Subject Areas on Research
- A genetically defined insula-brainstem circuit selectively controls motivational vigor.
- A role for the CD38 rs3796863 polymorphism in alcohol and monetary reward: evidence from CD38 knockout mice and alcohol self-administration, [11C]-raclopride binding, and functional MRI in humans.
- A role for ΔFosB in calorie restriction-induced metabolic changes.
- Activation of Glutamatergic Fibers in the Anterior NAc Shell Modulates Reward Activity in the aNAcSh, the Lateral Hypothalamus, and Medial Prefrontal Cortex and Transiently Stops Feeding.
- Activity patterns in mesolimbic regions in rats during operant tasks for reward.
- Adeno-associated virus-mediated ILK gene silencing in the rat NAc core.
- Adolescent morphine exposure affects long-term microglial function and later-life relapse liability in a model of addiction.
- Altered cocaine potency in the nucleus accumbens following 7-day withdrawal from intermittent but not continuous treatment: voltammetric assessment of dopamine uptake in the rat.
- Anatomically dissociable effects of dopamine D1 receptor agonists on reward and relief of withdrawal in morphine-dependent rats.
- Antidepressant actions of histone deacetylase inhibitors.
- Appetitive changes during salt deprivation are paralleled by widespread neuronal adaptations in nucleus accumbens, lateral hypothalamus, and central amygdala.
- Behavioral and molecular effects of dopamine D1 receptor stimulation during naloxone-precipitated morphine withdrawal.
- Behavioral, but not reward, risk modulates activation of prefrontal, parietal, and insular cortices.
- Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm.
- Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens.
- Cocaine acts on accumbens monoamines and locomotor behavior via a 5-HT2A/2C receptor mechanism as shown by ketanserin: 24-h follow-up studies.
- Cocaine alters Homer1 natural antisense transcript in the nucleus accumbens.
- Cocaine increases stimulated dopamine release more in periadolescent than adult rats.
- Cocaine self-administration reduces excitatory responses in the mouse nucleus accumbens shell.
- Cocaine shapes chromatin landscapes via Tet1.
- Cognitive Neurostimulation: Learning to Volitionally Sustain Ventral Tegmental Area Activation.
- Concurrent autoreceptor-mediated control of dopamine release and uptake during neurotransmission: an in vivo voltammetric study.
- D1 and D2 antagonists reverse the effects of appetite suppressants on weight loss, food intake, locomotion, and rebalance spiking inhibition in the rat NAc shell.
- DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses.
- Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat.
- Disrupted Prefrontal Regulation of Striatal Subjective Value Signals in Psychopathy.
- Dopamine Neurons That Cotransmit Glutamate, From Synapses to Circuits to Behavior.
- Dorsolateral prefrontal cortex drives mesolimbic dopaminergic regions to initiate motivated behavior.
- Early nurture epigenetically tunes the oxytocin receptor.
- Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression.
- Elevations of FosB in the nucleus accumbens during forced cocaine abstinence correlate with divergent changes in reward function.
- Extracellular acetylcholine is increased in the nucleus accumbens following the presentation of an aversively conditioned taste stimulus.
- FACS analysis of neuronal-glial interactions in the nucleus accumbens following morphine administration.
- Feedback-Based Learning in Aging: Contributions and Trajectories of Change in Striatal and Hippocampal Systems.
- Food reward in the absence of taste receptor signaling.
- Genetic Risk for Rheumatoid Arthritis is Associated with Increased Striatal Volume in Healthy Young Adults.
- Genetic, epigenetic, and environmental factors controlling oxytocin receptor gene expression.
- Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls.
- Impact of acute nicotine exposure on monoaminergic systems in adolescent and adult male and female rats.
- Kappa-Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials.
- LTP in the mouse nucleus accumbens is developmentally regulated.
- Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania.
- MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants.
- Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats.
- Morphine exposure alters Fos expression in a sex-, age-, and brain region-specific manner during adolescence.
- Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway.
- Multimodal characterization of the human nucleus accumbens.
- Neural Mechanisms of Emotion Regulation in Autism Spectrum Disorder.
- Neuro-anatomic mapping of dopamine D1 receptor involvement in nicotine self-administration in rats.
- Neurotensin interacts with dopaminergic neurons in rat brain.
- Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated excitation of ventral tegmental area dopamine neurons and dopamine release in the nucleus accumbens.
- Nicotinic, muscarinic and dopaminergic actions in the ventral hippocampus and the nucleus accumbens: effects on spatial working memory in rats.
- Noradrenergic Signaling Disengages Feedforward Transmission in the Nucleus Accumbens Shell.
- Nucleus Accumbens AMPA Receptors Are Necessary for Morphine-Withdrawal-Induced Negative-Affective States in Rats.
- Opioid Self-Administration is Attenuated by Early-Life Experience and Gene Therapy for Anti-Inflammatory IL-10 in the Nucleus Accumbens of Male Rats.
- Parvalbumin Interneurons of the Mouse Nucleus Accumbens are Required For Amphetamine-Induced Locomotor Sensitization and Conditioned Place Preference.
- Prefrontal cortex output circuits guide reward seeking through divergent cue encoding.
- Prenatal opioid exposure inhibits microglial sculpting of the dopamine system selectively in adolescent male offspring.
- ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine.
- Recovery of presynaptic dopaminergic functioning in rats treated with neurotoxic doses of methamphetamine.
- Regulation and function of MeCP2 Ser421 phosphorylation in U50488-induced conditioned place aversion in mice.
- Relative accuracy and reproducibility of regional MRI brain volumes for point-counting methods.
- Reversal of cocaine sensitization-induced behavioral sensitization normalizes GAD67 and GABAA receptor alpha2 subunit expression, and PKC zeta activity.
- Reversal of cocaine-induced behavioral sensitization and associated phosphorylation of the NR2B and GluR1 subunits of the NMDA and AMPA receptors.
- Reward-guided learning beyond dopamine in the nucleus accumbens: the integrative functions of cortico-basal ganglia networks.
- Reward-motivated learning: mesolimbic activation precedes memory formation.
- Sleep deprivation elevates expectation of gains and attenuates response to losses following risky decisions.
- Subcortical shape in pediatric and adult obsessive-compulsive disorder.
- Sustained anterior cingulate cortex activation during reward processing predicts response to psychotherapy in major depressive disorder.
- Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: development of central cannabinoid receptor ligands with lower lipophilicity.
- Tetrabenazine, an amine-depleting drug, also blocks dopamine receptors in rat brain.
- The neural underpinnings of how reward associations can both guide and misguide attention.
- The role of ΔfosB in the medial preoptic area: Differential effects of mating and cocaine history.
- Time-dependent recovery from the effects of 6-hydroxydopamine lesions of the rat nucleus accumbens on cocaine self-administration and the levels of dopamine in microdialysates.
- Transitions between sleep and feeding states in rat ventral striatum neurons.
- TrkB signaling is required for behavioral sensitization and conditioned place preference induced by a single injection of cocaine.
- Variability in nucleus accumbens activity mediates age-related suboptimal financial risk taking.
- White-Matter Tract Connecting Anterior Insula to Nucleus Accumbens Correlates with Reduced Preference for Positively Skewed Gambles.
- Zonisamide prevents olanzapine-associated hyperphagia, weight gain, and elevated blood glucose in rats.
- fMRI of alterations in reward selection, anticipation, and feedback in major depressive disorder.
Keywords of People
- Huettel, Scott, Professor in the Department of Psychology and Neuroscience, Duke Science & Society