preretinal perfluorotributylamine. 
  • Oxygen kinetics in the vitreous substitute perfluorotributylamine: a 19F NMR study in vivo. 
  • Oxygenated norethindrone derivatives from incubation with beagle liver. Structure, synthesis, and biological activity. 
  • PEGylated gold nanoparticles conjugated to monoclonal F19 antibodies as targeted labeling agents for human pancreatic carcinoma tissue. 
  • Parkinson plus syndrome: diagnosis using high field MR imaging of brain iron. 
  • Pathogenesis of Cryptococcus neoformans is associated with quantitative differences in multiple virulence factors. 
  • Pathogenic Mutations Induce Partial Structural Changes in the Native β-Sheet Structure of Transthyretin and Accelerate Aggregation. 
  • Peak alignment of urine NMR spectra using fuzzy warping. 
  • Phase coherent excitation of SABRE permits simultaneous hyperpolarization of multiple targets at high magnetic field. 
  • Phosphorus 31 magnetic resonance spectroscopy of perifused human placental villi under varying oxygen concentrations. 
  • Physiological Fitness and the Pathophysiology of Chronic Lymphocytic Leukemia (CLL). 
  • Physiological basis for potassium (39K) magnetic resonance imaging of the heart. 
  • Polycystic ovaries: MR imaging. 
  • Prediction of cognitive decline in early Alzheimer's disease. 
  • Predictive and prognostic role of functional imaging of head and neck squamous cell carcinomas. 
  • Preorganized secondary structure as an important determinant of fast protein folding. 
  • Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid. 
  • Probing Watson-Crick and Hoogsteen base pairing in duplex DNA using dynamic nuclear polarization solid-state NMR spectroscopy. 
  • Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation. 
  • Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress. 
  • Profound increase in viscosity and aggregation of pig gastric mucin at low pH. 
  • Prognostic Value of Myocardial Damage in Patients With Sarcoidosis: Is Cardiac Magnetic Resonance What We Need? 
  • Prognostic Value of Stress Cardiac Magnetic Resonance in Patients With Known Coronary Artery Disease. 
  • Prostatic disorders: MR imaging at 1.5 T. 
  • Protein dynamic studies move to a new time slot. 
  • Proton NMR of Escherichia coli sulfite reductase: studies of the heme protein subunit with added ligands. 
  • Proton NMR of Escherichia coli sulfite reductase: the unligated hemeprotein subunit. 
  • Proton Therapy for Brain Metastases: A Question of Value. 
  • Proton magnetic resonance spectroscopic imaging in childhood ataxia with diffuse central nervous system hypomyelination. 
  • Proton magnetic resonance spectroscopy and gadolinium-DTPA perfusion imaging of asymptomatic MRI white matter lesions. 
  • Proton magnetic resonance studies of the aggregation of taurine-conjugated bile salts. 
  • Proton nuclear magnetic resonance assignments and structural characterization of an intramolecular DNA triplex. 
  • Proton spectroscopy of human brain: effects of age and sex. 
  • Proton-decoupled phosphorus-31 magnetic resonance spectroscopy in the evaluation of native and well-functioning transplanted kidneys. 
  • Protonated base pairs explain the ambiguous pairing properties of O6-methylguanine. 
  • Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives. 
  • Purification, characterization, and structural elucidation of the active moiety of the previously called "suppressor activating factor (SAF)". 
  • Qualitative and Quantitative Neuropathology Approaches Using Magnetic Resonance Microscopy (Diffusion Tensor Imaging) and Stereology in a Hexachlorophene Model of Myelinopathy in Sprague-Dawley Rats. 
  • Quantification of contrast in clinical MR brain imaging at high magnetic field. 
  • Quantification of hepatic steatosis with a multistep adaptive fitting MRI approach: prospective validation against MR spectroscopy. 
  • Quantitation of Total PFAS Including Trifluoroacetic Acid with Fluorine Nuclear Magnetic Resonance Spectroscopy. 
  • Quantitation of automated single-voxel proton MRS using cerebral water as an internal reference. 
  • Quantitation of proton NMR spectra of the human brain using tissue water as an internal concentration reference. 
  • Quantitative 1H magnetic resonance spectroscopic imaging determines therapeutic immunization efficacy in an animal model of Parkinson's disease. 
  • Quantitative determination of the partial oxygen pressure in the vitrectomized rabbit eye in vivo using 19F NMR. 
  • Quantitative proton MR spectroscopic imaging of the human brain. 
  • Quantitative proton spectroscopy and histology of a canine brain tumor model. 
  • Quantitative proton spectroscopy of canine brain: in vivo and in vitro correlations. 
  • Quantum treatment of intermolecular multiple-quantum coherences with intramolecular J coupling in solution NMR. 
  • RNA Structural Modules Control the Rate and Pathway of RNA Folding and Assembly. 
  • RNA dynamics by design: biasing ensembles towards the ligand-bound state. 
  • RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins. 
  • Rabbit and human liver contain a novel pentacyclic triterpene ester with acyl-CoA: cholesterol acyltransferase inhibitory activity. 
  • Racial differences of lipoprotein subclass distributions in postmenopausal women. 
  • Radial sampling for fast NMR: Concepts and practices over three decades. 
  • Radiation therapy and hyperthermia improve the oxygenation of human soft tissue sarcomas. 
  • Radical prostatectomy: value of prostate MRI in surgical planning. 
  • Radiolabeled guanine derivatives for the in vivo mapping of O(6)-alkylguanine-DNA alkyltransferase: 6-(4-[(18)F]Fluoro-benzyloxy)-9H-purin-2-ylamine and 6-(3-[(131)I]Iodo-benzyloxy)-9H-purin-2-ylamine. 
  • Randomized, placebo-controlled trial of the effects of donepezil on neuronal markers and hippocampal volumes in Alzheimer's disease. 
  • Rapid Exchange Between Free and Bound States in RNA-Dendrimer Polyplexes: Implications on the Mechanism of Delivery and Release. 
  • Rapid Recognition and Targeted Isolation of Anti-HIV Daphnane Diterpenes from Daphne genkwa Guided by UPLC-MSn. 
  • Rapid calculation of T1 using variable flip angle gradient refocused imaging. 
  • Rapid determination of protein folds using residual dipolar couplings. 
  • Reagents for astatination of biomolecules: comparison of the in vivo distribution and stability of some radioiodinated/astatinated benzamidyl and nido-carboranyl compounds. 
  • Recommendations on the Use of Multimodality Cardiovascular Imaging in Young Adult Competitive Athletes: A Report from the American Society of Echocardiography in Collaboration with the Society of Cardiovascular Computed Tomography and the Society for Cardiovascular Magnetic Resonance. 
  • Reconstruction of porous material geometry by stochastic optimization based on bulk NMR measurements of the dipolar field. 
  • Referencing strategy for the direct comparison of nuclear magnetic resonance and molecular dynamics motional parameters in RNA. 
  • Regional metabolite T2 in the healthy rhesus macaque brain at 7T. 
  • Relation between pO2, 31P magnetic resonance spectroscopy parameters and treatment outcome in patients with high-grade soft tissue sarcomas treated with thermoradiotherapy. 
  • Relationships between in vivo and in vitro measurements of metabolism in young and old human calf muscles. 
  • Renal allograft rejection: evaluation by Doppler US and MR imaging. 
  • Representation of strong baseline contributions in 1H MR spectra. 
  • Reproducibility of 3D proton spectroscopy in the human brain. 
  • Reproducibility of high spatial resolution proton magnetic resonance spectroscopic imaging in the human brain. 
  • Reproducibility of relaxation and spin-density parameters in phantoms and the human brain measured by MR imaging at 1.5 T. 
  • Reproductive cytotoxicity is predicted by magnetic resonance microscopy and confirmed by ubiquitin-proteasome immunohistochemistry in a theophylline-induced model of rat testicular and epididymal toxicity. 
  • Residual dipolar coupling derived orientational constraints on ligand geometry in a 53 kDa protein-ligand complex. 
  • Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics. 
  • Respiratory effects in two-dimensional Fourier transform MR imaging. 
  • Results and interpretation of a fitting challenge for MR spectroscopy set up by the MRS study group of ISMRM. 
  • Revisiting the mean-field picture of dipolar effects in solution NMR. 
  • Ring current effects in adriamycin-flavin mononucleotide complexation as observed by 1H FT NMR spectroscopy. 
  • Robust analysis of short echo time (1)H MRSI of human brain. 
  • Role of cardiac magnetic resonance (CMR) in planning ventricular septal myomectomy in patients with hypertrophic obstructive cardiomyopathy (HOCM). 
  • Rotational isomers of N-alkylpyridylporphyrins and their metal complexes. HPLC separation, (1)H NMR and X-ray structural characterization, electrochemistry, and catalysis of O(2)(.-) disproportionation. 
  • SABRE enhancement with oscillating pulse sequences. 
  • STRUCTURE OF STREPTOLYDIGIN. 
  • Sampling of the NMR time domain along concentric rings. 
  • Secondary structure of a leucine zipper determined by nuclear magnetic resonance spectroscopy. 
  • Selecting a noninvasive imaging study after an inconclusive exercise test. 
  • Sequence-specific B-DNA flexibility modulates Z-DNA formation. 
  • Short TE in vivo (1)H MR spectroscopic imaging at 1.5 T: acquisition and automated spectral analysis. 
  • Short echo time multislice proton magnetic resonance spectroscopic imaging in human brain: metabolite distributions and reliability. 
  • Signal enhancement in CRAZED experiments. 
  • Signal irreproducibility in high-field solution magnetic resonance experiments caused by spin turbulence. 
  • Simultaneous acquisition of multiple orders of intermolecular multiple-quantum coherence images in vivo. 
  • Simultaneous acquisition of multiple orders of intermolecular multiple-quantum coherence images. 
  • Single-voxel 1H PRESS at 4.0 T: precision and variability of measurements in anterior cingulate and hippocampus. 
  • Skeletal muscle pH assessed by biochemical and 31P-MRS methods during exercise and recovery in men. 
  • Society for Cardiovascular Magnetic Resonance 2020 Case of the Week series. 
  • Society for Cardiovascular Magnetic Resonance 2021 cases of SCMR and COVID-19 case collection series. 
  • Society for cardiovascular magnetic resonance recommendations for training and competency of CMR technologists. 
  • Soft-tissue sarcomas: MR imaging and MR spectroscopy for prognosis and therapy monitoring. Work in progress. 
  • Soft-tissue sarcomas: detection of metabolic heterogeneity with P-31 MR spectroscopy. 
  • Solid state thermal degradation products of rosaramicin. 
  • Solid-phase synthesis for the identification of high-affinity bivalent lectin ligands. 
  • Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction. 
  • Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3. 
  • Sparsely sampled high-resolution 4-D experiments for efficient backbone resonance assignment of disordered proteins. 
  • Spectroscopic evidence for anthracenedione antineoplastic agent self-association and complex formation with flavin nucleotides. 
  • Spectroscopy: shifting light with spin. 
  • Spin-echo magnetic resonance spectroscopic imaging at 7 T with frequency-modulated refocusing pulses. 
  • Stereochemistry and mechanism of the Brønsted acid catalyzed intramolecular hydrofunctionalization of an unactivated cyclic alkene. 
  • Sticking points in magnetic resonance diagnosis of constrictive pericarditis. 
  • Stimulus/secretion coupling factors in glucose-stimulated insulin secretion: insights gained from a multidisciplinary approach. 
  • Stressed enough? Hyperaemic thresholds during quantitative cardiovascular magnetic resonance perfusion mapping. 
  • Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. 
  • Structural anisotropy and internal magnetic fields in trabecular bone: coupling solution and solid dipolar interactions. 
  • Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) ζ, and Pol κ. 
  • Structural characterization of a molybdopterin precursor. 
  • Structural characterization of the conformational change in calbindin-D28k upon calcium binding using differential surface modification analyzed by mass spectrometry. 
  • Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain. 
  • Structural dynamics of a single-stranded RNA-helix junction using NMR. 
  • Structural neuroimaging of geriatric depression. 
  • Structure and DNA-binding traits of the transition state regulator AbrB. 
  • Structure and biological activity of (-)-[3H]dihydroalprenolol, a radioligand for studies of beta-adrenergic receptors. 
  • Structure and biosynthesis of free lipid A molecules that replace lipopolysaccharide in Francisella tularensis subsp. novicida. 
  • Structure and function of the visual arrestin oligomer. 
  • Structure and phase behavior of lipid suspensions containing phospholipids with covalently attached poly(ethylene glycol). 
  • Structure and stability of monomeric lambda repressor: NMR evidence for two-state folding. 
  • Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity. 
  • Structure of a G.T.A triplet in an intramolecular DNA triplex. 
  • Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein. 
  • Structure of an HIV-1-neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimer. 
  • Structure of macromolecular aggregates. II. Construction of model membranes from phospholipids and polypeptides. 
  • Structure of the smooth muscle myosin light-chain kinase calmodulin-binding domain peptide bound to calmodulin. 
  • Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymerase eta. 
  • Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D(28K). 
  • Structure-activity studies of 2,3,4,4a,5,9b-hexahydroindeno[1,2-c]pyridines as antispermatogenic agents for male contraception. 
  • Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the kappa-opioid receptor. 
  • Structure-function relationships of the complement regulatory protein, CD59. 
  • Sublethal effects of pentachlorophenol in abalone (Haliotis rufescens) veliger larvae as measured by (31)P-NMR. 
  • Submillisecond folding of monomeric lambda repressor. 
  • Suppression of conformational heterogeneity at a protein-protein interface. 
  • Synthesis and biological activity of saccharide based lipophilic siderophore mimetics as potential growth promoters for mycobacteria. 
  • Synthesis and biological activity of zoapatanol analogues. 
  • Synthesis and evaluation of 18F- and 11C-labeled phenyl-galactopyranosides as potential probes for in vivo visualization of LacZ gene expression using positron emission tomography. 
  • Synthesis and preliminary evaluation of para- and meta-[18F]fluorobenzylguanidine. 
  • Synthesis of P(1)-Citronellyl-P(2)-alpha-D-pyranosyl pyrophosphates as potential substrates for the E. coli undecaprenyl-pyrophosphoryl-N-acetylglucoseaminyl transferase MurG. 
  • Synthesis of carbobicyclic compounds via palladium-catalyzed cyclization/hydrosilylation: evidence for reversible silylpalladation. 
  • Synthesis of new 2'-deoxy-2'-fluoro-4'-azido nucleoside analogues as potent anti-HIV agents. 
  • Synthesis of new classes of boron-containing nucleotides. 
  • Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection. 
  • Synthesis of prodrug candidates: conjugates of amino acid with nucleoside boranophosphate. 
  • Synthesis, characterization, and bioavailability of mannosylated shell cross-linked nanoparticles. 
  • Synthesis, characterization, and cyclic stress-influenced degradation of a poly(ethylene glycol)-based poly(beta-amino ester). 
  • Synthesis, siderophore activity and iron(III) chelation chemistry of a novel mono-hydroxamate, bis-catecholate siderophore mimic: N(alpha),-N(epsilon)-Bis[2,3-dihydroxybenzoyl]-l-lysyl-(gamma-N-methyl-N-hydroxyamido)-L-glutamic acid. 
  • Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors. 
  • Systematic solution to homo-oligomeric structures determined by NMR. 
  • T1 rho relaxation and its application to MR histology. 
  • T1rho imaging using magnetization-prepared projection encoding (MaPPE). 
  • T2 relaxation times of macromolecules and metabolites in the human brain at 9.4 T. 
  • Tau induces formation of α-synuclein filaments with distinct molecular conformations. 
  • Techniques for high-speed cardiac magnetic resonance imaging in rats and rabbits. 
  • Temperature-dependent molecular motions of cholesterol esters: a carbon-13 nuclear magnetic resonance study. 
  • Template-based docking of a prolactin receptor proline-rich motif octapeptide to FKBP12: implications for cytokine receptor signaling. 
  • The Elusive 5'-Deoxyadenosyl Radical: Captured and Characterized by Electron Paramagnetic Resonance and Electron Nuclear Double Resonance Spectroscopies. 
  • The MotA protein from bacteriophage T4 contains two domains. Preliminary structural analysis by X-ray diffraction and nuclear magnetic resonance. 
  • The activation domain of the MotA transcription factor from bacteriophage T4. 
  • The effect of a probiotic on hepatic steatosis. 
  • The energy landscape of a fast-folding protein mapped by Ala-->Gly substitutions. 
  • The hydrogen bonding of cytosine with guanine: calorimetric and 1H-nmr analysis of the molecular interactions of nucleic acid bases. 
  • The molecular basis for complexation of adriamycin with flavin mononucleotide and flavin adenine dinucleotide. 
  • The protein surface is a moving target. 
  • The pterin component of the molybdenum cofactor. Structural characterization of two fluorescent derivatives. 
  • The role of nuclear magnetic resonance imaging in psychiatric research. 
  • The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus. 
  • The structure and function of pyruvate kinase. 
  • The structure of a molybdopterin precursor. Characterization of a stable, oxidized derivative. 
  • The structure of the molybdenum cofactor. Characterization of di-(carboxamidomethyl)molybdopterin from sulfite oxidase and xanthine oxidase. 
  • Therapy monitoring in human and canine soft tissue sarcomas using magnetic resonance imaging and spectroscopy. 
  • Thermodynamic effects of reduction of the active-site disulfide of Escherichia coli thioredoxin explored by differential scanning calorimetry. 
  • Thermodynamics of RNA melting, one base pair at a time. 
  • Three-dimensional MR microscopy with large arrays. 
  • Three-dimensional MRI microscopy of the normal rat brain. 
  • Three-dimensional magnetic resonance microscopy of the developing chick embryo. 
  • Thyroid imaging with high-field-strength surface-coil MR. 
  • Time course and mechanism of alterations in proton relaxation during liver regeneration in the rat. 
  • Time-resolved magnetic resonance fingerprinting for radiotherapy motion management. 
  • Tissue relaxation time: in vivo field dependence. 
  • Toward Hyperpolarized ¹⁹ F Molecular Imaging via Reversible Exchange with Parahydrogen. 
  • Transient Hoogsteen base pairs in canonical duplex DNA. 
  • Transition metal-chelate complexes as relaxation modifiers in nuclear magnetic resonance. 
  • Truncated sinc slice excitation for 31P spectroscopic imaging. 
  • Two-second MR images: comparison with spin-echo images in 29 patients. 
  • Unbiased measurements of reconstruction fidelity of sparsely sampled magnetic resonance spectra. 
  • Understanding of basic mechanisms of beta-cell function and survival: prelude to new diabetes therapies. 
  • Uniform 13C isotope labeling of proteins with sodium acetate for NMR studies: application to human carbonic anhydrase II. 
  • Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc. 
  • Unveiling Inherent Degeneracies in Determining Population-Weighted Ensembles of Interdomain Orientational Distributions Using NMR Residual Dipolar Couplings: Application to RNA Helix Junction Helix Motifs. 
  • Unveiling coherently driven hyperpolarization dynamics in signal amplification by reversible exchange. 
  • Use of gel filtration in the preparation of biological fluids for magnetic resonance spectroscopy. 
  • Use of phosphorus ligand NMR probes to investigate electronic and second-sphere solvent effects in ligand substitution reactions at manganese(II) and manganese(III). 
  • Using fluorine nuclear magnetic resonance to probe changes in the structure and dynamics of membrane-active peptides interacting with lipid bilayers. 
  • Using fluorine nuclear magnetic resonance to probe the interaction of membrane-active peptides with the lipid bilayer. 
  • Utility of functional imaging in prediction or assessment of treatment response and prognosis following thermotherapy. 
  • Utilizing in vivo nuclear magnetic resonance spectroscopy to study sublethal stress in aquatic organisms. 
  • Validation of 19F-magnetic resonance determination of myocardial blood volume. 
  • Value of Late Gadolinium Enhancement Imaging in Diagnosis of Myocardial Infarction and Unobstructed Coronary Arteries. 
  • Variability in billing practices for whole-body magnetic resonance imaging: reply to Degnan et al. 
  • Variable helix elongation as a tool to modulate RNA alignment and motional couplings. 
  • Variation of molecular alignment as a means of resolving orientational ambiguities in protein structures from dipolar couplings. 
  • Ventilation-synchronous magnetic resonance microscopy of pulmonary structure and ventilation in mice. 
  • Visual activation in alpha-chloralose-anaesthetized cats does not cause lactate accumulation in the visual cortex as detected by [1H]NMR difference spectroscopy. 
  • Visualizing the formation of an RNA folding intermediate through a fast highly modular secondary structure switch. 
  • Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes. 
  • Water exchange rates of water-soluble manganese(III) porphyrins of therapeutical potential. 
  • Water mobility within bovine cervical mucus. 
  • Whole-Brain N-Acetylaspartate Concentration Is Preserved during Mild Hypercapnia Challenge. 
  • Why are Hoogsteen base pairs energetically disfavored in A-RNA compared to B-DNA? 
  • Widespread transient Hoogsteen base pairs in canonical duplex DNA with variable energetics. 
  • X-ray crystal structure of acrovestone, a cytotoxic principle from Acronychia pedunculata. 
  • cis-parthenolid-9-one from Anvillea garcinii. 
  • p-Amidino esters as irreversible inhibitors of factors IXa and Xa and thrombin. 
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  Keywords of People

  • Charles, Hal Cecil, Adjunct Associate Professor in the Department of Radiology, Radiology
  • Chitneni, Satish K., Associate Professor in Radiology, Radiology
  • Driehuys, Bastiaan, Professor of Radiology, Biomedical Engineering
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Guan, Ziqiang, Research Professor in Biochemistry, Biochemistry
  • Johnson, G. Allan, Charles E. Putman University Distinguished Professor of Radiology, Biomedical Engineering
  • Oas, Terrence Gilbert, Professor of Biochemistry, Biochemistry
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology