Nucleic Acid Heteroduplexes
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Subject Areas on Research
- Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae.
- Atomic force microscopy captures the initiation of methyl-directed DNA mismatch repair.
- Boranophosphates support the RNase H cleavage of polyribonucleotides.
- Characterization of a defective phage system for the analysis of bacteriophage T4 DNA replication origins.
- Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae.
- Cytosine deamination in mismatched base pairs.
- DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair.
- DNA strand-exchange patterns associated with double-strand break-induced and spontaneous mitotic crossovers in Saccharomyces cerevisiae.
- Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair.
- Elongation by Drosophila RNA polymerase II. Transcription of 3'-extended DNA templates.
- Extensive recombination due to heteroduplexes generates large amounts of artificial gene fragments during PCR.
- Genetic evidence for preferential strand transfer during meiotic recombination in yeast.
- Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break.
- Genetic subtyping of human immunodeficiency virus using a heteroduplex mobility assay.
- Heteroduplex DNA position defines the roles of the Sgs1, Srs2, and Mph1 helicases in promoting distinct recombination outcomes.
- High-resolution mapping of heteroduplex DNA formed during UV-induced and spontaneous mitotic recombination events in yeast.
- Hypermutability and mismatch repair deficiency in RER+ tumor cells.
- Measurements of excision repair tracts formed during meiotic recombination in Saccharomyces cerevisiae.
- Meiotic recombination between dispersed repeated genes is associated with heteroduplex formation.
- Meiotic recombination involving heterozygous large insertions in Saccharomyces cerevisiae: formation and repair of large, unpaired DNA loops.
- Meiotic recombination within the centromere of a yeast chromosome.
- Methyl-directed repair of DNA base-pair mismatches in vitro. 1983.
- Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes.
- Mismatch repair in replication fidelity, genetic recombination, and cancer biology.
- Mismatch repair-dependent iterative excision at irreparable O6-methylguanine lesions in human nuclear extracts.
- Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-encoded protein.
- Mispair specificity of methyl-directed DNA mismatch correction in vitro.
- Modulation of MutS ATP hydrolysis by DNA cofactors.
- Molecular structures of crossover and noncrossover intermediates during gap repair in yeast: implications for recombination.
- MutS mediates heteroduplex loop formation by a translocation mechanism.
- Mutation detection with MutH, MutL, and MutS mismatch repair proteins.
- Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair.
- Patterns of heteroduplex formation associated with the initiation of meiotic recombination in the yeast Saccharomyces cerevisiae.
- RNA-DNA hybrid formation at a bacteriophage T4 replication origin.
- Regulation of hetDNA Length during Mitotic Double-Strand Break Repair in Yeast.
- Repair of DNA loops involves DNA-mismatch and nucleotide-excision repair proteins.
- Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae.
- Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast.
- Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.
- The effect of a single boranophosphate substitution with defined configuration on the thermal stability and conformation of a DNA duplex.
- The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast.
- Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes.
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Keywords of People
- Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
- Kearney, Hutton Moore, Assistant Consulting Professor in the Department of Pathology, Pathology