Ocular Hypertension

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  Subject Areas on Research

  • A Long-term Safety Study of Latanoprost in Pediatric Patients With Glaucoma and Ocular Hypertension: A Prospective Cohort Study. 
  • A comparison of Icare PRO and Tono-Pen XL tonometers in anesthetized children. 
  • A multicenter, retrospective pilot study of resource use and costs associated with severity of disease in glaucoma. 
  • A randomised, controlled comparison of latanoprostene bunod and latanoprost 0.005% in the treatment of ocular hypertension and open angle glaucoma: the VOYAGER study. 
  • Accuracy of international classification of diseases, ninth revision, clinical modification billing codes for common ophthalmic conditions. 
  • Alpha-fodrin is cleaved by caspase-3 in a chronic ocular hypertensive (COH) rat model of glaucoma. 
  • An assessment of the health and economic burdens of glaucoma. 
  • Anti-fibrotic activity of a rho-kinase inhibitor restores outflow function and intraocular pressure homeostasis. 
  • Artifacts in spectral-domain optical coherence tomography measurements in glaucoma. 
  • Artificial neural network-based glaucoma diagnosis using retinal nerve fiber layer analysis. 
  • Association between intraocular pressure variation and glaucoma progression: data from a United States chart review. 
  • Association of Diabetes With Central Corneal Thickness Among a Multiethnic Asian Population. 
  • Association of an Objective Structural and Functional Reference Standard for Glaucoma with Quality of Life Outcomes. 
  • Association of intraocular pressure and myopia in children. 
  • Autophagy in the Aging and Experimental Ocular Hypertensive Mouse Model. 
  • Baseline risk factors for the development of primary open-angle glaucoma in the Ocular Hypertension Treatment Study. 
  • Baseline visual field characteristics in the ocular hypertension treatment study. 
  • Blood Pressure and Glaucomatous Progression in a Large Clinical Population. 
  • Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension. 
  • Central corneal thickness and its relationship to intraocular pressure in children. 
  • Central corneal thickness and measured IOP response to topical ocular hypotensive medication in the Ocular Hypertension Treatment Study. 
  • Central corneal thickness in normal, glaucomatous, and ocular hypertensive eyes. 
  • Central corneal thickness in the Ocular Hypertension Treatment Study (OHTS). 
  • Central corneal thickness. 
  • Cerebrospinal fluid pressure trends in diseases associated with primary open-angle glaucoma. 
  • Classification of visual field abnormalities in the ocular hypertension treatment study. 
  • Clinical comparison of the Proview eye pressure monitor with the Goldmann applanation tonometer and the Tonopen. 
  • Clinical comparison of the proview eye pressure monitor with the Goldmann Applanation Tonometer and the TonoPen. 
  • Confirmation of visual field abnormalities in the Ocular Hypertension Treatment Study. Ocular Hypertension Treatment Study Group. 
  • Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms. 
  • Corneal thickness and applanation pressure. 
  • Correlation among retinal thickness, optic disc, and visual field in glaucoma patients and suspects: a pilot study. 
  • Current understanding of conventional outflow dysfunction in glaucoma. 
  • Determinants of image quality of Heidelberg Retina Tomography II and its association with optic disc parameters in a population-based setting. 
  • Development and validation of a machine learning, smartphone-based tonometer. 
  • Diagnostic accuracy of the Heidelberg Retina Tomograph for glaucoma a population-based assessment. 
  • Differential response and withdrawal profile of glucocorticoid-treated human trabecular meshwork cells. 
  • Diffuse glaucomatous structural and functional damage in the hemifield without significant pattern loss. 
  • Discovery and Preclinical Development of Netarsudil, a Novel Ocular Hypotensive Agent for the Treatment of Glaucoma. 
  • Disease progression in iridocorneal angle tissues of BMP2-induced ocular hypertensive mice with optical coherence tomography. 
  • Distribution of amyloid precursor protein and amyloid-beta in ocular hypertensive C57BL/6 mouse eyes. 
  • Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States. 
  • Early rapid rise in intraocular pressure after intravitreal triamcinolone acetonide injection. 
  • Effect of U74006F (Tirilazad Mesylate) in rabbit eyes after argon laser trabeculoplasty. 
  • Effect of corneal arcus on central corneal thickness, intraocular pressure, and primary open-angle glaucoma: the Singapore Malay Eye Study. 
  • Effects of Netarsudil and Latanoprost Alone and in Fixed Combination on Corneal Endothelium and Corneal Thickness: Post-Hoc Analysis of MERCURY-2. 
  • Elevated intraocular pressure induces Rho GTPase mediated contractile signaling in the trabecular meshwork. 
  • Evaluation of the ICare rebound tonometer as a home intraocular pressure monitoring device. 
  • Factors associated with elevated intraocular pressure in eyes with iris melanoma. 
  • Fixed-Dose Combination of Netarsudil and Latanoprost in Ocular Hypertension and Open-Angle Glaucoma: Pooled Efficacy/Safety Analysis of Phase 3 MERCURY-1 and -2. 
  • Gene and protein expression pilot profiling and biomarkers in an experimental mouse model of hypertensive glaucoma. 
  • Glaucoma Cascade Screening in a High Risk Afro-Caribbean Haitian Population: A Pilot Study. 
  • Glaucoma Progression Analysis software compared with expert consensus opinion in the detection of visual field progression in glaucoma. 
  • Glaucoma-Related Adverse Events in the First 5 Years After Unilateral Cataract Removal in the Infant Aphakia Treatment Study. 
  • Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure. 
  • Home tonometry for management of pediatric glaucoma. 
  • Home tonometry in childhood glaucoma: clinical indications and physician and parental attitudes. 
  • Icare rebound tonometry in children with known and suspected glaucoma. 
  • Impact of Artifacts From Optical Coherence Tomography Retinal Nerve Fiber Layer and Macula Scans on Detection of Glaucoma Progression. 
  • Incidence and Management of Glaucoma or Glaucoma Suspect in the First Year After Pediatric Lensectomy. 
  • Incidence of Glaucoma-Related Adverse Events in the First 5 Years After Pediatric Lensectomy. 
  • Incidence of Management Changes at the Postoperative Week 1 Visit after Cataract Surgery: Results from the Perioperative Care for IntraOcular Lens Study. 
  • Influence of height, weight, and body mass index on optic disc parameters. 
  • Insidious-onset, non-wheezing carteolol-induced asthma in an atopic patient without asthma history. 
  • Integral role for lysyl oxidase-like-1 in conventional outflow tissue function and behavior. 
  • Interplay between intraocular and intracranial pressure effects on the optic nerve head in vivo. 
  • Intracranial pressure in primary open angle glaucoma, normal tension glaucoma, and ocular hypertension: a case-control study. 
  • Intraocular pressure in children: the effect of body position as assessed by Icare and Tono-Pen tonometers. 
  • Intraocular pressure in patients with uveitis treated with fluocinolone acetonide implants. 
  • Latanoprost and brimonidine: therapeutic and physiologic assessment before and after oral nonsteroidal anti-inflammatory therapy. 
  • Latanoprost for the treatment of pediatric glaucoma. 
  • Latanoprost systemic exposure in pediatric and adult patients with glaucoma: a phase 1, open-label study. 
  • Long-term Safety and Ocular Hypotensive Efficacy Evaluation of Netarsudil Ophthalmic Solution: Rho Kinase Elevated IOP Treatment Trial (ROCKET-2). 
  • Longitudinal Change in Central Corneal Thickness in the Tema Eye Survey. 
  • Longitudinal changes in central corneal thickness and their relation to glaucoma status: an 8 year follow up study. 
  • Longitudinal reproducibility of optical coherence tomography measurements in children. 
  • Management of glaucoma drainage implant tube kink and obstruction with Pars Plana Clip. 
  • Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. 
  • Measuring intraocular pressure-adjustments for corneal thickness and new technologies. 
  • Netarsudil Improves Trabecular Outflow Facility in Patients with Primary Open Angle Glaucoma or Ocular Hypertension: A Phase 2 Study. 
  • Netarsudil/Latanoprost Fixed-Dose Combination for Elevated Intraocular Pressure: Three-Month Data from a Randomized Phase 3 Trial. 
  • New Insight of Common Regulatory Pathways in Human Trabecular Meshwork Cells in Response to Dexamethasone and Prednisolone Using an Integrated Quantitative Proteomics: SWATH and MRM-HR Mass Spectrometry. 
  • Normal visual field test results following glaucomatous visual field end points in the Ocular Hypertension Treatment Study. 
  • Novel software strategy for glaucoma diagnosis: asymmetry analysis of retinal thickness. 
  • OCULAR HYPERTENSION AFTER INTRAVITREAL INJECTION OF 2-MG TRIAMCINOLONE. 
  • Optical coherence tomography in paediatric glaucoma: time domain versus spectral domain. 
  • Optogenetic Modulation of Intraocular Pressure in a Glucocorticoid-Induced Ocular Hypertension Mouse Model. 
  • Paradoxical intraocular pressure elevation after combined therapy with latanoprost and bimatoprost. 
  • Philadelphia Telemedicine Glaucoma Detection and Follow-up Study: Analysis of Unreadable Fundus Images. 
  • Philadelphia Telemedicine Glaucoma Detection and Follow-up Study: Methods and Screening Results. 
  • Pilocarpine-induced dilation of Schlemm's canal and prevention of lumen collapse at elevated intraocular pressures in living mice visualized by OCT. 
  • Pooled Efficacy and Safety Profile of Netarsudil Ophthalmic Solution 0.02% in Patients With Open-angle Glaucoma or Ocular Hypertension. 
  • Pressure phosphene self-tonometry: a comparison with goldmann tonometry in glaucoma patients. 
  • Primary Open-Angle Glaucoma Suspect Preferred Practice Pattern®. 
  • Primary cilia and the reciprocal activation of AKT and SMAD2/3 regulate stretch-induced autophagy in trabecular meshwork cells. 
  • Rates of glaucoma medication utilization among older adults with suspected glaucoma, 1992 to 2002. 
  • Rats! Hyperglycemia protects against glaucoma! 
  • Reduction of IOP after PRK. 
  • Refractive errors, intraocular pressure, and glaucoma in a white population. 
  • Results of trabeculectomy combined with phacoemulsification versus trabeculectomy combined with extracapsular cataract extraction in patients with advanced glaucoma. 
  • Retinal vascular caliber and age-related macular degeneration in an Indian population from Singapore. 
  • Retinal vascular geometry and glaucoma: the Singapore Malay Eye Study. 
  • Retinal vessel diameter and open-angle glaucoma: the Blue Mountains Eye Study. 
  • Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats. 
  • RhoA GTPase-induced ocular hypertension in a rodent model is associated with increased fibrogenic activity in the trabecular meshwork. 
  • Role of corneal elasticity in damping of intraocular pressure. 
  • Role of the autotaxin-lysophosphatidic acid axis in glaucoma, aqueous humor drainage and fibrogenic activity. 
  • Shared Cared for Stable Glaucoma Patients: Economic Benefits and Patient-centered Outcomes of a Feasibility Trial. 
  • Steroid-induced ocular hypertension/glaucoma: Focus on pharmacogenomics and implications for precision medicine. 
  • The African Descent and Glaucoma Evaluation Study (ADAGES): design and baseline data. 
  • The Effect of Age on Increasing Susceptibility to Retinal Nerve Fiber Layer Loss in Glaucoma. 
  • The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. 
  • The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. 
  • The Ocular Hypertension Treatment Study: design and baseline description of the participants. 
  • The Ocular Hypertension Treatment Study: reproducibility of cup/disk ratio measurements over time at an optic disc reading center. 
  • The Ocular Hypertension Treatment Study: topical medication delays or prevents primary open-angle glaucoma in African American individuals. 
  • The Relationship of Vogt-Koyanagi-Harada Syndrome to Ocular Hypertension and Glaucoma. 
  • The development of a decision analytic model of changes in mean deviation in people with glaucoma: the COA model. 
  • The fine structure of an iridectomy specimen from a patient with latanoprost-induced eye color change. 
  • The impact of intraocular pressure reduction on retinal ganglion cell function measured using pattern electroretinogram in eyes receiving latanoprost 0.005% versus placebo. 
  • The impact of retardance pattern variability on nerve fiber layer measurements over time using GDx with variable and enhanced corneal compensation. 
  • The natural history of glaucoma and ocular hypertension after pediatric cataract surgery. 
  • The relation of retinal microvascular characteristics to age-related eye disease: the Beaver Dam eye study. 
  • Tortuous Pore Path Through the Glaucomatous Lamina Cribrosa. 
  • Ultrastructural changes associated with dexamethasone-induced ocular hypertension in mice. 
  • Using the arteriolar Pressure Attenuation Index to predict ocular hypertension progression to open-angle glaucoma. 
  • VEGF as a Paracrine Regulator of Conventional Outflow Facility. 
  • eNOS, a pressure-dependent regulator of intraocular pressure. 
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  Keywords of People

  • Farsiu, Sina, Professor in the Department of Biomedical Engineering, Electrical and Computer Engineering
  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics